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Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

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Queries gnomAD v4 (807k samples), v3, v2.1.1, and constraint metrics with grpmax FAF95, bottleneck-group exclusion, LOEUF interpretation, SV/CNV/mtDNA catalogs, and Whiffin max-credible-AF framework. Use when filtering rare variants, applying ACMG BS1/BA1, ranking genes by LoF intolerance, or selecting between v2 (GRCh37 + chrX/Y constraint) and v4 (GRCh38 + 807k samples).

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Fits structural equation models to GWAS summary statistics using GenomicSEM (Grotzinger 2019), including common-factor models, confirmatory factor models, ESEM, common-factor GWAS with Q_SNP heterogeneity, multivariate Wald tests, and stratified GenomicSEM partitioned heritability. Reconciles results against MTAG multi-trait analysis. Handles sample overlap via the LDSC sampling-covariance matrix, identifies and resolves Heywood cases, and verifies model fit with CFI / RMSEA. Use when modeling latent genetic architecture across correlated traits, running multivariate GWAS on a shared factor, distinguishing factor-mediated from trait-specific SNP effects, or comparing GenomicSEM common-factor results against MTAG when both depend on accurate sampling covariance.

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Implement computer vision features including text recognition (OCR), face detection, barcode scanning, image segmentation, object tracking, and document scanning in iOS apps. Covers both the modern Swift-native Vision API (iOS 18+) and legacy VNRequest patterns, VisionKit DataScannerViewController for live camera scanning, and CoreMLRequest/VNCoreMLRequest for custom model inference. Use when adding OCR, barcode scanning, face detection, or custom Core ML model inference with Vision.

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Build private, on-device AI features on iPhone, iPad, and Mac with Foundation Models, Core ML, MLX Swift, or llama.cpp. Use when choosing an Apple-local model runtime, building an Apple Intelligence chatbot or tool-calling feature, running an LLM on Apple Silicon, converting or compressing a Python model for Core ML, or comparing on-device inference backends. For Swift Core ML loading and prediction code, use the coreml skill.

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Volcengine official documentation lookup helper. Supports both document search and full-content fetch across Volcengine products, developer tools, support content, best practices, pricing, deployment, troubleshooting, API, SDK, and policy pages.

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Use this skill any time a .pptx or .potx file is involved in any way — as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx or .potx file (even if the extracted content will be used elsewhere, like in an email or summary); editing, modifying, or updating existing presentations; combining or splitting slide files; working with templates (.potx), layouts, speaker notes, or comments. Trigger whenever the user mentions "deck," "slides," "presentation," or references a .pptx or .potx filename, regardless of what they plan to do with the content afterward. If a .pptx or .potx file needs to be opened, created, or touched, use this skill.

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Set up, repair, or migrate to Cloudflare Turnstile bot verification in an existing frontend and backend, including server-side Siteverify.

日本語の概要は準備中です。原文の説明を表示しています。

Import raw data (CSV, XLSX, TXT, or MATLAB tables) into formats used by Sensor Fusion and Tracking Toolbox. Handles both ground truth trajectories and sensor detection data. For truth: builds trackingScenarioRecording, tuning timetable, truthlog, or converted table. For sensor data: builds task-oriented dataFormat structs (preferred) or objectDetection arrays (legacy). Use when importing flight logs, GPS logs, radar detections, IR measurements, lidar/camera bounding boxes, ADS-B data, AIS ship tracks, or any recorded data for use with trackers, filter tuning, or tracker evaluation.

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Build machine vision inspection systems with MATLAB Visual Inspection Toolbox. Covers the full arc from problem selection through deployment: anomaly detection (Student-Teacher, PatchCore, FastFlow, FCDD), object detection (YOLOX), counting (CounTR, shape matching), gauging and measurement (caliper, fitcircle, fitangle), blob analysis (regionprops, calibrated measurement), shape matching for fixturing and localization, synthetic data generation for training augmentation, and deployment to standalone apps, embedded C/C++, NVIDIA GPUs (TensorRT), NPUs (ONNX), and Beckhoff PLCs. Routes to rule-based tools when problems are geometric and deterministic, AI-based tools when defect appearance varies, and hybrid pipelines combining both.

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Guides the 7-step MATLAB memory optimization workflow: baseline, profile, identify, optimize, measure, verify, report. Use when asked to reduce MATLAB memory usage, find memory bottlenecks, fix out-of-memory errors, or optimize memory-intensive code.

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Deploy AI models to embedded hardware using MathWorks tools (MATLAB, Simulink, Embedded Coder). Covers two workflow patterns: (1) MathWorks-native or imported models rebuilt as dlnetwork for lean hardware, (2) direct C/C++ code generation from PyTorch and LiteRT models. Both patterns support all targets (Cortex-M/A/R, x86, GPU). Trigger when: user wants to deploy AI to embedded targets; generate C/CUDA from neural networks; compress AI models for MCU; integrate AI in Simulink for system-level simulation; import PyTorch/ONNX/TensorFlow models for embedded deployment; optimize AI for resource-constrained hardware; or use loadPyTorchExportedProgram, loadLiteRTModel, importNetworkFromPyTorch, importNetworkFromONNX, importNetworkFromTensorFlow, importNetworkFromKeras, dlquantizer, exportNetworkToSimulink, or Embedded Coder with AI models.

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Scan package dependencies for known vulnerabilities using Snyk, Dependabot, and OWASP Dependency-Check. Identify and remediate vulnerable libraries in your software supply chain. Use when managing third-party dependencies or implementing software composition analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Optimize Linux system performance. Configure kernel parameters, analyze bottlenecks, and tune resources. Use when improving system performance.

日本語の概要は準備中です。原文の説明を表示しています。

Supply Chain Bottleneck Analyzer for Shopify/DTC stores. Diagnose cash flow, inventory, shipping costs, and customer acquisition efficiency. Includes CAC/LTV analysis, 3PL cost optimization, and ad spend benchmarks. No API key required for basic analysis.

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Supply Chain Bottleneck Analyzer for TikTok Shop sellers. Diagnose cash flow, inventory turnover, affiliate commissions, and return rates. Includes FBT cost analysis, influencer payout optimization, and viral product lifecycle management. No API key required for basic analysis.

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Supply Chain Optimization (Lite) - Diagnose bottlenecks and provide cost reduction strategies through conversation

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Supply Chain Bottleneck Analyzer for Walmart Marketplace sellers. Diagnose cash flow, inventory, WFS costs, and referral fees. Includes comparison with Amazon FBA, lower storage fee optimization, and Walmart Connect ad spend analysis. No API key required for basic analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Building applications with Large Language Models - prompt engineering, RAG patterns, and LLM integration. Use for AI-powered features, chatbots, or LLM-based automation.

日本語の概要は準備中です。原文の説明を表示しています。

Build and deploy AI agents with CloudBase Agent SDK (TypeScript & Python). Implements the AG-UI protocol for streaming agent-UI communication. Use when deploying agent servers, using LangGraph/LangChain/CrewAI adapters, building custom adapters, understanding AG-UI protocol events, or building web/mini-program UI clients. Supports both TypeScript (@cloudbase/agent-server) and Python (cloudbase-agent-server via FastAPI).

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Report concurrency and parallelism for a session — how many agents ran in parallel, concurrency-lane utilization, peak parallel width, and serialization bottlenecks (sequential chains that could have run as parallel lanes) — using the Agent Monitor workflow intelligence API. Use when checking whether a multi-agent session used parallelism efficiently.

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Send Google Chat messages via incoming webhooks — text, rich cards (cardsV2), threaded replies. TypeScript types, card builder utility, widget reference inline. Use whenever the user wants to post to Google Chat from a script, build a chatbot reply, send a notification card, build a Google Chat webhook integration, or troubleshoot card / threading issues.

日本語の概要は準備中です。原文の説明を表示しています。

Optimize LuisaCompute DSL kernels using warp/wave primitives, shared-memory aggregation, and block-level collectives. Use when kernels bottleneck on atomics, reductions, or inter-thread communication.

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Write copy following Sentry brand guidelines. Use when writing UI text, error messages, empty states, onboarding flows, 404 pages, documentation, marketing copy, or any user-facing content. Covers both Plain Speech (default) and Sentry Voice tones.

日本語の概要は準備中です。原文の説明を表示しています。