「bloc」の検索結果

Designs donor/repair templates for precise CRISPR knock-ins -- choosing the format (ssODN, long-ssDNA/Easi-CRISPR, dsDNA/plasmid, AAV6), sizing homology arms, placing the cut within ~10 bp of the edit, and adding a mandatory codon-checked blocking (PAM/seed) mutation so the edited allele is not re-cut. Frames the HDR-vs-NHEJ-vs-MMEJ pathway competition, the MMEJ (PITCh) and homology-independent (HITI/HMEJ) alternatives for post-mitotic cells, ssODN strand/asymmetry choice, phosphorothioate end-protection, and ranked HDR enhancers. Use when designing a donor for a point mutation, epitope/fluorophore tag, allele replacement, or knock-in, or when HDR efficiency is low. Guide design and base/prime editing are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Handles BED-format genomic intervals (BED3 through BED12, narrowPeak/broadPeak) and the coordinate-system substrate the whole interval category rests on, with bedtools (CLI) and pybedtools/pyranges/pandas (Python). Covers the 0-based half-open vs 1-based-closed convention boundary and the start-1/end-unchanged conversion, the silent failures (chrom-name mismatch, CRLF, lexicographic-vs-version sort under -sorted), genome/chrom.sizes generation, sorting contracts, BED12 block invariants, validation, makewindows, cross-assembly liftover (liftOver/CrossMap), and BED<->VCF/BAM/FASTA conversion. Use when reading, creating, validating, sorting, lifting between genome builds, or converting interval files, preparing inputs for bedtools/tabix/bigBed, or debugging an off-by-one or empty-overlap result.

日本語の概要は準備中です。原文の説明を表示しています。

Enumerates virtual chemical libraries via reaction SMARTS transformations using RDKit and reaction templates, with explicit handling of atom mapping, RDChiral template extraction, product validation, RECAP/BRICS fragmentation, R-group decomposition, matched molecular pair analysis (MMPA), and Free-Wilson analysis. Use when generating combinatorial libraries from building blocks, enumerating analog series, deriving structure-activity rules, or extracting transformations from reaction data.

日本語の概要は準備中です。原文の説明を表示しています。

Performs retrosynthetic planning using AiZynthFinder (template-based MCTS), maintained or version-pinned template-free models, ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, configurable MCTS rewards, building-block availability, and forward-prediction checks. Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.

日本語の概要は準備中です。原文の説明を表示しています。

Use when ANY iOS or macOS build fails, a crash log needs diagnosing, a test run crashes, Xcode misbehaves, or an environment issue blocks work before code is the suspect. Covers build failures, dependency conflicts, simulator diagnostics.

日本語の概要は準備中です。原文の説明を表示しています。

Implement VoIP calling with CallKit and PushKit. Use when building incoming/outgoing call flows, registering for VoIP push notifications, configuring CXProvider and CXCallController, handling call actions, coordinating audio sessions, or creating Call Directory extensions for caller ID and call blocking.

日本語の概要は準備中です。原文の説明を表示しています。

Audits App Store submission readiness and rejection risk across current review guidelines, PrivacyInfo.xcprivacy and required-reason APIs, privacy labels, ATT, StoreKit payments, metadata, entitlements, widgets, and Live Activities. Use when preparing a submission, responding to rejection, reconciling privacy evidence, or separating upload blockers from cleanup.

日本語の概要は準備中です。原文の説明を表示しています。

Prevents crashes due to problematic scope-related API misuse caused by agent escalation into internal scope framework objects. Use when configuring properties of scope-related Simulink blocks or MATLAB objects — constrains the agent to documented APIs and directs users to the scope UI when a property is not programmatically accessible.

日本語の概要は準備中です。原文の説明を表示しています。

Model, simulate, and optimize Serializer/Deserializer (SerDes) systems — serial and parallel links — using MATLAB SerDes Toolbox. Design NRZ and PAM-N links (PAM3 through PAM16) — explore equalization architectures (FFE, CTLE, DFE), sweep or optimize parameters with genetic algorithms, and characterize channels from loss models, S-parameter files, or crosstalk scenarios. Process captured waveforms through equalization chains, build eye diagrams, and decompose jitter. Deliver IBIS-AMI models for Tx, Rx, Redriver, or Retimer by exporting to Simulink and compiling .ami/.ibs/.dll/.so files. Covers the full arc from initial design exploration and parameter optimization to compliance testing and compiled model validation, including custom datapath blocks for nonstandard equalization.

日本語の概要は準備中です。原文の説明を表示しています。

Design and implement adaptive filters using DSP System Toolbox System objects. Use when working with adaptive filtering, system identification, noise cancellation, echo cancellation, active noise control (ANC), channel equalization, inverse system identification, or adaptive prediction. Covers dsp.LMSFilter, dsp.RLSFilter, dsp.FilteredXLMSFilter, dsp.FrequencyDomainAdaptiveFilter, dsp.AffineProjectionFilter, dsp.BlockLMSFilter, dsp.AdaptiveLatticeFilter, dsp.FastTransversalFilter, maxstep(), and algorithm selection for adaptive filtering problems. Replaces deprecated adaptfilt.* objects (removed R2020a).

日本語の概要は準備中です。原文の説明を表示しています。

Spiral inductors, interdigital capacitors, baluns, resonators, phase shifters for impedance matching, DC blocking, and bias tees. TRIGGER: user asks to design or create a spiral inductor, interdigital capacitor, balun, resonator, phase shifter, or other passive RF component. Invoke BEFORE writing code — class names and property patterns are non-obvious. SKIP: filter design (use matlab-design-pcb-filter), coupler/splitter design (use matlab-design-pcb-coupler), transmission line design (use matlab-design-pcb-transmission-line), EM analysis (use matlab-analyze-em), material setup only (use matlab-manage-pcb-material).

日本語の概要は準備中です。原文の説明を表示しています。

Design and implement real-time audio processing chains using Audio Toolbox streaming objects. Use when building frame-based audio processing loops, multiband filters, dynamic range control, parametric EQ, level metering, loudness metering, SPL metering, octave-band analysis, sample rate conversion, frequency-domain filtering (long impulse responses, custom filter banks), or audio chains in Simulink. Covers visualization (visualize method), interactive tuning (parameterTuner), MIDI control, and Audio Toolbox Simulink blocks. Use when the user says "real-time audio", "streaming audio", "audio filter", "compressor", "equalizer", "level meter", "loudness meter", "SPL meter", "octave bands", "crossover filter", "audio chain", "MIDI control", "convolution reverb", "impulse response streaming", "frequency-domain filter", or asks to process audio frame-by-frame.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze AMS waveform data using Mixed-Signal Blockset utilities: phase noise measurement, clock jitter, anti-aliased resampling, timing measurements, lock time, INL/DNL, ADC/DAC calibration, HSpice import. Use when analyzing time-domain voltage from PLL/VCO/clock simulations, measuring phase noise from variable-step solver output, computing jitter, or resampling non-uniform data.

日本語の概要は準備中です。原文の説明を表示しています。

Unified skill for all MATLAB and Simulink report generation tasks. Covers report generation, PDF report, document generation, mlreportgen, Report Generator, template, TitlePage, Chapter, multipage HTML, HTMLPage, html-multipage, custom reporter, customizeReporter, template hole, page header, page border, company style package, branded reporters, buildTemplates, Simulink report, model documentation, slreportgen, block diagram report, model report, subsystem documentation, SystemDiagramFinder, SystemIO, ExecutionOrder, LookupTable, template style, page footer, TemplateSrc, report package, table variants, multiple HTML pages, PDF report generation, Word report, DOM API, FormalTable, BaseTable, Figure, FormalImage, Section.

日本語の概要は準備中です。原文の説明を表示しています。

Generate or improve MATLAB help text (documentation comments) for a function, class, or script file following MathWorks standards (H1 line, syntax paragraphs, See Also, 75-char lines). Read BEFORE writing MATLAB help — default patterns (Inputs:/Outputs: lists, block comments, uppercase See Also) produce non-conforming output. Use when writing, rewriting, fixing, or reviewing MATLAB help comments or function documentation.

日本語の概要は準備中です。原文の説明を表示しています。

Expert guidance for simulating RoadRunner scenarios via the MATLAB programmatic API and Simulink co-simulation. Use when the user wants to run a simulation, step through a simulation, control actors during co-simulation, add observers, attach sensors, retrieve simulation logs, or read/write scenario variables. Covers simulateScenario, createSimulation, ScenarioSimulation set/get, ActorSimulation getAttribute/setAttribute, addObserver, SensorSimulation, Simulink co-sim blocks, and publishActorBehavior. NOT for project setup, scene building, scenario authoring, or trajectory export.

日本語の概要は準備中です。原文の説明を表示しています。

Build Simulink models that co-simulate with Eclipse SUMO traffic simulator. Use when creating SUMO-Simulink co-simulation, traffic simulation, TraCI connection, vehicle-in-the-loop testing, or ADAS scenario validation with SUMO. Covers Server/Client setup, Reader/Writer/Actor block configuration, random traffic generation, ego vehicle control, and SUMO file creation. Also use when the user mentions SumoInterfaceLibrary, .sumocfg files, or wants to connect Simulink to an external traffic simulator.

日本語の概要は準備中です。原文の説明を表示しています。

Generate kickoff artifacts for a multi-phase program: umbrella plan, Program Goal Charter, session-goal block, per-phase plan stubs, and the 7-step per-phase inner loop reference.

日本語の概要は準備中です。原文の説明を表示しています。

Apply systematic problem-solving techniques when stuck. Use for complexity spirals, innovation blocks, recurring patterns, assumption constraints, simplification cascades, scale uncertainty.

日本語の概要は準備中です。原文の説明を表示しています。

Use when running VALIDATE V2-V3 fan-out. Two-layer investigation (4 dimension agents + per-section feasibility agents) synthesized into PASS/CONDITIONAL/BLOCKED net gate. Strategy-agnostic.

日本語の概要は準備中です。原文の説明を表示しています。

Verify claims, quotations, citations and references against live primary sources, and produce a reproducible audit record instead of an assertion. Use when asked to: check whether a quotation, verse, statistic, date, attribution or citation is accurate; verify references before publishing a report, thesis, article, slide deck or legal filing; confirm a text against an authoritative database; cross-check a claim across independent sources; build a citation register or verification appendix; find out whether two datasets agree; detect a misattributed or fabricated quotation; or audit a document's existing citations. Source-agnostic by design, with working providers for REST/JSON APIs, scraped HTML, bulk corpora, bibliographic catalogues (OpenLibrary), DOI resolution (Crossref) and reference works (Wikipedia) -- including scriptural tiers (Qur'an.com, sunnah.com and an independent hadith corpus) with full diacritic handling for Arabic, Hebrew, Greek and any script with optional marks. Covers content-addressed matching when sources disagree on numbering, graded match verdicts, byte-level integrity checks, published-string verification, and a catalogue of silent failure modes (identifier divergence, mojibake, scraper blocking, false-positive keyword rules, missing glyphs, unreliable PDF text layers).

日本語の概要は準備中です。原文の説明を表示しています。

Diagnose App Store submission blockers and operate review health with asc, including readiness validation, repair routing, status monitoring, cancellation, and retry decisions. Use when validation fails, a version is not in a valid state, review status is unclear or stuck, or a failed submission must be repaired and retried. For staging, upload, publication, and submission execution, use asc-release-flow.

日本語の概要は準備中です。原文の説明を表示しています。

Generate a comprehensive session report with per-model token usage (input, output, cache_read, cache_write including compaction baselines), cost breakdown via the pricing engine, tool invocations, agent hierarchy, compaction events, API errors, turn durations, and thinking block counts. Use when reviewing a specific session or summarizing activity over a date range.

日本語の概要は準備中です。原文の説明を表示しています。

Debug a specific session by inspecting its full event chain (PreToolUse, PostToolUse, Stop, SubagentStop, Compaction, APIError, TurnDuration, Notification events), agent hierarchy (recursive parent/child tree with subagent_type and depth), token usage with compaction baselines, workflow intelligence data (orchestration DAG, error propagation by depth), and session metadata (thinking_blocks, turn_count, total_turn_duration_ms).

日本語の概要は準備中です。原文の説明を表示しています。