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概要と使いどころ
Write modern, high-performance C# code using records, pattern matching, value objects, async/await, Span<T>/Memory<T>, and best-practice API design patterns. Emphasizes functional-style programming with C# 12+ features.
日本語の概要は準備中です。原文の説明を表示しています。
Profiles a genome from raw reads BEFORE assembly with a k-mer spectrum (KMC or Jellyfish histogram), then models it with GenomeScope2 to estimate genome size, heterozygosity, repeat content, and ploidy, and Smudgeplot to infer ploidy from heterozygous k-mer pairs (diploid AB vs triploid AAB vs tetraploid AABB). Covers choosing k via Merqury best_k.sh, the k-mer-coverage vs sequencing-coverage confusion, reading het/repeat/contamination/organelle peaks, why noisy ONT must not be used for counting, and how the estimate becomes the NG50 denominator, the Flye -g value, the hifiasm --hom-cov/purge setting, and the 1.5-2x-too-big haplotig sanity check. Use when starting any de novo assembly, deciding whether short reads can work, estimating genome size for an unknown organism, diagnosing ploidy, or sanity-checking an assembly's size against expectation.
日本語の概要は準備中です。原文の説明を表示しています。
Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.
日本語の概要は準備中です。原文の説明を表示しています。
Call copy number variants with the GATK best-practices workflows — the somatic CNV pipeline (CollectReadCounts, DenoiseReadCounts with tangent normalization, ModelSegments, CallCopyRatioSegments) and the germline GATK-gCNV pipeline (DetermineGermlineContigPloidy, GermlineCNVCaller cohort/case mode, PostprocessGermlineCNVCalls). Covers panel-of-normals construction, AnnotateIntervals/FilterIntervals, allelic-count integration, and QS-based filtering. Use when integrating CNV calling into a GATK variant pipeline, calling rare germline CNVs from an exome cohort, deciding between the somatic and germline GATK workflows, or diagnosing why tangent normalization removed a real event or why gCNV output has low precision.
日本語の概要は準備中です。原文の説明を表示しています。
Volcengine official documentation lookup helper. Supports both document search and full-content fetch across Volcengine products, developer tools, support content, best practices, pricing, deployment, troubleshooting, API, SDK, and policy pages.
日本語の概要は準備中です。原文の説明を表示しています。
React Native and Expo best practices for building performant mobile apps. Use when building React Native components, optimizing list performance, implementing animations, or working with native modules. Triggers on tasks involving React Native, Expo, mobile performance, or native platform APIs.
日本語の概要は準備中です。原文の説明を表示しています。
Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against best practices".
日本語の概要は準備中です。原文の説明を表示しています。
React and Next.js performance optimization guidelines from Vercel Engineering. This skill should be used when writing, reviewing, or refactoring React/Next.js code to ensure optimal performance patterns. Triggers on tasks involving React components, Next.js pages, data fetching, bundle optimization, or performance improvements.
日本語の概要は準備中です。原文の説明を表示しています。
Guides the agent to reference official MathWorks Documentation and Help. Determine correct function syntax and workflows from user guides when deeper context is needed. Minimize iterations and repetitive trial and error. Use this skill to: Identify correct syntax and configuration details. Retrieve relevant, version-specific (or release-specific) information from official documentation. Consult user guides when conceptual or workflow context is needed. Apply best practices.
日本語の概要は準備中です。原文の説明を表示しています。
Use when engineering or selecting the best features for single-response classification or regression in MATLAB, whatever the data's modality — for non-tabular data it routes extraction to a domain skill, then selects, assesses, and delivers on the resulting table. Not for multi-response problems, model training, or raw data acquisition.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill to classify tabular data end-to-end in MATLAB — load a dataset, prepare and clean it, select promising classifiers, train them, and compare accuracies with cross-validation, holdout, or hyperparameter optimization plus statistical tests. TRIGGER when: user asks to classify tabular data, pick classifiers for a dataset, compare classifier accuracy, run cross-validation or a holdout evaluation, or find the best model with statistical uncertainty. DO NOT TRIGGER when: user has non-tabular inputs (images, sequences, time series), wants a regression model, is training a specific neural network architecture (use matlab-train-network), or wants cost-sensitive learning or an arbitrary class-prior vector (this skill only supports the built-in uniform-prior toggle for imbalanced data).
日本語の概要は準備中です。原文の説明を表示しています。
Manage IAM users, roles, and policies. Implement least-privilege access and security best practices. Use when configuring AWS identity and access management.
日本語の概要は準備中です。原文の説明を表示しています。
Provision AWS infrastructure with Terraform. Create modules, manage state, and implement IaC best practices. Use when deploying AWS resources declaratively.
日本語の概要は準備中です。原文の説明を表示しています。
Adversarial senior review of the spec before any code is written. Constructs a skeptical reviewer whose authority comes from the codebase, §R research, and live best-practice — then tries to REFUTE the spec, not rubber-stamp it. Every finding cites evidence (file:line or source); unverifiable ones are flagged. Survivors harden §V; the run ends in an explicit go / no-go gate. Triggers before building anything high-blast-radius, when the user says "review the spec", "red-team this", "is this plan sound", "senior review", or invokes /ck:review.
日本語の概要は準備中です。原文の説明を表示しています。
Optimize e-commerce checkout flow to reduce cart abandonment. Friction analysis, payment method optimization, trust signals, and checkout UX best practices.
日本語の概要は準備中です。原文の説明を表示しています。
Competitor research — pricing comparison, bestseller analysis, differentiation strategy
日本語の概要は準備中です。原文の説明を表示しています。
CloudBase platform overview and routing guide. This skill should be used when users need high-level capability selection, platform concepts, console navigation, realtime (broadcast / presence / live database changes), or cross-platform best practices before choosing a more specific implementation skill.
日本語の概要は準備中です。原文の説明を表示しています。
CloudBase PostgreSQL access-pattern and slow-query quality guidance. Use when designing how tables are read and written, eliminating per-row database calls, adding indexes for filters or joins, reviewing high-traffic data access, or explaining a slow SQL query. Not for first-time PG SDK setup, login UI, or NoSQL collections.
日本語の概要は準備中です。原文の説明を表示しています。
Complete guide for CloudBase cloud storage using Web SDK (@cloudbase/js-sdk) - upload, download, temporary URLs, file management, and best practices.
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Review code for quality, security, and best practices. Use when the user asks for code review, wants feedback on their code, mentions reviewing changes, or asks about code quality.
日本語の概要は準備中です。原文の説明を表示しています。
Review Python code for quality, security, and best practices
日本語の概要は準備中です。原文の説明を表示しています。
Best practices for creating research diagrams with Excalidraw MCP tools
日本語の概要は準備中です。原文の説明を表示しています。
Best practices for systematic research, source evaluation, and evidence gathering
日本語の概要は準備中です。原文の説明を表示しています。
Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against best practices".
日本語の概要は準備中です。原文の説明を表示しています。