Apply Michael Feathers-inspired legacy-code rules when changing hard-to-test code safely with characterization tests, seams, sprout methods, or wrap methods.
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概要と使いどころ
Apply Michael Feathers-inspired legacy-code rules when changing hard-to-test code safely with characterization tests, seams, sprout methods, or wrap methods.
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Configures AWS WAF to filter web traffic: creating web access control lists (web ACLs) on CloudFront, Application Load Balancers, API Gateway, and AppSync; AWS Managed Rules tuned in Count mode; rate-based rules for HTTP floods; IP set and geographic match rules; Bot Control (Common and Targeted); turning bot labels into a confidence signal; stripping spoofed inbound x-amzn-waf-* headers; recovering the real client IP behind a CDN; Fraud Control (account takeover and account creation fraud prevention); and logging and request sampling. Use when the user wants to protect a web application or API from common exploits, bots, credential stuffing, fake-account creation, or HTTP floods at the application layer (layer 7). Routes to the right per-task procedure in references. Do NOT use for L3/L4 DDoS protection (shieldadvanced skill), multi-account WAF rollout (firewallmanager skill), CloudFront configuration (cloudfront skill), or Route 53 health checks or records (route53 skill).
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Generates the Methods section for a meta-analysis paper, including search strategy, screening, quality assessment, data extraction, and statistical analysis.
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Migrate Spring Security 5 to Spring Security 6 configuration. Use when removing WebSecurityConfigurerAdapter, replacing @EnableGlobalMethodSecurity with @EnableMethodSecurity, converting antMatchers to requestMatchers, or updating to lambda DSL configuration style. Covers SecurityFilterChain beans and authentication manager changes.
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Guide for translating Python classes, inheritance, and object-oriented patterns to Scala. Use when converting Python code with classes, dataclasses, abstract classes, inheritance, properties, static methods, class methods, or design patterns.
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Design Thinking method coaching knowledge across all nine methods including per-method techniques, deep expertise, and industry context (energy, financial services, healthcare, manufacturing, nonprofit and social impact, pharmaceuticals and life sciences, professional services, public sector, retail and CPG)
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Use when planning or building the whole Bethesda modpack incrementally — batch strategy, rollback point, naming convention, separator discipline, attribution, and declaring 风格 before adding mods. Triggers - "build a modpack", "plan the pack", "batch strategy", "rollback point", "naming convention", "declare 风格", "策展整合包", "整合包规划". NOT for deciding whether one mod belongs (evaluating-bgs-mods), installing one mod from author instructions (interpreting-mod-author-instructions), load order mechanics (writing-bgs-load-order), or record conflicts (xedit-conflict-audit).
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Use when deciding whether a mod belongs in a modpack — judging mod quality, fit, risk, and pack-value BEFORE download/install. Triggers - "should I add this mod", "is this mod good", "评估这个mod", "这个mod值得装吗", "is this mod worth it", "this mod looks too good to be true", "compare these mods", "does this mod fit my pack". NOT for how to install a mod (use interpreting-mod-author-instructions), load order (writing-bgs-load-order), or conflict resolution (xedit-conflict-audit).
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Use when deciding what characterization and experimental detail an Advanced Materials manuscript must show to prove its structure–property claim, and what belongs in the Experimental Section and Supporting Information. Partitions and stress-tests methods; does not design figures or run analysis.
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Organize DI registrations using IServiceCollection extension methods. Group related services into composable Add* methods for clean Program.cs and reusable configuration in tests.
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Calls m6A peaks from MeRIP-seq / m6A-seq paired IP-vs-input data using exomePeak2 (transcript-aware, GC-bias-corrected Poisson GLM), MeTPeak (HMM over sliding windows), MACS3/MACS2 with --nomodel --broad --keep-dup all (genome-wide broad alternative), and DRACH motif enrichment via HOMER or ggseqlogo as a sanity check (NOT a filter). Covers BED12 vs narrowPeak output, exonic vs intronic peak handling, multi-tool reconciliation (intersection vs union), the m6A-vs-m6Am ambiguity at 5'UTR peaks that antibody methods cannot resolve, and orthogonal validation (miCLIP/GLORI/m6A-SAC-seq/m6Anet). Use when calling peaks from paired IP/input genome BAMs, choosing exomePeak2 (transcript-aware default) vs MACS3 (broad genomic) vs MeTPeak (HMM-smoothed low-coverage), confirming DRACH enrichment as a sanity check on the peak set, reconciling differing peak sets across tools, validating MeRIP peaks against single-base methods, interpreting 5' peaks where m6Am contamination is possible, or recommending a consensus strategy.
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Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.
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Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger, MR-PRESSO, MR-RAPS, CAUSE, LHC-MR, LCV, MR-Clust, MR-Mix, and contamination-mixture methods. Use when validating an MR causal claim, running the STROBE-MR sensitivity battery, suspecting a shared heritable confounder, working under weak-instrument or polygenic-exposure regimes, or reconciling discordant estimates across robust methods.
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Compile a PAM control's iOS Obj-C/Swift module into the FLAT device-slice `.framework` for a `.ppmplugin` bundle (never an `.xcframework` — the wrap CI won't descend into one). Mac-only (Xcode). Builds from a throwaway staged copy so canonical `ios/` and the podspec stay untouched, references React-Core headers only (React is weak-linked and provided by the wrap host at runtime, no CocoaPods), generates the required umbrella header, module map and Info.plist, sets the critical build settings, asserts manifest conformance, then runs a device-only `xcodebuild archive` and copies out the flat framework to `ppmplugin/staging/ios/`. Known limitation — the React weak-link flags aren't yet validated against a live wrap host and the RN pin must match the host's. Run after /generate-ppmplugin-manifest for an iOS or Both target, before /assemble-ppmplugin.
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Debug Kubernetes pods, nodes, and workloads. Use when pods are failing, containers crash, nodes are unhealthy, or users mention debugging, troubleshooting, or diagnosing Kubernetes issues.
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Diagnose NCCL failures and adjacent training-pod failures on HyperPod GPU clusters (EKS or Slurm) — training hangs, AllReduce / collective-op timeouts, EFA or libfabric errors, rendezvous failures, EFA TCP fallback, /dev/shm or memlock issues, NCCL version mismatch across pods, container OOM / exit-137 / OOMKilled, GPU OOM (CUDA out of memory), CrashLoopBackOff / Pending pods, MASTER_ADDR DNS, NetworkPolicy blocking. Not for single-node hardware faults (→ hyperpod-node-debugger § G) or cluster-creation EFA / SSM failures (→ hyperpod-cluster-debugger § A / § F).
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Complete sanctions and export control analysis tool — individual designations, sectoral sanctions, dual-use goods, payment systems (SWIFT/USD), and extraterritorial regimes (EAR/ITAR/ FDPR US, ECL China). Triggers: "is X sanctioned?", "can I do business with X?", "can I sell Y to Z?", "pétrole Russie", "biens à double usage", "gel des avoirs", "sanctions internationales", "liste OFAC", "liste UE", "double usage", "embargo", "licence d'exportation", "SWIFT", "paiement en dollars", "US goods", "FDPR", "EAR", "ITAR", "BIS", "ECL chine", "no re-export clause", "sanctions sectorielles", "puis-je travailler avec X?", or any transaction involving a foreign person, product, sector, destination country, or payment in USD/EUR. Always adapt to user profile. Always run for any sanctions or export control query — even vague or exploratory ones.
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The scDblFinder package gathers various methods for the detection and handling of doublets/multiplets in single-cell sequencing data (i.e. multiple cells captured within the same droplet or reaction volume). It includes methods formerly fou
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Implements a variety of methods for batch correction of single-cell (RNA sequencing) data. This includes methods based on detecting mutually nearest neighbors, as well as several efficient variants of linear regression of the log-expression
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A package for demultiplexing single-cell sequencing experiments of pooled cells labeled with barcode oligonucleotides. The package implements methods to fit regression mixture models for a probabilistic classification of cells, including multiplet detection. Demultiplexing error rates can be estimated, and methods for quality control are provided.
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hoodscanR is an user-friendly R package providing functions to assist cellular neighborhood analysis of any spatial transcriptomics data with single-cell resolution. All functions in the package are built based on the SpatialExperiment object, allowing integration into various spatial transcriptomics-related packages from Bioconductor. The package can result in cell-level neighborhood annotation output, along with funtions to perform neighborhood colocalization analysis and neighborhood-based ce
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Provides methods to convert between Python AnnData objects and SingleCellExperiment objects. These are primarily intended for use by downstream Bioconductor packages that wrap Python methods for single-cell data analysis. It also includes f
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Next.js version migrations using official guides and codemods. Use when migrating a Next.js project to a new major version using codemods.
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Use free built-in .NET maintainability analyzers and code metrics configuration to find overly complex methods and coupled code. USE FOR: the team wants to find overly complex methods; cyclomatic complexity thresholds are needed in CI; maintainability metrics or coupling thresholds need to be configured. DO NOT USE FOR: formatting-only work; generic analyzer setup with no complexity policy change. INVOKES: inspect the repository context, edit targeted files, and run relevant build, test, lint, or validation commands when changes are made.
日本語の概要は準備中です。原文の説明を表示しています。