「impact」の検索結果

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

First-principles assumption auditor. Classifies each hidden assumption (fact / convention / belief / interest-driven), ranks by fragility × impact, and rebuilds conclusions from verified premises. Bilingual: auto-detects Chinese or English.

日本語の概要は準備中です。原文の説明を表示しています。

Select traceable regression coverage from change impact, affected risks, criteria, dependencies, and prior defects rather than execution convenience.

日本語の概要は準備中です。原文の説明を表示しています。

Build an impact-based regression selection with explicit traceability, inclusions, exclusions, and limitations.

日本語の概要は準備中です。原文の説明を表示しています。

Explain Ponytail's intended tradeoffs and measurement boundary. It does not estimate code, cost, or speed savings for the current repository. One-shot display, not a persistent mode. Trigger: ponytail-gain, "ponytail gain", "what does ponytail save", "show ponytail impact", or "ponytail scoreboard".

日本語の概要は準備中です。原文の説明を表示しています。

ATM 版本升級與開源 release train 工作流。USE FOR: ATM frameworkVersion 升級、release impact 分類、SemVer 決策、CODEOWNERS / changeset / release gate 檢查、ATM upstream release docs 維護。

日本語の概要は準備中です。原文の説明を表示しています。

Apply one logical code change with mandatory impact mapping, git snapshot, verification, and automatic revert on failure. Load when the user asks for a safe edit, verified change, one change at a time with rollback, or codespine-style edit loop. Also triggers on "safe change", "edit with verification", "don't break the build", "revert if tests fail", or any non-trivial code edit where blast radius matters. Always runs dependency-mapping first. Pairs with incremental-implementation for multi-slice work; this skill is one atomic verify cycle per invocation.

日本語の概要は準備中です。原文の説明を表示しています。

Map symbol dependencies, callers, and blast radius before editing code. Load when the user asks what depends on a symbol, what breaks if they change something, blast radius of a change, reverse dependencies, or which tests cover a function. Also triggers on "who calls this", "impact of changing", "dependency map", "what uses this", "find callers", or before any non-trivial edit when safe-change is not yet active. Pairs with codebase-understanding for broad architecture; this skill is symbol-scoped and edit-gated.

日本語の概要は準備中です。原文の説明を表示しています。

You bring the third dimension to the web. You know when 3D enhances and when it's just showing off. You balance visual impact with performance. You make 3D accessible to users who've never touched a 3D app. You create moments of wonder without sacrificing usability.

日本語の概要は準備中です。原文の説明を表示しています。

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to understand which MVR violations disqualify a driver under federal rules. Covers § 391.15 disqualifications, varying state rules, and CSA impact.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a carrier asks whether to buy or lease their next tractor (or trailer), comparing full-service lease (Ryder, Penske, NationaLease), capital lease, finance lease, walk-away open-end lease, or cash purchase. Covers tax treatment, residual risk, maintenance bundling, balance-sheet impact, and cash-flow modeling.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when a driver receives an out-of-service (OOS) violation. Covers the immediate compliance, paperwork retention, and CSA impact.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about driver fatigue management — circadian rhythm impact on driving, recognizing fatigue, fatigue risk management programs (FRMS), night driving safety, microsleep recognition, drowsiness detection technology, and how HOS rules relate to actual fatigue (and why 11-hour driving is risky even when legal). Reference FMCSA Fatigue Management research.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a carrier asks about autonomous trucks — current state of Level 4 development, major programs (Aurora, Kodiak, Plus, Waymo Via, Embark history), regulatory status, operational implications, hub-to-hub model, driver impact, insurance, and what carriers should be doing now (or not doing) to prepare.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "このファイルを変えたら何が壊れる？", "what depends on this function", "影響範囲を調べて", "show me what imports this module", or wants to understand the blast radius before modifying a shared utility, exported type, or public API. Traces import/require references up to two levels deep and lists affected test files.

Analyze an idea, proposal, change, claim, or decision from facts through problem, value, mechanism, consequences, evidence, alternatives, and action. Use when the user asks what something is for, why it matters, whether it is worth doing, what impact it has, or how to decide. Do not use for simple factual lookup or straightforward execution.

日本語の概要は準備中です。原文の説明を表示しています。

Complete workflow for dynamic analysis. Use when user mentions impact, crash, drop test, transient, or time-varying response. Handles explicit and implicit dynamics.

日本語の概要は準備中です。原文の説明を表示しています。

Comprehensive China A-share stock analysis covering fundamental analysis, technical analysis, policy impact assessment, and market-specific features (T+1 trading, price limits, northbound capital flow). Use when user asks about A股分析, Chinese mainland stocks, Shanghai/Shenzhen listed stocks, or needs analysis considering China market characteristics.

日本語の概要は準備中です。原文の説明を表示しています。

First-principles assumption auditor. Classifies each hidden assumption (fact / convention / belief / interest-driven), ranks by fragility × impact, and rebuilds conclusions from verified premises. Bilingual: auto-detects Chinese or English.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze blast radius before making code changes

日本語の概要は準備中です。原文の説明を表示しています。

Autonomous rule adherence checker. Scans the codebase for rule violations, fixes the highest-impact ones in an isolated worktree, runs full validation, creates a PR. Uses memory to track progress across runs.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user wants to know what will break if they change something, or needs safety analysis before editing code. Examples: "Is it safe to change X?", "What depends on this?", "What will break?"

日本語の概要は準備中です。原文の説明を表示しています。

Review only changes since last commit using impact analysis. Token-efficient delta review with automatic blast-radius detection.

日本語の概要は準備中です。原文の説明を表示しています。