633 件 ・ 関連度順
概要と使いどころ
Guide for integrating NHGRI-EBI GWAS Catalog associations with ENCODE regulatory data. Use when users need to find GWAS variants in ENCODE peaks, connect regulatory elements to disease associations, or prioritize functional variants using ENCODE annotations. Trigger on: GWAS, genome-wide association, SNP association, trait association, GWAS Catalog, disease association, risk variant, lead SNP, LD proxy.
日本語の概要は準備中です。原文の説明を表示しています。
Run Karpathy-style autoresearch optimization on any content. Generates 50+ variants, scores with a 5-expert simulated panel, evolves winners through multiple rounds, outputs optimized version + full experiment log. Use when optimizing landing pages, email sequences, ad copy, headlines, form pages, CTA text, or any conversion-focused content. Triggers on "optimize this page", "run autoresearch", "score these variants", "A/B test this copy".
日本語の概要は準備中です。原文の説明を表示しています。
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
日本語の概要は準備中です。原文の説明を表示しています。
Splits scarce time, budget or traffic across competing products, channels, campaigns or variants by treating them as a multi-armed bandit - Thompson sampling over beta posteriors, with optimism for anything not yet tried enough to judge. Use when deciding what to work on next, how to divide a marketing budget, which product to prioritise, whether to kill something that is underperforming, or when picking a winner among test variants.
日本語の概要は準備中です。原文の説明を表示しています。
The crouton mental model for someone who has never seen this repo — what "layer" means (two different things), the two-halves rule, the three app.config registries, team-scoped multi-tenancy, manifest-driven field types, the numbered invariants with the incidents behind them, and the known-weak points. Use when orienting in this codebase for the first time, when a question is shaped like "how does crouton work / why is it built this way / where does X live", when deciding whether a change belongs in a package or a generated layer, when confused by an extends chain or by croutonApps/croutonCollections/croutonLayoutBlocks, or before proposing any structural change. Trigger phrases: "what is a crouton layer", "package vs generated layer", "how does multi-tenancy work here", "why is there a stub component", "where do field types come from", "what invariants must hold".
日本語の概要は準備中です。原文の説明を表示しています。
Heuristic-first software surgery for proof-backed, minimal-diff implementation: Contract to Invariants to Cut Rationale to inevitable incision to Proof. Use when users say "run /tw-tk", "patch-first", "keep the diff small", "state contract + invariants", "one clear incision", "fix it with a validation signal", or orchestration cues like "workers use /tw-tk" / "internally use /tw-tk".
日本語の概要は準備中です。原文の説明を表示しています。
Turn 'should never happen' into 'cannot happen' by defining owned inductive invariants and enforcing them at parse/construct/API/DB/lock/txn boundaries with a verification signal. Use when prompts mention invariants, impossible states, validation sprawl, cache/index drift, idempotency/versioning, retries/duplicates/out-of-order events, race/linearization bugs, loop correctness, or hardening another workflow (for example /tw-fix) with invariant checks first.
日本語の概要は準備中です。原文の説明を表示しています。
METAINFORMANT rules for directory docs/structural_variants. Use when editing, adding tests, or reviewing code under this path. Read the linked AGENTS.md first; use uv only, write outputs to output/, real implementations.
日本語の概要は準備中です。原文の説明を表示しています。
Produce variants of an existing Style by shifting tone (light/dark), density (compact/relaxed), or accent (palette rotation) while preserving the brand identity. Use when the user wants alternate themes derived from one brand.
日本語の概要は準備中です。原文の説明を表示しています。
Create platform-optimized social media content — captions, hashtags, headlines, calls-to-action. Covers tone-of-voice, character limits, hook writing, A/B testing variants, and content repurposing across platforms. Use when writing captions, generating hashtags, crafting hooks, creating A/B test variants, adapting content per platform, or setting up an editorial voice.
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user asks to "write the email", "draft subject lines", or "build email creative"; produces the pre-click unit — subject-line variants + preheader, body copy, one clear CTA, and a plain-text alt — message-matched to the destination page and claims-ledger-aware. Not for pre-scoring or ranking subject-line variants (spam/truncation/render pre-score) — use subject-line-lab; not for scoring the email or computing EQS — use email-quality-auditor; not for the multi-step flow — use email-sequence-designer; not for the A/B test plan — use send-experiment-designer. 邮件文案/主题行/邮件创意
日本語の概要は準備中です。原文の説明を表示しています。
Analyze session replay patterns across experiment variants to understand user behavior differences. Use when the user wants to see how users interact with different experiment variants, identify usability issues, compare behavior patterns between control and test groups, or get qualitative insights to complement quantitative experiment results.
日本語の概要は準備中です。原文の説明を表示しています。
Discover conserved quantities and symmetries from trajectory data. Identifies energy, momentum, angular momentum, and custom invariants using neural networks and symbolic methods. Inspired by Noether's theorem.
日本語の概要は準備中です。原文の説明を表示しています。
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
日本語の概要は準備中です。原文の説明を表示しています。
Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.
日本語の概要は準備中です。原文の説明を表示しています。
Design shotgun: generate multiple AI design variants, open a comparison board, collect structured feedback, and iterate. Standalone design exploration you can run anytime. Use when: "explore designs", "show me options", "design variants", "visual brainstorm", or "I don't like how this looks". Proactively suggest when the user describes a UI feature but hasn't seen what it could look like. (gstack)
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes development requirements and generates structured acceptance criteria for AEM Edge Delivery Services (EDS) tasks. Use when the user needs to define acceptance criteria, write requirements, scope work, or create a definition of done for EDS blocks, components, variants, bug fixes, or styling changes. Produces task breakdowns, identifies edge cases, and documents analysis for new blocks, variants, behavior modifications, CSS-only changes, and bug fixes.
日本語の概要は準備中です。原文の説明を表示しています。
Author the project's non-negotiable engineering rules — the constitution that every feature spec, plan, and implementation must satisfy. Load when the user asks to write a constitution, define project rules, set engineering invariants, write project standards, define non-negotiables, capture agent guardrails as policy, or when spec-driven-development orchestrator routes here. Also triggers on "project constitution", "engineering invariants", "non-negotiable rules", "project policy", "set our standards", "/constitution". Output: docs/constitution.md. The third strategic artifact alongside AGENTS.md (agent behavior) and product-soul (strategy).
日本語の概要は準備中です。原文の説明を表示しています。
Implement several variations of a design directly inside the running app, on the real page/route, with a live switcher to toggle between them in the browser, then recommend one and fold the winner into the real code. Variants are real implementations judged against real data, layout, and density (not an isolated mockup). Use this skill whenever the user wants to try design options live in the app, prototype changes directly on a real page, add a variant switcher, compare layouts in-context, asks to "build a few versions of this page", "try variants on the real screen", "switch between designs in the app", "implement this with a toggle", or says "real-prototype this". For a safe standalone .html copy that never touches the app, use the prototype skill instead.
日本語の概要は準備中です。原文の説明を表示しています。
Detects allele-specific transcription factor or histone modification binding from heterozygous-variant ChIP-seq using WASP (reference-bias filter; mandatory upstream), RASQUAL (joint QTL + bias-corrected testing), BaalChIP (Bayesian beta-binomial with copy-number-aware overdispersion), and AlleleSeq (personalized diploid genome). Handles imprinted-locus awareness, X-inactivation artifacts, cancer copy-number imbalance, and integration with downstream caQTL / bQTL mapping. Use when identifying variants with allelic effects on TF binding, fine-mapping causal regulatory variants, validating deep-learning variant predictions, or characterizing cis-acting regulatory effects.
日本語の概要は準備中です。原文の説明を表示しています。
Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.
日本語の概要は準備中です。原文の説明を表示しています。
Throwaway HTML mockups: 2-3 design variants to compare.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes development requirements and generates structured acceptance criteria for AEM Edge Delivery Services (EDS) tasks. Use when the user needs to define acceptance criteria, write requirements, scope work, or create a definition of done for EDS blocks, components, variants, bug fixes, or styling changes. Produces task breakdowns, identifies edge cases, and documents analysis for new blocks, variants, behavior modifications, CSS-only changes, and bug fixes.
日本語の概要は準備中です。原文の説明を表示しています。
OpenClawのターミナル画面を固定のサンプルデータで試作し、実際の描画部品を使った2〜6案をtmuxで並べて操作・比較するスキル。