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概要と使いどころ
Advanced Biopython modules for motifs, population genetics, sequence utilities, restriction analysis, clustering, and GenomeDiagram visualization; use when you need extended bioinformatics analysis beyond basic sequence I/O and alignment.
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Simulate structured grant peer review for biomedical proposals; use when stress-testing significance, innovation, approach, feasibility, and reviewer-facing weaknesses before submission.
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Designs a translational blueprint for moving a biomedical finding toward diagnosis, prognosis, treatment response prediction, patient stratification, or therapeutic development, with explicit translational milestones, validation thresholds, and feasibility-sensitive route framing.
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Designs primary, secondary, and exploratory endpoints for biomedical and clinical research protocols. Always use this skill when a user needs to translate study aims into operational endpoint definitions with event rules, assessment timing, composite logic, interpretability, and protocol-stage auditability. Focus on endpoint precision, feasibility, clinical meaning, ambiguity reduction, and implementation readiness rather than generic study design advice.
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Plans sample size estimation logic, power assumptions, feasibility checks, and fallback enrollment strategies for clinical and translational study protocols.
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A medical-research-native literature reading skill for users with clinical, bioinformatics, translational, and basic experimental backgrounds. Use this skill whenever a user wants to read, analyze, critique, or interpret a medical or scientific paper — whether they provide a PDF, abstract, DOI, PMID, or just a title. Triggers include requests like \"analyze this paper\", \"critique this study\", \"is this a strong paper?\", \"give me similar studies\", \"prepare me for journal club\", \"help me understand this bioinformatics paper\", \"what are the weaknesses here?\", or \"turn this into a mind map\". Also activate for any downstream deliverables such as journal club kits, comparison tables, PI decision briefs, replication starters, or follow-up experiment designs. Do NOT treat as a generic summarizer — this skill performs structured evidence-type classification, track-specific critical appraisal, interpretation-boundary judgment, and research-grade follow-up generation.
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Designs cell-based and animal-based validation plans that translate computational, omics, biomarker, genetic, or clinical findings into experimentally testable validation routes. Always use this skill whenever a user wants to move from an in silico, statistical, or clinical association finding toward wet-lab validation using cell systems, organoid-like systems, xenograft or genetically relevant animal models. It should define the exact claim to test, separate mechanism-testing from association-support and translational-support goals, choose the best-fit model family, specify perturbation strategy, readouts, controls, sequencing of experiments, and four workload configurations (Lite / Standard / Advanced / Publication+) with one recommended primary plan. Never fabricate model availability, reagent availability, species relevance, assay feasibility, phenotype penetrance, expected effect sizes, validation success, or literature references.
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Core building blocks of Suricata signatures and multi-condition DPI logic
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ObsPy allows you to easily download earthquake data from various data centers/networks through its client API. This is an overview of available services and a demo of the client API for International Federation of Digital Seismograph Networks (FDSN). Use this if you need to download earthquake research data.
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Reference guide for translating Python syntax constructs to Scala equivalents. Use when converting Python code to Scala and need mappings for basic syntax elements like variable declarations, control flow, comprehensions, string formatting, and common operators.
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Cut, trim, concatenate, and split video files - basic video editing operations
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Deterministic handbook-grounded retrieval and thermocouple computations for reflow profile compliance outputs such as ramp, TAL, peak, feasibility, and selection.
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Operational workflow for hard integer-programming optimization tasks: selecting an installed solver, preserving solver/incumbent certificates, extracting feasible schedules, recomputing metrics from final outputs, and writing consistent reports. Use when a task requires a MIP, solver status, objective value, bound, gap, formulation write-up, or benchmark output files.
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Use for day-ahead or multi-period unit commitment problems, including thermal on/off schedules, dispatch, startup/shutdown logic, minimum up/down time, ramping, spinning reserve deliverability, renewable curtailment, operating-cost accounting, and independent feasibility checks for power-system operations schedules.
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Comprehensive verification checklists for MCP Apps. Tests with basic-host reference, validates handler-before-connect, text fallback, resource URI linking, single-file bundling, host styling, CSP, and legacy pattern detection.
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Adversarial plan review by 3 independent reviewers (Feasibility, Completeness, Scope & Alignment) before presenting to user.
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Use when adding metadata to commits without changing history, tracking review status, test results, code quality annotations, or supplementing commit messages post-hoc - provides git notes commands and patterns for attaching non-invasive metadata to Git objects.
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Master advanced Git workflows including rebasing, cherry-picking, bisect, worktrees, and reflog to maintain clean history and recover from any situation. Use when managing complex Git histories, collaborating on feature branches, or troubleshooting repository issues.
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Transform data into compelling narratives using visualization, context, and persuasive structure. Use when presenting analytics to stakeholders, creating data reports, or building executive presentations.
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Enforce the replication-protocol.md rule by cross-checking numeric claims in a manuscript against the actual R / Stata / Python outputs. Report PASS/FAIL per claim against tolerance thresholds. Use before submission and before releasing a replication package.
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Snapshot the computational environment for a replication package — detects the analysis stack (R / Stata / Python) and emits the right lockfiles (renv.lock + sessionInfo.txt, requirements.txt / environment.yml / uv.lock, Stata version + ado package list), records seeds and RNG kind, optionally writes a pinning Dockerfile, and produces a paste-ready "Computational requirements" block. Use when user says "capture the environment", "snapshot my dependencies", "pin the versions", "make a renv.lock / requirements.txt", "make this byte-reproducible", or before releasing a replication package to openICPSR / the AEA Data Editor.
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AI DevKit · Analyze and simplify existing implementations to reduce complexity, improve maintainability, and enhance scalability. Use when users ask to simplify code, reduce complexity, refactor for readability, clean up implementations, improve maintainability, reduce technical debt, or make code easier to understand.
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Creates and retrieves AI video and image-related assets via the Arcads external API (Seedance 2.0, Sora 2, Veo 3.1, Kling, Grok Video, Nano Banana, b-roll, scene, script/actor flows). Loads prompts from the bundled prompting guide and model library, respects HTTP Basic auth from ARCADS_API_KEY, and polls assets/videos until ready. Use when the user mentions Arcads, external-api.arcads.ai, Seedance, Sora2, Veo, Kling, Nano Banana, b-roll, UGC scripts, or generating marketing creative through Arcads.
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Apply IRQL graph functions to KQL or IRQL query results for Kusto Explorer visualization. Generates Lift_To_Graph mappings and composes Graph_Render_View, Graph_Fold_By_Property, Extract_Node_*, Enrich_Node_*, and Enrich_Graph_* calls. Accepts a supplied query or limited basic natural-language source request; it is not a general natural-language-to-KQL/IRQL skill. WHEN: Lift_To_Graph, Graph_Render_View, Graph_Fold_By_Property, IRQL graph enrichment, graph mapping for existing query results, icon-decorated graph, fold graph nodes. Use azure-kusto-graph for native make-graph analysis, graph-match, shortest paths, components, or persistent graphs.
日本語の概要は準備中です。原文の説明を表示しています。