1.3万 件 ・ 関連度順
概要と使いどころ
Detect allele-specific chromatin accessibility from ATAC-seq using WASP, GATK ASEReadCounter, or RASQUAL. Use when mapping cis-regulatory genetic variants from heterozygous SNPs, separating cis from trans regulation, building chromatin QTL (caQTL) maps, validating GWAS variant function with allelic imbalance, or detecting reference allele mapping bias before downstream analysis.
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Implement authentication and authorization with Better Auth - a framework-agnostic TypeScript authentication framework. Features include email/password authentication with verification, OAuth providers (Google, GitHub, Discord, etc.), two-factor authentication (TOTP, SMS), passkeys/WebAuthn support, session management, role-based access control (RBAC), rate limiting, and database adapters. Use when adding authentication to applications, implementing OAuth flows, setting up 2FA/MFA, managing user sessions, configuring authorization rules, or building secure authentication systems for web applications.
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Implement proven backend architecture patterns including Clean Architecture, Hexagonal Architecture, and Domain-Driven Design. Use when architecting complex backend systems or refactoring existing applications for better maintainability.
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Process and generate multimedia content using Google Gemini API. Capabilities include analyze audio files (transcription with timestamps, summarization, speech understanding, music/sound analysis up to 9.5 hours), understand images (captioning, object detection, OCR, visual Q&A, segmentation), process videos (scene detection, Q&A, temporal analysis, YouTube URLs, up to 6 hours), extract from documents (PDF tables, forms, charts, diagrams, multi-page), generate images (text-to-image, editing, composition, refinement). Use when working with audio/video files, analyzing images or screenshots, processing PDF documents, extracting structured data from media, creating images from text prompts, or implementing multimodal AI features. Supports multiple models (Gemini 2.5/2.0) with context windows up to 2M tokens.
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Create and train AI learning plugins with AgentDB's 9 reinforcement learning algorithms. Includes Decision Transformer, Q-Learning, SARSA, Actor-Critic, and more. Use when building self-learning agents, implementing RL, or optimizing agent behavior through experience.
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Create irresistible offers and pitches using Alex Hormozi's methodology from $100M Offers. Guides through value equation, guarantee frameworks, pricing psychology, and creating offers "too good not to take" for any product or service.
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This skill should be used for time series machine learning tasks including classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search. Use when working with temporal data, sequential patterns, or time-indexed observations requiring specialized algorithms beyond standard ML approaches. Particularly suited for univariate and multivariate time series analysis with scikit-learn compatible APIs.
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Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.
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Infer gene regulatory networks (GRNs) from gene expression data using scalable algorithms (GRNBoost2, GENIE3). Use when analyzing transcriptomics data (bulk RNA-seq, single-cell RNA-seq) to identify transcription factor-target gene relationships and regulatory interactions. Supports distributed computation for large-scale datasets.
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Auto-invoked 7-phase workflow for complex-feature intent; fasttrack mode for pre-approved specs. NOT for explicit single tasks (mk:cook), green-field builds (mk:autobuild), or simple fixes (mk:fix).
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Render a wiki into ONE self-contained, offline HTML snapshot (pages + provenance) for sharing or reviewing wiki knowledge. NOT for capturing knowledge (mk:wiki) or generic diagrams (mk:preview).
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Capture, gate, and query long-term project knowledge via the gated wiki subsystem: propose candidates, recall, or search; agents propose, humans approve. NOT for short-lived memory (mk:memory).
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Read-only audit of the project's agent-tree structural overhead vs the context window. NOT for cost tracking (budget skill); NOT for read/compact decisions (mk:context-engineering).
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Fetch external sources (web/arXiv/GitHub) into scanner-gated wiki CANDIDATES, never canonical pages: guarded, capped, scanned. NOT for local knowledge (mk:wiki) or markdown fetch (mk:web-to-markdown).
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Runtime router for context decisions: read-more/stop/ask/assume/delegate, minimal read-set, compaction timing. Model: Write/Select/Compress/Isolate. NOT for agent-tree overhead audit (context-audit).
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Manages git worktrees for parallel agent isolation: creates parallel/{name}-{timestamp} branches, merges with conflict detection. NOT for user feature branches (use git worktree directly).
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Fetch a URL and return clean markdown, for arbitrary external pages (blog, RFC, GitHub issue, vendor doc) not covered by mk:docs-finder. Static-only by default; opt-in JS rendering available.
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Vulnerability analysis: OWASP Top 10, current threat landscape, supply chain security, attack surface mapping, risk prioritization. Use for security audits. NOT for STRIDE/CSO infra audits (mk:cso).
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Task claiming and file-ownership tracking for parallel execution: agents claim tasks from a shared queue with ownership enforced. Use during parallel phases with multiple simultaneous agents.
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Create a self-contained polished HTML showcase page for a topic/artifacts; mission + paths given explicitly, never auto-scans repo. Writes to assets/showcase/<mission>/. Screenshots need Puppeteer.
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Triages reviewer comments on a GitHub PR: verifies each against the codebase, then accepts/pushes back/clarifies, replies in-thread. NOT for reviewing (mk:review-pr); NOT for fixes (mk:fix).
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Structured step-by-step reasoning before acting, to avoid guessing. For complex debugging, multi-step analysis, hypothesis checks. NOT for being stuck on approach (mk:problem-solving).
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Secure skill template with prompt injection defenses. Copy this template when creating new skills.
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Generate novel UI from a text prompt via Stitch AI; exports Tailwind/HTML + DESIGN.md for mk:frontend-design handoff. NOT implementing existing designs -- use mk:figma or mk:frontend-design.
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