3,140 件 ・ 関連度順
概要と使いどころ
Inverse-fold a protein backbone (PDB structure) into amino-acid sequence with ProteinMPNN (Dauparas et al. 2022, github.com/dauparas/ProteinMPNN). Reach for this skill to run sequence design on RFdiffusion backbones, to redesign one chain of a PDB while holding interface residues fixed, or to generate a temperature-swept set of sequences for downstream folding.
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Inverse-fold a backbone with ligand, nucleic-acid, and metal context using LigandMPNN (Dauparas et al. 2023, github.com/dauparas/LigandMPNN). Reach for this skill to redesign the residues lining a binding pocket around a bound small molecule or cofactor, to design metal-coordinating sites where the geometry must be respected, or to get threaded designed-sequence PDBs out of any MPNN run.
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Inverse-fold a backbone with SolubleMPNN — ProteinMPNN retrained on a soluble-PDB subset (Dauparas et al. 2022) — for sequences biased toward cytosolic expression and reduced aggregation. Reach for this skill when designs from vanilla ProteinMPNN are aggregating or going to inclusion bodies, when redesigning a membrane-adjacent fold for soluble expression, or when an E. coli expression screen is the next step.
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Structure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. 2025, github.com/jwohlwend/boltz). Reach for this skill to validate designed binders against a target, to co-fold a protein with a SMILES or CCD ligand, or to get an open-source AlphaFold3 alternative with optional binding-affinity prediction.
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Structure prediction for protein, nucleic-acid, and small-molecule complexes with the Chai-1 foundation model (Chai Discovery 2024, github.com/chaidiscovery/chai-lab). Reach for this skill to predict an antibody-antigen or protein-ligand complex from a single FASTA, to re-fold designed binders as an AlphaFold-multimer alternative, or to drive co-folding from Python for batched campaigns on a GPU.
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Biohub ESMFold2 / ESMFold2-Fast all-atom co-folding (Candido et al. 2026, github.com/Biohub/esm). Single-sequence and MSA modes; protein, DNA, RNA, ligand (CCD/SMILES), modified residues. FoldBench Ab-Ag 50-55%, PPI 70-77% DockQ-pass. Also covers the ESMC-{300M,600M,6B} protein language models from the same release: masked-LM logits, hidden states, mutation scoring, contact prediction, and the SAE interpretability head. MIT-licensed weights on HuggingFace org `biohub`. Use this skill when: (1) Predicting complex structures with single-sequence input, (2) Validating designed binders with ESMFold2-Fast, (3) Running ESMFold2 with MSA input, (4) Getting ESMC embeddings or per-residue mutation scores, (5) Choosing kernel backend and sampling-step settings for paper-faithful throughput.
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Audit and rewrite a LinkedIn profile end-to-end for 2026: headline, About 7-step, Featured, banner, photo, Experience metrics, Skills, custom URL, recommendations. Triggers on "review my profile", "rewrite my headline", "fix my About", "optimize banner", "profile audit", "LinkedIn bio". Converts resume-style profiles to ones that convert 3-5x better. Not for writing feed content (use linkedin-post-writer).
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Plan, draft, audit, and publish LinkedIn posts and comments. Use when the user wants to write a viral LinkedIn post, draft a comment or reply on any LinkedIn post URL, audit a draft against 2026 algorithm heuristics, remove AI tells, extract hook formulas from viral posts, or plan a week of content. Powered by the Publora API for publishing. User provides post/comment URLs, skill drafts content, user approves, then publishes.
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Remove AI tells from LinkedIn posts/comments: 2026 vocabulary density, reveal bridges, staccato fragments, stacked triads, performed sincerity. Tiered rewriter plus `--mode audit` LinkedIn post auditor and `--mode profile` voice builder. Not for drafting from scratch (use linkedin-post-writer) or beating AI detectors. Keywords: humanize, de-AI, post audit, post auditor, audit before posting.
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Evaluate a paper's contribution novelty, identify best-fit SSCI journal fields and ABS star rating, and recommend 20 target journals. Trigger when user says "paper submission" / "paper-submission" / "投稿评估" / "期刊推荐" / "target journal" / "选刊".
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Comprehensive Stata reference for writing correct .do files, data management, econometrics, causal inference, graphics, Mata programming, and 20 community packages (reghdfe, estout, did, rdrobust, etc.). Covers syntax, options, gotchas, and idiomatic patterns. Use this skill whenever the user asks you to write, debug, or explain Stata code.
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Deeply analyze any empirical economics PDF using the five-question framework (五问框架): research question, identification strategy, core estimand, robustness logic, and scholarly contribution. Converts the PDF to Markdown, dispatches 5 parallel sub-agents (one per question), then compiles a 2000–3000 Chinese-character report with a transferable methodology checklist. Optimized for empirical economics papers in top journals (AER, QJE, JPE, RFS, RoF, JFE, etc.). Use this skill whenever the user wants to: - systematically analyze an empirical economics paper - apply the 五问框架 (five-question framework) to a paper - extract transferable research design elements from a top-journal paper - understand a paper's identification strategy, estimand, or robustness logic - run /five-questions, /five-q, or /paper-five-q-analysis - "帮我做五问分析", "用五问框架分析这篇论文", "analyze this paper with the five-question framework"
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金融经济学实证论文计划书生成器。根据用户提供的研究方向，生成包含标题、假说、数据来源、实证策略、 预期结果表格、稳健性检验、异质性分析、机制检验等12个完整模块的研究计划书。 内置中国微观/宏观数据库（皮皮侠1599个数据集、马克数据377个数据集）和WRDS国际数据库索引， 自动匹配可用数据源。融合Edmans (2024) "Learnings From 1000 Rejections"的编辑视角作为质量护栏， 确保选题具有真正的边际贡献而非"just another determinant of Y"。 当用户提到以下任何情境时触发：写研究计划书、research proposal、论文开题、选题+计划、 帮我设计一个实证研究、empirical research design、我想研究X对Y的影响怎么做、 帮我找个能发表的选题、generate proposal、写一个可以投稿的研究方案、 研究设计、identification strategy、DID/RDD/IV研究设计。 即使用户只是描述了一个经济金融现象并想知道"能不能做成论文"，也应考虑使用此技能。
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Conduct rigorous thematic analysis (TA) of qualitative data following Braun and Clarke's (2006) six-phase framework. Use whenever the user mentions 'thematic analysis', 'TA', 'Braun and Clarke', 'qualitative coding', 'identifying themes', or asks for help analysing interviews, focus groups, open-ended survey responses, or transcripts to identify patterns. Also trigger for questions about inductive vs theoretical coding, semantic vs latent themes, essentialist vs constructionist epistemology, building a thematic map, or writing up a qualitative findings section. Covers all six phases, the four upfront analytic decisions, the 15-point quality checklist, and the five common pitfalls. Produces a Word document write-up and an annotated thematic map. Does NOT cover IPA, grounded theory, discourse analysis, conversation analysis, or narrative analysis — use a different method for those.
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公司金融实证研究的"漏斗式选题查找器"。互动开场先后询问 (1) 研究方向、(2) 候选标题数量 N， 再扫描全球文献（已出版英文学术期刊 + SSRN working paper + 全球高校 department seminar 1 年内日程），基于 Edmans (2024) "1000 Rejections" 红线生成 N 个候选标题，**通过并行 subagent（Agent 工具）批量生成计划书 + 查新；每个 subagent 必须强制调用 Skill 工具加载 econfin-proposal 与 novelty-check 两个预设 skill 完成各自模块**，**只有当 novelty score >= 9 时（即 JF/JFE/RFS 顶刊层次），subagent 才把 proposal + 查新报告合并的 md 写入 F:\Dropbox\CC\选题大全\<研究方向短名>\（以"简短选题名称-分数"命名，子文件夹名由 Step 0 从用户输入的研究方向派生）；< 9 分的选题在 subagent 内部直接丢弃，绝不写盘、绝不输出**。当用户说"找选题"、"帮我找选题"、"想做 X 方向"、 "empirical CF idea search"、"批量生成研究计划书"、"100 ideas"、"econfin-idea-finder" 时触发。
日本語の概要は準備中です。原文の説明を表示しています。
Convert English straight quotation marks ("...") to Chinese curved quotation marks ("..." U+201C/D). Use when processing Chinese text documents, markdown files, or any content that needs proper Chinese typography with directional quotes. Triggers on keywords like "转换引号", "中文引号", "英文引号转中文", "quote conversion", "convert quotes".
日本語の概要は準備中です。原文の説明を表示しています。
Convert various file formats (PDF, Office documents, images, audio, web content, structured data) to Markdown optimized for LLM processing. Use when converting documents to markdown, extracting text from PDFs/Office files, transcribing audio, performing OCR on images, extracting YouTube transcripts, or processing batches of files. Supports 20+ formats including DOCX, XLSX, PPTX, PDF, HTML, EPUB, CSV, JSON, images with OCR, and audio with transcription.
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Detect and humanize AI-generated Chinese text. 20+ rule detection categories plus statistical features (sentence-length CV, short-sentence fraction, comma density, perplexity, GLTR, DivEye) plus scene-aware LR fusion (rule × 0.2 + LR × 0.8) trained on three scenes: general / academic / longform 长文本 (≥1500 字)。Unified CLI: ./humanize {detect,rewrite,academic,style,compare}. 8 style transforms (casual/zhihu/xiaohongshu/wechat/academic/literary/weibo/novel)。 Multi-paragraph rewriting (paragraph length CV、跨段 trigram 重复) plus best-of-N humanize (默认 N=10 取最低 LR)。165 replacement patterns + CiLin 同义词词林 38873 with collision blacklist。 Academic paper AIGC reduction for CNKI/VIP/Wanfang (知网/维普/万方 AIGC 检测降重)。 Pure Python, no dependencies, offline。v5.0.0 — HC3 fused 准确率 95%、学术 hero 100→35 (-65)、 工作汇报 96→13 (-83)、长篇博客 96→41 (-55)。 Use when user says: "去AI味", "降AIGC", "人性化文本", "humanize chinese", "AI检测", "AIGC降重", "去除AI痕迹", "文本改写", "论文降重", "知网检测", "维普检测", "AI写作检测", "让文字更自然", "detect AI text", "humanize text", "reduce AIGC score", "make text human-like", "去ai化", "改成人话", "去机器味", "降低AI率", "过AIGC检测", "长文本改写", "小说改写"
日本語の概要は準備中です。原文の説明を表示しています。
中英双语学术降 AIGC / bilingual academic de-AIGC skill. Removes AI-generated writing signatures from empirical papers in economics, management, and the social sciences — in both English and Chinese. Covers Turnitin AI, GPTZero, Originality.ai on the English side and 知网 AMLC, 万方, 维普 on the Chinese side. Uses a six-step loop (intake → audit → claim-evidence check → differentiated rewrite → five-dimension self-score → cold-reader recheck) with two pattern libraries (22 English + 17 Chinese patterns), section-by-section strategies for empirical papers, and hard protections that keep every number, coefficient, and citation intact. Since 2026-08 it also carries a provenance layer (去水印): deterministic, CJK-safe cleaning of invisible-character carriers and file metadata (docx / png / jpg / svg / pdf, incl. C2PA), an honest account of Claude's statistical text watermark, and an author "ownership pass" — it never claims a text is watermark-free.
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统一采集框架 - 支持 RSS/Web/API，207+ 采集源，AI 评分/分类/摘要
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Perform comprehensive exploratory data analysis on scientific data files across 200+ file formats. This skill should be used when analyzing any scientific data file to understand its structure, content, quality, and characteristics. Automatically detects file type and generates detailed markdown reports with format-specific analysis, quality metrics, and downstream analysis recommendations. Covers chemistry, bioinformatics, microscopy, spectroscopy, proteomics, metabolomics, and general scientific data formats.
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Fast codebase search via WarpGrep (20x faster than grep)
日本語の概要は準備中です。原文の説明を表示しています。
XML sitemap audit — find and fix the sitemap problems that quietly waste crawl budget and slow indexing. Discovers the sitemap (robots.txt, /sitemap.xml, sitemap index), validates structure and size limits, and cross-checks the URLs it lists against reality: non-200 / redirected / noindex / canonicalized-away URLs that shouldn't be in a sitemap, plus indexable pages that are missing from it. Reviews lastmod accuracy, sitemap-index organization, and robots.txt reference. Use this skill whenever the user asks about sitemaps, sitemap errors in Search Console, "sitemap couldn't fetch / has errors", crawl budget, pages not getting indexed, or whether their sitemap is clean. Trigger on: "sitemap", "sitemap.xml", "XML sitemap", "sitemap errors", "sitemap audit", "couldn't fetch sitemap", "crawl budget", "pages not indexed sitemap", "sitemap index", "lastmod", "robots.txt sitemap", or any sitemap/crawl-coverage question. For a full-site SEO audit use /seo-analysis; for broken links use /broken-link-checker.
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GSC-driven content calendar. Pulls real Search Console data, finds the highest click-potential opportunities (striking-distance queries at positions 5-20, unanswered query intent, related-keyword expansions), and produces a dated, prioritized content calendar — ready to hand to /content-writer. Use when the user asks "plan my content", "what should I write next", "content calendar", "content plan", "content roadmap", "editorial calendar", "what topics will rank", "find quick-win SEO topics", "click-potential analysis", or "schedule my SEO content".
日本語の概要は準備中です。原文の説明を表示しています。