「sequence」の検索結果

Professional content generation system with a GSD-style phased workflow, integrated SEO optimization (claude-seo), and anti-AI auditing (humanizer). USE THIS SKILL whenever the user asks to write, draft, create, generate, or produce ANY content — including blog posts, articles, LinkedIn posts, Facebook posts, Twitter/X tweets or threads, Instagram captions, email newsletters, email campaigns or sequences, landing pages, product pages, web pages, sales pages, sales funnels, case studies, testimonials, product descriptions, or SEO metadata. Also triggers on: "/writer:discuss", "/writer:plan", "/writer:execute", "/writer:verify", "/writer:ship", "/writer:next", "/writer:profile-create", "/writer:profile-view", "/writer:profile-edit", "/writer:status", "/writer:help", "/writer:update" — or any request to manage a writer profile or create marketing materials. ALWAYS use this skill even for quick, casual content requests like "write me a LinkedIn post about X" or "draft a tweet thread." The profile and phased workflow produce significantly better output than ad-hoc generation.

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Architect a feature with the Carmack Council before writing code. Use when explicitly asked to plan a feature, do a "council plan", "carmack plan", or invoke /council-plan. Carmack's philosophy chairs a council of domain experts — Troy Hunt (security), Martin Fowler (refactoring), Kent C. Dodds (frontend), Matteo Collina (Node.js), Brandur Leach (Postgres), Vercel Performance, Simon Willison (LLM pipeline), Karri Saarinen (UI quality), Vitaly Friedman (UX quality). Interactive feature discovery followed by parallel subagent dispatch. Produces a sequenced, attributed implementation plan with no code. Stack: Next.js App Router / React / TypeScript / tRPC / Prisma / Neon / Clerk.

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Drive the ENTIRE tdmcp roadmap-to-1.0 to completion as a resumable, wave-by-wave campaign — Milestone 4 (generative-AI bridge wave), Milestone 5 (mixer scene arming), and the v1.0 consolidation gates G1–G6 — routing each class of work to the right existing sub-harness. Use whenever the user wants to "implement everything / all the milestones / the whole roadmap / finish the road to 1.0", run the next milestone, close the consolidation gates, or build a long autonomous campaign across M4/M5/G1–G6. ALSO use for every follow-up: continue/resume the roadmap campaign, run the next wave, re-run a failed wave, fold in QA results, check campaign status, re-prioritize, or scope to one milestone/gate. This is the CAMPAIGN layer ABOVE tdmcp-pipeline / tdmcp-feature-lead / tdmcp-backlog-campaign — it sequences across MULTIPLE sub-harnesses (tools, mixer, coverage, docs, bridge, recipes, submission), which the generic backlog-campaign does not. For a SINGLE feature use tdmcp-pipeline; for one tool-shaped backlog file use tdmcp-backlog-campaign. Simple questions can be answered directly.

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Pin a measurable, outcome-based Definition of Done for a diamond — a behaviour-change that creates value, not a build-list. Problem-first Socratic sequence; writes definition_of_done to the diamond at birth or retrofits it when missing.

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Use on any core for first-run planning intake — Phase 0 runs the vendored BMAD-METHOD planning shelf, shared by every core, and Phase 1 (mining `04-prd.md` into intent records plus the Add-ons/sync-and-remote-entities decision) is full-stack-app's and pwa-app's shared procedure — identical mechanics, a different decision at step 5/8. Phase 0 also defines compressed intake, the path a user's explicit "just build it" choice takes on full-stack-app, pwa-app, authored, and copywriting cores: one batched round of questions in place of the shelf, writing a thinned archive at the same paths so Phase 1 (or, on copywriting, that core's own mining step), `ux-planner`, and the Re-entry pass all keep their documented source. Also use for the Re-entry pass, which mines new scope into additional intents without re-running the shelf, on any core with a module axis to add an intent to (full-stack-app, pwa-app, authored) — landing-page has none, so its own new-scope path runs through `hedgehog-landing-loop`'s Correction Protocol instead. Invoked by the `planner` agent, which decides the path; don't run standalone. landing-page runs this skill's Phase 0 on first run, then mines the same archive through `hedgehog-landing-loop`'s own planning-intake section, that core's counterpart to this skill's Phase 1. copywriting runs this skill's Phase 0 the same way (full or compressed), then mines the same archive through `hedgehog-copywriting-loop`'s own planning-intake section into a what/audience/register brief — no module axis, so its own new-scope path runs through that loop's Correction Protocol rather than the Re-entry pass below. An authored core runs this skill's Phase 0, then `hedgehog-core-design`, then this skill's Phase 1 mining against the designed layer sequence. A brownfield adoption (`hedgehog-adopt`) never runs this skill's shelf at all — the drivers BMAD elicits are already settled facts of a repo that already exists.

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Provides Mermaid diagram syntax, best practices, and styling rules for technical visualizations. Use when creating diagrams, flowcharts, sequence diagrams, class diagrams, state diagrams, ER diagrams, architecture diagrams, C4 diagrams, or any visual documentation in markdown.

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Provides Mermaid diagram syntax, best practices, and styling rules for technical visualizations. Use when creating diagrams, flowcharts, sequence diagrams, class diagrams, state diagrams, ER diagrams, architecture diagrams, C4 diagrams, visualizations, or any visual documentation in markdown. Always use this skill when generating or updating Mermaid code blocks.

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Apply MCAF human-review-planning guidance for a large AI-generated code drop by reading the target area, tracing the natural user and system flows, identifying the riskiest boundaries, and prioritizing the files a human should inspect first. Use when the codebase is too large to review line-by-line and you need a practical review sequence plus a prioritized file list.

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Constructs accretion/dilution analysis with pro forma financials, synergy phasing, and purchase price allocation. Use when modeling merger outcomes, calculating EPS accretion, or analyzing deal structures.

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Evaluates key person clause triggers, consequences, and cure mechanics in partnership documentation. Use when analyzing key person provisions, assessing management stability risk, or structuring departure protections.

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D2 diagramming language reference for architecture diagrams, sequence diagrams, grid layouts, SQL tables, and class diagrams. Produces .d2 files rendered via CLI or playground.

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Render Mermaid diagrams as ASCII/Unicode art for terminal display or as SVG files. Use when visualizing flowcharts, state machines, sequence diagrams, class diagrams, or ER diagrams. Supports 17 themes (including vellum, tokyo-night, catppuccin, nord, dracula, github) plus custom colors via --colors JSON.

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Coordinate SEO, LLM-readable site architecture, UX, content, monitoring, security, and external authority work as a task-plan-driven sequence. Use this skill when the user asks to plan, execute, validate, or route multi-skill website growth work; asks what to do next across semantic core, URL structure, internal linking, schema, llms.txt, UX journeys, analytics, citation monitoring, or white-hat link placement; or wants a central architect that preserves evidence, alarms, handoffs, and tests.

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Use when uncertainty remains and the minimum useful sequence of questions should be asked.

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Specialized prompt-building methodology for content and communications tasks. Provides 11 tested approaches (3 identity, 4 reasoning, 4 output) for writing, editing, content strategy, copywriting, audience analysis, editorial evaluation, cross-channel adaptation, and persuasion design. Use when building a Claude prompt or system prompt for content creation, editorial workflows, or communications tasks. Trigger on: "build a prompt for writing," "prompt for content strategy," "prompt for copywriting," "prompt for blog posts," "prompt for email sequences," "system prompt for editorial," "prompt for messaging framework," "content brief prompt," "prompt for audience analysis," "prompt that produces better content." Do NOT use for writing content directly — this Skill builds prompts that produce better content. Do NOT use for evaluating or scoring existing prompts — use rootnode-prompt-validation if available. Do NOT use for general prompt compilation — use rootnode-prompt-compilation if available.

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Polish cut gemstones to final finish using progressive abrasive sequences. Covers pre-polish sanding, polishing compounds, lap selection, and quality assessment for both cabochons and faceted stones. Use when a cabochon or faceted stone has completed cutting and is ready for polishing, selecting the correct compound and lap for a specific species, troubleshooting a polish that will not reach full lustre (orange peel, haze, scratches), or re-polishing a stone with surface wear.

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Build sequential (stateful) logic circuits including latches, flip-flops, registers, counters, and finite state machines. Covers SR latch, D and JK flip-flops, binary/BCD/ring counters, and Mealy/Moore FSM design with clock signal and timing analysis. Use when a circuit must remember past inputs, count events, or implement a state-dependent control sequence.

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Number antibody variable domains, annotate CDRs, and assess developability from sequence. Use this skill to apply IMGT, Kabat, Chothia, Martin, or AHo numbering with ANARCI, delimit CDRs and framework regions, scan for chemical liabilities (N-glycosylation sequons, deamidation NG, isomerisation DG, oxidation, unpaired cysteine, fragmentation), compute pI, net charge, extinction coefficient and hydrophobicity, and plan humanisation by CDR grafting. Also trigger on antibody, nanobody, VHH, scFv, Fab, CDR, framework, ANARCI, abnumber, IgBLAST, OAS, SAbDab, humanization, Vernier residues, or developability.

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Access a collection of open-source molecular design and structural biology tools on the Tamarind Bio platform, via its REST API or MCP server — no local GPUs required. Tamarind bundles popular open-source models for structure prediction (AlphaFold, Boltz, Chai, ESMFold), protein, binder, and de novo design (RFdiffusion, ProteinMPNN, BoltzGen), antibody and nanobody design and developability, protein-ligand docking (DiffDock, Autodock Vina), binding-affinity prediction, MSA generation, and molecular dynamics. Use when the user mentions Tamarind or tamarind.bio, wants to run any of these open-source tools in the cloud, references app.tamarind.bio/api or the x-api-key header, or needs to submit batches of sequences for structural or biophysical characterization.

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DiffDock and DiffDock-L diffusion-based molecular docking. Use for blind protein-small-molecule pose prediction from a PDB file or sequence plus SMILES/SDF/MOL2, batch docking over a CSV of complexes, virtual screening triage, sampling multiple poses per complex, and reading the confidence score correctly. Also trigger on DiffDock, DiffDock-L, inference.py, confidence_model, samples_per_complex, ESM embedding preparation for docking, or blind docking without a defined box. Not for binding affinity prediction — the confidence score ranks pose plausibility, not potency.

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How to use the Adaptyv Bio Foundry API and Python SDK for protein experiment design, submission, and results retrieval. Use this skill whenever the user mentions Adaptyv, Foundry API, protein binding assays, protein screening experiments, BLI/SPR assays, thermostability assays, or wants to submit protein sequences for experimental characterization. Also trigger when code imports `adaptyv`, `adaptyv_sdk`, or `FoundryClient`, or references `foundry-api-public.adaptyvbio.com`.

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Design new proteins that bind a chosen surface, using BindCraft's AlphaFold2-guided hallucination or the RFdiffusion backbone plus ProteinMPNN sequence pipeline. Use this skill to specify a target epitope by hotspot residue, trim a receptor to the region worth designing against, set up a design campaign, and filter the output on the in-silico metrics that predict experimental success — interface predicted TM-score, predicted aligned error at the interface, buried surface area, and shape complementarity. Also trigger on BindCraft, RFdiffusion, ProteinMPNN, minibinder, hallucination, inverse folding, hotspot residue, epitope targeting, ipTM, or de novo binder.

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Design small interfering RNA and antisense oligonucleotide sequences against a transcript, and screen them for the failure modes specific to nucleic-acid drugs. Use this skill to tile a target transcript, apply positional and thermodynamic selection rules including duplex asymmetry and nearest-neighbour melting temperature, scan candidates for seed-region complementarity to off-target transcripts, and lay out a chemical modification pattern — gapmer architecture, 2'-O-methyl and 2'-MOE wings, locked nucleic acid, and phosphorothioate placement. Also trigger on siRNA, antisense oligonucleotide, ASO, gapmer, RNase H, seed region, duplex asymmetry, 2'-MOE, locked nucleic acid, phosphorothioate, or GalNAc conjugate.

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Analyze and engineer protein glycosylation. Scan sequences for canonical N-glycosylation sequons (N-X-S/T with X not proline, including overlapping sites), predict O-GalNAc hotspots, read glycan notation, and reach the curated external tooling (NetNGlyc, NetOGlyc, GlycoShield, GlycoWorkbench, GlyTouCan, GlyConnect). Use this skill for therapeutic antibody glycoengineering and afucosylation for ADCC, Fc glycan control, glycan shielding in vaccine immunogen design, sequon removal or insertion, and half-life engineering through sialylation. Also trigger on N-glycosylation, sequon, NXS/NXT, O-glycosylation, glycoform heterogeneity, afucosylation, high-mannose, GlyTouCan, or WURCS.

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