「owd」の検索結果

Organizes the evidence and competitive landscape around a drug, target, or pathway by separating disease relevance, tractability, preclinical evidence, clinical evidence, modality fit, and crowding. Always map what is biologically supported, what is druggable, what has actually advanced, and what remains strategically open. Never confuse target relevance with druggability, preclinical activity with clinical promise, or narrative excitement with validated development maturity. Never fabricate references, trial status, approval status, company activity, or asset metadata.

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Maps whether a biomedical research topic, subtopic, or study angle is truly saturated, superficially crowded, strategically occupied, or still open for differentiated entry. Use this skill when a user wants to know whether a hot medical research direction is already overworked, whether meaningful whitespace remains, whether major groups have already occupied the obvious claims, and whether the timing window is still open. Always distinguish popularity from true saturation, and distinguish cosmetic novelty from meaningful differentiating entry.

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Use when constructing or auditing accounting measures for 《会计研究》 (Accounting Research) — discretionary accruals (modified Jones), real earnings management (Roychowdhury), conservatism (Basu / C-Score), comparability, disclosure indices, audit-quality and tax-avoidance proxies — so each measure is built transparently and reproducibly. Use before identification.

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Defines cell populations in flow and spectral cytometry through manual gates (rectangle, polygon, quadrant, boolean) and reproducible automated gating (openCyto gating templates, flowDensity data-driven thresholds, flowClust model-based gates), organized as a hierarchical GatingSet (flowWorkspace) and round-tripped with FlowJo via CytoML. Covers the canonical gate order (time -> debris -> singlets -> live -> lineage), FMO-vs-isotype boundary setting, gate-order dependence and recompute semantics, rare-event/MRD gating, and per-population statistics. Use when building a gating strategy, automating a manual FlowJo scheme across samples, choosing manual vs data-driven gates, or extracting population frequencies.

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Infer gene regulatory networks from bulk or general expression data with mutual-information (ARACNe) and tree-ensemble (GENIE3, GRNBoost2) methods, and infer transcription-factor protein activity from regulons with VIPER and msVIPER. Covers the activity-not-edges paradigm, the undirected-association caveat, the DREAM5 wisdom-of-crowds and method-complementarity result, AUPRC-over-AUROC evaluation, and gold-standard incompleteness. Use when inferring a regulatory network from a bulk expression matrix, finding master regulators, or scoring TF activity from a signature. For single-cell motif-pruned regulons see scenic-regulons; for co-expression modules see coexpression-networks.

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Use when an Unreal Engine 5.8 project misses its frame rate or stutters: "optimize to 60 fps", "we run at 38 fps", CPU or GPU bound, game or render thread too long, hitches, traversal or shader stutter (PSO), GC spikes, camera-cut spikes, Lumen, Nanite, VSM, ray tracing, foliage, crowds or Niagara too expensive, async compute, stat unit, ProfileGPU, Unreal Insights, TraceQuery, snapshothitches, scalability and device profiles, dynamic resolution and TSR, streaming budgets, or proving a fix with before and after captures.

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sechm provides a simple interface between SummarizedExperiment objects and the ComplexHeatmap package. It enables plotting annotated heatmaps from SE objects, with easy access to rowData and colData columns, and implements a number of features to make the generation of heatmaps easier and more flexible. These functionalities used to be part of the SEtools package.

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Privacy-preserving ad measurement with AdAttributionKit (SKAdNetwork's successor) — install and re-engagement attribution, conversion-value strategy under crowd anonymity, and end-to-end postback testing. Use when running paid acquisition beyond Apple Ads, measuring re-engagement campaigns, designing conversion values, or migrating from SKAdNetwork.

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Define and sharpen a brand's market positioning — where it sits relative to competitors, what it owns, and how it differentiates. Use when the user says "brand positioning", "positioning statement", "where do we sit in the market", "how are we different", "differentiation strategy", "positioning map", "competitive positioning", "what space do we own", "brand territory", "we're too similar to competitors", "help me position this brand", or wants to find a defensible place in a crowded category.

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Maps every competitor and the gap they leave. Finds the direct competitors, indirect ones and the substitutes a buyer would use instead, from public sources only, and records what each sells, at what price, how they position themselves and what their customers complain about in public reviews, every fact with a link. Ends with a positioning map and the gap the new business can own. Use when the user says "who are my competitors", "is this market crowded", "what else is out there", "competitor analysis", "find the gap", or "who am I up against".

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Universal QA checklist for generated scientific plots: overlapping labels, clipped text, missing axes/legends, overcrowded data, and cross-journal resolution/format guidance.

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Create original short videos using the 能力见证｜装备特写—连贯表演—人群反应—挑战交接 Creative DNA for MiniMax H3 or Seedance 2.0. Use when the user wants this causal, camera, motion, rhythm, or payoff structure with new subjects and surfaces.

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Build efficient Blender repetition, Array-driven stairs/modules/openings, instancing, scattering, Bezier/NURBS curve-profile geometry, Geometry Nodes fields, repeat zones, simulation zones, particle-like systems, and collective motion. Use for stairs, railings, trim, pipes, cables, repeated windows/panels, vegetation, debris, crowds, rain, snow, modular structures, or any request involving dependent elements or reusable parameters.

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Think and work like an expert Galactic Astronomer. Use when a task calls for Galactic Astronomer judgment. Reasons from distance ladders, dust extinction, and survey selection functions through Gaia DR3 cross-matches, isochrone and Bayesian SFH fitting (PARSEC/MIST, Starfish), and orbit integration in named potentials (McMillan17, MWPotential2015) via galpy, Agama, and Gala, while treating parallax-S/N and RUWE failures, unresolved binaries and fiber collisions, dust-or-crowding overdensities, and spiral-arm-mimicking-streams as first-class failure modes.

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Think and work like an expert Additive Manufacturing Engineer. Use when a task calls for Additive Manufacturing Engineer judgment. Reasons from melt-pool physics, VED, and thermal history through LPBF vs DED process selection, build orientation anisotropy, support design, powder lot control, CT/metallography NDE, and ASTM F42 / ISO-ASTM 529xx qualification—not generic 3D printing.

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Discovery, download, and configuration hub for the entire aelf agent skill ecosystem. Use when the user wants to: (1) explore or list available aelf skills, (2) install/bootstrap aelf skills into Cursor, Claude Desktop, OpenClaw, Codex, or Claude Code, (3) route an aelf-related intent to the correct skill, (4) check health or audit installed skills, (5) onboard a new skill into the aelf ecosystem. Covers domains: Portkey CA wallet, Portkey EOA wallet, Awaken DEX, eForest NFT marketplace, AelfScan explorer, TomorrowDAO governance, aelf node interaction.

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Expert in designing and implementing intelligent game AI systems including behavior trees, finite state machines, GOAP, utility AI, pathfinding, steering behaviors, and perception systems. Specializes in creating believable, performant NPC behaviors that enhance player experience. Use when "game AI, NPC behavior, behavior tree, state machine for game, enemy AI, pathfinding, A* algorithm, navmesh, steering behavior, GOAP, utility AI, AI perception, combat AI, companion AI, boss AI, crowd simulation, flocking, game-ai, behavior-trees, pathfinding, npc, state-machines, goap, utility-ai, steering, perception" mentioned.

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World-class brand positioning expertise combining David Ogilvy's direct response wisdom, Emily Heyward's obsessive brand strategy (Red Antler), and Al Ries/Jack Trout's positioning classics. This skill answers: "What space do we own in the customer's mind, and why does it matter?" Brand isn't what you say about yourself - it's what others say when you're not in the room. Positioning isn't about creativity - it's about claiming territory in an overcrowded mind. Use when "brand positioning, positioning statement, brand strategy, category design, competitive positioning, how should we position, brand differentiation, value proposition, what makes us different, brand platform, brand values, brand personality, brand promise, brand manifesto, tagline, unique selling proposition, usp, category creation, own a word, mind share, brand, positioning, strategy, differentiation, category, competitive, values, identity" mentioned.

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Designing tabletop games - from core mechanics to manufacturing, from prototyping to KickstarterUse when "board game, tabletop, card game, worker placement, deck building, area control, playtesting, rulebook, kickstarter game, game balance, asymmetric factions, euro game, ameritrash, party game, dice game, prototype, game publisher, crowdfunding game, board-games, tabletop, game-design, mechanics, playtesting, kickstarter, manufacturing, rulebook, components, balance, player-interaction" mentioned.

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Design and implement agent-based models (ABM) for simulating complex systems with emergent behavior from individual agent interactions. Use when "agent-based, multi-agent, emergent behavior, swarm simulation, social simulation, crowd modeling, population dynamics, individual-based, " mentioned.

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Use whenever the user wants to find, shortlist, vet, or enrich US cybersecurity firms — pen-testing/red team, security audits, vCISO, SOC 2 readiness, incident response, managed SOC, IAM, cloud security, and AppSec. Triggers on "find me a pen-testing firm for our SOC 2 audit", "shortlist three vCISO services for our healthcare-tech startup", "we need an incident response retainer", or "pull contact info for these 8 security firm domains", even when described indirectly (we got breached, prepare us for the compliance audit, get us SOC 2 ready). Drives the ServiceGraph API (api.servicegraph.co) — a 100k+ US firm catalog filterable by industry, services, location, size, ratings. Skip in-house security hires, "how do I patch CVE-X" or "configure firewall Y" DIY questions, security-product reviews (CrowdStrike vs SentinelOne, etc.), generic security knowledge questions, consumer/personal security advice, non-US firms, individual freelancers and bug-bounty hunters.

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Parse HackerOne / Bugcrowd / Intigriti scope into a structured asset list with in-scope, out-of-scope, and excluded-vuln-class breakdowns. Use when the user has chosen a program and needs to understand exactly what's allowed before recon.

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Evaluate HackerOne / Bugcrowd / Intigriti programs before committing time. Decide signal-to-noise, payout history, response time, scope size, and competition level. Use when the user is considering a new bug bounty target or asking "should I hunt this".

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Improve layout composition, spacing systems, grouping, and visual rhythm. Use when the user mentions weak layout structure, arbitrary spacing, weak grouping, crowded composition, or layout monotony rather than priority/emphasis problems.

日本語の概要は準備中です。原文の説明を表示しています。