2,043 件 ・ 関連度順
概要と使いどころ
Call accessible chromatin regions from ATAC-seq BAM files using MACS3, MACS2, Genrich, or HMMRATAC. Use when identifying open chromatin from aligned ATAC-seq, choosing between point-source vs HMM peak callers, applying ENCODE-style pseudoreplicate IDR, removing blacklist regions, or fixing 501bp consensus peaks for downstream differential analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017 tumor tiers. Use when classifying germline variants P / LP / VUS / LB / B, applying VCEP-specific CSpec rules, computing Whiffin BS1, or assigning cancer Tier I-IV per Li 2017.
日本語の概要は準備中です。原文の説明を表示しています。
Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.
日本語の概要は準備中です。原文の説明を表示しています。
Use for all frontend and web UI tasks by default to apply a business-agnostic desktop web visual style system with medium-strength guardrails; if an existing design system is present, follow it first and use this skill only as a style harmonizer.
日本語の概要は準備中です。原文の説明を表示しています。
Guide human-centered design processes using empathy-driven methodologies. Use when the user says "lets run design thinking" or "I want to apply design thinking"
日本語の概要は準備中です。原文の説明を表示しています。
Apply systematic problem-solving methodologies to complex challenges. Use when the user says "guide me through structured problem solving" or "I want to crack this challenge with guided problem solving techniques"
日本語の概要は準備中です。原文の説明を表示しています。
Apply the bundled self-contained Godot WeChat Mini Game adapter kit to an official Godot checkout. Use when the user wants to port official Godot to WeChat Mini Game, refresh a nearby 4.6-based port, or inspect the shipped patch/source bundle for WXMEMFS, `wx.request`, audio cleanup, display/input, WXGLX dual-path rendering, `.wasm.br`, and `wx.exitMiniProgram`. This skill is version-locked to the bundled upstream base and must not be described as a generic “Godot 4.x” patch dump.
日本語の概要は準備中です。原文の説明を表示しています。
Use trace-mcp apply_codemod for any bulk mechanical change instead of repeated Edit calls. Activate whenever the same edit pattern would be applied 2+ times, across one file or many.
日本語の概要は準備中です。原文の説明を表示しています。
Use when a learner asks for help with MATLAB homework, labs, projects, graded assignments, take-home exams, quizzes, or any programming task where academic integrity, course policy, or instructor constraints may limit direct solutions. Use to provide policy-aware hints, conceptual coaching, partial feedback, and assignment-safe MATLAB tutoring.
日本語の概要は準備中です。原文の説明を表示しています。
Review and adapt MetaX attention backends, MLA, sparse indexers, cache layouts, and their kernel wrappers against a target vLLM revision and the actually installed MetaX component APIs. Verify dispatch, supported configurations, and GPU numerical behavior. Use for attention adaptations outside vllm_metax/patch/; do not apply monkey-patch headers or patch audit requirements.
日本語の概要は準備中です。原文の説明を表示しています。
Apply Rob Fitzpatrick's Mom Test discipline to customer interviews during PRD v1.0 Market Adoption. Triggers on requests to interview customers, run discovery calls, validate ideas with users, or when user asks "how do I interview customers?", "Mom Test", "Rob Fitzpatrick", "customer interview", "user research without lies", "talking to humans", "discovery conversation". Outputs CFD-* discovery entries with Mom Test-calibrated confidence.
日本語の概要は準備中です。原文の説明を表示しています。
Fix the currently-failing status checks on the current branch's PR in one sweep — route each failing check to the right diagnosis skill (via a Haiku subagent, escalating to Opus on a repeat failure), apply and verify the fix, commit, and push once — then return a summary. Use standalone when CI is red, or as the check-fixing step invoked by /watch-pr. Repo is adamayoung/TMDb.
日本語の概要は準備中です。原文の説明を表示しています。
Review the working-tree changes (vs main) for correctness, concurrency, architecture, testing, and API/doc issues — following .github/CODE_REVIEW.md — and return a severity-graded report. Scales the machinery to the diff size: a single code-reviewer agent for a small change, or a fan-out-and-verify Workflow for a large/multi-unit one. Produces findings; it does not apply fixes (the caller does).
日本語の概要は準備中です。原文の説明を表示しています。
Adversarially review the current implementation plan with three independent critic subagents, reconcile their findings into a consensus, and apply the agreed feedback to the plan. Use after drafting a plan (in plan mode or a plan/design doc) and before starting implementation, or whenever the user asks to pressure-test, critique, or harden a plan.
日本語の概要は準備中です。原文の説明を表示しています。
Редполитика проекта на русском языке: короткое интервью, извлечение голоса из примеров и файл `.agents/redpolitika.md` для редакторских скиллов. Use this skill whenever the user asks to create, update, remember, formalize, or apply a project editorial policy, tone of voice, style guide, vocabulary, forbidden words, or reusable writing context. Триггеры: «настрой редполитику», «редполитика», «запомни мой стиль», «создай гайд по стилю», «tone of voice», «ToV», «настрой скилл под наш проект», «как нам писать», «зафиксируй голос», «добавь в редполитику», «обнови правила тона», «словарь проекта», «запрещённые слова», «пиши в нашем стиле», «сохрани правила редакции». Also suggest this skill when redaktura, statya, or ux-copy lacks project context and the user will keep working with the same product. Для редактуры готового текста см. skill redaktura; для статей с нуля — statya; для интерфейса — ux-copy.
日本語の概要は準備中です。原文の説明を表示しています。
Cut AI tells from any writing. Must always apply.
日本語の概要は準備中です。原文の説明を表示しています。
Apply when reviewing or shaping code that's hard to trace. Count layers between question and answer, and hidden state in the reader's head; collapse one-caller wrappers and shrink mutable scope.
日本語の概要は準備中です。原文の説明を表示しています。
Apply before writing logic: choosing core types and data structures, sequencing scaffold-vs-feature work, asking what concurrent actors share. Get the data structures right so downstream code becomes obvious.
日本語の概要は準備中です。原文の説明を表示しています。
Apply when concurrent actors might write to the same file, branch, key, or state object. Eliminate the sharing first; serialize structurally only when one shared writer is a real invariant.
日本語の概要は準備中です。原文の説明を表示しています。
Apply when writing stateful logic, or when code branches a lot or repeats a shape assumption across files. Encode the domain in a structure instead of scattered conditionals.
日本語の概要は準備中です。原文の説明を表示しています。
Apply when introducing a new internal API while old callers still exist. Migrate callers and delete the old API in the same wave instead of preserving compatibility layers.
日本語の概要は準備中です。原文の説明を表示しています。
Apply when debugging. Trace each symptom to its root cause and fix it there; reproduce first, ask why until you reach it, resist nil-check guards that silence crashes.
日本語の概要は準備中です。原文の説明を表示しています。
Apply to any non-trivial work, not just bulk work: edits, migrations, analyses, checks. Build the tool that does it or proves it (codemod, script, generator, or a skill your subagents follow) instead of working by hand. The tool is the artifact a reviewer can rerun.
日本語の概要は準備中です。原文の説明を表示しています。
Rigorous engineering mode for nontrivial work in this repo — a set of named principles plus the leaf skills that apply them. Use when the user says "pstack", "go deep", "be rigorous", "认真做", or when a task involves architecture, a real bug, a refactor, or anything the user will not be watching. Ported from cursor/plugins pstack by Lauren Tan (MIT); see ATTRIBUTION.md.
日本語の概要は準備中です。原文の説明を表示しています。