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概要と使いどころ
Drive the AADInternals PowerShell toolkit to perform Microsoft Entra ID tenant reconnaissance, access-token acquisition across Microsoft APIs, and federation/AD FS backdoor testing (Golden SAML, T1606.002) for defensive validation. Use during an authorized Entra ID/Microsoft 365 red-team assessment to map external attack surface or verify AD FS signing certs resist Golden SAML.
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Classical end-to-end empirical analysis workflow in the modern tidyverse + econometrics R ecosystem — dplyr + tidyr + haven + fixest + sandwich + lmtest + clubSandwich + AER + ivreg + did + bacondecomp + HonestDiD + eventstudyr + rdrobust + rddensity + Synth + gsynth + synthdid + MatchIt + WeightIt + cobalt + ebal + grf + DoubleML + mediation + marginaleffects + modelsummary + kableExtra + gt + ggplot2 + ggpubr + cowplot + binsreg. **Defaults to economics empirical-paper style** (AER / QJE / AEJ) — every run produces a publication-ready output set with a multi-column regression table (M1→M6 progressive controls/FE) as the centerpiece, plus Table 1 (descriptives), mechanism / heterogeneity / robustness tables, and event-study + coefficient + trend figures. Covers the full 8-step R pipeline an applied economist runs on every paper — (1) data import & cleaning (read_dta/read_csv, naniar, janitor, validate-merges), (2) variable construction (mutate/across/winsorize/group_by + lag/lead with dplyr), (3) descriptive statistics & Table 1 (gtsummary, modelsummary::datasummary, tableone), (4) classical diagnostic tests (shapiro/jarque.bera.test/bptest/dwtest/bgtest/vif/adf.test/kpss.test/Hausman), (5) baseline modeling (fixest::feols, ivreg, did::att_gt, eventstudyr, sun_ab, did_imputation, synthdid, rdrobust, MatchIt, WeightIt, grf::causal_forest, DoubleML, mediation), (6) robustness battery (modelsummary stack, clubSandwich CRSE, fwildclusterboot, ri2, robomit Oster, bacondecomp, HonestDiD), (7) further analysis (interactions + marginaleffects, mediation::mediate, gsem via lavaan, dose-response splines, grf CATE), (8) publication-ready tables & figures (modelsummary, kableExtra, gt, stargazer, texreg, flextable to LaTeX/Word/HTML; ggplot2 + ggpubr + cowplot + binsreg + iplot for figures). **Also covers two parallel domain modes that share the same 8-step scaffolding** — **Mode A — Epidemiology / public health** (target-trial emulation, IPTW + g-formula + TMLE doubly-robust triplet via `WeightIt` / `gfoRmula` / `tmle` / `ltmle`, Mendelian randomization via `MendelianRandomization` / `TwoSampleMR` / `MRPRESSO`, KM / Cox / AFT / RMST survival via `survival` / `survminer` / `flexsurv`, E-value sensitivity via `EValue`, principal stratification — STROBE / TRIPOD reporting), and **Mode B — ML causal inference** (DML via `DoubleML`, S/T/X/R/DR meta-learners via `causalweight` / `grf`, causal forest via `grf::causal_forest`, BART/BCF via `bartCause` / `bcf`, matrix completion via `MCPanel`, CATE distribution + policy tree via `policytree`, off-policy evaluation, conformal causal via `conformalInference` / `cfcausal`, fairness audit via `fairmodels`, DAG learning via `pcalg` / `bnlearn` / LLM-assisted). Use when the user asks for a complete R empirical analysis, wants a tidyverse-style reproducible R script / Quarto workflow, prefers fixest over reghdfe, needs the R counterpart to StatsPAI / 00.1 / 00.2, or names a specific R step in isolation ("feols with cluster", "MatchIt nearest neighbor", "bacondecomp in R", "gtsummary table 1", "modelsummary to Word"). Mode A triggers on "target trial emulation R", "tmle ltmle", "MendelianRandomization", "TwoSampleMR", "MRPRESSO", "survival cox AFT", "STROBE R", "EValue R", "公共健康 R", "流行病学 R". Mode B triggers on "DoubleML R", "grf causal forest", "policytree", "bartCause bcf", "conformal causal R", "fairmodels", "pcalg NOTEARS", "因果机器学习 R".
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Sample-size and statistical power calculations for planning studies. Use whenever someone asks "how many subjects/samples/replicates do I need", wants an a priori power analysis, a minimum detectable effect (MDE), a power curve, or needs to justify a sample size for a grant, IRB protocol, or pre-registration. Covers closed-form power for t-tests, ANOVA, proportions, correlations, chi-square, and regression, plus simulation-based (Monte Carlo) power for designs with no formula — logistic/Poisson regression, mixed models, cluster-randomized trials, survival, and interactions. Use this skill even when the request only mentions an effect size, alpha, or "80% power" without saying "power analysis" explicitly. For laying out the study (randomization, blocking, factorial/DOE, crossover, sequential designs) use experimental-design; for analyzing data already collected and reporting it use statistical-analysis.
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Use this skill for hands-on DOCA Arg Parser CLI work on a shipped sample or new DOCA-using app — adding / removing / renaming flags; wiring `doca_argp_init` → register params → `doca_argp_start` → `doca_argp_destroy` in order; picking a parameter type from the full public enum (`DOCA_ARGP_TYPE_STRING`, `_INT`, `_BOOLEAN`, `_DEVICE`, `_DEVICE_REP`, `_DOUBLE` — six values, not three); preserving the standard `--device` / `--representor` / `--json` (`-j`; real flag is `--json`, NOT `--json-config`) / `--sdk-log-level` surface; or debugging `DOCA_ERROR_BAD_STATE` / `INVALID_VALUE` / `NOT_SUPPORTED` / `IO_FAILED` from `doca_argp_*`. Trigger on implicit phrasings: "add a custom flag to a DOCA sample", "should I use getopt here", "BAD_STATE registering a new param", "my JSON config key is rejected", or "my sample's --json is ignored". Refuse and route elsewhere for variadic-flag / subcommand / shell-completion features, DOCA Core context, or DOCA Log internals.
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Idiomatic Golang design patterns — functional options, constructor APIs, `init()` and global-state avoidance, enums, panic vs error decisions, resource management and lifecycle, graceful shutdown, timeouts and retries, streaming and iterators, and architecture styles (clean, hexagonal, DDD, flat). Apply when choosing between architectural patterns, implementing functional options, designing constructor APIs, setting up graceful shutdown, applying resilience patterns, or asking which idiomatic Go pattern fits a specific problem. Not for wiring a DI container or comparing DI libraries (→ See `samber/cc-skills-golang@golang-dependency-injection` skill), nor for error wrapping, `errors.Is`/`As`, or logging mechanics (→ See `samber/cc-skills-golang@golang-error-handling` skill).
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Golang configuration library using spf13/viper — layered precedence (flag > env > file > KV > default), BindPFlag/BindPFlags, SetEnvPrefix + SetEnvKeyReplacer + AutomaticEnv, ReadInConfig + ConfigFileNotFoundError, Unmarshal + mapstructure struct tags, Sub for sub-trees, WatchConfig + OnConfigChange for hot reload, viper.New() for test isolation, and remote KV integration. Apply when using or adopting spf13/viper, or when the codebase imports `github.com/spf13/viper`. For CLI command structure alongside viper, see the `samber/cc-skills-golang@golang-spf13-cobra` skill. For general CLI architecture, see `samber/cc-skills-golang@golang-cli`.
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Dependency management for Golang projects — go.mod and go.sum, `go get` install and upgrade flows, Minimal Version Selection, conflict resolution with replace/exclude/retract, `govulncheck` scanning of the module tree, outdated dependency and binary size auditing, vendoring, `tool` directives, and go.work workspaces. Use when adding, removing, or upgrading Go dependencies, deciding whether to take on a package, resolving version conflicts, or auditing what a module pulls in. Covers choosing and upgrading dependency versions, not the surrounding tooling: do NOT use for fixing an exploitable vulnerability in code (→ See `samber/cc-skills-golang@golang-security` skill) or for wiring Dependabot/Renovate update bots into CI workflows (→ See `samber/cc-skills-golang@golang-continuous-integration` skill).
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Golang performance optimization patterns and methodology - if X bottleneck, then apply Y. Covers allocation reduction, CPU efficiency, memory layout, GC tuning, pooling, caching, and hot-path optimization. Use when profiling or benchmarks have identified a bottleneck and you need the right optimization pattern to fix it. Also use when performing performance code review to suggest improvements or benchmarks that could help identify quick performance gains. Not for measurement methodology (→ See `samber/cc-skills-golang@golang-benchmark` skill) or debugging workflow (→ See `samber/cc-skills-golang@golang-troubleshooting` skill).
日本語の概要は準備中です。原文の説明を表示しています。
Golang concurrency design — goroutine lifecycle and leak prevention, channels and `select`, channel ownership and direction, `sync.Mutex`/`RWMutex`/`sync.Map`/`sync.Once`/atomics, `errgroup`, `singleflight`, worker pools, and fan-out/fan-in pipelines. Use when writing or reviewing concurrent Go code, when choosing between channels and mutexes, when protecting a shared map or counter, or when a goroutine has no clear exit. Not for defensive coding unrelated to concurrency such as nil panics, slice aliasing, or numeric overflow (→ See `samber/cc-skills-golang@golang-safety` skill), and not for debugging a specific hung, crashing, or racing program after the fact (→ See `samber/cc-skills-golang@golang-troubleshooting` skill).
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Golang semantic code intelligence via `gopls`, the official Go language server — go-to-definition, find references, call/implementation hierarchy, workspace symbol search, package API discovery, diagnostics, safe rename, refactors (extract/inline/fill/rewrite code actions), formatting, and generated tests. Reaches an agent via gopls's own MCP server (`go_*` tools), Claude Code's native `LSP` tool, or the `gopls` CLI. Use when navigating or refactoring Go code — jumping to a definition, finding call sites before a rename, understanding a file's or package's dependencies, running diagnostics after an edit, or extracting/inlining/renaming. Not for the published ecosystem — packages not in your `go.mod`, versions, licenses, importers — → See `samber/cc-skills-golang@golang-pkg-go-dev` skill (`godig`). Not for a whole-tree vulnerability audit → See `samber/cc-skills-golang@golang-security` skill (`govulncheck`).
日本語の概要は準備中です。原文の説明を表示しています。
Golang CLI command tree library using spf13/cobra — cobra.Command, RunE vs Run, PersistentPreRunE hook chain, Args validators (NoArgs, ExactArgs, MatchAll, custom), persistent vs local flags, command groups, ValidArgsFunction, RegisterFlagCompletionFunc, ShellCompDirective, usage/help template customization, man-page and markdown doc generation, and testing with SetArgs/SetOut/SetErr. Apply when using or adopting spf13/cobra, or when the codebase imports `github.com/spf13/cobra`. For configuration layering alongside cobra, see the `samber/cc-skills-golang@golang-spf13-viper` skill. For general CLI architecture (project layout, exit codes, signal handling, I/O patterns), see `samber/cc-skills-golang@golang-cli`.
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Golang CLI application development. Use when building, modifying, or reviewing a Go CLI tool — especially for command structure, flag handling, configuration layering, version embedding, exit codes, I/O patterns, signal handling, shell completion, argument validation, and CLI unit testing. Also triggers when code uses cobra, viper, or urfave/cli. For cobra-specific APIs → See `samber/cc-skills-golang@golang-spf13-cobra` skill; for viper configuration layering → See `samber/cc-skills-golang@golang-spf13-viper` skill.
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GitHub Actions CI/CD pipeline configuration for Golang projects — workflow files for test, lint, SAST, coverage and vulnerability-scan jobs, Dependabot and Renovate config files, GoReleaser release pipelines, Docker build/push, repository security settings, and AI-driven PR review. Use when setting up or improving Go project CI, writing or fixing `.github/workflows/*.yml`, adding a linter or security scanner as a pipeline job, wiring automated dependency-update bots, or adding quality gates. Covers wiring tools into a pipeline, not the analysis they perform: do NOT use for choosing or interpreting security findings (→ See `samber/cc-skills-golang@golang-security` skill) or for choosing, upgrading, or auditing dependency versions (→ See `samber/cc-skills-golang@golang-dependency-management` skill).
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Production-ready Golang tests — table-driven tests, testify suites and mocks, parallel tests, fuzzing, fixtures, goroutine leak detection with goleak, snapshot testing, code coverage, integration tests, idiomatic test naming. Use when writing or reviewing Go tests, choosing a testing approach, setting up Go test CI, or debugging flaky/slow tests. For testify-specific APIs see `samber/cc-skills-golang@golang-stretchr-testify`; for measurement methodology see `samber/cc-skills-golang@golang-benchmark`.
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Golang everyday observability — the always-on signals in production. Covers structured logging with slog, Prometheus metrics, OpenTelemetry distributed tracing, continuous profiling with pprof/Pyroscope, server-side RUM event tracking, alerting, and Grafana dashboards. Apply when instrumenting Go services for production monitoring, setting up metrics or alerting, adding OpenTelemetry tracing, correlating logs with traces, migrating legacy loggers (zap/logrus/zerolog) to slog, adding observability to new features, or implementing GDPR/CCPA-compliant tracking with Customer Data Platforms (CDP). Not for temporary deep-dive performance investigation (→ See `samber/cc-skills-golang@golang-benchmark` and `samber/cc-skills-golang@golang-performance` skills).
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Detect sample contamination and cross-species reads using FastQ Screen. Screen reads against multiple reference genomes to identify bacterial, viral, adapter, or sample swap contamination. Use when suspecting cross-contamination or working with samples prone to microbial contamination.
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Alpha and beta diversity analysis for microbiome data. Calculate within-sample richness, evenness, and between-sample dissimilarity with phyloseq and vegan. Use when comparing community composition across samples or testing for group differences in microbiome structure.
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Use when generating Sankey or alluvial plots from sample annotation tables where rows are samples and selected columns are categorical stages such as risk group, response status, subtype, or cohort labels. NOT for: gene network flow analysis, continuous-value trajectories, or graph-structured pathway visualization.
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Use this skill when writing analytical SQL over time-series data with the TimescaleDB Toolkit (timescaledb_toolkit extension) hyperfunctions: approximate percentiles, statistical summaries, time-weighted averages, counter/gauge rates, uptime/heartbeat tracking, state durations, OHLC candlesticks, approximate distinct counts, top-N, and downsampling. **Trigger when user asks to:** - Compute percentiles/medians/p95/p99 over large or rolled-up time-series data - Compute rates or deltas from monotonic counters (Prometheus-style) or gauges - Compute time-weighted averages or integrals over irregularly sampled data - Track uptime/downtime from heartbeats, or time spent in each state - Build OHLC/candlestick or VWAP data for financial ticks - Store re-aggregatable summaries in continuous aggregates (two-step aggregation, rollup) - Approximate COUNT DISTINCT, find top-N / most frequent values, or downsample for charts **Keywords:** timescaledb_toolkit, hyperfunctions, percentile_agg, uddsketch, tdigest, approx_percentile, stats_agg, time_weight, counter_agg, gauge_agg, heartbeat_agg, state_agg, candlestick_agg, hyperloglog, approx_count_distinct, min_n, max_n, mcv_agg, lttb, asap_smooth, rollup, two-step aggregation
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Use when asked to compare two annual reports, put two companies from the same sector side by side, or check whether two companies' adjusted numbers mean the same thing. Takes two uploaded annual reports from one sector and compares them on five ratios computed with identical definitions from audited figures, flagging every place the companies define a metric differently. Produces a page-referenced comparison table, a definitions-differ section (adjusted vs statutory, inside vs outside the audited statements), and three questions to ask before believing either company's highlights. Educational, not financial advice.
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Given the path to a finished content-goose ad-run folder, extract everything that defines that ad — recipe shot list, VO script, characters, voices, world, atom-skills, master mp4 — and emit a `source-sample.json` in the exact shape the `upload-ad-sample` skill writes to the Goose Ads library. Also links every character and voice to the central character library at `<repo-root>/assets/character-library/` (repo-root derived from the run-dir, not a hardcoded path), and if a character isn't in the library yet, adds it first then links. Use when the user wants to remix one of their existing ads — this skill produces the source JSON that the script-rewriting step and `remix-ad` consume.
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Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
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Tests genotype-environment associations and identifies adaptive loci while correcting for the four-confound landscape (structure, demography, background selection, sampling design) using LFMM2 with mandatory K via sNMF cross-entropy elbow (LEA 3), BayPass Core/AUX/C2/IS with Omega covariance matrix, RDA / pRDA for polygenic adaptation (Forester 2018; requires imputed genotypes), OutFLANK with trimmed FST null, pcadapt, gradient forests (Ellis-Smith-Pitcher 2012, NOT mis-cited Ellis-Manel), Capblancq & Forester 2021 RDA Swiss-army-knife, genomic-offset prediction with Lind & Lotterhos 2025 three-regime caveat, Lotterhos-Whitlock sampling optima, Wang & Bradburd 2014 IBD vs IBE, and Circuitscape + ResistanceGA. Use when identifying adaptive loci across gradients, choosing K for LFMM2, deciding among GEA methods, predicting maladaptation with the novel-environment caveat, distinguishing IBD vs IBE, or optimizing sampling design.
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Runs JACKS (Joint Analysis of CRISPR/Cas9 Knockout Screens; Allen et al 2019 Genome Research) which models per-sgRNA log-fold-change as the product of a treatment-dependent gene-essentiality term and a treatment-independent guide-efficacy term. Covers the Bayesian decomposition math, the hierarchical efficacy prior shared across screens performed with the same library, when JACKS outperforms MAGeCK (multi-screen joint analysis, libraries with broad efficacy variance) and when it does not (single screen, novel libraries with no prior efficacy), library-reuse efficacy transfer, downstream essentiality interpretation, and the 2.5x sample-size reduction enabled by efficacy-aware testing. Use when running multiple screens with the same library, when guide-level noise is suspected to dominate per-gene signal, when reusing published essentiality reference screens for efficacy priors, or when comparing screens performed across cell lines that share library but differ biologically.
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