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概要と使いどころ
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.
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Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CA-CTCF/CA-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.
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Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.
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Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.
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Estimates SNP heritability and partitions it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.
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This skill should be used when creating Ultralytics-branded content of any kind, including PDF, PPTX, Canva, or Google Slides presentations, DOCX documents, marketing or newsletter HTML emails, social media post copy or visuals, website or landing page designs, and dataset or model result visuals. Provides official colors, typography, logo rules, naming rules, and tone of voice from ultralytics.com/brand.
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AWS Cognito user authentication and authorization service. Use when setting up user pools, configuring identity pools, implementing OAuth flows, managing user attributes, or integrating with social identity providers.
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Shopify/DTC brand protection toolkit. Detect counterfeit stores, unauthorized resellers, and trademark violations. Includes DMCA takedown templates, domain monitoring, and social media infringement detection. No API key required.
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Review strategy for TikTok Shop — encouraging reviews, responding, leveraging UGC, social proof
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Full-stack e-commerce marketing strategy builder. Analyzes your product, market, and competitors, then builds a complete omnichannel marketing plan covering paid ads, SEO, email/SMS, content marketing, social media, influencer partnerships, and referral programs. Includes target audience persona, competitive landscape, channel prioritization with budget allocation, content direction, and a 90-day action plan. Works for any e-commerce platform — Shopify, Amazon, Etsy, WooCommerce, TikTok Shop, and more. No API key required.
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Brand monitoring tool for tracking mentions across social media platforms. Monitor Reddit, Google News, YouTube, and DuckDuckGo for brand mentions. Includes sentiment analysis, trend tracking, crisis detection, and competitor comparison. No API key required for basic monitoring.
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Use when the operator wants a hero or meta image for a Prisma blog post; asks to create or generate a blog hero, cover, social card, Open Graph, or YouTube image; mentions cover art, a blog thumbnail, cover.svg/hero.svg/meta.png; references content-create-hero-image; or wants to interactively design cover imagery in Prisma's 2026 brand (light paper, prism accents, Sora). Produces an editable SVG hero plus a pixel-exact PNG meta image, and includes an interactive mode and a built-in design-review pass.
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24/7 autonomous business operations orchestrator with business health scoring, canary monitoring, and safety guardrails. Schedules and runs all business functions automatically — content publishing, social media posting, outreach sequences, ad monitoring, financial reporting, health checks, and post-deploy verification. Use when the user wants to automate operations, schedule tasks, set up autonomous workflows, or says 'automate this', '24/7', 'run automatically', 'schedule', 'cron', 'autonomous', or 'set and forget'.
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Automated content creation pipeline for business growth. Creates blog posts, landing pages, email sequences, social media content, and video scripts with a supply-demand topic gate, 5-dimensional quality diagnosis, one-core resonance check, per-sentence information density scoring, 12-signal authenticity audit, headline impact matrix, content substance scoring, and a cheap-format MVP testing ladder. Use when the user needs content marketing, blog posts, email sequences, copywriting, video scripts, or says 'write content', 'blog post', 'email sequence', 'content calendar', 'marketing copy', 'video script', or 'hook'.
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Summarize a sprint's worth of Claude Code activity — sessions grouped by project (cwd), per-model cost breakdown, token efficiency (cache hit rate, compaction baselines), subagent effectiveness from workflow API, velocity metrics (turn_count, turn_duration_ms), and tool diversity across the sprint.
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Generate a daily standup summary from recent Claude Code sessions — completed work grouped by project (cwd), session costs from the pricing engine, tool invocations, error/compaction/APIError events, and turn velocity metrics from session metadata (turn_count, total_turn_duration_ms).
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Calculate a productivity score using actual Agent Monitor metrics — session completion rates, cache efficiency (cache_read vs input), compaction pressure (baseline tokens), turn velocity (turn_count / total_turn_duration_ms), tool success ratio (PreToolUse vs PostToolUse), and the workflow intelligence API's complexity and effectiveness scores.
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Generate a complete, deployable landing page from a brief. Produces a single self-contained HTML file with Tailwind CSS (via CDN), responsive design, dark mode, semantic HTML, and OG meta tags. Sections: hero with CTA, features, social proof, pricing (optional), FAQ, footer. Use when building a marketing page, product launch page, coming soon page, or any standalone landing page. Triggers: 'landing page', 'create a page', 'marketing page', 'launch page', 'coming soon page', 'one-page site'.
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When the user wants to plan or execute a rebrand—domain change, 301 redirects, migration, or announcement. Also use when the user mentions "rebranding," "rebrand," "domain change," "domain migration," "301 redirect," "change domain name," "rebrand announcement," "social media rebrand," "brand launch," or "domain redirect." For domain choice, use domain-selection.
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When the user wants to add, audit, implement, or optimize Twitter Card metadata for X link previews, including twitter:card, twitter:title, twitter:description, twitter:image, or X previews. For a full metadata lifecycle use page-metadata; for broader social previews use open-graph.
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When the user wants to plan, implement, or optimize employee-generated content (EGC) or employee advocacy. Also use when the user mentions "EGC," "employee advocacy," "employee content," "internal brand ambassadors," "employee social media," "employee advocacy program," "staff advocacy," "LinkedIn employee posts," or "brand ambassador program." For LinkedIn, use linkedin-posts.
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Make a short video about a product or brand (promo, launch, explainer, demo or social clip) entirely in code with Remotion, from idea to a rendered MP4 with sound. The owner approves the idea and a storyboard before anything is built.
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Use when making a trailer, cutscene, cinematic or short film in Unreal Engine 5.8 with Sequencer: shot lists, master and shot sequences, cameras, lenses, depth of field, camera cuts, spawnables, character animation in shots, per-shot lighting, Movie Render Graph or Movie Render Queue EXR renders, "render darker than the viewport", "first frames pop", "last frame missing", ACES or OCIO to DaVinci Resolve, the 180-degree rule, Sequencer Python, or reviewing a cut.
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Use when lighting or rendering in Maya with Arnold: a product hero shot, a character close-up or a sequence (master and shot lighting), key, fill and rim placement, "the Arnold render is noisy" or fireflies, render settings and time budgets, AOVs, light groups and EXRs for Nuke, OIDN or noice denoising, ACES or OCIO color, renders that look flat or too dark, Render Setup layers, batch or command-line renders, or judging a lit frame like a lighting supervisor.
日本語の概要は準備中です。原文の説明を表示しています。