「pact」の検索結果

Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact on regulatory elements, perform enrichment testing of variant sets in tissue-specific annotations, or link variants to target genes through enhancer-gene maps. Handles the full post-GWAS workflow from variant set → tissue mapping → functional annotation → fine-mapping awareness → enrichment → variant-to-gene → prioritization. Use this skill for ANY variant interpretation task involving ENCODE chromatin, accessibility, TF binding, or 3D genome data.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for annotating ENCODE regulatory variants with ClinVar clinical significance. Use when users need to check if variants in ENCODE peaks have clinical associations, find pathogenic variants in regulatory regions, or assess variant clinical impact. Trigger on: ClinVar, clinical significance, pathogenic variant, variant classification, clinical variant, disease variant, VUS, benign, likely pathogenic.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze features from user perspective and write user stories with acceptance criteria. Use when defining requirements, writing user stories, validating scope against project state, prioritizing features by impact, comparing approaches, analyzing user needs, or planning next work. Triggers: "user story", "acceptance criteria", "scope", "prioritize", "compare requirements", "user needs", "what to build next".

日本語の概要は準備中です。原文の説明を表示しています。

Image optimization analysis for SEO and performance. Checks alt text, file sizes, formats (WebP, AVIF), responsive images, lazy loading, CLS prevention, and Core Web Vitals image impact. Use when user says "image optimization", "alt text", "image SEO", "image size", "image audit", "WebP", "AVIF", "lazy loading", "CLS", "responsive images", or "Core Web Vitals images".

日本語の概要は準備中です。原文の説明を表示しています。

Find broken backlinks pointing to a domain using Ahrefs: links targeting 404 pages that can be reclaimed. Prioritizes highest-DR lost links for maximum recovery impact. Use when user says "broken backlinks", "broken links", "link reclamation", "dead backlinks", or "404 backlinks".

日本語の概要は準備中です。原文の説明を表示しています。

Security audit of a codebase — web apps, APIs, services, CLI tools, libraries, daemons, and more. Use when asked to find security bugs, do a security review, audit for vulnerabilities, or pen-test the code. Focuses on exploitable issues with real impact, not theoretical concerns or industry-standard behavior.

日本語の概要は準備中です。原文の説明を表示しています。

Audit a codebase against well-known software design principles: SOLID, DRY, YAGNI, KISS, Law of Demeter, Separation of Concerns, Composition over Inheritance, and the code-relevant 12-Factor subset. Scores findings by impact and effort, runs adversarial debate on contested violations, and generates a prioritized DESIGN_AUDIT.md. Use when reviewing code quality beyond what linters catch, assessing design health before a refactor, or onboarding to an unfamiliar codebase. Can be invoked standalone or delegated from tech-debt.

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Systematic technical debt analysis across architecture, testing, documentation, and infrastructure. Investigates the codebase, scores findings by impact and effort, and generates a prioritized TECH_DEBT.md remediation plan. Delegates to specialized skills for code quality (scout) and linting (lint-fix). Use when assessing overall project health, planning cleanup sprints, or onboarding to an unfamiliar codebase.

日本語の概要は準備中です。原文の説明を表示しています。

Scout Rule — identify the top 3 highest-impact improvement opportunities in files you're already touching. Analyzes entire file content, not just changed lines. Focuses on pre-existing code quality, not PR bugs. Use when preparing a PR, during code review, or after completing a feature.

日本語の概要は準備中です。原文の説明を表示しています。

Master professional email — inbox zero systems, high-impact writing, etiquette, and managing email at scale.

日本語の概要は準備中です。原文の説明を表示しています。

Coach senior leaders on strategic thinking, stakeholder management, presence, and organizational impact.

日本語の概要は準備中です。原文の説明を表示しています。

Evaluate edtech tools for their real impact on teacher time and administrative burden.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze debt payoff software — avalanche vs snowball strategy engines, interest calculation accuracy, amortization schedules, payment scheduling automation, credit score impact modeling, hardship accommodation workflows, and progress visualization.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze project dependencies for health, security, and bloat — audit outdated, deprecated, vulnerable, duplicate, heavy, and unused packages across npm, pip, cargo, go mod, and more. Produce a dependency health score, CVE inventory, license compatibility matrix, bundle size impact assessment, and a prioritized update plan with migration paths.

日本語の概要は準備中です。原文の説明を表示しています。

Four-phase skill for planning and executing large-scale codebase migrations using full-context AI analysis. Produces an impact map, ordered batch plan, subagent execution protocol, and cross-codebase validation pass. Optimized for Fable 5's 1M-token context window.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze agricultural climate risk systems for weather impact modeling, crop insurance, drought/flood prediction, soil moisture, and carbon tracking. Triggers: 'assess crop climate risk', 'evaluate weather yield models', 'review crop insurance integration'.

日本語の概要は準備中です。原文の説明を表示しています。

Audit credit risk modeling software for scoring algorithm accuracy, regulatory compliance (ECOA, FCRA, SR 11-7), bias and disparate impact testing, model governance lifecycle, and explainability..

日本語の概要は準備中です。原文の説明を表示しています。

Write a vulnerability report. Use when the user says "vulnerability report", "vuln report", "security finding", "write up this finding", "pentest finding", "bug bounty report", "security disclosure", "CVE writeup", "document this vulnerability", "how to report a security issue", or needs to formally document a security vulnerability with evidence, impact, and remediation guidance - even if they don't explicitly say "report".

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**WORKFLOW SKILL — MANDATORY for ANY hook work.** Create, configure, edit, debug, or review lifecycle hooks for VS Code Copilot (default) and Claude Code. USE FOR: criar/configurar/editar hook, hook do Copilot/Claude/agente, lifecycle hook, PreToolUse, PostToolUse, SessionStart, SubagentStop, Stop hook, UserPromptSubmit, PreCompact, bloquear comando, validar tool call, injetar contexto, guard, .agent.md frontmatter hooks, hooks.json, .github/hooks, .claude/settings.json, hook Node.js, cross-platform, hook não dispara/silencioso/ignorado, permissionDecision, hookSpecificOutput, additionalContext. **DEFAULT = VS Code GitHub Copilot.** Switch to Claude Code only when user explicitly says "Claude" OR workspace has `.claude/`. NEVER assume Claude. DO NOT USE FOR: general coding, creating agents (use agent-creator), creating skills (use skill-creator).

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when designing, generating an MVP blueprint for, auditing, troubleshooting, refactoring, or explaining an agentic harness for any domain. Covers provider-neutral agent architecture for OpenAI, Anthropic, and OpenAI-compatible APIs: agent loops, tool design, record provenance, interactive presentation, user-memory lifecycles, environment-adaptive tools, speculative tool execution, late-bound capabilities, permissions, system prompts, planning, goals, always-on agents and durable runtime, adaptive agent teams, context compaction, memory, skills, MCP/external connectors, public-board communications, hardware agents and board deployment, self-refining recursive harnesses, programmable context, continual refinement, observability, evals, prompt caching, agent-legible environments, feedback loops, and safety.

日本語の概要は準備中です。原文の説明を表示しています。

Generates sustainability-focused guidance for Google Cloud workloads based on the design principles and recommendations in the Google Cloud Well-Architected Framework (WAF). Use this skill to evaluate a workload, identify environmental impact requirements, and provide actionable recommendations to build, deploy, and manage the workload sustainably in Google Cloud.

日本語の概要は準備中です。原文の説明を表示しています。

Read-only repository explorer. Use PROACTIVELY for cold-start exploration, broad cross-file localization, or when a direct search has failed and you need to find where something lives. Skip it when the issue already names the exact file or symbol, or a previous turn already returned usable file:line evidence. Returns only compact path:line citations; its reads and greps never enter the main conversation.

日本語の概要は準備中です。原文の説明を表示しています。

Create a machine-readable phased JSON plan bundle from a spec or feature description. Produces a compact master manifest plus per-phase step files for resumable ck:cook execution.

日本語の概要は準備中です。原文の説明を表示しています。

Create a machine-readable phased JSON plan bundle from a spec or feature description. Produces a compact master manifest plus per-phase step files for resumable ck:cook execution.

日本語の概要は準備中です。原文の説明を表示しています。