「ml」の検索結果

Classify constitutional (germline) copy number variants for clinical reporting using the 2019 ACMG/ClinGen technical standards points-based framework, with ClassifyCNV and AnnotSV for semi-automated scoring. Covers the separate copy-number-loss and copy-number-gain rubrics, the five-tier classification, ClinGen haploinsufficiency/triplosensitivity and dosage-sensitive regions, de novo and segregation evidence, and population-frequency benign evidence. Use when assigning pathogenic/likely-pathogenic/VUS/likely-benign/benign to a constitutional CNV, scoring a CNV against ACMG/ClinGen criteria, or distinguishing the automatable evidence from the case-specific evidence requiring manual input.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes CRISPR drug-modifier (chemogenomic) screens with drugZ (Colic et al. 2019 Genome Med), a bidirectional Z-score method that identifies synthetic-lethal sensitizing genes and resistance-conferring suppressor genes from vehicle vs drug comparisons. Covers vehicle-anchored design (not Day-0), the bidirectional Z math giving greater sensitivity to small-effect hits than MAGeCK / STARS / edgeR / RIGER on drug screens, per-gene sumZ and normZ, synth (sensitizer) vs supp (suppressor) FDR, multi-dose handling, integration with control sgRNAs, and comparison with MAGeCK MLE with dose covariate. Use when running a drug-modifier CRISPR screen, identifying sensitizing or resistance genes for a drug candidate, choosing drugZ vs MAGeCK MLE for chemogenomic analysis, troubleshooting low-effect drug screens where MAGeCK lacks sensitivity, or designing a drug-screen layout (vehicle vs drug arms).

日本語の概要は準備中です。原文の説明を表示しています。

Calculates tumor mutational burden from WES/WGS/panel data with Friends of Cancer Research harmonization equations, per-assay calibration (FDA 10/Mb = 7.8 TSO500 = 8.4 OncomineTML), synonymous/indel/germline filtering, hypermutator tiering, blood TMB, and integration with HLA-LOH and neoantigen quality (Luksza 2017 fitness). Use when assessing ICI eligibility under tumor-specific cutoffs (McGrail 2021), comparing tissue vs bTMB, or auditing TMB-H reporting against ESMO 2024 and FDA pembrolizumab pan-tumor 2020.

日本語の概要は準備中です。原文の説明を表示しています。

Queries ClinVar for variant pathogenicity classifications, ClinGen VCEP curations, and somatic-vs-germline interpretations via REST API, weekly VCF, or bulk XML. Use when determining clinical significance, triangulating conflicting interpretations, or aggregating evidence against the ACMG/AMP framework with ClinGen SVI specifications.

日本語の概要は準備中です。原文の説明を表示しています。

Decompose total effects into direct and indirect paths through mediators using mediation, CMAverse 4-way, HIMA/HIMA2 high-dimensional, BAMA, two-step / MVMR mediation, or double-ML medDML. Use when testing whether a molecular phenotype (expression, methylation, protein) mediates a treatment-outcome relationship, decomposing exposure-mediator interaction via VanderWeele 4-way, screening high-dimensional EWAS mediators, or running MR-based mediation when sequential ignorability is implausible.

日本語の概要は準備中です。原文の説明を表示しています。

Capture and review Agent Skill observations, and create, run, diagnose, or iteratively improve Skill evaluations (evals) with the skill-up CLI. Use when the user asks to record explicitly attributed Skill usage or feedback; review observations or user-supplied traces/transcripts; turn an approved observation into a regression case; evaluate, test, regress, verify, fix, improve, iterate, or evolve a Skill; add or strengthen eval cases; write eval.yaml/case.yaml; run skill-up run/validate/list-cases/report/import/init; or migrate from Anthropic evals.json. Plugin observation capture/review require either the Codex skill-up plugin or an observer-enabled DSH skill-up plugin. User-supplied external evidence can be reviewed without a plugin; evaluation remains multi-engine.

日本語の概要は準備中です。原文の説明を表示しています。

Embeds and controls web content in SwiftUI with WebKit for SwiftUI, including WebView, WebPage, navigation policies, JavaScript execution, observable page state, link interception, local HTML or data loading, and custom URL schemes. Use when building iOS 26+ article/detail views, help centers, in-app documentation, or other embedded web experiences backed by HTML, CSS, and JavaScript.

日本語の概要は準備中です。原文の説明を表示しています。

Use Apple CryptoKit for Swift cryptographic primitives. Use when hashing with SHA-2 or SHA-3, generating HMACs, encrypting with AES-GCM or ChaChaPoly, signing with P256/P384/P521/Curve25519 or ML-DSA keys, performing ECDH, HPKE, ML-KEM, or X-Wing key exchange, using Secure Enclave CryptoKit keys, or migrating CommonCrypto code to CryptoKit.

日本語の概要は準備中です。原文の説明を表示しています。

Use when building, modifying, or reviewing a Stripe App — or when the user describes something that implies one (e.g. "add a panel to the customer page", "customize my Stripe Dashboard", "react to Stripe events from my app", "connect my service to Stripe without sharing API keys"). Covers the full app development workflow (scaffold, preview, upload, versioning), UI extension architecture (sandboxed iframe, Stripe UI toolkit, viewports), extension types (UI extensions, backend-only, extension interfaces, embedded apps), authentication (platform keys, OAuth, restricted API keys), stripe-app.yaml manifest setup (permissions, viewports, CSP), webhook configuration for apps, Secret Store API, `fetchStripeSignature` auth, and marketplace publishing, plus submitting one agentic feedback report after a build. Use when the user mentions Stripe Apps, UI extensions, @stripe/ui-extension-sdk, @stripe/extensibility-sdk, script extensions, stripe-app.yaml, Dashboard extensions, or customizing the Stripe Dashboard.

日本語の概要は準備中です。原文の説明を表示しています。

スライド設計規約 slide-rules.md を核に、経営会議品質のスライドを作るスキル。作成前に規約を読み、HTMLパーツ集（基本27＋追加35の62型）から該当パーツをコピーして組み、規約の範囲で型に囚われず調整し、check_deck.py の機械チェック FAIL 0 で仕上げる。型カタログはレイアウトの発想帳であり、合わせる対象ではない。既存の PowerPoint 資料を渡され、そこへ差し込むページを PPTX で求められたときだけ、その資料のマスターの上に直接組む（slide-rules §8.7）。トリガー例:「コンサル品質のスライドを作って」「規約に沿ったデッキで」「型カタログから選んで」「この pptx に足すページを同じ書式で」。

Use whenever "project" or "matlab.toml" is mentioned in a MATLAB context. This includes creating, editing, organizing, or configuring MATLAB projects, declaring MATLAB package dependencies or reference projects, setting up paths, lifecycle scripts, shortcuts, MATLAB packages, or asking about project structure.

日本語の概要は準備中です。原文の説明を表示しています。

Build industrial-grade SCADA/HMI dashboards in MATLAB following industrial-HMI conventions (ISA-101-aligned): gray-field philosophy, alarms at source, write safeguards, fixed-range trends, drill-down layout. Produces a real App Designer app (.mlapp, or plain-text .m+.xml on R2026b+) by handing serialization to the matlab-build-app skill when available, and falls back to a programmatic .m app otherwise. Use when wrapping OPC UA / Modbus / MQTT / OSI PI / PI AF monitoring scripts into a live operator app, building plant overviews, designing operator dashboards, or any time a user asks for a "SCADA dashboard", "HMI", "plant dashboard", "operator screen", or "industrial monitoring app" in MATLAB. Trigger on: SCADA, HMI, industrial dashboard, plant overview, operator screen, uigauge, uilamp, alarm banner, gray-field, ISA-101, OPC UA dashboard, setpoint, write safeguards, alarm visualization, OSIsoft PI, AVEVA PI, PI Server, PI Data Archive, PI AF, PI Asset Framework, piclient, afclient.

日本語の概要は準備中です。原文の説明を表示しています。

スライド設計規約 slide-rules.md を核に、経営会議品質のスライドを作るスキル。作成前に規約を読み、HTMLパーツ集（基本27＋追加35の62型）から該当パーツをコピーして組み、規約の範囲で型に囚われず調整し、check_deck.py の機械チェック FAIL 0 で仕上げる。型カタログはレイアウトの発想帳であり、合わせる対象ではない。既存の PowerPoint 資料を渡され、そこへ差し込むページを PPTX で求められたときだけ、その資料のマスターの上に直接組む（slide-rules §8.7）。トリガー例:「コンサル品質のスライドを作って」「規約に沿ったデッキで」「型カタログから選んで」「この pptx に足すページを同じ書式で」。

Bash 编写规范。当用户操作 .sh、Dockerfile、Makefile、.yml、.yaml 文件， 或在 Markdown 中编写 bash/shell 代码块时触发。 包含注释规范、文件写入方式、Heredoc 引号规则、权限路径、脚本规范等。

日本語の概要は準備中です。原文の説明を表示しています。

当用户操作 .sh、Dockerfile、Makefile、.yml、.yaml 文件，或在 Markdown 中编写 bash 代码块时触发。提供 Bash 编写规范。

日本語の概要は準備中です。原文の説明を表示しています。

Generate a complete, deployable landing page from a brief. Produces a single self-contained HTML file with Tailwind CSS (via CDN), responsive design, dark mode, semantic HTML, and OG meta tags. Sections: hero with CTA, features, social proof, pricing (optional), FAQ, footer. Use when building a marketing page, product launch page, coming soon page, or any standalone landing page. Triggers: 'landing page', 'create a page', 'marketing page', 'launch page', 'coming soon page', 'one-page site'.

日本語の概要は準備中です。原文の説明を表示しています。

Generate complete SEO setup for local business websites — HTML head tags, JSON-LD LocalBusiness schema, robots.txt, sitemap.xml. Australian-optimised with +61 phone, ABN, suburb patterns. Use whenever the user wants SEO for a local business (tradesman, café, clinic, agency, retailer), needs JSON-LD structured data, asks for LocalBusiness schema, or wants meta tags / robots.txt / sitemap for a suburb-serving business.

日本語の概要は準備中です。原文の説明を表示しています。

Reviews and migrates deprecated wildcard (*) values in Power Pages Web API fields site settings to least-privilege explicit Dataverse columns. Use whenever a user mentions Web API wildcard or select-all remediation, fields settings containing *, data-exposure review, wildcard deprecation readiness, or Web API failures after wildcard retirement. Applies to both traditional sites using HTML, CSS, JavaScript, Liquid, and downloaded YAML, and SPA sites using React, Vue, Angular, Astro, or TypeScript. The agent must inspect every source Web API call and consumer, report exact fixes for every wildcard, report every already-explicit configuration, apply approved edits, and verify no wildcard remains.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a task involves game textures or materials through the Scenario MCP: seamless or tileable textures, themed texture packs (brick, wood, stone, floors, hand-painted), PBR materials (albedo, metallic, roughness, normal) on 3D assets, retexturing a mesh, material iteration from reference images, texture upscaling that must preserve tiling, or sizing textures for game engines. Keywords: seamless texture, tileable, PBR, material, retexture, texture upscale, surface.

日本語の概要は準備中です。原文の説明を表示しています。

用户要做界面、网页、海报、图表或信息图、示意图、原型这类视觉设计稿时用：在工作目录写一份设计稿（canvas.json 加每块画板一个 .dc.html），校验通过后线程里出现设计稿卡片，用户在功能区预览、编辑与标注。也用于按用户的意见或设计稿标注改已有的设计稿。幻灯片不用它（用 slides），视频画面里的字卡与动效也不用它（用动效图形）。

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要在视频上加一段动效图形时用：下横栏（姓名职务）、关键词字幕、大数字与图表、标注与引导、品牌贴片与片尾、倒计时与进度。不选模板，按规则写一个自包含的 HTML 画面（时间的纯函数），打包成代码包导入后放上时间线。只加静态文字、贴纸或已有的文字动画预设时不用；整条成片的规划看「从简报到成片」。

日本語の概要は準備中です。原文の説明を表示しています。

用户要做幻灯片、演示文稿、讲稿或汇报用的页面时用：在工作目录里写一份 deck（deck.json 加每页一个 HTML 文件），校验通过后线程里出现幻灯片卡片，用户在功能区预览、编辑与标注。可以套用工作目录里的设计系统；需要插图时可以用图片生成模型画好放进页面。也用于按用户的意见或标注改已有的幻灯片。视频画面里的字卡、下横栏与动效不用它（用动效图形）。

日本語の概要は準備中です。原文の説明を表示しています。

Expert ITAR compliance advisor for US defense contractors, exporters, and manufacturers. Use this skill for any question about 22 CFR Parts 120-130, the United States Munitions List (USML), DDTC registration, export license applications (DSP-5/73/94), Technical Assistance Agreements (TAA), Manufacturing License Agreements (MLA), brokering regulations (Part 129), deemed export rules for foreign nationals, technology control plans, voluntary disclosures, violation mitigation, jurisdiction determination (ITAR vs EAR), or US Munitions List category scoping. Trigger even if the user doesn't say "skill" — any ITAR or US defense export control question should use this skill.

日本語の概要は準備中です。原文の説明を表示しています。

Designs production-grade ML pipeline infrastructure with experiment tracking, Kubeflow/Airflow DAGs, feature store schemas, model registries, and automated retraining workflows.

日本語の概要は準備中です。原文の説明を表示しています。