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configuring-experiment-rollout

無料

Configures the rollout shape of a PostHog experiment — the variant split (50/50, 80/20, A/B/C ratios), the overall rollout percentage that gates how many users enter the experiment, and the disambiguation when a percentage like "roll out to 25%" could mean either. Use when the user mentions a rollout percentage, variant split, or traffic distribution; gives a ratio like 60/40, 70/30, or 80/20; asks "who sees the test variant?"; wants to increase, decrease, or change the rollout or split on a draft or running experiment; weighs equal vs uneven splits; or proposes a mid-experiment split change (often an anti-pattern that needs reset or end-and-restart).

日本語の概要は準備中です。原文の説明を表示しています。

0xAidan/polymarket-bot-test42026年9月4日更新

bio-outlier-splicing-detection

無料

Detects aberrant splicing in single rare-disease patients vs a control panel using FRASER 2.0 (Bioconductor; Beta-binomial autoencoder on Intron Jaccard Index, default delta cutoff 0.1, q hyperparameter), OUTRIDER (gene-level outlier expression via autoencoder denoising), LeafcutterMD (Dirichlet-multinomial outlier mode of LeafCutter for annotation-free junctions), and DROP (Snakemake pipeline integrating FRASER2 + OUTRIDER + monoallelic expression for clinical diagnostics). The statistical model is fundamentally different from differential splicing — single-sample-vs-cohort outlier detection rather than two-group comparison. Standard tool in EU rare-disease (Solve-RD) and NIH UDN programs. Use when applying RNA-seq to undiagnosed Mendelian disease, validating predicted splice variants in clinical samples, or detecting cryptic splicing in disease tissue.

日本語の概要は準備中です。原文の説明を表示しています。

peacezha/TRACE32026年10月11日更新

bio-single-cell-splicing

無料

Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1 junction read per cell per AS event). Plate-based full-length methods (Smart-seq3, FLASH-seq, VASA-seq, STORM-seq) and single-cell long-read (MAS-Iso-seq, scISOr-Seq2) are the chemistries that give per-cell isoform structure. Tools include MARVEL (R, Smart-seq integrated), BRIE2 (Bayesian PSI with regulatory features and ELBO_gain test), scQuint (junction-cluster, plate-based; not for 10X), SpliZ (annotation-free Z-score), Psix (graph-smoothness regulated AS), and Sierra (alternative polyadenylation, often confused with AS). Use when analyzing isoform usage in scRNA-seq, identifying cell-type-specific splicing, or determining whether scRNA-seq chemistry supports splicing analysis at all.

日本語の概要は準備中です。原文の説明を表示しています。

peacezha/TRACE32026年10月11日更新

section-read-split

無料

Introduce the cross-section read interface boundary (I<Section>ServiceRead) for one section's service per memory/architecture/section-read-write-split.md. Audits the surface, evaluates which methods belong on the read interface, sets up the workspace, dispatches a subagent that introduces the interface and migrates non-section callers, opens a PR. Use when the user says 'read split for X', 'split <Section>Service', 'add I<Section>ServiceRead boundary', 'apply the section-read-write-split rule to <Section>', or any variation of carving the cross-section read surface out of a section's full service interface. Reference implementation is Teams (PR 678). Operates on one section per invocation.

日本語の概要は準備中です。原文の説明を表示しています。

nobodies-collective/Humans32026年10月7日更新

bio-single-cell-splicing

無料

Analyzes alternative splicing at single-cell resolution. The first decision is library chemistry — 10X 3' is fundamentally limited (RT primes from poly-A, R2 falls in 3' UTR, <0.1 junction read per cell per AS event). Plate-based full-length methods (Smart-seq3, FLASH-seq, VASA-seq, STORM-seq) and single-cell long-read (MAS-Iso-seq, scISOr-Seq2) are the chemistries that give per-cell isoform structure. Tools include MARVEL (R, Smart-seq integrated), BRIE2 (Bayesian PSI with regulatory features and ELBO_gain test), scQuint (junction-cluster, plate-based; not for 10X), SpliZ (annotation-free Z-score), Psix (graph-smoothness regulated AS), and Sierra (alternative polyadenylation, often confused with AS). Use when analyzing isoform usage in scRNA-seq, identifying cell-type-specific splicing, or determining whether scRNA-seq chemistry supports splicing analysis at all.

日本語の概要は準備中です。原文の説明を表示しています。

peacezha/HPClaw32026年10月11日更新

bio-outlier-splicing-detection

無料

Detects aberrant splicing in single rare-disease patients vs a control panel using FRASER 2.0 (Bioconductor; Beta-binomial autoencoder on Intron Jaccard Index, default delta cutoff 0.1, q hyperparameter), OUTRIDER (gene-level outlier expression via autoencoder denoising), LeafcutterMD (Dirichlet-multinomial outlier mode of LeafCutter for annotation-free junctions), and DROP (Snakemake pipeline integrating FRASER2 + OUTRIDER + monoallelic expression for clinical diagnostics). The statistical model is fundamentally different from differential splicing — single-sample-vs-cohort outlier detection rather than two-group comparison. Standard tool in EU rare-disease (Solve-RD) and NIH UDN programs. Use when applying RNA-seq to undiagnosed Mendelian disease, validating predicted splice variants in clinical samples, or detecting cryptic splicing in disease tissue.

日本語の概要は準備中です。原文の説明を表示しています。

peacezha/HPClaw32026年10月11日更新

find-CEngineClient_IsPlayingDemo

無料

Agent fallback for CEngineClient_IsPlayingDemo (auto-generated, category: func). Locate CEngineClient_IsPlayingDemo in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineClient_IsPlayingDemo, CEngineClient_IsPlayingDemo

日本語の概要は準備中です。原文の説明を表示しています。