Run immune pathway GSVA or ssGSEA analysis from a bulk expression matrix, a sample group file, and a local immune Reactome gene-set table, then export differential pathway results and a heatmap for two-group comparison.
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概要と使いどころ
Run immune pathway GSVA or ssGSEA analysis from a bulk expression matrix, a sample group file, and a local immune Reactome gene-set table, then export differential pathway results and a heatmap for two-group comparison.
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Use this skill to compute ESTIMATE immune-related microenvironment scores from a bulk expression matrix, generate an ESTIMATE score heatmap, and optionally generate group-wise ESTIMATE score boxplots plus significance tables when a sample group file is supplied. Trigger keywords: ESTIMATE, immune score, stromal score, tumor microenvironment score. NOT for: immune cell deconvolution, single-cell analysis, differential expression, clinical diagnosis.
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Use this skill to run GSVA or ssGSEA pathway-level differential analysis from a bulk expression matrix and a sample group file, then generate a heatmap from the saved GSVA result object. Trigger keywords: GSVA, ssGSEA, pathway enrichment, KEGG pathway analysis, MSigDB. NOT for: gene-level differential expression, single-cell analysis, methylation analysis, clinical diagnosis.
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Use when correcting batch effects in merged bulk expression matrices with sample-level batch metadata while preserving biological group structure and generating before-and-after QC plots. NOT for: single-cell integration, raw FASTQ processing, differential expression without batch labels, or datasets without biological groups.
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Use when identifying stable sample subtypes from bulk expression matrices with ConsensusClusterPlus, including PAC-based model selection and consensus matrix/CDF visualization. NOT for: differential expression analysis, single-cell clustering workflows, or non-expression tables.
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Recommend suitable prompts from 10,000+ Nano Banana Pro image generation prompts based on user needs. Optimized for Nano Banana Pro (Gemini), but prompts also work with Nano Banana 2, Seedream 5.0, GPT Image 1.5, Midjourney, DALL-E, Flux, Stable Diffusion, and any text-to-image AI model. Use this skill when users want to: - Generate images with AI (any model — Nano Banana Pro, Gemini, GPT Image, Seedream, etc.) - Find proven AI image generation prompts and prompt templates - Get prompt recommendations for specific use cases (portraits, products, social media, posters, etc.) - Create illustrations for articles, videos, podcasts, or marketing content - Browse a curated prompt library with sample images - Translate and understand prompt techniques Also available: "ai-image-prompts" skill — a model-agnostic version of this library for universal image generation.
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Apply when introducing a new internal API while old callers still exist. Migrate callers and delete the old API in the same wave instead of preserving compatibility layers.
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Spawn N parallel candidates at the same task, pick a base, graft the strongest parts of the losers into it. Use for /arena, 'arena this', 'throw it in the arena', or when one attempt at a non-trivial artifact would lock in the wrong shape.
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Apply when two or more fixes that share one premise have failed the same gate. Take a census of which actors hold the imbalance before the next fix, then question the premise instead of writing another fix that assumes it.
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Apply when you catch yourself writing the same instruction a second time, or notice a recurring correction. Encode the rule as a lint, metadata flag, runtime check, or script instead of more text.
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Apply when concurrent actors might write to the same file, branch, key, or state object. Eliminate the sharing first; serialize structurally only when one shared writer is a real invariant.
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Apply when designing commands, lifecycle steps, or processing loops that run amid crashes, restarts, and retries. Converge to the same end state regardless of partial prior runs.
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Automates pre-development workflow for large-scale complex tasks. Use when the user mentions "rewrite", "migrate", "overhaul", "refactor entire project", "transform", "rebuild in [language]", "spec-driven", or describes any large-scale project transformation that requires planning before coding. Also triggers on Chinese keywords: "改造", "重写", "迁移", "重构", "大规模", "规范驱动". Performs full project analysis, task decomposition, documentation generation, project-level instruction and native memory surface resolution, progress tracking setup, and then executes the plan within the same session.
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Model OR-Tools paired pickup-and-delivery routing problems, including PDPTW, dial-a-ride, paratransit, patient transport, and courier jobs with same-vehicle pairing, precedence, capacity, optional connected service, rider time windows, and vehicle shifts.
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Data conditioning techniques for gravitational wave detector data. Use when preprocessing raw detector strain data before matched filtering, including high-pass filtering, resampling, removing filter wraparound artifacts, and estimating power spectral density (PSD). Works with PyCBC TimeSeries data.
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Lomb-Scargle periodogram for finding periodic signals in unevenly sampled time series data. Use when analyzing light curves, radial velocity data, or any astronomical time series to detect periodic variations. Works for stellar rotation, pulsation, eclipsing binaries, and general periodic phenomena. Based on lightkurve library.
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Multi-hop evidence search + structured extraction over enterprise artifact datasets (docs/chats/meetings/PRs/URLs). Strong disambiguation to prevent cross-product leakage; returns JSON-ready entities plus evidence pointers.
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Generate ideas in one shot using creative sampling
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Expert startup business analyst specializing in market sizing, financial modeling, competitive analysis, and strategic planning for early-stage companies. Use PROACTIVELY when the user asks about market opportunity, TAM/SAM/SOM, financial projections, unit economics, competitive landscape, team planning, startup metrics, or business strategy for pre-seed through Series A startups.
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Generate comprehensive market opportunity analysis with TAM/SAM/SOM calculations
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Build and deploy the same feature consistently across web, mobile, and desktop platforms using API-first architecture and parallel implementation strategies.
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This skill should be used when the user asks to "calculate TAM", "determine SAM", "estimate SOM", "size the market", "calculate market opportunity", "what's the total addressable market", or requests market sizing analysis for a startup or business opportunity.
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Senior embedded software engineer specializing in firmware and driver development for ARM Cortex-M microcontrollers (Teensy, STM32, nRF52, SAMD). Decades of experience writing reliable, optimized, and maintainable embedded code with deep expertise in memory barriers, DMA/cache coherency, interrupt-driven I/O, and peripheral drivers.
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Führt AGB, Kundeninformationen und Bestelltexte zu einer konsistenten Endfassung zusammen. Prüft Einbeziehung, Versionierung und Bestandskundenänderung und bereitet die konkrete Umsetzung ohne eigenmächtige Veröffentlichung vor.
日本語の概要は準備中です。原文の説明を表示しています。