「spec」の検索結果

Use when a task needs the judgment of an Application Security Engineer — checking whether an endpoint verifies object-level authorization (not just authentication), running threat modeling at design time rather than deferring security review to the end, triaging a dependency vulnerability by actual reachability rather than CVSS score alone, combining SAST/DAST/SCA tooling to cover their distinct blind spots, or applying context-specific output encoding to untrusted input. Distinct from an information security analyst — this role works inside the SDLC to prevent vulnerabilities before they ship, not detect and respond to intrusions in production.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a task needs the judgment of a licensed acupuncturist — building a TCM pattern-differentiation-based treatment plan, choosing point combinations and needling technique for a presenting complaint, triaging a safety red flag (fainting, suspected pneumothorax, herb-drug interaction), or writing a SOAP note that justifies medical necessity for insurance. US scope-of-practice default (NCCAOM/state licensure). A reasoning aid, not medical advice.

日本語の概要は準備中です。原文の説明を表示しています。

Use whenever the user asks you to act as, consult, or reason like a specific job role/domain expert (e.g. "review this like a CFO," "what would a UX designer say," "act as a contracts lawyer") and this repo's roles/ directory is available. Finds the best-matching role SKILL.md and adopts it, or honestly reports the gap if none exists.

日本語の概要は準備中です。原文の説明を表示しています。

Install bioinformatics tools for ENCODE data analysis. Covers CLI tools (BWA, STAR, samtools, MACS2), R/Bioconductor packages (DESeq2, Seurat, ChIPseeker), Python packages (Scanpy, deeptools), and Nextflow pipeline infrastructure. Generates conda environments, R install scripts, and Python requirements. Use when the user needs to set up a bioinformatics workstation, install tools for a specific assay, create reproducible environments, or troubleshoot dependency issues. Trigger on: install tools, set up environment, conda create, bioinformatics setup, install R packages, install Bioconductor, install pipeline tools.

日本語の概要は準備中です。原文の説明を表示しています。

Annotate genetic variants (GWAS hits, eQTLs, rare variants) with ENCODE functional data to interpret non-coding variation. Use when the user has variants of interest and wants to understand their regulatory context, identify causal variants from GWAS loci, assess variant impact on regulatory elements, perform enrichment testing of variant sets in tissue-specific annotations, or link variants to target genes through enhancer-gene maps. Handles the full post-GWAS workflow from variant set → tissue mapping → functional annotation → fine-mapping awareness → enrichment → variant-to-gene → prioritization. Use this skill for ANY variant interpretation task involving ENCODE chromatin, accessibility, TF binding, or 3D genome data.

日本語の概要は準備中です。原文の説明を表示しています。

Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq data across donors, labs, and platforms. Follows the Mawla et al. 2019 framework for assessing cross-study reproducibility, TIN-based quality filtering, and detection-limit-aware interpretation. Handles batch correction (Harmony/Seurat), dropout awareness, cross-contamination artifacts, and platform-specific biases. Use this skill for ANY scRNA-seq integration task, cross-dataset comparison, cell atlas construction, or reproducibility assessment involving ENCODE single-cell data.

日本語の概要は準備中です。原文の説明を表示しています。

Build comprehensive epigenomic profiles for tissues or cell types using ENCODE data. Use when the user wants to characterize chromatin states, assemble histone modification panels, create epigenomic landscapes, run ChromHMM segmentation, identify super-enhancers or bivalent domains, profile regulatory elements across a biosample, or understand epigenetic regulation in a specific biological context. Covers histone marks, chromatin accessibility, TF binding, transcription, DNA methylation, and 3D genome structure.

日本語の概要は準備中です。原文の説明を表示しています。

Search and explore ENCODE Project genomics data. Use when the user wants to find experiments, files, or explore what data is available for specific assays, organs, cell lines, or targets.

日本語の概要は準備中です。原文の説明を表示しています。

Query gnomAD (Genome Aggregation Database) for population allele frequencies, gene constraint scores, and variant annotations to interpret ENCODE regulatory variants. Use when the user needs allele frequencies for variants in ENCODE regulatory elements, wants to assess gene constraint (pLI, LOEUF) for ENCODE target genes, needs population-specific frequencies for GWAS variants overlapping cCREs, wants to filter variants by rarity before functional annotation, or is interpreting ENCODE CRISPR/MPRA results in the context of population genetics. Also use when the user mentions gnomAD, allele frequency, pLI, LOEUF, constraint, rare variants, population frequency, ExAC, or variant filtering.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for integrating GTEx tissue expression data with ENCODE regulatory elements. Use when users need to check if a gene is expressed in a tissue, correlate regulatory elements with expression, or validate ENCODE findings against GTEx. Trigger on: GTEx, tissue expression, gene expression levels, expression atlas, eQTL, tissue-specific expression, TPM values.

日本語の概要は準備中です。原文の説明を表示しています。

Access ENCODE uniform analysis pipelines, generate user-specific Nextflow/WDL pipelines, manage compute resources, and integrate with cloud platforms. Use when the user wants to understand ENCODE pipelines, run pipelines on their own data, generate custom Nextflow workflows from ENCODE pipeline code, check compute requirements (CPU/GPU/memory), run pipelines in background, or integrate with Google Cloud, AWS, or other cloud platforms. Also use when the user asks about ENCODE pipeline outputs, processing standards, software versions, or wants to replicate ENCODE processing. Covers local execution, HPC, and cloud deployment with resource-aware scheduling. Use this skill for ANY pipeline execution, workflow generation, or compute resource management task involving ENCODE data.

日本語の概要は準備中です。原文の説明を表示しています。

Build comprehensive chromatin contact maps by aggregating Hi-C loop calls (BEDPE) across multiple ENCODE experiments, donors, and labs. Use when the user wants to answer "what regions are in 3D contact in my tissue?" by creating a union catalog of chromatin loops. Handles resolution-aware anchor matching, cross-lab variation, and Hi-C-specific quality metrics.

日本語の概要は準備中です。原文の説明を表示しています。

What this skill does. Use when user mentions "keyword1", "keyword2", or "keyword3". Keep under 1,024 characters and include specific trigger keywords.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze features from user perspective and write user stories with acceptance criteria. Use when defining requirements, writing user stories, validating scope against project state, prioritizing features by impact, comparing approaches, analyzing user needs, or planning next work. Triggers: "user story", "acceptance criteria", "scope", "prioritize", "compare requirements", "user needs", "what to build next".

日本語の概要は準備中です。原文の説明を表示しています。

Coordinate structured thinking and multi-agent parallel execution for complex tasks. Use when tackling multi-step projects, planning parallel work, breaking down complex problems, coordinating specialist tasks, facing architectural decisions, or when user mentions "workflow", "orchestration", "multi-step", "coordinate", "parallel execution", "structured thinking", "break this down", "plan this out", "how should I approach", or needs help planning complex implementations.

日本語の概要は準備中です。原文の説明を表示しています。

Creates accurate frontend implementations from visual references while maintaining design consistency. Use when user provides Figma URLs, screenshots, design images, requests visual implementation from reference, or asks to build UI matching a design. Automatically checks existing design intent patterns before implementation.

日本語の概要は準備中です。原文の説明を表示しています。

Guide users through structured collaborative documentation creation. Use when user wants to write documentation, update README, create architecture docs, draft proposals, technical specs, decision docs, refactor documentation, create API docs, or document code.

日本語の概要は準備中です。原文の説明を表示しています。

Full website SEO audit with parallel subagent delegation. Crawls up to 500 pages, detects business type, delegates to up to 7 specialists, generates health score. Enhanced with live Ahrefs (DR, backlinks, traffic) and GSC (indexing, top pages) data when MCPs are available. Use when user says "audit", "full SEO check", "analyze my site", or "website health check".

日本語の概要は準備中です。原文の説明を表示しています。

Strategic SEO planning for new or existing websites. Industry-specific templates, competitive analysis, content strategy, and implementation roadmap. Use when user says "SEO plan", "SEO strategy", "content strategy", "site architecture", "SEO roadmap", "keyword strategy", "content calendar", "site architecture plan", "SEO budget", or "SEO timeline".

日本語の概要は準備中です。原文の説明を表示しています。

Generate, validate, or audit llms.txt files for AI search visibility. Crawls site structure, generates spec-compliant Markdown index for LLMs. Use when user says "llms.txt", "llm txt", "AI crawlers", "generate llms", "LLM file", "AI readability file".

日本語の概要は準備中です。原文の説明を表示しています。

Optimize content for AI Overviews (formerly SGE), ChatGPT web search, Perplexity, and other AI-powered search experiences. GEO analysis enriched with Ahrefs Brand Radar AI visibility data when available. Includes brand mention signals, AI crawler accessibility, llms.txt compliance, passage-level citability scoring, and platform-specific optimization. Use when user says "AI Overviews", "SGE", "GEO", "AI search", "LLM optimization", "Perplexity", "AI citations", "ChatGPT search", "AI visibility", or "Brand Radar".

日本語の概要は準備中です。原文の説明を表示しています。

Identify indexing problems and coverage issues using Google Search Console URL inspection data. Checks up to 20 pages for indexing status, coverage state, robots.txt state, and last crawl date. Use when user says "index issues", "indexing problems", "not indexed", "indexing coverage", or "why is my page not indexed".

日本語の概要は準備中です。原文の説明を表示しています。

Language-specific guidelines for producing high-quality Traditional Chinese (zh-TW) content: script, full-width punctuation, spacing, forms of address, grammar constraints, and Taiwan terminology. Includes the no-calque rule against literal translations of English phrasal verbs such as 折入 for fold in. Use when writing any kind of Chinese content. Including blog posts, notes, technical articles, technical writing, chitchat, social media posts, etc., even when you are just sending a text message. Also use when reviewing or editing existing Chinese content for language and terminology compliance. Always apply `writing-style-guideline` alongside this skill for structure, tone, rhetorical constraints, and banned phrases.

日本語の概要は準備中です。原文の説明を表示しています。

Create, run, and maintain API test collections using Bruno (OpenCollection YAML format and legacy Bru format). Use when the user wants to: (1) create a Bruno API test collection from scratch or from OpenAPI/Swagger specs, (2) write API request files with tests and assertions, (3) run API tests using bru CLI, (4) generate test reports (HTML, JUnit, JSON), (5) set up CI/CD pipelines (GitHub Actions) for automated API testing, (6) debug or fix failing Bruno API tests, (7) add environment configurations for API testing, (8) chain API requests with data extraction, or (9) work with any .yml/.bru Bruno collection files. Triggers on mentions of 'Bruno', 'bru CLI', 'API testing collection', 'OpenCollection', or requests to automate API testing with file-based collections.

日本語の概要は準備中です。原文の説明を表示しています。