「arc」の検索結果

Generates complete comorbidity-oriented shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction. Use when a study links two clinically related diseases through shared DEGs, enrichment, PPI hub genes, machine-learning feature selection, public diagnostic validation, gene-regulatory networks, immune infiltration, and optional downstream follow-up. Covers five study patterns (shared-DEG discovery, hub-gene prioritization, machine-learning biomarker selection, immune/regulatory interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

日本語の概要は準備中です。原文の説明を表示しています。

Generates complete process-related diagnostic biomarker bioinformatics research designs from a user-provided disease context, gene-family or pathway theme, and validation direction. Use when a study centers on process-related genes, DEG and WGCNA integration, machine-learning feature selection, nomogram-based diagnostic modeling, immune infiltration, regulatory-network analysis, and optional external or experimental validation. Covers five study patterns (process-DEG discovery, co-expression-module integration, machine-learning biomarker selection, diagnostic model/nomogram workflow, immune-regulatory interpretation and validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

日本語の概要は準備中です。原文の説明を表示しています。

Generates complete conventional single-gene oncology research designs from a user-provided cancer context, target gene, and validation direction. Use when a study centers on a fixed candidate gene and needs expression, prognosis, clinicopathologic association, functional interpretation, immune context, genomic or epigenetic context, optional drug-response hypotheses, and orthogonal validation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

日本語の概要は準備中です。原文の説明を表示しています。

Generates complete conventional non-oncology diagnostic machine-learning research designs from a user-provided disease context, optional mechanism theme, and validation direction. Use when a study centers on disease-vs-control transcriptome comparison, optional mechanism-gene restriction, feature shrinkage, diagnostic model construction, ROC / calibration / DCA evaluation, interpretation layers, and orthogonal validation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

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Matches a user’s biomedical research direction, disease problem, study aim, data modality, and resource constraints to the most relevant recent algorithms and method papers. Always search real recent algorithm literature first, prioritize the last 12 months, expand to 1–3 years only when needed, and add canonical baselines only when necessary. Every formal algorithm recommendation must include the verified primary method paper, plus published downstream papers that actually cite/use the algorithm when such papers are found, with DOI when available. Never fabricate papers, algorithm names, authors, journals, years, DOI, PMID, links, or benchmark claims. If no directly verified algorithm paper is found, say so explicitly.

日本語の概要は準備中です。原文の説明を表示しています。

Designs complete single-cell research plans from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a single-cell study — including disease-focused, mechanism-focused, biomarker-focused, translational, perturbation-inspired, or validation-aware projects. It should define the research question, choose the best-fit study pattern, recommend sample grouping logic, suggest reference datasets as examples only, specify the core analysis modules, propose a validation ladder, and output four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, sample metadata, accession numbers, cohort availability, cell-type labels, external validation resources, or literature references. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

日本語の概要は準備中です。原文の説明を表示しています。

Generates complete conventional non-oncology bioinformatics research designs from a user-provided disease context, process-related gene family or biological theme, and validation direction. Use when a study centers on multi-dataset bulk transcriptome integration, DEG analysis, process-gene intersection, enrichment analysis, GSEA, PPI hub-gene prioritization, TF/miRNA regulatory networks, ROC-based biomarker evaluation, and immune infiltration analysis. Covers five study patterns (process-DEG discovery, enrichment/GSEA interpretation, hub-gene prioritization, regulatory-network and immune interpretation, multi-layer public validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

日本語の概要は準備中です。原文の説明を表示しています。

A medical-research-native literature reading skill for users with clinical, bioinformatics, translational, and basic experimental backgrounds. Use this skill whenever a user wants to read, analyze, critique, or interpret a medical or scientific paper — whether they provide a PDF, abstract, DOI, PMID, or just a title. Triggers include requests like \"analyze this paper\", \"critique this study\", \"is this a strong paper?\", \"give me similar studies\", \"prepare me for journal club\", \"help me understand this bioinformatics paper\", \"what are the weaknesses here?\", or \"turn this into a mind map\". Also activate for any downstream deliverables such as journal club kits, comparison tables, PI decision briefs, replication starters, or follow-up experiment designs. Do NOT treat as a generic summarizer — this skill performs structured evidence-type classification, track-specific critical appraisal, interpretation-boundary judgment, and research-grade follow-up generation.

日本語の概要は準備中です。原文の説明を表示しています。

Academic paper reading and research development system for biomedical researchers. Finds papers via Semantic Scholar, reads with structured notes, tracks discussion insights, and synthesizes literature into a Research Foundation Document (RFD) for downstream protocol design skills. 8 commands: /setup /feed /read /discuss /recap /update /sync /propose

日本語の概要は準備中です。原文の説明を表示しています。

Evidence-based medical knowledge and research mentor grounded in the Bian Que tradition. Covers clinical reasoning, diagnostic thinking (望闻问切), pharmacology, pathology, differential diagnosis, medical literature appraisal, and the philosophy of early intervention. Trigger whenever users ask about medicine, clinical science, drugs, disease mechanisms, diagnosis, lab interpretation, treatment comparison, or health sciences. Even without explicit research framing, trigger on any topic touching disease, therapeutics, or clinical decision-making. Part of the AIPOCH Medical Research Skill Hub.

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A comprehensive auditor for any agent skill — including Manus, OpenClaw/ClawHub, Claude, LobeHub, or custom SKILL.md-based skills. Use this skill whenever a user wants to evaluate, audit, review, score, or quality-check an agent skill before publishing, updating, or deploying. Covers two hard veto gates (structural redlines + research integrity redlines), static quality scoring across 25 criteria (ISO 25010 + OpenSSF + Agent), dynamic test input generation, multi-mode execution testing, multi-layer output evaluation with five specialized category rubrics (Evidence Insight / Protocol Design / Data Analysis / Academic Writing / Other), a Research Veto that applies to all four research categories, human eval viewer generation, actionable P0/P1/P2 optimization recommendations, and automatic skill improvement that outputs a polished, production-ready SKILL.md. Also use whenever a user says "audit my skill", "evaluate my skill", "improve my skill", or wants a corrected version after evaluation.

日本語の概要は準備中です。原文の説明を表示しています。

Use when building a sample-level hierarchical clustering dendrogram from a bulk expression matrix and sample annotation table, especially for QC, batch inspection, or sample similarity assessment. Trigger keywords: hierarchical clustering, dendrogram, sample QC, batch inspection, sample similarity. NOT for: differential expression testing, gene clustering heatmaps, single-cell clustering workflows.

日本語の概要は準備中です。原文の説明を表示しています。

Maintain and extend the open-websearch MCP server. Trigger when changing search engines, proxy or TLS behavior, tool registration, live parsing behavior, or compatibility and regression behavior inside this repository.

日本語の概要は準備中です。原文の説明を表示しています。

This skill includes search capability in 13F, such as fuzzy search a fund information using possibly inaccurate name, or fuzzy search a stock cusip info using its name.

日本語の概要は準備中です。原文の説明を表示しています。

Autonomous research engineering — web search orchestration, source synthesis, hypothesis formation, and structured research report generation.

日本語の概要は準備中です。原文の説明を表示しています。

This skill should be used when the user asks to "find skills in the wild", "assimilate popular workflows", "discover SKILL.md files in repos", "research external skills", "find workflow patterns", "survey the skill landscape", "what skills exist out there", or wants to investigate public repositories for extractable processes, babysitter plugins, and reusable procedural insights. Searches GitHub for SKILL.md files, classifies repos by archetype, and maintains structured research under docs/reference-repos/.

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Expert cloud architect specializing in AWS/Azure/GCP multi-cloud infrastructure design, advanced IaC (Terraform/OpenTofu/CDK), FinOps cost optimization, and modern architectural patterns. Masters serverless, microservices, security, compliance, and disaster recovery. Use PROACTIVELY for cloud architecture, cost optimization, migration planning, or multi-cloud strategies.

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Expert backend architect specializing in scalable API design, microservices architecture, and distributed systems. Masters REST/GraphQL/gRPC APIs, event-driven architectures, service mesh patterns, and modern backend frameworks. Handles service boundary definition, inter-service communication, resilience patterns, and observability. Use PROACTIVELY when creating new backend services or APIs.

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Guides the creation of technical design documents before writing code, producing architecture diagrams, data models, API interface definitions, implementation plans, and multi-option trade-off analyses. Use when the user asks to plan a feature, architect a system, design an API, explore implementation approaches, or requests a technical design or spec before coding — especially for complex features involving multiple components, ambiguous requirements, or significant architectural changes.

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Research-only RPI playbook that gathers task evidence, writes dated research artifacts under .copilot-tracking/research/ or a caller's trusted evidence root, and hands off planning-ready findings. Use when the user needs evidence, alternatives, or task framing first.

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Creates reusable, source-traced research reports and coordinates provider/mode lanes with original exports. Use for 深度研究, 调研报告, literature reviews, market or company research, and ChatGPT/Kimi/UniFuncs research routes. Technology choice uses tech-selection; competitor code uses competitors-analysis.

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Build boolean and X-ray search strings to source candidates. Use when asked to build a boolean search, source candidates on LinkedIn/Google, write an X-ray search, or find people with specific skills. Produces ready-to-paste boolean strings (with synonyms, must-haves, and exclusions), X-ray variants for LinkedIn/GitHub, and a refinement plan to widen or narrow the result set.

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Designs software architecture and selects appropriate patterns for projects. Use when designing systems, choosing architecture patterns, structuring projects, making technical decisions, or when asked about microservices, monoliths, or architectural approaches.

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Fast, clean web research: search with an AI answer and cited sources. Trigger phrases: research this, web search, look up, tavily, find sources.

日本語の概要は準備中です。原文の説明を表示しています。