5,305 件 ・ 関連度順
概要と使いどころ
Calls HLA class I and class II alleles at 2/4/6/8-field resolution from WGS/WES/RNA-seq/long-read data using OptiType, HLA-LA, T1K, Polysolver, HLA-HD, arcasHLA, StarPhase, or HIBAG imputation. Use when typing for HSCT, solid-organ transplant, neoantigen prediction, PGx screening (B*57:01, B*15:02, etc.), or disease-association studies, with reconciliation across tools and IPD-IMGT/HLA version mismatch handling.
日本語の概要は準備中です。原文の説明を表示しています。
Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS. Use when narrowing a GWAS lead SNP to a 95 percent credible set, choosing between in-sample and reference LD, calibrating non-sparse loci with SuSiE-inf or FINEMAP-inf, integrating functional priors via PolyFun, fine-mapping across ancestries with SuSiEx, diagnosing LD mismatch via estimate_s_rss and kriging_rss, handling HLA or long-range LD, or feeding credible sets into coloc.susie for colocalization.
日本語の概要は準備中です。原文の説明を表示しています。
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
日本語の概要は準備中です。原文の説明を表示しています。
Performs 3D shape-based similarity searching using ROCS (OpenEye), USRCAT (ultra-fast), Open3DAlign (RDKit), ESPSim (electrostatic), and ShaEP with explicit handling of Tanimoto-Combo (shape + color), shape vs ECFP4 complementarity, conformer-ensemble searching, alignment optimization, and scaffold hopping. Use when searching for shape-mimicking compounds with different scaffolds, identifying bioisosteric replacements, prospective scaffold hopping, or expanding hit series beyond 2D similarity.
日本語の概要は準備中です。原文の説明を表示しています。
Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.
日本語の概要は準備中です。原文の説明を表示しています。
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Plan and diagnose FIPA-style ontology-service interactions while keeping declared ontology relations, provider capability, and application authorization separate. NOT for treating an ontology mapping as provider authority or guaranteed interoperability.
日本語の概要は準備中です。原文の説明を表示しています。
Managing third-party dependencies — version pinning, security auditing, license compliance, update workflows, lockfile management, supply chain security. Activate on "npm audit", "dependabot", "renovate", "pin versions", "dependency update", "supply chain", "license compliance", "lockfile", "security advisory", "typosquatting", "SBOM". NOT for internal monorepo package management (use monorepo-management) or publishing your own packages to npm/PyPI.
日本語の概要は準備中です。原文の説明を表示しています。
Monitors a specified object against explicit stopping criteria and distinguishes replica convergence, iterative progress, and workflow terminal state. NOT for execution or setting goals.
日本語の概要は準備中です。原文の説明を表示しています。
Collage as a web design aesthetic — overlapping elements, mixed media, cut-out shapes, scrapbook layouts, and editorial magazine spreads adapted for the web. CSS techniques for layered compositions using z-index stacking, clip-path, mix-blend-mode, parallax layering, and grid-breaking layouts. Activate on 'collage web', 'editorial layout', 'magazine layout', 'overlapping elements', 'scrapbook', 'cut-out aesthetic', 'mixed media web', 'layered composition', 'grid-breaking', 'editorial web design', 'fashion website layout', 'David Carson'. NOT for photo collage/gallery grids (use collage-layout-expert), maximalist density (use maximalist-web-design), neobrutalism (use neobrutalist-web-designer).
日本語の概要は準備中です。原文の説明を表示しています。
Expert legal research agent for finding and scraping expungement data state by state. Knows authoritative sources, URL patterns, Firecrawl configuration, and 2026 legal landscape.
日本語の概要は準備中です。原文の説明を表示しています。
AI image generation for SEO assets: OG/social preview images, blog hero images, schema images, product photography, infographics. Powered by Gemini via nanobanana-mcp. Requires banana extension installed. Use when user says "generate image", "OG image", "social preview", "hero image", "blog image", "product photo", "infographic", "seo image", "create visual", "image-gen", "favicon", "schema image", "pinterest pin", "generate visual", "banner", or "thumbnail".
日本語の概要は準備中です。原文の説明を表示しています。
Full-site crawling, scraping, and site mapping via Firecrawl MCP. Use when user says "crawl site", "map site", "full crawl", "find all pages", "broken links", "site structure", "discover pages", "JS rendering", or needs site-wide analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Find and identify the velocity clamping branch inside CCSPlayer_MovementServices_FullWalkMove in CS2 binary using IDA Pro MCP, then generate a patch signature to disable it. Use this skill when reverse engineering CS2 server.dll or libserver.so to locate and patch the speed-clamp if-branch that caps player velocity to maxspeed inside FullWalkMove. Trigger: FullWalkMove speed clamp, velocity clamping patch, FullWalkMove SpeedClamp, disable maxspeed clamp
日本語の概要は準備中です。原文の説明を表示しています。
Guide the user through starting a new web application project — elicit requirements (MoSCoW scoping), create architecture and requirements documents, break work into tasks, and register them as a GitHub Project kanban board. Use when the user says "新しいWebアプリを作りたい", "Webアプリの立ち上げを手伝って", "start a new web app project", "プロジェクトの要件を整理したい", or "GitHub Projectにタスクを登録したい".
Consult Claude Code from Codex for a second opinion while Codex remains responsible for implementation and verification. Use when the user asks Codex to collaborate with Claude, consult Claude, ask Claude for a plan, get a Claude review, delegate analysis to Claude, or says "Claudeと一緒に", "Claudeに相談", "Claudeにレビューしてもらう", "Claudeの意見も聞く", or "Claudeと計画を立てる". Also use when an explicit independent planning or review pass from Claude would materially reduce risk on a complex coding task.
Layout structure for web interfaces, from grouping and alignment to reading order, progressive disclosure, and adaptive breakpoints. Use when structuring a page or component, spacing or aligning controls, deciding what collapses at small sizes, handling RTL layout direction, or reviewing frontend code for layout. Triggers on layout, spacing, alignment, grouping, negative space, whitespace, visual hierarchy, reading order, progressive disclosure, breakpoints, responsive layout, container queries, safe area, full-bleed, edge-to-edge, layout margins, RTL layout, logical properties.
日本語の概要は準備中です。原文の説明を表示しています。
Expert 3D modeling specialist with deep knowledge of topology, UV mapping, game-ready and film-ready pipelines, DCC tool workflows (Blender, Maya, ZBrush, 3ds Max, Houdini), retopology, LOD systems, and export pipelines. This skill represents years of production experience distilled into actionable guidance. Use when "3d model, 3d modeling, mesh topology, uv unwrap, uv mapping, retopology, retopo, low poly, high poly, subdivision, subdiv, edge flow, edge loops, polygon modeling, box modeling, hard surface, organic modeling, sculpting, zbrush, blender modeling, maya modeling, 3ds max, LOD, level of detail, game ready mesh, film ready, baking normals, high to low, fbx export, gltf export, texel density, 3d, modeling, topology, uv, game-dev, vfx, blender, maya, zbrush, retopology, lod, hard-surface, organic, sculpting" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
AVFoundation (AVPlayer / AVPlayerLayer / AVPlayerItemVideoOutput / AVAsset) の落とし穴・文書化されていない実装挙動・debugging チェックリストを集約した reference skill。Swift / Objective-C で AVPlayer を使った動画再生 / seek / scrub / frame stepping を実装・debug するときに発火。VLCKit ではなく **AVFoundation 系** の問題に特化。
Non-testing browser automation - web scraping, form filling, screenshot capture, PDF generation, workflow automation. For TESTING with Playwright, use e2e-playwright skill instead. Activates for web scraping, form automation, screenshot, PDF, headless browser, Puppeteer, Selenium, automation scripts, data extraction.
日本語の概要は準備中です。原文の説明を表示しています。
Adds debugging capabilities and troubleshoots Pine Script issues in TradingView's opaque environment. Use when scripts have errors, unexpected behavior, need debugging tools added, or require troubleshooting. Triggers on "debug", "fix", "error", "not working", "wrong values", or troubleshooting requests.
日本語の概要は準備中です。原文の説明を表示しています。
Optimizes Pine Script for performance, user experience, and visual appeal on TradingView. Use when improving script speed, reducing load time, enhancing UI, organizing inputs, improving colors and visuals, or making scripts more user-friendly. Triggers on "optimize", "improve", "faster", "better UX", "clean up", or enhancement requests.
日本語の概要は準備中です。原文の説明を表示しています。
Implements comprehensive backtesting capabilities for Pine Script indicators and strategies. Use when adding performance metrics, trade analysis, equity curves, win rates, drawdown tracking, or statistical validation. Triggers on "backtest", "performance", "metrics", "win rate", "drawdown", or testing requests.
日本語の概要は準備中です。原文の説明を表示しています。
Breaks down trading ideas into component parts for systematic Pine Script implementation. Use when analyzing trading concepts, decomposing strategies, planning indicator features, or extracting ideas from YouTube videos. Triggers on conceptual questions, "how would I build", YouTube URLs, or video analysis requests.
日本語の概要は準備中です。原文の説明を表示しています。