「computational」の検索結果

Algorithmic philosophies are computational aesthetic movements that are then expressed through code. Output .md files (philosophy), .html files (interactive viewer), and .js files (generative algorithms).

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Think and work like an expert Computer Scientist. Use when a task calls for Computer Scientist judgment. Reasons from computational models, abstraction contracts, invariants, and measurable complexity through CLRS-grade algorithm analysis, impossibility results (FLP, CAP, NP-hardness), property-based and chaos testing, and formal tools (TLA+, Coq, Z3) while treating partial failure, race conditions, label leakage, and abstraction leaks like GC pauses and clock skew as first-class failure modes.

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Think and work like an expert Algebraist. Use when a task calls for Algebraist judgment. Reasons from carriers, operations, and morphisms through isomorphism theorems, universal properties, exact-sequence and homological tools (Ext, Tor, snake lemma), and computational systems like GAP, Magma, SageMath, and Lean while treating silently smuggled hypotheses (commutativity, units, Noetherian, algebraically closed base), characteristic-p false friends, and noncanonical isomorphisms as first-class failure modes.

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Think and work like an expert Astrophysicist. Use when a task calls for Astrophysicist judgment. Reasons like a senior astrophysicist across observational, computational, and multi-messenger work — from radiative transfer and error budgets through JWST/ALMA/Rubin/LIGO pipelines, VO archives, and calibrated detection vs upper-limit reporting.

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Detect and remove doublets from flow and mass cytometry data. Covers FSC/SSC gating and computational doublet detection methods. Use when filtering out cell aggregates before clustering or quantitative analysis.

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Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.

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Build interactive web applications using HTML/JavaScript interfaces with MATLAB computational backends via the uihtml component. Use when creating HTML-based MATLAB apps, JavaScript MATLAB interfaces, web UIs with MATLAB, interactive MATLAB GUIs, or when user mentions uihtml, HTML, JavaScript, web apps, or web interfaces.

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Infrastructure and practices for reproducible computational research. Covers environment management, data versioning, code documentation, and sharing protocols that enable others to reproduce your results. Use when ", " mentioned.

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Patterns for building, maintaining, and scaling bioinformatics workflows. Covers Nextflow, Snakemake, WDL/Cromwell, container orchestration, and best practices for reproducible computational biology. Use when ", " mentioned.

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Create a specification for an interactive scientific Datagrok application (simulation, ODE/PDE solver, computational tool)

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Understanding how digital systems actually work -- hardware, operating systems, networks, and information representation -- at a depth sufficient to reason about them rather than just use them. Covers CPU/RAM/storage/GPU roles, what an OS does, how packets travel the internet, and how computers represent numbers, text, images, and sound as binary. Use when a learner needs to build a mental model of computing rather than memorize menu paths.

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Compressive Vasomotion Hypothesis (CVH) — vasomotion as a fast compression sweep that collapses ambivalent neural resonances (the Bayesian-blur problem) into a definite state. Use when modeling the ~100ms taṇhā 'grab', precision-weighting as compression forcefulness, or the generative collapse step of vasocomputational active inference.

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Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.

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Nature-style materials science manuscript reviewer skill for testing materials design, synthesis, processing, structure-property, mechanism, stability, scalability, computational prediction and application claims against materials evidence chains.

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Comprehensive scientific research toolkit with 139 specialized skills for biology, chemistry, medicine, data science, and computational research. Transforms Claude into an AI research assistant with access to scientific databases, analysis tools, and domain-specific workflows.

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On-demand journal peer review simulation expert — supports 7 research paradigms (experimental/computational/empirical_survey/interpretive/mixed_methods/systematic_review/interdisciplinary) with 6-step review workflow, outputting targeted revision suggestions based on journal-specific review standards.

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Assume the role of Galyarder CTO (Chief Technology Officer). Technical guardian. Enforce technical integrity, architectural determinism, self-healing formal verification, and planetary computational leverage.

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Review computational protein or gene function predictions and fill PredictionReview YAML files using the COR/CNN/LSP/UNC/PLI/NPI/REP biological-validity taxonomy. Use for ProtNLM, DeepECTF, BioReason/GO-GPT, InterPro2GO, PANTHER/IBA, CLEAN, GloEC, MAPred, ProteinInfer, or other predicted EC/GO annotations, including audits of the evidence and reasoning in existing prediction reviews.

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Use when a task needs the judgment of a Bioinformatics Scientist — designing a differential-expression or GWAS analysis with correct multiple-testing correction, calling and triaging variants from NGS data using genotype-likelihood confidence rather than raw allele counts, interpreting a BLAST/DIAMOND homology search, choosing or building a genomics pipeline (aligner, caller, normalization method) for a specific data-generating process, or judging whether a computational-biology analysis's statistical design actually supports the biological claim being made. Distinct from a bioinformatics-technician (executes and QC-gates an established pipeline someone else designed) and a data-scientist (general product/experimentation judgment, not genomics-specific statistics) — this role owns which method and statistical model a genomics question requires, and why.

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Systematic drug repurposing — computational screening, evidence triangulation, and validation strategy.

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Practical computational and experimental chemistry workflows — cheminformatics, quantum chemistry, kinetics, and analytical methods.

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Computational mathematics expert for numerical solutions, approximations, error analysis, and scientific computing

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Scientific research engine with adversarial review, tree search, and serendipity detection. Use when: exploring hypotheses, validating findings against literature, running computational experiments with quality gates, or hunting for unexpected discoveries. Do NOT use for simple Q&A, code editing, or non-research tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.

日本語の概要は準備中です。原文の説明を表示しています。