Rank and prioritize neoantigen/epitope candidates by likely T-cell response using NeoFox feature annotation, PRIME2.0, BigMHC-IM, the Łuksza/Balachandran fitness model (agretopicity + foreignness), and pVACtools tiering. Encodes the field's hard truths that immunogenicity is the least-solved layer (dedicated scores ~AUROC 0.6-0.7, modest PPV), that scores are valid only for RANKING within one patient (never absolute go/no-go or cross-patient), that DAI has anchor-inflation and WT-denominator traps, and that stacking weak correlated scores into one number is a red flag. Use when ordering a candidate list for a vaccine. Binding lives in mhc-binding-prediction; calling in neoantigen-prediction.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Decides how to preprocess plasma cfDNA sequencing data so the recoverable signal survives - library-prep-aware fragment expectations (dsDNA vs ssDNA/adaptase prep), UMI/duplex consensus with fgbio (ExtractUmisFromBam, GroupReadsByUmi --strategy paired for duplex, CallMolecularConsensusReads vs CallDuplexConsensusReads, FilterConsensusReads min-reads "total s1 s2"), the align->group->consensus->RE-align ordering, and the cfDNA dedup trap where naive coordinate dedup collapses nucleosome-coincident independent molecules. Covers when single-strand consensus suffices vs when duplex is mandatory, the singleton/sensitivity tax at low input, and reading the insert-size histogram as a pre-analytical QC instrument. Use when processing plasma cfDNA reads before fragmentomics, ctDNA mutation calling, or tumor-fraction estimation.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Corrects fluorophore spillover (conventional compensation) or spectral overlap (spectral unmixing) and applies variance-stabilizing transforms (logicle/biexponential, arcsinh, log) for flow and mass cytometry. Covers spillover-matrix estimation from single-stain controls, AutoSpill, the spillover spreading matrix and why panel design (not compensation) bounds resolution, compensate-then-transform ordering, and arcsinh cofactor choice (5 for CyTOF, ~150 for fluorescence, per-channel via flowVS). Use when correcting spectral overlap, preparing data for gating/clustering, choosing logicle vs arcsinh, deciding a cofactor, or distinguishing compensation from spectral unmixing.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Quality control for flow, spectral, and mass cytometry - time-based anomaly cleaning (flowAI, flowCut, PeacoQC, flowClean), margin/boundary event removal, signal-drift detection, dead-cell exclusion, CyTOF Gaussian/DNA/event-length checks, instrument calibration/standardization (MESF, CS&T, peak-2), and batch-level outlier flagging. Use when assessing acquisition quality, choosing a cleaning tool, ordering QC relative to compensation, deciding margin removal before density-based steps, or flagging problematic samples before clustering or differential analysis.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Build OncoPrint and co-mutation matrix plots from somatic-variant cohorts using ComplexHeatmap, maftools, and comut.py with alteration-type stacking, sample ordering by mutational burden, mutual-exclusivity overlays, and clinical annotation tracks. Use when visualizing per-sample mutation patterns across recurrent driver genes, comparing alteration classes, or identifying mutually-exclusive / co-occurring driver pairs.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Build clustered heatmaps for expression matrices and other features-by-samples data with rigorous distance/linkage/scaling choices, robust color mapping, optimal leaf ordering, and ComplexHeatmap/pheatmap/seaborn rendering. Covers the ward.D vs ward.D2 trap, the row-vs-column scaling decision, multi-track annotations, oncoPrint, and raster rendering for large matrices. Use when visualizing expression patterns across samples or identifying co-regulated clusters.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Build CarPlay-enabled apps using the CarPlay framework. Use when creating navigation, audio, communication, EV charging, parking, or food ordering apps for the car display, working with CPTemplateApplicationScene, CPInterfaceController template hierarchies, CPListTemplate, CPMapTemplate, CPNowPlayingTemplate, configuring CarPlay entitlements, or integrating with CarPlay Simulator for testing.
日本語の概要は準備中です。原文の説明を表示しています。
dpearson2699/swift-ios-skills☆ 1,1922026年8月1日 更新
Optimize App Store product pages for search visibility and conversion. Use for App Store Optimization (ASO), keyword research, app name/subtitle/keyword-field strategy, conversion-focused descriptions and promotional text, screenshot captions and ordering, Custom Product Pages with assigned search keywords, In-App Events, Product Page Optimization tests, localized metadata, ratings/review strategy, and in-app review prompt timing with RequestReviewAction or AppStore.requestReview. Also use when routing ASO vs App Store review, privacy/ATT, or StoreKit implementation boundaries.
日本語の概要は準備中です。原文の説明を表示しています。
dpearson2699/swift-ios-skills☆ 1,1922026年8月1日 更新
AWS SQS message queue service for decoupled architectures. Use when creating queues, configuring dead-letter queues, managing visibility timeouts, implementing FIFO ordering, or integrating with Lambda.
日本語の概要は準備中です。原文の説明を表示しています。
itsmostafa/aws-agent-skills☆ 1,1622026年10月13日 更新
Turn raw MATLAB code into a published .mltbx toolbox — full pipeline from scope definition through packaging and release. Drives 8 phases with human checkpoints, enforcing ordering and dependencies. Use when asked to package, create a toolbox, or run the files-to-package pipeline.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1572026年10月9日 更新
Generate database seed scripts with realistic sample data. Reads Drizzle schemas or SQL migrations, respects foreign key ordering, produces idempotent TypeScript or SQL seed files. Handles D1 batch limits, unique constraints, and domain-appropriate data. Use when populating dev/demo/test databases. Triggers: 'seed database', 'seed data', 'sample data', 'populate database', 'db seed', 'test data', 'demo data', 'generate fixtures'.
日本語の概要は準備中です。原文の説明を表示しています。
jezweb/claude-skills☆ 1,0582026年10月9日 更新
Use when writing or editing a SKILL.md, a skill's references/*.md, or an agent definition in this repo — required frontmatter, section ordering, the GDScript-then-C# example convention, and C# parity exemptions.
日本語の概要は準備中です。原文の説明を表示しています。
jame581/GodotPrompter☆ 8152026年10月12日 更新
This skill should be used when the user asks to "build a feature", "create a spec", "start spec-driven development", "run research phase", "generate requirements", "create design", "plan tasks", "implement spec", "check spec status", "triage a feature", "create an epic", "decompose a large feature", or needs guidance on spec-driven development workflow, phase ordering, or epic orchestration.
日本語の概要は準備中です。原文の説明を表示しています。
tzachbon/smart-ralph☆ 5592026年9月16日 更新
Use when the user wants a single-file HTML presentation that stays editable in the browser after generation, or needs object-level layout editing, slide reordering, local save/export, or PPT/PDF-to-web conversion with continued editing.
日本語の概要は準備中です。原文の説明を表示しています。
archlizheng/frontend-slides-editable☆ 5292026年7月1日 更新
Implements drag-and-drop and sortable interfaces with React/TypeScript including kanban boards, sortable lists, file uploads, and reorderable grids. Use when building interactive UIs requiring direct manipulation, spatial organization, or touch-friendly reordering.
日本語の概要は準備中です。原文の説明を表示しています。
ancoleman/ai-design-components☆ 5252025年12月11日 更新
DO NOT INVOKE when the primary request explicitly asks to convert, migrate, modernize, or rewrite a legacy/old-style project to SDK style; use msbuild-modernization. Migration prompts often mention ToolsVersion, explicit Compile/Reference entries, packages.config, or Microsoft.CSharp.targets, but merely reviewing or auditing a file that contains those patterns remains in scope here. USE FOR broad review, audit, lint, or maintainability/correctness checks of project/build files, including custom targets; prioritized cross-cutting findings; discrete anti-patterns; F# ordering/FS0039; cross-platform paths; and focused Import safety verdicts. Review/audit is analysis-only unless fixes are requested. For concrete property/item defects use property-patterns/item-management; use target-authoring for implementation and extension-points for NuGet auto-import/layout discovery. Exclude non-MSBuild systems.
日本語の概要は準備中です。原文の説明を表示しています。
managedcode/dotnet-skills☆ 4862026年10月13日 更新
Write, review, or modernize F# code in .NET repositories with functional-first design, algebraic data types, pattern matching, pipelines, async workflows, project ordering, and C# interop. USE FOR: F# .fs/.fsproj code; discriminated unions, records, options, results, pattern matching, computation expressions, or functional domain modeling; strongly typed AI-generated .NET code. DO NOT USE FOR: C# language modernization; FSI-only exploratory scripts with no project changes. INVOKES: inspect .fsproj file order and SDK settings, edit F# source and project files, and run dotnet build/test or dotnet fsi validation commands when changes are made.
日本語の概要は準備中です。原文の説明を表示しています。
managedcode/dotnet-skills☆ 4862026年10月13日 更新
Use when you need to add or review Mongock MongoDB data migrations in a Micronaut application — including Mongock runner/driver selection, Micronaut bean wiring, migration scan packages, @ChangeUnit classes, lock/transaction settings, and Testcontainers verification. This should trigger for requests such as Add Mongock migrations in Micronaut; Review Micronaut MongoDB data migrations; Configure Mongock change units with Micronaut Data MongoDB; Create Mongock change units for Micronaut MongoDB; Review Mongock migration ordering in a Micronaut service. Part of Plinth Toolkit
日本語の概要は準備中です。原文の説明を表示しています。
jabrena/plinth☆ 4482026年10月13日 更新
Use when you need to add or review Mongock MongoDB data migrations in a Quarkus application — including the Quarkiverse Mongock extension, Quarkus MongoDB client configuration, migrate-at-start, @ChangeUnit classes, lock/transaction settings, and Quarkus test verification. This should trigger for requests such as Add Mongock migrations in Quarkus; Configure quarkus-mongock; Review Quarkus MongoDB data migrations; Create Mongock change units for Quarkus MongoDB; Review Mongock migration ordering in a Quarkus service. Part of Plinth Toolkit
日本語の概要は準備中です。原文の説明を表示しています。
jabrena/plinth☆ 4482026年10月13日 更新
Use when you need to add or review Flyway database migrations in a Micronaut application — micronaut-flyway, db/migration scripts, flyway.datasources.* configuration, and alignment with JDBC or Micronaut Data. This should trigger for requests such as Add or review Flyway migrations in a Micronaut project; Configure micronaut-flyway or db/migration layout; Add versioned Flyway SQL migrations for Micronaut; Review Micronaut database migration ordering; Configure Flyway datasources in a Micronaut project. Part of Plinth Toolkit
日本語の概要は準備中です。原文の説明を表示しています。
jabrena/plinth☆ 4482026年10月13日 更新
Use when you need to add or review Flyway database migrations in a Spring Boot application — Maven dependencies, db/migration scripts, spring.flyway.* configuration, baseline and validation, and alignment with JDBC or Spring Data JDBC. This should trigger for requests such as Add or review Flyway migrations in a Spring Boot project; Configure spring.flyway or db/migration layout; Add versioned Flyway SQL migrations for Spring Boot; Review Spring Boot database migration ordering; Fix repeatable Flyway migrations in a Spring project. Part of Plinth Toolkit
日本語の概要は準備中です。原文の説明を表示しています。
jabrena/plinth☆ 4482026年10月13日 更新
Use when you need to add or review Mongock MongoDB data migrations in a Spring Boot application — including Maven coordinates, Spring Data MongoDB drivers, migration scan packages, @ChangeUnit classes, lock/transaction settings, and optional policy-approved MongoDB integration verification. This should trigger for requests such as Add Mongock migrations in Spring Boot; Review Spring MongoDB data migrations; Configure Mongock change units for Spring Data MongoDB; Create Mongock change units for Spring Boot MongoDB; Review Mongock migration ordering in a Spring service. Part of Plinth Toolkit
日本語の概要は準備中です。原文の説明を表示しています。
jabrena/plinth☆ 4482026年10月13日 更新
Use when you need to add or review Flyway database migrations in a Quarkus application — quarkus-flyway extension, db/migration scripts, quarkus.flyway.* configuration, migrate-at-start, and alignment with JDBC or Panache. This should trigger for requests such as Add or review Flyway migrations in a Quarkus project; Configure quarkus-flyway or db/migration layout; Add versioned Flyway SQL migrations for Quarkus; Review Quarkus database migration ordering; Configure Flyway clean migrate or baselines in Quarkus. Part of Plinth Toolkit
日本語の概要は準備中です。原文の説明を表示しています。
jabrena/plinth☆ 4482026年10月13日 更新
App Store and Google Play screenshot creation with exact platform specs. Covers iOS/Android dimensions, gallery ordering, device mockups, and preview videos. Use for: app store optimization, ASO, app screenshots, app preview, play store listing. Triggers: app store screenshots, aso, app store optimization, play store screenshots, app preview, app listing, ios screenshots, android screenshots, app store images, app mockup, device mockup, app gallery, store listing
日本語の概要は準備中です。原文の説明を表示しています。
aiskillstore/marketplace☆ 4322026年10月13日 更新