「protocols」の検索結果

Builds clear, executable, and auditable inclusion and exclusion criteria for biomedical and clinical research protocols. Always use this skill when a user needs to translate a target population into operational screening rules tied to chart fields, time windows, tests, procedures, prior therapies, exclusions, and reviewable edge cases. Focus on protocol-stage precision, ambiguity reduction, auditability, and screening reproducibility rather than generic study design advice.

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Designs retrospective or prospective clinical cohort study protocols for biomedical and clinical research. Always use this skill when the user needs a cohort-based study plan rather than a general study idea, evidence summary, or mechanistic experiment design. Focus on cohort appropriateness, enrollment logic, baseline time-zero definition, follow-up structure, endpoint definition, variable collection, confounding control, and a coherent primary statistical analysis line. Do not invent data availability, follow-up completeness, outcome ascertainment quality, sample size adequacy, or causal interpretability.

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Use when evaluating platforms, marketplaces, and networks through a USV-style lens: network effects, defensibility, protocols, openness, and scalable distribution.

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Use when evaluating crypto protocols through a Paradigm-style research lens: mechanism design, protocol fundamentals, L2/MEV/incentives, and research-driven crypto investing.

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Provides database transaction concurrency-control background. Use when reasoning about transactions, commits and aborts, serializability, isolation anomalies, conflicts, dependencies, and protocol families such as locking, timestamp ordering, OCC, MVCC, SSI, TicToc, hybrid protocols.

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Multi-agent swarm formation and coordinated execution with topology-aware agent deployment, consensus protocols, and anti-drift enforcement.

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Master network protocol reverse engineering including packet analysis, protocol dissection, and custom protocol documentation. Use when analyzing network traffic, understanding proprietary protocols, or debugging network communication.

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Manages work transitions between team members or agents by creating structured handoff documents, summarizing project status, documenting key decisions, blockers, and open questions, and generating onboarding briefs. Use when someone needs to hand off, hand over, or transition a project; pass work to another person or agent; brief a colleague taking over; prepare a shift change summary; or onboard someone mid-task. Produces ready-to-use handoff documents covering current status, next steps, known issues, technical context, and communication templates for both planned and unplanned transfers.

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Use when strengthening AAMAS reproducibility evidence for interaction claims, including proofs and game definitions, opponent and population sets, self-play protocols, random seeds, compute, uncertainty on strategic outcomes, baselines, and consistency between what the paper claims about agents and what the artifact can actually show.

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Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.

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Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

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Apply modern Swift language patterns and idioms for non-concurrency, non-SwiftUI code. Covers if/switch expressions (Swift 5.9+), typed throws (Swift 6+), result builders, property wrappers, opaque and existential types (some vs any), guard patterns, Never type, Regex builders (Swift 5.7+), basic Codable shaping (CodingKeys, custom decoding, nested containers), modern collection APIs (count(where:), contains(where:), replacing()), basic FormatStyle usage, and string interpolation patterns. Use when writing core Swift code involving generics, protocols, enums, closures, or modern language features; route deep Codable to swift-codable, detailed formatting/localization to swift-formatstyle, and API naming to swift-api-design-guidelines.

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Use when setting up vehicle network communication in MATLAB using Vehicle Network Toolbox. Covers CAN/CAN FD (fully implemented), with architecture for J1939, XCP, and future protocols. Handles hardware discovery, channel creation, bus configuration, message exchange, signal encoding/decoding, and analysis across all supported vendors. (Vector, Kvaser, PEAK-System, NI, SocketCAN, MathWorks Virtual).

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Smart triggered RF capture on NI USRP radios with Wireless Testbench — record only when a signal of interest appears, not continuously (triggered spectrum sensing). Use energy detection to capture when signal power rises above the noise floor, or preamble detection to cross-correlate against a known sequence (WLAN L-LTF, 5G NR PSS/SSS, LTE PSS, Zadoff-Chu, custom protocols) and capture only when that protocol's preamble is detected. Use when implementing triggered (wake-on-signal) capture or spectrum sensing, capturing protocol-based signals via cross-correlation, calibrating detection thresholds (plotDetectionSignals / plotThreshold), scanning frequency bands for activity, or building transmit-then-detect workflows.

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Design AI agent communication protocols: MCP tool schemas, A2A, function calling, and inter- agent messaging. Use when building multi-agent systems, defining tool interfaces, or implementing agent-to-agent communication.

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Design multi-agent orchestration with workflow DAGs, routing, handoff protocols, and state management. Use when building pipelines of specialized agents, designing fan-out/fan-in patterns, or implementing fault-tolerant workflows.

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Analyze digital and analog captures from Saleae Logic MSO devices. Decode protocols like UART, SPI, I2C from exported binary files. Use when analyzing logic analyzer captures for CTF challenges, hardware reverse engineering, or protocol decoding.

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Generate a coaching conversation guide with questions, protocols, and follow-up actions for a teaching focus. Use when preparing for coaching sessions, mentoring, or peer feedback conversations.

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Select and configure a structured discussion protocol matched to the purpose, topic, and group readiness. Use when planning classroom discussions, Socratic seminars, or structured debate.

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Generate protocol/interface test suites that any implementation must pass. Define the contract once, test every implementation. Use when designing protocols or swapping implementations.

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Generate clinical trial protocols for medical devices or drugs. This skill should be used when users say "Create a clinical trial protocol", "Generate protocol for [device/drug]", "Help me design a clinical study", "Research similar trials for [intervention]", or when developing FDA submission documentation for investigational products.

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Tool safety protocols, adversarial output validation, error recovery patterns, and I/O contracts for research operations

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Cross-agent collaboration protocols, workflow handoff patterns, and commit message formats for TDD/Mikado/refactoring workflows

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Use for authorized reverse engineering of custom binary protocols, Protobuf/gRPC, WebSocket frames, and PCAP-driven protocol recovery.

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