「three」の検索結果

Use when you need to write or improve integration tests for Quarkus — including @QuarkusTest, Dev Services for automatic container provisioning, Testcontainers via QuarkusTestResourceLifecycleManager, WireMock for external HTTP stubs, @QuarkusIntegrationTest for black-box testing against packaged artifacts, REST Assured, data isolation strategies (@TestTransaction vs @BeforeEach cleanup), and Maven Surefire/Failsafe three-tier split (*Test, *IT, *AT). This should trigger for requests such as Add or improve integration tests in a Quarkus project; Configure Testcontainers or Dev Services for Quarkus tests; Add WireMock stubs for external HTTP dependencies in Quarkus integration tests; Set up @QuarkusIntegrationTest for packaged artifact or native binary testing; Fix test data isolation or configure Maven Surefire/Failsafe split. Part of cursor-rules-java project

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Self-review, audit, or verify CS/AI/ML paper drafts as a critical peer reviewer. Three-round review (evidence→argument→style) with Verification Status and debt tracking. Use when: reviewing a paper draft before submission, checking evidence compliance of claims, simulating peer reviewer feedback, verifying citation closure and evidence debts, performing cross-section consistency checks. Triggers on: 审修, self review, 自查, verification, revise, 修订, check draft, 审稿, evidence compliance, peer review, 论文审查, draft audit, 验证论文, 检查引用, cross-section review.

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Run a health check on an existing project: dependency audit, security scan, test runner detection, CI/CD evaluation, and missing configuration analysis. Maps the three execution gates (pre/in/post) from /10x-bootstrapper to an assessment framework for existing codebases. Reads optional context/foundation/stack-assessment.md from /10x-stack-assess to focus checks on identified gaps. Writes context/foundation/health-check.md with findings, prioritized fixes, and an agent-readiness verdict. Use when the user has an existing project and wants to verify its health before working with an agent. Trigger phrases: "health check", "check my project", "audit my project", "is my project healthy", "sprawdź projekt", "audyt projektu", "health-check", "project health". Use AFTER /10x-stack-assess (brownfield chain), BEFORE agent onboarding (m1-l4).

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Turn character reference images into reusable, rigged voxel 3D assets for Blender and Three.js through an imagegen turnaround and user-approval workflow. Use when Codex needs to preserve a character's likeness across front, side, and back views; create or revise Minecraft-like cube-headed models; prevent missing rear hair or clothing; split features between block geometry and face/clothing textures; generate GLB and editable .blend files; add walk/smash-compatible rigid-part pivots; or diagnose why a voxel conversion is not recognizable.

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INTERNAL/HELPER skill — do NOT invoke directly from a user query. This is the shared formatter/poster used by create-issue, create-issue-from-issue-number, and update-issue. It formats an implementation-ready GitHub Issue body, runs the pre-posting checklist, executes `gh issue create` or `gh issue edit`, and optionally posts a 確認事項 follow-up comment. Invoke this skill ONLY from one of the three parent skills via the Skill tool, after the parent has completed analysis. If a user asks to 'format an issue body' or similar, route them to the appropriate parent skill (/create-issue, /create-issue-from-issue-number, or /update-issue) rather than invoking this one directly.

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Quality control for IMC/MIBI data across pixel, channel, image, slide, and batch levels, covering Poisson-count SNR (cell-level Gaussian-mixture and empty-channel comparison), spillover-matrix QC (the three physical sources), drift and the missing EQ-bead analog, acquisition artifacts, and sample-of-origin batch effects. Use when deciding whether to keep or drop a channel, ROI, or slide, distinguishing a dim antibody from a failed one, reading a spillover matrix, or diagnosing batch-driven clustering before analysis.

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Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.

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Evaluates genome assembly quality across the three orthogonal axes - contiguity (QUAST auN/NG50/NGx, not bare N50), completeness (BUSCO/compleasm gene-space plus Merqury k-mer completeness), and correctness (reference-free Merqury QV, Inspector/CRAQ structural errors, asmgene false-duplication/collapse). Covers why N50 is the most-gamed metric, why QV measured on the polishing reads is circular, distinguishing uncollapsed haplotigs from real WGD, and the EBP/VGP 6.C.Q40 standard. Use when judging whether an assembly is good enough to annotate or publish, comparing assemblers, diagnosing a fragmented or duplicated assembly, or assessing a phased diploid assembly.

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Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.

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Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.

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Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.

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Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.

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Identifies differentially bound ChIP-seq regions between conditions using DiffBind, csaw (sliding windows), DESeq2/edgeR/PyDESeq2 on count matrices, NormR (control-aware), or MAnorm2. Distinguishes three distinct normalization problems (composition bias, trended bias, global shifts) and matches each to its appropriate fix including spike-in scaling. Use when comparing ChIP-seq binding between experimental conditions, choosing normalization for global vs local changes, integrating spike-in data, or reconciling DiffBind/DESeq2 disagreement.

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Perform multiple sequence alignment using MAFFT, MUSCLE5, ClustalOmega, or T-Coffee. Guides tool and algorithm selection based on dataset size, sequence divergence, and downstream application. Use when aligning three or more homologous sequences for phylogenetics, conservation analysis, or evolutionary studies.

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Spec-locked TDD with a mutation-testing gate — refine the intent into an immutable Gherkin contract (SHA-256 frozen), implement under the three laws of TDD, pass a judge audit, and merge only if every mutant dies.

日本語の概要は準備中です。原文の説明を表示しています。

Iteratively detects and auto-fixes technical debt in a codebase using three quality criteria from debt-analysis references: conditional branch simplification, encapsulation, and separation of concerns. Applies fixes directly to code, runs existing tests to verify no regressions, re-analyzes, and loops until all high-severity issues are resolved or max iterations (5) reached. Use this skill when you want to automatically improve code quality with real code changes, reduce technical debt systematically, or clean up code to meet quality standards. Trigger on phrases like "fix technical debt", "clean up code quality", "refactor and fix issues", "improve code quality automatically", "apply debt fixes", "fix code problems", "eliminate debt".

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Hand-drawn paper-wireframe template — white paper background, monochromatic ink palette, SVG turbulence "wobble" filters for pen-quiver authenticity, handwritten fonts (Caveat / Kalam / Ma Shan Zheng / Long Cang), wavy dividers, sketch-rect overlays, marginalia annotations. For PRD illustrations, IA flow docs, low-fidelity layout exploration, "draft / not final" stakeholder communication. Three skeletons (single-page editorial / app multi-screen flow / IA sitemap) — pick one up front based on the artifact, do NOT inherit only the brush strokes.

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Build premium scroll-driven web pages and product showcases inspired by high-end app, hardware, and product interaction patterns. Use for Raycast-like, Apple-like, NVIDIA-like, RTX/GPU, SaaS, AI browser, parallax, sticky scroll, pinned reveal, Three.js GLB model, Web Audio sound effect, responsive accessibility, and performance-safe frontend requests.

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Premium calm-tech SaaS landing template — bilingual (CN/EN) literary voice over a dark forest-night palette with warm gold accent, Cormorant + Noto Serif SC, Three.js procedural forest hero, station-based scrolling narrative, custom cursor. Built for ambient-AI / creative-tool / philosophical SaaS, not loud commercial launch.

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Use when an existing skill must be refactored to cut context and ambiguity without losing behavior, safety or fallbacks — 'refatorar a skill', 'reduzir esta SKILL.md', 'revisar skill com métricas' — with before/after metrics, preserved invariants and three review rounds.

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Use when a change is small and already understood - at most three files, such as a typo, a config value, a rename, or a one-line bugfix - and a plan file would cost more than the change

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Three-axis orchestrator: (1) clean section boundaries — naming, routes, views, ViewModels, DB ownership, cross-section access; (2) internal cohesion — no EF in service layer, caching in service only, proper interfaces, reusable ViewComponents, architecture-test coverage; (3) focused tests — grouped under the section, covering invariants/negatives/triggers, pruned of redundancy. Push-and-bot-review loop. Use when a sizable PR landed, a section shows arch drift, or /pr-review returned a non-trivial violation list. Camps is the gold-standard reference.

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Systematically QA test a web application and fix bugs found. Runs QA testing, then iteratively fixes bugs in source code, committing each fix atomically and re-verifying. Use when asked to "qa", "QA", "test this site", "find bugs", "test and fix", or "fix what's broken". Proactively suggest when the user says a feature is ready for testing or asks "does this work?". Three tiers: Quick (critical/high only), Standard (+ medium), Exhaustive (+ cosmetic). Produces before/after health scores, fix evidence, and a ship-readiness summary. For report-only mode, use /qa-only. (gstack) Voice triggers (speech-to-text aliases): "quality check", "test the app", "run QA".

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Interactive developer experience plan review. Explores developer personas, benchmarks against competitors, designs magical moments, and traces friction points before scoring. Three modes: DX EXPANSION (competitive advantage), DX POLISH (bulletproof every touchpoint), DX TRIAGE (critical gaps only). Use when asked to "DX review", "developer experience audit", "devex review", or "API design review". Proactively suggest when the user has a plan for developer-facing products (APIs, CLIs, SDKs, libraries, platforms, docs). (gstack) Voice triggers (speech-to-text aliases): "dx review", "developer experience review", "devex review", "devex audit", "API design review", "onboarding review".

日本語の概要は準備中です。原文の説明を表示しています。