「eq」の検索結果

Babysit a GitHub pull request after creation by continuously polling review comments, CI checks/workflow runs, and mergeability state until the PR is merged/closed or user help is required. Diagnose failures, retry likely flaky failures up to 3 times, auto-fix/push branch-related issues when appropriate, and keep watching open PRs so fresh review feedback is surfaced promptly. Use when the user asks Codex to monitor a PR, watch CI, handle review comments, or keep an eye on failures and feedback on an open PR.

日本語の概要は準備中です。原文の説明を表示しています。

Use OpenClaw's exec tool to inspect orgs, sources, and run bounded read-only SQL through the OneQuery CLI directly.

日本語の概要は準備中です。原文の説明を表示しています。

Update the title and body of one or more pull requests.

日本語の概要は準備中です。原文の説明を表示しています。

Researches state-specific charitable solicitation filing requirements keyed to gross revenue, producing a citation-backed state-by-state compliance matrix of audit thresholds, financial-statement tiers, filing fees, and due dates. Use when building charity compliance matrices, researching nonprofit filing thresholds, charitable solicitation registration renewals, comparing state audit requirements for 501(c)(3) organizations, or when the user mentions audit threshold, review threshold, compilation requirement, charity filing deadline, or multi-state nonprofit compliance.

日本語の概要は準備中です。原文の説明を表示しています。

Drafts U.S. Customs and Border Protection binding ruling requests under 19 CFR Part 177 for tariff classification, valuation, origin, and marking determinations. Trigger when input mentions "binding ruling," "CBP ruling request," "19 CFR Part 177," "classification request," "HTSUS analysis," "transaction value," "country of origin," or "marking for import."

日本語の概要は準備中です。原文の説明を表示しています。

Drafts a market-standard At-The-Market (ATM) Equity Distribution Agreement for public issuers conducting continuous shelf offerings under Rule 415(a)(4). Use when establishing or renewing an ATM program under an effective Form S-3, drafting a sales agent agreement, or structuring a continuous equity offering program.

日本語の概要は準備中です。原文の説明を表示しています。

Drafts a mathematically balanced ALTA Settlement Statement for U.S. real estate closings, allocating debits and credits between buyer and seller with prorations, payoffs, lender fees, title charges, and transfer taxes. Enforces balance verification (seller credits minus debits equals cash to seller; buyer debits minus credits equals cash from buyer) and cross-references title commitment, loan documents, and purchase agreement. Use when preparing closing financials, settlement statements, HUD-equivalent documents, or real estate closing allocations.

日本語の概要は準備中です。原文の説明を表示しています。

Clarify ambiguous requirements through focused dialogue before implementation. Use when requirements are unclear, features are complex (>2 days), or involve cross-team coordination. Ask two core questions - Why? (YAGNI check) and Simpler? (KISS check) - to ensure clarity before coding.

日本語の概要は準備中です。原文の説明を表示しています。

Prepare and publish upstream issues, feature requests, discussions, pull or merge requests, and patch submissions in the channel the canonical project expects. Use when reporting a problem upstream, requesting a feature, contributing a change, or asking to submit upstream.

日本語の概要は準備中です。原文の説明を表示しています。

Checks the canonical upstream issue tracker, discussion forums, and open pull requests, merge requests, or equivalent change queues for existing reports, discussion, or work on a problem just discussed. Use before diagnosing, fixing, or reporting an apparent open-source problem to avoid duplicate effort and missed context.

日本語の概要は準備中です。原文の説明を表示しています。

Generates a pull request description for the current branch and writes it as Markdown to .git/magit/posts/new-pullreq for magit-forge. Use when the user asks for a PR description, PR summary, or write-up of what a branch changes, or is preparing to open a pull request.

日本語の概要は準備中です。原文の説明を表示しています。

Redacta un pull request para la rama actual rellenando la plantilla de PR del repositorio en función de los cambios de la rama. Úsalo cuando la persona pida abrir/crear un PR, preparar un pull request o escribir la descripción de un PR (p. ej. "abre un PR", "redacta el pull request de esta rama"). No hace merge.

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Digital equity and trauma-informed design for marginalized populations. Activate on "accessibility", "offline-first", "trauma-informed", "reentry", "recovery population", "shared device", "unstable phone", "digital equity", "design justice", "low-literacy", "intermittent access". NOT for general UX, marketing optimization, or enterprise SaaS design.

日本語の概要は準備中です。原文の説明を表示しています。

Generate publish-grade SVG+PNG technical diagrams — architecture, data flow, flowchart, sequence, agent-memory, class, ER, state-machine, comparison, timeline, and more — across 8 visual styles. Writes output to tasks/visuals/ or an active plan's visuals/ directory. Requires rsvg-convert (librsvg) for PNG export; degrades gracefully to SVG-only when absent.

日本語の概要は準備中です。原文の説明を表示しています。

Deep spec analysis on a Confluence page. Reads page (+ children) via the confluence-as wrapper, produces a structured Spec Research Report with requirements, acceptance criteria, gaps, ambiguities, and suggested user stories for human review. Read-only — does NOT create Jira tickets. Triggers: 'analyze spec for PAGE-ID', 'extract requirements from confluence page', 'spec research on URL'. NOT for raw page CRUD (mk:confluence-page); NOT for ticket complexity scoring (mk:planning-engine).

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Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 (GC-bias-aware differential via its bam_ip/bam_input control + bam_treated_ip/bam_treated_input treatment arms), QNB beta-binomial, MeTDiff HMM, and RADAR, plus the paired-symmetric edgeR/DESeq2-on-peak-counts route when batch/lot covariates need fixed-effect handling that exomePeak2's API does not accept. Covers paired vs unpaired vs interaction designs, batch confounding and per-lot meta-analysis, the stoichiometry-vs-expression-vs-IP-efficiency confound, and effect-size filtering against under-powered N=2 designs. Use when comparing m6A across two or more conditions, choosing between exomePeak2/QNB/RADAR/MeTDiff for a design, handling batch confounding when exomePeak2's API is too rigid, distinguishing real hyper/hypo-methylation from expression shifts, applying effect-size thresholds, or planning orthogonal stoichiometry validation (GLORI/SAC-seq/m6Anet mod_ratio).

日本語の概要は準備中です。原文の説明を表示しています。

Build volcano and MA plots from differential-expression / association results with LFC shrinkage, FDR-adjusted thresholds, sensible label placement, and axis-truncation conventions. Covers EnhancedVolcano, ggplot2, matplotlib, and the apeglm/ashr/normal shrinkage decision. Use when visualizing differential-expression results (RNA-seq, ChIP-seq, ATAC-seq, proteomics) or any per-feature effect-size + p-value table.

日本語の概要は準備中です。原文の説明を表示しています。

Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural splines, maSigPro (Nueda 2014 for RNA-seq), ImpulseDE2 with explicit impulse-model failure modes, DREAM for repeated measures via linear mixed models, pseudoreplication avoidance, conditional vs marginal modeling, and trajectory clustering with DPGP, Mfuzz (with Schwämmle 2010 fuzzifier estimation), and splines+k-means. Use when modeling time-course or longitudinal expression, choosing factor vs spline, handling repeated measures from the same subject, avoiding pseudoreplication, clustering temporal trajectories, or selecting between dedicated time-course tools and pairwise+LRT.

日本語の概要は準備中です。原文の説明を表示しています。

Build genome-browser-style multi-track figures with pyGenomeTracks (config-driven), Gviz (R), and IGV batch screenshotting. Covers BigWig coverage tracks, BED/peak overlays, gene-model rendering, Hi-C matrix tracks, BedPE link arcs, spike-in-aware normalization, and the bamCoverage --normalizeUsing trap. Use when producing publication figures of genomic loci with stacked aligned tracks (coverage, peaks, genes, interactions) for ChIP-seq, ATAC-seq, RNA-seq, Hi-C, or generic locus visualization.

日本語の概要は準備中です。原文の説明を表示しています。

Generate consensus FASTA sequences by applying VCF variants onto a reference with bcftools consensus, or build viral/amplicon consensus with iVar. Use when reconstructing a sample-specific reference or haplotype, deciding -H haplotype vs IUPAC vs all-ALT projection, masking no-coverage sites so a consensus does not manufacture false reference calls, or setting iVar min-depth/min-frequency policy for surveillance genomes.

日本語の概要は準備中です。原文の説明を表示しています。

Read, write, and index compressed sequence files (gzip, bzip2, xz, BGZF) with Biopython and bgzip/samtools. Use when working with .gz, .bz2, or .bgz sequence files, when random access into a compressed FASTA/FASTQ is needed, or when SeqIO.index/faidx/tabix rejects a plain .gz. Covers the BGZF-vs-gzip seekability asymmetry, the 'rt'-not-'rb' handle trap, virtual offsets, and gzip-to-BGZF conversion.

日本語の概要は準備中です。原文の説明を表示しています。

Map N6-methyladenosine (m6A) RNA modifications at single-nucleotide resolution using miCLIP (Linder 2015), miCLIP2 + m6Aboost machine learning (Kortel 2021), GLORI (Liu 2023, antibody-free chemical conversion), DART-seq (Meyer 2019, APOBEC1-YTH fusion), m6Anet (nanopore direct RNA), or MeRIP-seq with calibration. Use when distinguishing antibody-based from antibody-free m6A detection methods, applying the DRACH motif constraint, reconciling cross-method disagreements (DART 44% in DRACH vs GLORI), or detecting m6Am at the cap.

日本語の概要は準備中です。原文の説明を表示しています。

Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

日本語の概要は準備中です。原文の説明を表示しています。