「core」の検索結果

Generate the success criteria for a task or question, then review work against them. Given a task, goal, or open-ended question, decompose it into scenarios, evaluation perspectives, and fine-grained weighted YES/NO criteria using the Recursive Expansion Tree (RET) method; if work is supplied, score it criterion-by-criterion and surface what is missing or could be better. Use when asked to self-review or check your own work, judge whether a task is done well or completely, build a definition-of-done or completeness checklist, create an evaluation rubric or grading criteria, score or grade answers to a question, set up an LLM-as-judge rubric, or when the user mentions self-review, completeness check, success criteria, evaluation criteria, scoring rubric, Qworld, or the RET algorithm.

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Drug-combination synergy analysis — quantify whether two drugs together are synergistic, additive, or antagonistic using the standard reference models (Bliss independence, HSA / highest single agent, Loewe additivity, ZIP, and the Chou-Talalay Combination Index). Use when you have measured single-drug and combination effects (inhibition/viability) and need a synergy score. Explains which model to use, what data each one needs, and how to read the score. NOT for looking up pre-computed synergy in a database (use the SYNERGxDB tool / cell-line-profiling skill).

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Quantitative drug-target validation pipeline. Scores druggability, selectivity, safety profile, ADMET feasibility, and structural tractability with a composite Target Validation Score (0-100) and GO/NO-GO recommendation. Use for go/no-go decisions on a target before commit-to-medchem, target prioritization across a list, and target-deselection rationale.

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Build AI lead scoring systems. TRIGGERS - Use when user needs help with ai-lead-scorer related tasks.

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Automated WCAG 2.1 AA accessibility testing with axe-core and Lighthouse CI. Auto-detects frontend framework (React, Next.js, Vue, Angular, Svelte, Astro, Flutter, React Native), discovers all routes and interactive components, installs Playwright + axe-core for page-level scanning and jest-axe/vitest-axe for component-level testing. Generates tests for color contrast (4.5:1), alt text, form labels, ARIA attributes, heading order, landmark regions, focus visibility, keyboard navigation (tab order, focus traps, modal focus management, skip-to-content), screen reader compatibility (aria-live regions, error announcements, toast notifications), and Flutter Semantics validation (48dp touch targets, semanticLabel). Reports violations by severity (critical, serious, moderate, minor) with WCAG criterion references. Use when adding a11y testing, auditing accessibility compliance, fixing contrast issues, or validating keyboard and screen reader support.

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Use when building or reviewing core Quarkus applications with CDI beans and scopes, SmallRye Config and profiles, lifecycle, interceptors and events, virtual threads, and test-friendly design. This should trigger for requests such as Review Java code for Quarkus application structure and CDI; Apply best practices for Quarkus configuration and beans; Improve CDI interceptors, events, or programmatic injection in Quarkus; Add virtual-thread configuration or tune CDI lifecycle. Part of cursor-rules-java project

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Accessibility testing for web applications using Playwright (@playwright/test) with TypeScript and axe-core. Use when asked to write, run, or debug automated accessibility checks, keyboard navigation tests, focus management, ARIA/semantic validations, screen reader compatibility, or WCAG 2.1 Level AA compliance testing. Covers axe-core integration, POUR principles (perceivable, operable, understandable, robust), color contrast, form labels, landmarks, and accessible names.

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Technical SEO audit across 8 categories: crawlability, indexability, security, URL structure, mobile, Core Web Vitals, structured data, JS rendering. Schema deep validation → seo-schema. AI crawlers → seo-geo-technical. Use when user says "technical SEO", "crawl issues", "robots.txt", "Core Web Vitals".

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Windows アプリ開発 (Windows App SDK / WinRT) のファイル・設定・データ保存リファレンス。 Windows.Storage の StorageFile, StorageFolder, IStorageItem, FileIO, PathIO, CachedFileManager, DataReader, DataWriter, BasicProperties。ApplicationData, ApplicationDataContainer, ApplicationDataCompositeValue のローカル・ローミング設定。 FileOpenPicker, FileSavePicker, FolderPicker, KnownFolders, StorageApplicationPermissions (FutureAccessList / MostRecentlyUsedList)。 JsonObject, JsonArray, XmlDocument, SQLite, EF Core, Microsoft.Data.SqlClient (SQL Server), Cosmos DB, MySQL, MongoDB 接続。

Theatre.js アニメーションツールキットリファレンス。 @theatre/core / @theatre/studio / @theatre/r3f / @theatre/dataverse。 getProject, Sheet, Sequence, Object, val, onChange, prop-types（number / rgba / compound / image）。 studio initialize / extend / transaction / scrub / createPane。 SheetProvider, editable, useCurrentSheet, useVal, usePrism, useAtom。 keyframe アニメーション、audio sync、state JSON、React Three Fiber 統合。

Windows アプリ開発 (DirectX / WinRT メディア) のグラフィックス・メディア API リファレンス。 Direct2D (ID2D1Factory, ID2D1DeviceContext, ID2D1Bitmap1, ID2D1Effect, D2D1 Effects, ID2D1PathGeometry), DirectWrite (IDWriteFactory, IDWriteTextLayout, DWriteCore), Direct3D 11/12 (D3D11CreateDevice, D3D11On12, DXGI SwapChain, HLSL, D3D12 PipelineState, D3D12 DRED), Microsoft.UI.Composition (Compositor, Visual, ExpressionAnimation, InteractionTracker, MicaController), カメラ・画面キャプチャ (MediaCapture, MediaFrameReader, GraphicsCaptureSession, Windows Studio Effects, OpenCV)、音声・動画再生 (MediaPlayer, MediaPlaybackSession, AudioGraph, MediaTranscoder, AdaptiveMediaSource, HLS, DASH, CastingDevicePicker, AudioPlaybackConnection)。

Rust 製フロントエンドフレームワーク fandhe-frontend のリファレンス。 SSR / SPA / SSG / View Transitions、hydration、単一実行ファイル配布、Vercel デプロイ、既定エスケープ。 クレート core / app / interactive / server(generate_pages) / headless-ui(Primitives) / pre-styled-ui(Themes, motion feature) / wireframe-ui(Wireframes) / animation(fandhe-animation, data-* 属性) / wasm-full(feature 選択)。 Blocks(Hero / Pricing / Cart 等セクション例 329 件)。CLI fw。

Rust 製バックエンド HTTP サーバーフレームワーク fandhe-backend のリファレンス。 fandhe-backend-core / -http / -routes。Server, BoundServer, Router（merge）, Handler。 4 拡張点 Middleware（on_response_with_status）/ UpgradeHandler / RequestGate / Interceptor。 Diagnostics, StreamingResponse, sans-IO HTTP/1.1, graceful shutdown。 プラグイン cors, websocket（WsSender）, graphql, openapi, webrtc 等。

Rust 製 AI/ML ライブラリ fandhe-ai のリファレンス。Burn / candle / tch 非依存の from-scratch 実装。 compat::Sequential, compat::array, tape(), tape_for(), Tape, Var, Tensor, Gradients, LinearVars, Device (Cpu / Cuda / Metal)。 tensor-core の kernel fusion, FusionPlan, BackendOps。dynamic-tape autodiff。 cfg ベースのバックエンド構成・数値一致契約。ONNX / safetensors 相互運用。 guardrail / self-repair CLI。

mssql (node-mssql, Node.js 向け Microsoft SQL Server クライアント) の API リファレンス。 tedious / msnodesqlv8 ドライバー、SQL Server / T-SQL / TDS 接続、ConnectionPool、 `sql.query` タグ付きテンプレート、bulk insert、Table-Valued Parameter (TVP)、 prepared statement、isolation level、Diagnostics Channel、Azure AD 認証、CLI。 Drizzle ORM 経由の SQL Server 利用 (drizzle-orm/mssql-core) は別スキル drizzle が対象。

NVIDIA CUDA GPU 並列コンピューティングリファレンス。 CUDA C++ / CUDA Python, kernel, nvcc, Unified Memory, CUDA Graphs, Cooperative Groups, Driver API, マルチ GPU。 PTX ISA 命令セット, state space, MMA 命令。 Blackwell チューニング, Streaming Multiprocessor, NVLink。 CUTLASS / CuTe DSL / CuTe C++ GEMM, Tensor Core, tcgen05, Operator API, nsight-compute, compute-sanitizer。

OpenAI API (developers.openai.com) の運用・管理リファレンス。 Administration API, admin API keys, RBAC, roles, groups, invites, projects, spend limits, audit logs, usage / costs API, Terraform provider (openai/openai), workload identity federation (WIF, OIDC/SPIFFE), safety best practices, moderation API, production best practices, deployment checklist, cost / latency optimization, fast mode, Realtime API costs。rate limits・error handling・prompt caching は openai-api-core、Codex のワークスペース 管理は openai-codex が担当。

TanStack Virtual (React 仮想スクロール、@tanstack/react-virtual) の API リファレンス。 useVirtualizer, useWindowVirtualizer, Virtualizer, VirtualItem, estimateSize, measureElement, rangeExtractor, overscan, lanes, getVirtualItems, getTotalSize, scrollToIndex。固定/可変/動的計測、grid、sticky header、infinite scroll、table、 window scroll 仮想化。別名 react-virtual, virtual-core。 react-flow / Compose LazyColumn / WinUI ListView とは別（DOM 向けヘッドレス仮想化）。

Apple データ永続化・データフロー・ネットワーク・ユーティリティリファレンス。 SwiftData / Core Data / Foundation / Combine。 @Model、ModelContainer、ModelContext、@Query、Predicate、FetchDescriptor、 NSManagedObject、NSFetchRequest、NSPersistentContainer、NSFetchedResultsController、 URLSession、JSONEncoder、JSONDecoder、Publisher、@Published、AnyCancellable、sink。

AMD ROCm / HIP GPU コンピューティングリファレンス。 hipMalloc, hipLaunchKernelGGL, HIP Graph, HIPRTC, hipify, rocBLAS, MIOpen, RCCL, rocprofv3, amd-smi, rocminfo, CDNA1-4 / RDNA1-4, MI300 / MI350, gfx942, Matrix Core, wave32/64。

Apple アプリサービスリファレンス。StoreKit 2、CloudKit、WidgetKit、ActivityKit、 User Notifications、Core Location、MapKit、HealthKit、Sign in with Apple。 Product, Transaction, CKRecord, Widget, TimelineProvider, CLLocationManager, Map, HKHealthStore, ASAuthorizationController, UNUserNotificationCenter。

スコアリング / ML のドメイン正しさのレビュー。SCORE_WEIGHTS の単一定義と合計1.0・ドキュメント追随、スコアリングと ML の10要素の一致（手書きで並ぶ全箇所の同時更新）、未来情報リーク（as-of カットオフを通していない取得経路の新設）、値域0〜100とゼロ除算、データ欠損時の既定値、学習・予測の決定性と再現性、JRA 枠番割当規則、バックテスト指標（1位的中率・上位3頭精度・順位相関・ROI）の計算を検証。Use when user says 'スコアリングレビュー', 'review scoring', 'ML レビュー', 'スコア計算チェック', '特徴量チェック', or 'バックテスト検証'.

Gate a build on browser fingerprint regressions with liarjs - save a baseline scan as JSON, diff later runs against it, and fail the job when the consistency score falls below a floor. Use when asked to add a fingerprint or headless-detection check to GitHub Actions, GitLab CI or another pipeline, to catch a regression in a Chromium build or scraping harness before it ships, or to track how a fingerprint score changes across commits.

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Analyzes pooled CRISPR screens with MAGeCK (Li et al 2014), covering count generation (mageck count), the RRA two-condition workflow (mageck test using alpha-RRA over per-sgRNA negative-binomial p-values), the MLE multi-condition workflow (mageck mle with explicit design matrix and beta-score output), normalization choice (median vs total vs control-sgRNA vs spike-in), sgRNA efficiency injection, paired-sample testing, time-course design, drug-screen versus dropout-screen design matrices, MAGeCKFlute and MAGeCK-VISPR downstream visualization, and decision logic for when to use MAGeCK vs JACKS / BAGEL2 / drugZ / Chronos. Use when running a fresh CRISPR screen analysis, picking RRA vs MLE for the experimental design, choosing a normalization method from QC signatures, debugging MLE convergence failure or NaN beta scores, comparing MAGeCK output across tools, or building a batch-aware multi-cell-line / multi-condition MLE design matrix.

日本語の概要は準備中です。原文の説明を表示しています。