「main」の検索結果

Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CTCF-only/DNase-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.

日本語の概要は準備中です。原文の説明を表示しています。

Provides Event-Driven Architecture (EDA) patterns for Spring Boot — creates domain events, configures ApplicationEvent and @TransactionalEventListener, sets up Kafka producers and consumers, and implements the transactional outbox pattern for reliable distributed messaging. Use when implementing event-driven systems in Spring Boot, setting up async messaging with Kafka, publishing domain events from DDD aggregates, or needing reliable event publishing with the outbox pattern.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the project follows hexagonal (ports & adapters) architecture. Prevents domain code from depending on Spring or JPA. Use when you see packages like domain/, application/, infrastructure/, or adapters/ in the project structure.

日本語の概要は準備中です。原文の説明を表示しています。

Build and sharpen a project's domain model. Use when discussing codebase terminology, writing or editing a GLOSSARY.md, or recording or editing an ADR.

日本語の概要は準備中です。原文の説明を表示しています。

Extract structured domain knowledge from AI models in-session or from local open-source models via Ollama. No API key needed.

日本語の概要は準備中です。原文の説明を表示しています。

Master proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design to build maintainable, testable, and scalable systems.

日本語の概要は準備中です。原文の説明を表示しています。

Integrate Firebase Auth (authentication + domain restriction) into internal applications. Includes domain restriction via Blocking Functions and user registration to Firestore.

日本語の概要は準備中です。原文の説明を表示しています。

Triage GitHub issues by applying type, effort, priority, and area labels. Runs in an isolated context to avoid polluting the main conversation with issue details. Delegates to a specialized triage agent with label validation hooks.

日本語の概要は準備中です。原文の説明を表示しています。

Replicate and validate a GitHub issue by spinning up Archon, analyzing the issue, and systematically testing all described symptoms using browser automation. Use when: User wants to reproduce a bug, validate a GitHub issue, confirm a reported problem, or investigate whether an issue is real before working on a fix. Triggers: "replicate issue", "reproduce issue", "validate issue", "confirm bug", "test issue", "can you reproduce", "try to replicate", "verify the bug". Capability: Checks out main, pulls latest, starts Archon, reads the GitHub issue, then uses agent-browser to systematically test every symptom and produce a findings report. NOT for: Fixing issues (use /archon or /exp-piv-loop:fix-issue), general UI testing (use /validate-ui).

日本語の概要は準備中です。原文の説明を表示しています。

Operate and maintain OpenViking server - configure, install, start, stop, and cleanup the server. Use when need to setup or manage OpenViking service deployment.

日本語の概要は準備中です。原文の説明を表示しています。

Use when: User wants to extend Docker with custom tools, personalize the Docker environment, or set up user-specific Docker customization. Triggers: 'extend docker', 'docker-extend', 'add tools to docker', 'customize docker', 'add my tools to the container', 'personalize docker setup', 'docker user setup', 'install tools in docker'. Does: Interactively sets up Dockerfile.user and docker-compose.override.yml so users can add personal tools to their Docker environment without affecting maintainer files or committing user-specific config to git.

日本語の概要は準備中です。原文の説明を表示しています。

Core module implementation for claude-flow v3. Implements DDD domains, clean architecture patterns, dependency injection, and modular TypeScript codebase with comprehensive testing.

日本語の概要は準備中です。原文の説明を表示しています。

Domain-Driven Design architecture for claude-flow v3. Implements modular, bounded context architecture with clean separation of concerns and microkernel pattern.

日本語の概要は準備中です。原文の説明を表示しています。

Improve code structure, readability, and maintainability without changing external behavior through systematic refactoring techniques like extracting functions, removing duplication, simplifying conditionals, and applying design patterns. Use when reducing technical debt, extracting functions or classes, removing code duplication, simplifying complex conditionals, renaming for clarity, applying design patterns, improving code organization, reducing coupling, increasing cohesion, or maintaining test coverage during structural improvements.

日本語の概要は準備中です。原文の説明を表示しています。

Promote QA → production by opening a PR from peterdrier/Humans:main to nobodies-collective/Humans:main with a properly-qualified commit summary. Use when the user says "PR to production", "promote to prod", "PR from origin to upstream", "prod PR", or any variation of pushing batched fork changes upstream. Always use this skill for the two-remote promotion flow even if the user doesn't say "prod" explicitly.

日本語の概要は準備中です。原文の説明を表示しています。

Run an extremely strict maintainability review for abstraction quality, giant files, and spaghetti-condition growth. Use for a thermo-nuclear code quality review, thermonuclear review, deep code quality audit, or especially harsh maintainability review.

日本語の概要は準備中です。原文の説明を表示しています。

Refactor code to improve quality while maintaining functionality. Use when you need to improve code structure, eliminate duplication, optimize performance, or enhance maintainability without changing behavior.

日本語の概要は準備中です。原文の説明を表示しています。

Sets up an `## Agent skills` block in AGENTS.md/CLAUDE.md and `docs/agents/` so the engineering skills know this repo's issue tracker (GitHub or local markdown), triage label vocabulary, and domain doc layout. Run before first use of `to-issues`, `to-prd`, `triage`, `diagnose`, `tdd`, `improve-codebase-architecture`, or `zoom-out` — or if those skills appear to be missing context about the issue tracker, triage labels, or domain docs.

日本語の概要は準備中です。原文の説明を表示しています。

Sync delta specs from a change to main specs. Use when the user wants to update main specs with changes from a delta spec, without archiving the change.

日本語の概要は準備中です。原文の説明を表示しています。

Generates creative domain name ideas for your project and checks availability across multiple TLDs (.com, .io, .dev, .ai, etc.). Saves hours of brainstorming and manual checking.

日本語の概要は準備中です。原文の説明を表示しています。

Extract structured domain knowledge from AI models in-session or from local open-source models via Ollama. No API key needed.

日本語の概要は準備中です。原文の説明を表示しています。

Master proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design to build maintainable, testable, and scalable systems.

日本語の概要は準備中です。原文の説明を表示しています。

Plot per-gene mutation distributions on a protein-domain map (lollipop / needle plots) showing mutation position, recurrence count, and variant classification with maftools, g3-lollipop, trackViewer, and ProteinPaint. Use when visualizing recurrent mutation hotspots on a single gene's protein, marking domain boundaries from UniProt/Pfam, comparing missense vs truncating distributions, or contrasting two cohorts on the same lollipop.

日本語の概要は準備中です。原文の説明を表示しています。

Annotates ChIP-seq peaks to genomic features, nearest genes, ENCODE candidate cis-regulatory elements (cCREs), and regulatory domains. Uses ChIPseeker (R), HOMER annotatePeaks.pl (CLI), pyranges (Python), GREAT/rGREAT (regulatory domain gene-set enrichment), ChIP-Enrich (locus-length-adjusted), ENCODE SCREEN cCRE classification (PLS/pELS/dELS/CTCF-only/DNase-H3K4me3), and ENCODE-rE2G for cell-type-specific enhancer-gene linking. Handles nearest-TSS vs host-gene ambiguity, promoter window definition, and feature priority. Use when assigning genomic context to peaks, linking enhancer peaks to target genes, classifying peaks against ENCODE cCRE registry, or running gene-set enrichment on peak-associated genes.

日本語の概要は準備中です。原文の説明を表示しています。