Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/HPClaw☆ 32026年10月11日 更新
在Python 2.7环境下解析Windows目录链接(Junction)或符号链接的真实物理路径。提供基于PyWin32 API和PyQt4/5 QProcess调用cmd命令的两种解决方案,解决os.path.realpath失效及输出解析问题。
日本語の概要は準備中です。原文の説明を表示しています。
David-Li0406/meta-skill-evloving☆ 22026年7月14日 更新
PythonアプリをWindows向けに配布するため、Nuitkaでのコンパイル、不要ファイルやDLLの分析、Inno Setupでの軽量なインストーラー作成を支援します。
- PythonアプリのWindows配布
- 配布容量の大きな依存関係を調べたいとき
- 新しいWindows環境での起動不良調査
affaan-m/ECC☆ 27.8万2026年10月12日 更新
Pharmacokinetic and pharmacodynamic modelling and simulation - non-compartmental analysis, compartmental and population PK, PK/PD and exposure-response, TMDD, PBPK orientation, bioequivalence, allometric scaling and first-in-human dose, drug interaction prediction, and Bayesian therapeutic drug monitoring. Use when analysing concentration-time data, deriving exposure metrics, fitting PK or PD models, or evaluating dosing regimens. Triggers include "pharmacokinetics", "pharmacodynamics", "PK/PD", "NCA", "non-compartmental", "AUC", "Cmax", "lambda z", "half-life", "clearance", "volume of distribution", "compartmental model", "population PK", "popPK", "NONMEM", "nlmixr2", "Pharmpy", "Monolix", "exposure-response", "Emax", "EC50", "indirect response", "effect compartment", "TMDD", "PBPK", "bioequivalence", "RSABE", "ABEL", "allometric scaling", "first-in-human", "MABEL", "drug-drug interaction", "DDI", "ICH M12", "concentration-QTc", "therapeutic drug monitoring", "MIPD", and "dosing regimen".
日本語の概要は準備中です。原文の説明を表示しています。
K-Dense-AI/scientific-agent-skills☆ 4.9万2026年10月12日 更新
Zoom Video SDK for Linux - C++ headless bots, raw audio/video capture/injection, Qt/GTK integration, Docker support
日本語の概要は準備中です。原文の説明を表示しています。
anthropics/knowledge-work-plugins☆ 2.9万2026年10月12日 更新
Mentor for embedded and IoT hardware projects. Helps select MCUs, dev boards, and toolchains, decides where sensor readings end up (phone, PC, dashboard, or alert), and gives time/cost estimates and a phased build plan from breadboard MVP to production PCB. Use when the user mentions embedded, IoT, microcontroller, ESP32, STM32, Arduino, Raspberry Pi Pico, firmware, PCB, KiCad, EasyEDA, PlatformIO, MQTT, Home Assistant, ESPHome, Grafana, an IoT dashboard, seeing sensor data on a phone, or asks for hardware tool recommendations, project planning, or cost/time estimates for an electronics project.
日本語の概要は準備中です。原文の説明を表示しています。
alirezarezvani/claude-skills☆ 2.8万2026年8月30日 更新
Resolve "thisQuarter" to a concrete ISO date range relative to your run time — this quarter so far (quarter start → today). Returns inclusive civil dates plus exact UTC instants so you have temporal context without computing dates by hand. Read-only: no writes, no network. Use before a quarter-to-date task (QTD metrics, "this quarter").
日本語の概要は準備中です。原文の説明を表示しています。
HarnessMD/munder-difflin☆ 8,7272026年10月13日 更新
IoT and embedded device security testing methodology. Covers hardware reconnaissance (UART, JTAG, SWD, SPI flash, I2C EEPROM, eMMC chip-off), firmware acquisition (vendor portals, OTA capture, flash dump, binwalk extraction), firmware analysis (filesystem mounting, binary triage, hardcoded secrets, default credential discovery), bootloader attacks (U-Boot console, secure-boot bypass, fault injection), runtime attacks on embedded Linux/RTOS (busybox CVEs, MTD writes, /dev/mem), wireless protocol attacks (Zigbee, BLE, Z-Wave, LoRaWAN, Thread/Matter, sub-GHz), MQTT/CoAP/Modbus/BACnet/OPC-UA exploitation, mobile companion app analysis, cloud-IoT API abuse, and side-channel/glitching basics. Use for IoT pentest, smart-home assessment, ICS/OT testing, or embedded vulnerability research.
日本語の概要は準備中です。原文の説明を表示しています。
SnailSploit/Claude-Red☆ 7,4722026年10月13日 更新
Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO -> GWAS -> coordinates -> Open Targets L2G/coloc -> eQTL -> burden/coding context), with reproducible tables and optional figures. Use when a user provides a trait/EFO term and/or lead variants and needs locus-to-gene prioritization for downstream biology decisions.
日本語の概要は準備中です。原文の説明を表示しています。
openai/plugins☆ 7,4302026年10月8日 更新
音频可视化视频:把纯音频(播客片段、音乐、口播金句、电台)渲染成带动态波形/频谱的视频,配封面和标题,好发到抖音/B站/视频号等只收视频的平台。当用户说 音频可视化、音频转视频、播客做成视频、音频波形视频、音乐可视化、给音频配画面、声波视频、频谱视频、把音频发到视频平台、电台切片视频 时使用。基于 shared/scripts/audio_viz.py(ffmpeg showwaves/showcqt/showspectrum)。与 audio-mix 区别:那个输出音频,本 SKILL 输出视频;与 slideshow-video 区别:那个用图片,本 SKILL 用音频驱动画面。
日本語の概要は準備中です。原文の説明を表示しています。
ZJU-REAL/Easel☆ 3,5652026年10月12日 更新
Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-diseased tissue sites.
日本語の概要は準備中です。原文の説明を表示しています。
google-deepmind/science-skills☆ 3,2472026年10月10日 更新
Provides comprehensive code review guidance for React 19, Vue 3, Angular 17+, Svelte 5, Rust, TypeScript, Java, Java 8, PHP, Ruby, Rails, Python, Django, FastAPI, Go, C#/.NET, Kotlin, Swift, Dart, Flutter, NestJS, C/C++, Zig, CSS/Less/Sass, Qt, and more. Covers architecture review, performance review, security audit, code quality anti-patterns, and common bugs across all ecosystems. Use when: reviewing pull requests, conducting PR reviews, code review, reviewing code changes, establishing review standards, mentoring developers, architecture reviews, security audits, performance reviews, checking code quality, finding bugs, giving feedback on code.
日本語の概要は準備中です。原文の説明を表示しています。
awesome-skills/code-review-skill☆ 2,0942026年9月9日 更新
Verify whether a proposed XQUIC bug issue is real by checking the cited RFC or Internet-Draft mechanism against the repository's actual source behavior, tracing any root cause to current file and line evidence, and returning a fail-closed boolean gate. Use when validating an issue draft, investigating a claimed QUIC, HTTP/3, QPACK, or MoQT protocol violation, or before issue-submit may publish an issue.
日本語の概要は準備中です。原文の説明を表示しています。
alibaba/xquic☆ 1,9222026年10月9日 更新
Use only after explicit Codex `$superloopy:superloopy-frontend` or Claude Code `/superloopy:superloopy-frontend` invocation for supported screen-based application UI across browser-hosted Web, interactive deployed content-led Web, desktop, mobile/tablet, embedded/hybrid, Qt, custom-rendered, or mixed targets, such a task started with a leading `loopy` or `루피`, or an active Superloopy loop explicitly routing it here. Do not activate from UI, frontend, desktop, mobile, or framework vocabulary alone, or for TV, wearable, XR, automotive, game UI, TUI, static media/document artifacts, or non-UI work.
日本語の概要は準備中です。原文の説明を表示しています。
hashgraph-online/awesome-codex-plugins☆ 1,2932026年10月13日 更新
Build Manhattan, Miami, QQ, and locuszoom-style regional plots from GWAS, TWAS, PWAS, and QTL summary statistics with correct genomic-inflation diagnostics, multi-trait overlays, lead-SNP labeling, and LD-aware regional rendering. Use when visualizing association results across the genome, comparing two traits, computing genomic inflation lambda, or zooming into a locus with LD coloring.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Performs gene-level association from GWAS summary statistics via genetically predicted tissue expression using FUSION, PrediXcan, S-PrediXcan, S-MultiXcan, UTMOST, MOSTWAS, kTWAS, EpiXcan, TIGAR-V2, and probabilistic fine-mapping with FOCUS and MA-FOCUS. Use when running TWAS from GWAS sumstats, prioritising candidate causal genes from a GWAS lead locus, picking single-tissue vs cross-tissue models, identifying LD-induced TWAS false positives, choosing ancestry-matched prediction weights, fine-mapping co-regulated TWAS hits, or triangulating TWAS with cis-eQTL Mendelian randomization and colocalization to nominate a causal gene.
日本語の概要は準備中です。原文の説明を表示しています。
GPTomics/bioSkills☆ 1,2192026年8月15日 更新
Build industrial-grade SCADA/HMI dashboards in MATLAB following industrial-HMI conventions (ISA-101-aligned): gray-field philosophy, alarms at source, write safeguards, fixed-range trends, drill-down layout. Produces a real App Designer app (.mlapp, or plain-text .m+.xml on R2026b+) by handing serialization to the matlab-build-app skill when available, and falls back to a programmatic .m app otherwise. Use when wrapping OPC UA / Modbus / MQTT / OSI PI / PI AF monitoring scripts into a live operator app, building plant overviews, designing operator dashboards, or any time a user asks for a "SCADA dashboard", "HMI", "plant dashboard", "operator screen", or "industrial monitoring app" in MATLAB. Trigger on: SCADA, HMI, industrial dashboard, plant overview, operator screen, uigauge, uilamp, alarm banner, gray-field, ISA-101, OPC UA dashboard, setpoint, write safeguards, alarm visualization, OSIsoft PI, AVEVA PI, PI Server, PI Data Archive, PI AF, PI Asset Framework, piclient, afclient.
日本語の概要は準備中です。原文の説明を表示しています。
matlab/matlab-agentic-toolkit☆ 1,1572026年10月9日 更新
Manage Home Assistant configuration safely and fast — edit and deploy YAML (automations, blueprints, scripts, scenes, templates, MQTT), validate with ha core check, deploy via git or rapid scp, reload-vs-restart correctly, verify changes from logs, traces and entity state, and build Lovelace dashboards. Use for any Home Assistant config, automation, template, or dashboard work over SSH/hass-cli/MCP.
日本語の概要は準備中です。原文の説明を表示しています。
komal-SkyNET/claude-skill-homeassistant☆ 9682026年7月5日 更新
Expertise complète en droit français des étrangers, de l'asile et de la nationalité — entrée et visas, séjour (CESEDA livre IV, AES, étranger malade, regroupement familial, métiers en tension), éloignement et contentieux (OQTF, IRTF, rétention, référés, TA/CAA/CE), asile (OFPRA, CNDA, Dublin, CMA/ADA), nationalité et droits sociaux des étrangers (AME, PUMa, RSA, AAH, ASPA). Interroge en priorité trois connecteurs MCP complémentaires — OpenLegi (textes, jurisprudence administrative), LibreJustice (recherche sémantique tous ordres) et Legal Data Hunter (rétention/JLD, graphe de citations, statut de validité) — puis les sources officielles (Légifrance, ANEF, OFPRA, CNDA) et la doctrine associative (GISTI, Cimade, ADDE, Comede, Anafé). Déclencher dès qu'une question porte sur un étranger en France, même sans vocabulaire juridique — « papier de la préfecture », « récépissé périmé », « la CAF refuse le RSA » — et pour toute consultation, recours, note ou vérification de références dans ces matières.
日本語の概要は準備中です。原文の説明を表示しています。
lawve-ai/awesome-legal-skills☆ 8632026年10月3日 更新
Expert knowledge for Azure Web PubSub development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when building WebSocket/MQTT apps, using Socket.IO, configuring event routing, geo-replication, or chat workloads, and other Azure Web PubSub related development tasks. Not for Azure SignalR Service (use azure-signalr-service), Azure Event Hubs (use azure-event-hubs), Azure Service Bus (use azure-service-bus).
日本語の概要は準備中です。原文の説明を表示しています。
MicrosoftDocs/Agent-Skills☆ 7792026年10月11日 更新
Expert knowledge for Azure IoT Operations development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when configuring MQTT/OPC UA data flows, WASM/ONNX processing, Dapr/Fabric RT endpoints, or Arc Kubernetes deployments, and other Azure IoT Operations related development tasks. Not for Azure IoT (use azure-iot), Azure IoT Hub (use azure-iot-hub), Azure IoT Edge (use azure-iot-edge), Azure IoT Central (use azure-iot-central).
日本語の概要は準備中です。原文の説明を表示しています。
MicrosoftDocs/Agent-Skills☆ 7792026年10月11日 更新
Expert knowledge for Azure IoT Hub development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when configuring IoT Hub/DPS routing, device twins, MQTT/AMQP clients, Device Update, or Cosmos DB event storage, and other Azure IoT Hub related development tasks. Not for Azure IoT (use azure-iot), Azure IoT Central (use azure-iot-central), Azure IoT Edge (use azure-iot-edge), Azure IoT Operations (use azure-iot-operations).
日本語の概要は準備中です。原文の説明を表示しています。
MicrosoftDocs/Agent-Skills☆ 7792026年10月11日 更新