「cer」の検索結果

Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the gene-independent DNA-damage / G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

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Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

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TikTok creator campaigns and influencer marketing strategy. Creator discovery, outreach, ROI tracking, UGC strategy, and campaign management. Use when the user asks about TikTok influencer marketing, creator campaigns, influencer outreach, UGC content, or TikTok marketing partnerships.

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Ricerca giuridica su fonti italiane e UE: normativa, prassi e giurisprudenza in ogni materia (civile, penale, amministrativo, lavoro, tributario e specialistiche). Usare quando l'utente chiede di trovare, inquadrare o citare una norma ("cosa dice l'articolo...", "quale legge disciplina...", "è ancora in vigore...", "che estremi ha..."), cercare sentenze, massime o orientamenti, verificare la vigenza di una disposizione, verificare una citazione o l'esistenza di una pronuncia ("questa sentenza esiste?", "controlla le citazioni di questo atto"), cercare precedenti a favore e contro una tesi ("conformi e difformi", "sentenze pro e contro"), trovare un CCNL o le decisioni di ABF, ACF, AGCM o del Garante, creare un documento fondato su fonti (atti, pareri, clausole, contratti, memorie, diffide), o impostare una strategia processuale ("come imposto la causa", "come gestiresti questo caso", "conviene agire o transigere"), anche quando la fonte non è nominata. Non usare per domande non giuridiche.

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Godot Expert Analyst: Anara. Visionary project scoring and certification for Godot 4.7+ architecture. Use when evaluating project health, modernity, scalability, dependency graphs, or generating Visionary Certificates. Keywords: analyst, Anara, scoring, certification, architecture audit, ResourceLoader.get_dependencies, typed Dictionary, folder-by-feature, Visionary Certificate, Godot 4.7.

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Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the p53-dependent G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

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Sort grocery lists by aisle order using store aisle sign photos. Build aisle maps from uploaded images, match items to aisles, and output optimized shopping routes. Use when users upload aisle sign photos, request grocery list sorting, want shopping trip optimization, need store layout mapping, or mention grocery list organization.

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Produces requirement-by-requirement CRE insurance certificate compliance reviews by analyzing ACORD 25 certificates and endorsements against Access Agreement terms. Use when the user mentions COI review, insurance compliance, ACORD 25 analysis, Additional Insured verification, primary/non-contributory status, waiver of subrogation, vendor insurance audit, CGL compliance, umbrella follow-form, broker-ready deficiency instructions, certificate holder vs. additional insured, AI endorsements (CG 20 10, CG 20 37), or carrier rating checks.

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Use when working with the non-metallic engineering materials — polymers, ceramics, or composites — and you need to reason about structure, processing, or properties. Covers thermoplastics versus thermosets, chain structure, glass transition, and viscoelasticity in polymers; ionic and covalent bonding, sintering, brittleness, and Weibull statistics in ceramics; and fiber-reinforced laminates, matrix and reinforcement roles, the rule of mixtures, and anisotropy in composites. Reach for it to choose a plastic, understand why a ceramic fails, or predict the stiffness of a laminate.

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Evaluates master and special servicer performance with delinquency management, modification outcomes, and loss mitigation effectiveness. Use when assessing servicer quality, monitoring servicing metrics, or evaluating servicer transfers.

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Select an OCR/HTR engine by benchmarking candidates on the same labelled samples — source ground truth from open datasets (e.g. Hugging Face PAGE-XML corpora) or hand-transcription, wrap every engine behind a transcribe(image_path) -> str adapter (vision-LLMs via any OpenAI-compatible endpoint, dedicated HTR REST APIs, cloud OCR), and score with zero-dependency raw CER, lenient CER, WER, and a critical name/date token diff. Use when choosing an engine for handwriting or historical-document transcription, when published accuracy claims need honest verification on your own material, or when a records workflow must surface confident-but-wrong names and dates that a low aggregate CER hides.

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Detects insecure network communication in mobile apps (Android/iOS). Trigger on: cleartext HTTP, TLS misconfiguration, certificate pinning bypass, hostname verification disabled, allowCleartextTraffic, NSAllowsArbitraryLoads, ATS exceptions, custom TrustManager, ALLOW_ALL_HOSTNAME_VERIFIER, TLS 1.0/1.1, weak cipher suites, certificate pinning absent, Network Security Configuration, onReceivedSslError, SSLSocket, OkHttp, NSURL, URLSession, certificate transparency, HSTS, MITM. Covers MASVS-NETWORK-1 (TLS required) and MASVS-NETWORK-2 (certificate validation).

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AD Certificate Services attack playbook. Use when targeting misconfigured AD CS for privilege escalation via ESC1-ESC13 template abuse, NTLM relay to enrollment, CA officer abuse, and certificate-based persistence.

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Comprehensive social media operations for B2B SaaS brand building and engagement. Use this skill to develop LinkedIn strategy, decide whether to run a LinkedIn newsletter and how to scope it, capture consented registrations from LinkedIn Events, check LinkedIn Live eligibility, manage Twitter/X presence, create YouTube content, engage on Reddit communities, decide whether and how to answer on Quora, build community, develop influencer and creator partnerships, vet a creator before paying them, start or fix a B2B podcast, book podcast guests and guest appearances, judge whether a podcast is worth appearing on when you cannot audit its numbers, write show notes and transcripts, run social listening (what are people saying about us, share of voice, brand monitoring, validated sentiment, alert thresholds, routing signals to the right owner), and execute organic social campaigns. Also triggers on: LinkedIn, LinkedIn newsletter, LinkedIn Events, LinkedIn Live, event registration form, subscribe to our newsletter on LinkedIn, marketing consent checkbox, Notify Employees, Twitter/X, YouTube, Reddit, community, influencer, creator partnerships, influencer vetting, engagement rate, fake followers, engagement pods, FTC disclosure, sponsored post disclosure, media kit, social media strategy, organic social, employee advocacy, podcast, podcast strategy, podcast guesting, how do I know if this podcast has real listeners, the host says they get 50k downloads, is this podcast worth going on, podcast RSS feed research, IAB podcast measurement certification, Listen Score, Apple Podcasts reviews, show notes, audiogram, episode transcript, social media account access, who has admin on our LinkedIn page, the person who ran our social accounts left, locked out of our company account, social media offboarding, YouTube channel owner, Slack primary owner, social account MFA, social media approval workflow, pause all scheduled posts, social listening, what are people saying about us, brand monitoring, brand mentions, share of voice, social share of voice vs competitors, sentiment analysis, is our sentiment dashboard accurate, listening query, boolean query, mention alerts, spike alert, CrowdTangle replacement, Reddit API access, which platforms can our listening tool see, someone on Reddit asked for a tool like ours, comment mining, voice of customer from social.

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Family coordination engine. Use this skill whenever the user mentions meals, meal planning, groceries, weekly schedule, family logistics, kid activities, custody schedule, co-parent coordination, family dashboard, weekly briefing, weekly prep, "what's for dinner", school events, pickup/dropoff, babysitter, pediatric nutrition, grocery list, grocery cart, "load the cart", "load the carts", "bargain hunt", "find the deals", "compare prices", "price check", "smart split", "save money on groceries", family calendar review, or anything involving coordinating schedules and meals for a family. Also trigger when the user says "parent helper", "family mode", "week ahead", or "plan the week". Trigger on local event queries: "what's going on", "things to do", "events this weekend", "anything happening", "stuff to do", "what can we do with the kids", "family stuff this weekend". This skill is the central hub — if it touches the family schedule, the family's food, or local family-friendly events, it belongs here.

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Guides agents through a 6-step discovery process to design and deploy Google Cloud global external Application Load Balancers with Cloud CDN, Cloud Armor, and Service Extensions, mapping workload requirements to best-practice configurations. Use when: - Designing, configuring, or deploying a Google Cloud global external Application Load Balancer, Cloud CDN, Cloud Armor WAF, or Service Extensions. - Discovering existing Google Cloud resources (Cloud Storage, MIGs, GKE, Cloud Run) to use as backends. - Generating production-grade Terraform HCL or gcloud CLI scripts for global external Application Load Balancers. - Actuating deployments via Infrastructure Manager or bash scripts, including IAM pre-checks. - Detecting, analyzing, or reconciling configuration drift on deployed global external Application Load Balancers. Don't use for: - Non-Google Cloud load balancing or security configurations. - Purely regional or internal load balancing setups (unless part of a hybrid/failover global design).

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IPA注意喚起(2026-10-09)とJPCERT/CC AT-2026-0030に基づき、外部公開アプリ・利用外部サービス・保有データの緊急点検と、CSIRT/CERTの観点でのインシデント対応チェック（検知・封じ込め・根絶・復旧・報告・事後対応）を行いレポートを出力する。「公開アプリのセキュリティチェック」「IPAの注意喚起に沿って点検」「インシデント対応の初動確認」「CSIRT観点で点検」等で使用。

Find and rank influencers by niche, engagement, and authenticity using Xpoz. Searches Twitter, Instagram, and Reddit for active voices in any topic. Use when asked to "find influencers", "discover thought leaders", "who's talking about X", "influencer research", or "find KOLs".

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Drafts USMCA/NAFTA Certificates of Origin for preferential tariff treatment on US-Mexico-Canada goods. Verifies origin criteria, HS classifications, and regional value content. Use when preparing trade certificates, customs origin documentation, duty preference claims, or cross-border shipment certifications.

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Drafts a Petition for Writ of Certiorari to the U.S. Supreme Court under Rules 10, 13, 14, and 33. Enforces Rule 10 criteria (circuit splits, precedent conflicts, important federal questions), jurisdictional verification under 28 U.S.C. §§ 1254/1257, timeliness, document structure, and booklet formatting. Use when seeking discretionary Supreme Court review, filing a cert petition, or drafting a writ of certiorari.

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Generates appellate-brief TOC, TOA, and Certificate of Compliance with defensible word-count methodology. Triggers on TOC/TOA rebuilds, certificate of compliance drafting, FRAP 32(g) compliance, word-count certification, or final brief formatting before filing.

日本語の概要は準備中です。原文の説明を表示しています。

Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the gene-independent DNA-damage / G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

日本語の概要は準備中です。原文の説明を表示しています。

A Certificate Authority (CA) is the trust anchor in a PKI hierarchy, responsible for issuing, signing, and revoking digital certificates. This skill covers building a two-tier CA hierarchy (Root CA +

日本語の概要は準備中です。原文の説明を表示しています。