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Search LCSC Electronics for electronic components — find parts by LCSC number (Cxxxxx) or MPN, check stock/pricing, download datasheets, analyze specifications. Sister company to JLCPCB, same parts library. Sync and maintain a local datasheets directory for a KiCad project, or use batch MPN-list seeding (`--mpn-list`) for bulk workflows without a project. No API key needed — uses the free jlcsearch community API. Use this skill when the user mentions LCSC, JLCPCB parts library, JLCPCB assembly parts, production sourcing, Cxxxxx part numbers, needs to find LCSC equivalents for parts, is preparing a BOM for JLCPCB assembly, or wants to download datasheets and LCSC is available. For package cross-reference tables and BOM workflow, see the `bom` skill.

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BOM (Bill of Materials) management for electronics projects — the workflow skill that coordinates DigiKey, Mouser, LCSC, element14, JLCPCB, PCBWay, and KiCad skills around a unified BOM lifecycle. Create, update, and maintain BOMs with part numbers, costs, quantities stored as KiCad symbol properties. ALWAYS trigger this skill for any task involving component sourcing, pricing, ordering, distributor searches, BOM export, or fabrication preparation — even if the user names a specific distributor or fab house (e.g. "search DigiKey for...", "generate JLCPCB BOM", "order from Mouser"). This skill analyzes the schematic for sourcing gaps, recommends which distributor/fab skills to call for each gap, and writes results back as symbol properties — the agent (or user) performs the actual searches via the called skills. Also trigger on phrases like "what parts do I need", "order components", "how much will this cost", "export for JLCPCB", "find parts for this board", "compare pricing", or "check stock".

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Delegate tasks to ANY CLI agent (claude, codex, aider, ...) running in a detached tmux session, with a race-safe done-signal protocol and multi-turn iteration. Use when delegating work to a non-Claude CLI agent, when the user says "tmux delegate", "run agent in tmux", "delegate to codex/aider", or when executor work should run in an observable background terminal instead of the Agent tool.

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Source authentic, high-res PUBLIC-DOMAIN artwork from museum open-access APIs (Met, Cleveland, SMK, Rijksmuseum, NGA, Art Institute of Chicago, Getty, Smithsonian) instead of AI-generated or generic-stock imagery. The default move whenever a visual needs an aesthetic, credible image (blog heroes, decks, social cards, essay/spec figures). Verified keyless recipes + licensing rules inside.

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Review generated or changed WooCommerce code — extensions, payment and shipping integrations, checkout customizations, and order/product logic — before it ships. Best used reactively after an agent writes, edits, or reviews code touching WooCommerce APIs: wc_get_order, wc_get_orders, wc_get_product, WC() cart or session, woocommerce_* hooks, Store API endpoints, payment gateways, order or product meta, HPOS, subscriptions, or bookings. Use on 'review this Woo plugin', 'is this HPOS compatible', or after tasks like 'write a WooCommerce extension', 'add a checkout field', 'hook into the order flow', or 'update stock'. Enforces HPOS-safe order access, CRUD over direct meta, feature-compatibility declarations, server-side checkout validation, money-handling discipline, and hooks over template overrides. DO NOT USE for WordPress code without WooCommerce APIs (use wp-guard), generic code review (use clean-code-guard), test review (use test-guard), or store configuration and admin-screen questions.

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Use when positioning an Agricultural Systems (AgSy) manuscript against the literature so it reads as a systems contribution. AgSy readers span agronomy, modelling, livestock, economics, environment, and food-system science, so the paper must engage the systems and modelling literatures they expect — not only one subfield. Stakes the contribution; it does not write the lit review.

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Use when running the final pre-submission preflight for an Advanced Materials manuscript — article type, format, files, Supporting Information, TOC graphic, ORCID, and metadata for the Wiley submission system. Verifies submission readiness; does not write content.

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Use when preparing ACM CCS appendices and supplementary material, including the ethics considerations appendix, protocol transcripts, formal proofs, measurement tables, and anonymized supporting material under the 12-page body limit, anonymity, and reviewer-discretion constraints for a security paper.

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Use when strengthening AAMAS reproducibility evidence for interaction claims, including proofs and game definitions, opponent and population sets, self-play protocols, random seeds, compute, uncertainty on strategic outcomes, baselines, and consistency between what the paper claims about agents and what the artifact can actually show.

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Render pixel-accurate Apple Notes (iPhone, light mode) screenshot mockups from a JSON note spec. Outputs HTML + PNG at the iPhone 16/15 Pro native 1180×2556. Supports paragraphs, images, checklists, dividers, autocorrect underline, smart quotes, and an optional iOS keyboard chrome overlay used by the parent video-ad molecule.

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Assemble a creator picture-in-picture product-listicle ad from a config — the creator stays FULL-FRAME the whole beat (voice plus lips generated together per beat, no separate VO, no cut to a full-frame product shot), and on each product beat three persistent overlays ride on top for the WHOLE beat — a title pill top-center, the DEMO in a rounded PiP window top-right (the brand's real UGC clip MUTED, or for a no-UGC brand the product's own autocropped UI still / screen-recording sized to fill the window), and a bottom product card (rounded thumbnail plus 'N · CATEGORY' small-caps plus product NAME in a serif face). Hook plus CTA beats are the creator full-frame with the title pill only. Assembly builds ONE full-1080x1920 transparent overlay PNG per beat, overlays it on the creator clip (cover-scaled to 1080x1920) for the whole beat keeping the native audio, concats all beats, then burns captions LAST as timed PIL PNG overlays (this ffmpeg has no libass) timed deterministically from the known per-beat script. This is the FREE deterministic assembly stage (overlay-PNG build plus cover-scale composite plus concat plus PIL-PNG caption burn); the creator anchor and the N native talking clips come from create-image-fal (Seedream v5 Pro) and create-video-fal (Seedance 2.0). Use for the creator-pip-listicle format.

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Pull company financials, SEC filings, and analyst consensus for a public company. Use this skill whenever the user says "10-K", "10-Q", "earnings", "revenue of", "financials for", "analyst rating for", "price target for", or provides a stock ticker. Combines SEC EDGAR for official filings with Yahoo Finance / TipRanks for analyst data. Search + scrape only; no interact needed.

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Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.

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Extracts cfDNA fragmentomics features (DELFI genome-wide short/long ratios, WPS nucleosome positioning, Griffin GC-corrected accessibility profiles, end-motifs/MDS, OCF) for cancer detection and tissue-of-origin from plasma WGS. Centers on the nuclease-footprint reframe (every feature re-reads one nucleosome object), the mandatory GC correction, and the cross-protocol non-comparability that breaks naive classifiers. Runs FinaleToolkit (real CLI/Python, MIT) and the Griffin Snakemake pipeline; DELFI is a method, not a package. Use when deriving fragment-based signal from cfDNA, choosing a feature family for detection vs subtyping, or diagnosing why a fragmentomic model failed validation.

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Assembles genomes de novo from noisy long reads (Oxford Nanopore R9/R10/Dorado, PacBio CLR) with Flye (repeat graph), Canu (correct-trim-assemble OLC), NextDenovo, Shasta, Raven, wtdbg2, or miniasm, and reconciles bacterial assemblies into a consensus with Trycycler/Autocycler. Covers matching the input flag to the basecaller era (--nano-hq vs --nano-raw), why a raw long-read assembly is contiguous but low-QV and not finished until polished, haplotig false-duplication and purge_dups, coverage and read-N50 as non-substitutable inputs, and mid-read adapter de-chimerization. Use when assembling a bacterial or eukaryotic genome from ONT or PacBio noisy reads, choosing a long-read assembler, or diagnosing an over-collapsed or duplicated assembly. For PacBio HiFi use hifi-assembly instead.

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Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. Encodes Ensembl version stripping with GENCODE _PAR_Y preservation, the Ziemann 2016 Excel autocorrect debacle and Bruford 2020 HGNC renames (SEPT*->SEPTIN*, MARCH*->MARCHF*, MARC*->MTARC*, DEC1->DELEC1), OCT4/POU5F1 alias resolution, biomaRt archive endpoints for release pinning, the `filters` (plural) gotcha, MANE Select for clinical reporting, cross-species orthology via Ensembl Compara / OMA / OrthoDB, and tx2gene construction for tximport. Use when converting gene IDs across systems, handling renamed symbols, building tx2gene, pinning to a specific Ensembl release for reproducibility, or mapping cross-species orthologs.

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Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein / chromatin readout. Covers experimental design (direct-capture Perturb-seq Dixit 2016 vs CROP-seq 3'UTR-barcoded Datlinger 2017 vs ECCITE-seq vs Multiome), MOI for sgRNA assignment, escaper-cell filtering (Mixscape, Papalexi 2021), SCEPTRE NB GLM + permutation for low-MOI (Barry 2024 Genome Biol 25:124), the Pertpy framework, factor decomposition, genome-scale Perturb-seq (Replogle 2022 Cell, 2.5M cells), and per-perturbation single-cell DE. Use when running a single-cell CRISPR screen, choosing direct-capture vs CROP-seq architecture, filtering escaper cells, performing single-cell DE, integrating Perturb-seq with pathway analysis, scaling to GW CRISPRi via Replogle protocol, or analyzing multi-omics screens.

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Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.

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Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda scheduling, soft-core potentials, MBAR/BAR analysis, cycle-closure validation, and protocol-appropriate enhanced sampling. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.

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Computes sample size and power for clinical trials including continuous, binary, and time-to-event endpoints; superiority, non-inferiority, and equivalence designs; FDA 2016 non-inferiority margin selection with M1/M2 framework; Schoenfeld 1981 and Lakatos 1988 for survival; Schuirmann TOST and 80-125% bioequivalence; minimum clinically important difference (MCID) vs δ distinction. Use when justifying trial size in protocol or SAP per CONSORT 2025 item 16a.

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Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

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Read, write, and convert multiple sequence alignment files using Biopython Bio.AlignIO. Supports Clustal, PHYLIP, Stockholm, FASTA, Nexus, and other alignment formats for phylogenetics and conservation analysis. Use when reading, writing, or converting alignment file formats.

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ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. Use when assessing whether an ATAC-seq library passes ENCODE acceptance criteria, diagnosing transposition artefacts, comparing Omni-ATAC vs standard prep quality, or selecting which replicates to drop before peak calling.

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Use when implementing, testing, or evaluating ANY Apple Intelligence, on-device AI, or speech-to-text feature. Covers Foundation Models, @Generable, LanguageModelSession, Tool protocol, eval suites, model-as-judge scoring, SpeechTranscriber, CoreML.

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