「replicate」の検索結果

ATAC-seq library quality control -- TSS enrichment, FRiP, fragment-size periodicity, library complexity (NRF/PBC1/PBC2), mitochondrial fraction, and ENCODE 4 thresholds. Use when assessing whether an ATAC-seq library passes ENCODE acceptance criteria, diagnosing transposition artefacts, comparing Omni-ATAC vs standard prep quality, or selecting which replicates to drop before peak calling.

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Call accessible chromatin regions from ATAC-seq BAM files using MACS3, MACS2, Genrich, or HMMRATAC. Use when identifying open chromatin from aligned ATAC-seq, choosing between point-source vs HMM peak callers, applying ENCODE-style pseudoreplicate IDR, removing blacklist regions, or fixing 501bp consensus peaks for downstream differential analysis.

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Build a differential-ready consensus peakset from per-replicate ATAC-seq peaks using iterative overlap removal, fixed-width re-centering, and majority-rule overlap. Use when generating a stable peak coordinate system for downstream differential accessibility, ML feature engineering, cross-sample comparison, or fixed-width peak counts; covers Corces 2018 iterative overlap (501 bp), DiffBind summit re-centering, and ENCODE consistency rules.

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Create premium hand-drawn architecture and process diagrams in the Lanshu animated GIF style, with editable .excalidraw files, static PNG previews, and genuinely animated GIFs with moving flow highlights. Use this skill whenever the user asks for 岚叔动态架构图, Excalidraw-like diagrams, DailyDoseOfDS-style black-background sketches, animated architecture/process GIFs, polished flowcharts, visual explanations of articles or system designs, or asks to replicate or improve a reference diagram with hand-drawn animated effects.

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Analyze images, video, speech, motion, products, and websites; route local vision, audio, depth, tracking, matting, identity, and restoration models; auto-edit, replicate, enhance, caption, voice, assemble, annotate, validate, and export editable Timeline Studio projects and videos. Use for reference-video remakes, filter and repeated-shot reconstruction, subject-aware reframing, clip splitting, source-time speed curves, Color Wheels grading, ramps and holds, person or product cutout, person or object outline, authorized face swap, shot and timing reconstruction, timeline markers, chapters, beat cues, review notes and ranges, supplied or web-sourced footage, AI video platform selection, cleanup, highlights, product promotion, website walkthroughs, image-to-video assisted edits, optical-flow editing, depth-assisted relighting, grayscale depth-video conversion, depth/2.5D/transition finishing, AI voiceover, subtitles, short-form production, .timeline automation, or editor evaluation.

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Systematic 3D interaction calls and differential analysis for Hi-C and HiChIP. The HiC-DC+ (Hi-C/HiChIP direct caller plus) package enables principled statistical analysis of Hi-C and HiChIP data sets – including calling significant interactions within a single experiment and performing differential analysis between conditions given replicate experiments – to facilitate global integrative studies. HiC-DC+ estimates significant interactions in a Hi-C or HiChIP experiment directly from the raw con

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Write a publication-ready article in one of three angles - a trending long-form piece, a watched-repo thesis, or a project-through-a-lens essay. Optional Replicate hero image with --visual.

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Reverse-engineer raw materials (Sparse idea, Dense idea, experimental log) from an existing AI research paper to build a benchmark case for evaluating paper-writing pipelines. Replicates the PaperWritingBench dataset construction procedure from arXiv:2604.05018 §3 / App. C. TRIGGER when the user asks to "build a benchmark case from this paper", "reverse-engineer raw materials", or "evaluate my pipeline against PaperWritingBench".

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Use when the next period content plan must be built from last period DATA — keep and replicate winners, cut losers, at most two new hypotheses, a 70/20/10 mix, a four-week overview, and an owner per slot. Trigger on 'next content plan', 'content plan for next month', 'plan from the audit', 'what should we post next quarter', 'scale what worked', 'plan content using the numbers'. Also use when a report just landed and the user asks what to do with it. Not for — auditing the past period first, see `39-content-audit-global`; turning the plan into a dated calendar, see `01-content-calendar-global`; the next period ADS plan, see `57-next-ads-plan-global`.

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AI image generation with OpenAI, Google, DashScope and Replicate APIs. Supports text-to-image, reference images, aspect ratios. Sequential by default; parallel generation available on request. Use when user asks to generate, create, or draw images.

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Clone any website into a pixel-perfect single-file HTML prototype. Extracts design tokens, assets, CSS computed styles, interaction patterns, and content via Playwright. Outputs a self-contained HTML file with real data injection. Use when the user wants to clone, replicate, reverse-engineer, or create a pixel-perfect copy of any website or web app. Provide one or more target URLs as arguments.

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Reverse-engineer and clone a website in one shot — extracts assets, CSS, and content section-by-section and proactively dispatches parallel builder agents in worktrees as it goes. Use this whenever the user wants to clone, replicate, rebuild, reverse-engineer, or copy any website. Also triggers on phrases like "make a copy of this site", "rebuild this page", "pixel-perfect clone". Provide the target URL as an argument.

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Designs, sanity-checks and reads out product experiments (A/B tests, holdouts, pre/post, geo and incrementality tests) and produces an experiment brief plus a readout with a ship / hold / replicate call. Use when you ask 'should we A/B test this', 'how long should the test run', 'is this result real', 'sample size', 'stat sig', 'SRM', 'holdout', 'our win rate is low', or need to grade an existing test plan or readout. Draws on 191 insights from 71 Lenny's Podcast guests, led by Ronny Kohavi, Ramesh Johari and Archie Abrams.

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End-to-end paper reproduction from arxiv URL through smoke runs to replication experiments. Handles missing or partial official code, missing training scripts, missing hyperparameters, and private datasets via similar-public-dataset substitution. Use when the user asks to reproduce, implement, replicate, or re-run a paper from scratch, or pastes an arxiv URL with reproduction intent.

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Cancer Research (AACR) figures: resolution (300-1200 DPI), formats (EPS/TIFF/AI), hierarchical panel labels (Ai, Aii, Bi), figure/table limits, legend requirements with replicate counts.

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Use when applying a published cohort study's methodology to a different database. Extracts the design from the source paper, maps variables to the target database with a harmonization table, generates the analysis code and reports every forced deviation.

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Publication-figure overlay for draw.io. Use instead of drawio whenever the diagram is for a paper, thesis, dissertation, journal, conference, IEEE/ACM submission, manuscript, camera-ready, Word/LaTeX figure, or other publication. Applies venue, figure-type, color, caption/legend, formula, and paper-readability gates for architecture, workflow, roadmap, network-topology, and replicated paper figures.

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Create, edit, replicate, import, and export draw.io diagrams with an offline YAML-first workflow: architecture, network topologies, flowcharts, UML/ER, org charts, Mermaid/CSV conversion, existing .drawio bundles, style presets, themes, and non-publication formula diagrams. For publication figures (paper, thesis, IEEE, camera-ready) use drawio-academic-skills instead.

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Convert image references into spatial hypotheses, camera constraints, construction routes, material evidence, and measurable Blender reconstruction gates. Use whenever a user asks to replicate, recreate, match, clone, or reconstruct a scene, environment, object, material, lighting setup, or shot from one or more images, especially when room connectivity, hidden space, perspective, visible-frame fidelity, material identity, aging, wetness, or photographic treatment matters.

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Extract the design of a screenshot, website URL or Figma file into a design.md with tokens, components, layout and brand rules, or copy one element (navbar, card, illustration) into an element.md with a rebuild or image-generation prompt. Use when the user wants to document, replicate, audit or reverse-engineer a visual design: its design system, palette, typography or style.

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Compare evaluated runs in a retort experiment along factor dimensions. Surfaces effects of each factor, aggregates across replicates, and highlights cells that diverge qualitatively — complementing (not replacing) retort's ANOVA analysis.

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Think and work like an expert Molecular Biologist. Use when a task calls for Molecular Biologist judgment. Reasons from central-dogma sequence flow, binding affinity (Kd/Km/kcat), gene regulation, and biological-versus-technical replicate structure through MIQE-compliant RT-qPCR, ddPCR, Western/flow/microscopy, CRISPR editing with rescue, and IWGAV antibody validation while treating off-target reagent effects, batch effects, mycoplasma and cell-line misidentification, and toxicity-driven artifacts as first-class failure modes.

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Think and work like an expert Crop Scientist. Use when a task calls for Crop Scientist judgment. Reasons from genotype-by-environment-by-management interaction, yield-component partitioning, and phenology-gated critical periods through MET stability analysis (AMMI, Finlay-Wilkinson, GGE biplots), mixed models (ASReml-R, lme4), N-response curves (quadratic-plateau, MRTN), and crop models (APSIM, DSSAT) while treating pseudo-replicated subsamples, single-site yield champions, uncorrected harvest moisture, and weather-during-anthesis confounding as first-class failure modes.

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Think and work like an expert Community Ecologist. Use when a task calls for Community Ecologist judgment. Reasons from Vellend's four processes and Chesson stabilizing/equalizing coexistence through PERMANOVA/betadisper, betapart turnover–nestedness, Gotelli SIM9/C-score null models, and vegan/entropart/picante pipelines while treating compositional closure, dispersion heterogeneity, and pseudoreplicated quadrats as first-class failure modes.

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