1,062 件 ・ 関連度順
概要と使いどころ
Frequency-domain analysis — FFT, power spectral density (Welch/periodogram), spectrograms, wavelet transforms, and coherence. Use for any signal with periodic, quasi-periodic, or transient frequency content in physics data.
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Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.
日本語の概要は準備中です。原文の説明を表示しています。
Monte Carlo simulation for statistical mechanics — Ising model, Metropolis-Hastings, Wolff cluster algorithm, observables (magnetization, susceptibility, specific heat), finite-size scaling, and critical phenomena analysis.
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Solve partial differential equations — finite differences, spectral methods, and physics-informed neural networks (PINNs via DeepXDE). Supports 1D/2D/3D, steady/transient, linear/nonlinear PDEs with Dirichlet, Neumann, and periodic boundary conditions.
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Generate the success criteria for a task or question, then review work against them. Given a task, goal, or open-ended question, decompose it into scenarios, evaluation perspectives, and fine-grained weighted YES/NO criteria using the Recursive Expansion Tree (RET) method; if work is supplied, score it criterion-by-criterion and surface what is missing or could be better. Use when asked to self-review or check your own work, judge whether a task is done well or completely, build a definition-of-done or completeness checklist, create an evaluation rubric or grading criteria, score or grade answers to a question, set up an LLM-as-judge rubric, or when the user mentions self-review, completeness check, success criteria, evaluation criteria, scoring rubric, Qworld, or the RET algorithm.
日本語の概要は準備中です。原文の説明を表示しています。
Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.
日本語の概要は準備中です。原文の説明を表示しています。
Build an animation from scratch, making the decisions in the order that determines whether it feels right — should it animate at all, what purpose, which tool, which properties, which curve and duration, how it interrupts, how it exits. Writes the implementation. Use when asked to animate something, add motion, make a component feel alive, or build a transition. For critiquing existing motion use review-animations; for auditing a whole codebase use improve-animations.
日本語の概要は準備中です。原文の説明を表示しています。
Plan transition from freelancer to agency with scaling. TRIGGERS - Use when user needs help with agency-builder related tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Apply HIPAA-compliant security practices for Abridge clinical AI integrations. Use when securing PHI in transit/at rest, configuring access controls, implementing audit logging, or preparing for HIPAA security audits. Trigger: "abridge security", "abridge HIPAA", "abridge PHI protection", "abridge access control", "abridge audit logging".
日本語の概要は準備中です。原文の説明を表示しています。
Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.
日本語の概要は準備中です。原文の説明を表示しています。
Segment single cells from multiplexed IMC/MIBI tissue images using Mesmer/DeepCell, Cellpose, or ilastik+CellProfiler, covering whole-cell vs nuclear segmentation, the summed-membrane-channel decision, nuclear-expansion bias, lateral spillover, resolution-floor parameters, and downstream-proxy evaluation. Use when delineating cells after preprocessing, choosing a segmentation model, building a cell mask for quantification, diagnosing impossible double-positive populations, or troubleshooting over/under-segmentation.
日本語の概要は準備中です。原文の説明を表示しています。
Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.
日本語の概要は準備中です。原文の説明を表示しています。
Produce and interpret PCA, t-SNE, UMAP, and PHATE plots for high-dimensional omics data with rigor about which method preserves what (variance, local structure, manifold, transitions), hyperparameter sensitivity, and the well-documented limits of 2D embeddings. Covers PCA biplot/scree/loadings, t-SNE PCA initialization (Kobak-Berens 2019), UMAP n_neighbors/min_dist trade-offs, and the Chari-Pachter 2023 critique. Use when visualizing high-dimensional data — bulk PCA, single-cell embeddings, multi-omics integration projections.
日本語の概要は準備中です。原文の説明を表示しています。
Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.
日本語の概要は準備中です。原文の説明を表示しています。
Quantify homologous recombination deficiency (HRD) from tumor copy number using the three genomic-scar metrics — loss of heterozygosity (LOH), large-scale state transitions (LST), and telomeric allelic imbalance (TAI) — with scarHRD, and via the whole-genome HRDetect and CHORD models. Covers the genomic instability score, the PARP-inhibitor clinical context, whole-genome-doubling correction, and the scar-versus-state distinction. Use when computing an HRD score for PARP-inhibitor eligibility, deriving LOH/LST/TAI scars from allele-specific copy number, deciding between scar-based and mutational-signature HRD methods, or interpreting an HRD result in a BRCA-reverted or low-purity tumor.
日本語の概要は準備中です。原文の説明を表示しています。
Review a feature and enhance it with purposeful animations, micro-interactions, and motion effects that improve usability and delight. Use when the user mentions adding animation, transitions, micro-interactions, motion design, hover effects, or making the UI feel more alive.
日本語の概要は準備中です。原文の説明を表示しています。
Extract a thesis's dependency fingerprint — the external variables its bull case actually rests on (key customers, suppliers/inputs, technology transitions, macro drivers, single points of failure). Use when user says "dependency map", "what does [TICKER] depend on", "dependency fingerprint", or "map exposures for [TICKER]".
日本語の概要は準備中です。原文の説明を表示しています。
Smooth color transitions and gradient-rich surfaces for modern, playful interfaces with visual depth.
日本語の概要は準備中です。原文の説明を表示しています。
Generate and safely advance the SDD Composy task projection from approved PRD, stories, and TechSpec: import contracts, list/next/show, and guarded start/block/transition/verify. Use when work must be decomposed or a task's state inspected or moved — 'quebrar a spec em tarefas', 'listar as tarefas', 'qual a próxima task', 'mark TASK-003 blocked'. Do NOT use to implement a task (sdd- execute), reconcile Markdown and JSON (sdd-sync), or for a status overview (sdd- status).
日本語の概要は準備中です。原文の説明を表示しています。
Implement exactly one SDD Composy task in the ready state with dependency preflight, TDD RED evidence, allowed paths, real verification commands, and the guarded transition to qa_required. Use when a ready task should be executed — 'executar a TASK-003', 'implementar a próxima tarefa', 'run task 4'. Do NOT use for changes without an approved task (sdd-quick), for autonomous multi-stage correction (sdd-loop), or for QA, review, or verification.
日本語の概要は準備中です。原文の説明を表示しています。
Interactive developer experience plan review. Explores developer personas, benchmarks against competitors, designs magical moments, and traces friction points before scoring. Three modes: DX EXPANSION (competitive advantage), DX POLISH (bulletproof every touchpoint), DX TRIAGE (critical gaps only). Use when asked to "DX review", "developer experience audit", "devex review", or "API design review". Proactively suggest when the user has a plan for developer-facing products (APIs, CLIs, SDKs, libraries, platforms, docs). (gstack) Voice triggers (speech-to-text aliases): "dx review", "developer experience review", "devex review", "devex audit", "API design review", "onboarding review".
日本語の概要は準備中です。原文の説明を表示しています。
Resize, crop, or export any image or video into platform-ready social media assets using Adobe Creative Cloud tools. Use this skill when a user wants to prepare a photo, image, or video for one or more social platforms — Instagram, TikTok, LinkedIn, Facebook, YouTube, Snapchat, Pinterest, Threads, or X/Twitter. Triggers on: "prepare my image for Instagram", "resize for TikTok", "get this ready to post", "make versions for all platforms", "social media sizes", "crop for stories", "export for LinkedIn", "resize my video for social", "make social media assets", or any request to adapt a photo or video for specific platforms. Handles subject-aware cropping, AI canvas expansion, test previews before full runs, and same-ratio video resizing.
日本語の概要は準備中です。原文の説明を表示しています。
Apple's approach to interface design and fluid, physical motion, translated for the web. Use when building or reviewing gesture-driven UI, spring animations, drag/swipe/sheet interactions, momentum and interruptible transitions, translucent materials and depth, typography (optical sizing, tracking, leading), reduced-motion, or the design foundations (feedback, spatial consistency, restraint) behind Apple-style interfaces.
日本語の概要は準備中です。原文の説明を表示しています。
Route user requests to the right skill, decompose complex work into parallel subagents, and manage project phase transitions. Load when the user asks "what should I do next", "which skill should I use", "orchestrate this", "run the full workflow", "split this into parallel tasks", or when a complex request spans multiple skills. Also triggers on "coordinate agents", "parallel execution", "task decomposition", "agent workflow", "what phase am I in", or when the user gives a broad instruction that requires multiple skills in sequence. This is the project's brain — it decides what runs, when, and whether to parallelise.
日本語の概要は準備中です。原文の説明を表示しています。