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概要と使いどころ
SimBu can be used to simulate bulk RNA-seq datasets with known cell type fractions. You can either use your own single-cell study for the simulation or the sfaira database. Different pre-defined simulation scenarios exist, as are options to run custom simulations. Additionally, expression values can be adapted by adding an mRNA bias, which produces more biologically relevant simulations.
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Defines an S4 class for storing data from spatial -omics experiments. The class extends SingleCellExperiment to support storage and retrieval of additional information from spot-based and molecule-based platforms, including spatial coordina
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This package aims to integrate GWAS-derived SNPs and coexpression networks to mine candidate genes associated with a particular phenotype. For that, users must define a set of guide genes, which are known genes involved in the studied phenotype. Additionally, the mined candidates can be given a score that favor candidates that are hubs and/or transcription factors. The scores can then be used to rank and select the top n most promising genes for downstream experiments.
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MetaboCoreUtils defines metabolomics-related core functionality provided as low-level functions to allow a data structure-independent usage across various R packages. This includes functions to calculate between ion (adduct) and compound ma
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When we combine gene-editing technology and sequencing technology, we need to reconstruct a lineage tree from alleles generated and calculate the similarity between each pair of groups. FindIndel() and IndelForm() function will help you align each read to reference sequence and generate scar form strings respectively. IndelIdents() function will help you to define a scar form for each cell or read. IndelPlot() function will help you to visualize the distribution of deletion and insertion. TagPro
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MsCoreUtils defines low-level functions for mass spectrometry data and is independent of any high-level data structures. These functions include mass spectra processing functions (noise estimation, smoothing, binning, baseline estimation),
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PhIPData defines an S4 class for phage-immunoprecipitation sequencing (PhIP-seq) experiments. Buliding upon the RangedSummarizedExperiment class, PhIPData enables users to coordinate metadata with experimental data in analyses. Additionally, PhIPData provides specialized methods to subset and identify beads-only samples, subset objects using virus aliases, and use existing peptide libraries to populate object parameters.
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Defines a S4 class for storing data from single-cell experiments. This includes specialized methods to store and retrieve spike-in information, dimensionality reduction coordinates and size factors for each cell, along with the usual metada
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The ability to efficiently represent and manipulate genomic annotations and alignments is playing a central role when it comes to analyzing high-throughput sequencing data (a.k.a. NGS data). The GenomicRanges package defines general purpose
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Expert knowledge for Azure Role-based access control development including troubleshooting, best practices, decision making, limits & quotas, security, configuration, and integrations & coding patterns. Use when defining custom/built-in roles, ABAC conditions, deny assignments, PIM, or ARM/Bicep-based role automation, and other Azure Role-based access control related development tasks. Not for Azure Policy (use azure-policy), Azure Security (use azure-security), Azure Resource Manager (use azure-resource-manager), Azure Portal (use azure-portal).
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Expert knowledge for Azure Managed Applications development including limits & quotas, security, configuration, and deployment. Use when designing createUiDefinition UIs, JIT access, managed identities, StorageAccountSelector, or Bicep-based catalog publishing, and other Azure Managed Applications related development tasks. Not for Azure Blueprints (use azure-blueprints), Azure Resource Manager (use azure-resource-manager), Azure Lighthouse (use azure-lighthouse), Azure Partner Solutions (use azure-partner-solutions).
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Expert knowledge for Azure Deployment Environments development including troubleshooting, best practices, decision making, architecture & design patterns, limits & quotas, security, configuration, integrations & coding patterns, and deployment. Use when defining environment.yaml, configuring dev centers/projects, using ADE/Dev CLI, custom images, or CI/CD deployments, and other Azure Deployment Environments related development tasks. Not for Azure DevTest Labs (use azure-devtest-labs), Azure Dev Box (use azure-dev-box), Azure Managed Applications (use azure-managed-applications), Azure Resource Manager (use azure-resource-manager).
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Expert knowledge for Azure Connector Namespace development including configuration. Use when setting up hosted MCP servers, defining Connector Namespace endpoints, auth settings, or runtime options, and other Azure Connector Namespace related development tasks. Not for Azure Service Connector (use azure-service-connector), Azure API Management (use azure-api-management), Azure Logic Apps (use azure-logic-apps), Azure Functions (use azure-functions).
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Multichain non-custodial agent wallet via Finance District - check balances, prices, and best DeFi yields, move funds, swap, and make x402 paid API calls across EVM, Solana, Bitcoin, and Sui. Keys never leave a secure enclave (TEE); spend caps are enforced at the wallet. OAuth Connect via the dashboard MCP panel.
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Run the Definition of Done checklist for the current wp-rocket branch and report PASS/WARN/FAIL with evidence. Two modes: layer 1 (self-correction inside backend-agent / frontend-agent — resolves FAILs before handoff) and layer 2 (independent orchestrator gate — fresh perspective after handoff). Pass layer: "1" or layer: "2" when invoking.
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Framework for running single-variable cold email experiments. Defines experiment types (list-only, copy-only, combined), confidence weighting, minimum sample sizes, and success criteria. Use when the user wants to improve a campaign, test a new list vs old one, or compare copy variants. Prevents the
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The 3-bullet creative ideas email. Produces three per-company bullets that each sit in a slot the operator defined up front, so the model fills in the company detail and never invents a new idea. Triggers on "creative ideas campaign", "three ideas email", "I had a few ideas for you", "3 bullets", "use cases for their business", "what could they build with us". Outputs creative_idea_1, creative_idea_2, creative_idea_3 plus a rendered bullet block.
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Conversational intake for cold email campaigns. Interviews the user about their business, ICP (Ideal Customer Profile), offer, lead magnets, and hard vs soft filters. Outputs a structured `client-profile.yaml` that every other skill in the repo reads from. Use at the very start of a new campaign or when onboarding a new business. Triggers on "onboard me", "set up my ICP", "new client", "new business intake", "help me define my ICP".
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Use when you need to define exactly who the buyer is, what they want, what they’ve tried, and what’s driving their decisions. Trigger on "target audience", "ideal client", "who is this for", "avatar", "customer profile".
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Negotiate a pre-code contract between generator and evaluator personas that defines what "done" means before any code is written. Turns fuzzy specs into a testable target the evaluator can hold the generator to.
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Analyze how competitors present their brand — identity, messaging, positioning, voice, and visual style — to find gaps and opportunities. Use when the user says "competitor brand analysis", "analyze competitor brands", "how do competitors position themselves", "competitor messaging", "competitor identity", "what are competitors saying", "benchmark competitors", "competitive brand landscape", "how do we compare to competitors", "competitive audit", or wants to understand the brand landscape before defining their own position.
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Define KPIs, metrics, and tracking systems to measure brand health, awareness, perception, and equity over time. Use when the user says "brand measurement", "brand metrics", "how do we measure the brand", "brand KPIs", "brand health tracking", "brand awareness metrics", "brand equity measurement", "is our brand working", "brand ROI", "brand performance", "brand tracking", "brand health score", "prove brand value", "brand dashboard", or needs to show stakeholders whether brand investment is delivering results.
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Define how multiple brands, sub-brands, and product lines relate to each other under one organization. Use when the user says "brand architecture", "sub-brand", "brand portfolio", "master brand", "house of brands", "branded house", "product naming system", "how do our brands relate", "parent brand", "brand hierarchy", "brand family", "we have multiple products and need a naming system", "brand extension", "new product launch under existing brand", or when a company has grown beyond a single brand and needs a system to manage brand relationships.
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Define and sharpen a brand's market positioning — where it sits relative to competitors, what it owns, and how it differentiates. Use when the user says "brand positioning", "positioning statement", "where do we sit in the market", "how are we different", "differentiation strategy", "positioning map", "competitive positioning", "what space do we own", "brand territory", "we're too similar to competitors", "help me position this brand", or wants to find a defensible place in a crowded category.
日本語の概要は準備中です。原文の説明を表示しています。