「cer」の検索結果

Use when adding cross-cutting concerns to durable functions — structured logging or tracing across all functions, error tracking with Sentry, payload encryption for sensitive data, dependency injection of clients (DB, Stripe, etc.) into function handlers, custom telemetry, or behavior that should apply uniformly across many functions. Covers Inngest middleware lifecycle, creating custom middleware, dependencyInjectionMiddleware, @inngest/middleware-encryption, @inngest/middleware-sentry, and custom middleware patterns.

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Extract GWP, life-cycle stages, certifications, and impact metrics from an EPD PDF. Use when given a declaration to parse; not to find or compare EPDs.

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Audit a product, selection or FF&E schedule against sourced evidence and flag discrepancies, unknowns and stale specifications. Use to check product data; not to repair records, certify compliance or generate cut sheets.

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Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations, FDA/EMA drug labels, and PGx pathways. Two-host architecture: api.clinpgx.org for annotation records, api.cpicpgx.org for genotype→recommendation lookups. No auth. For germline pathogenicity use clinvar-database; for somatic cancer PGx use cosmic-database or opentargets-database; for drug bioactivity use chembl-database-bioactivity.

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Query ReMap 2022 TF ChIP-seq peak database via REST API and BED downloads. Retrieve TF peaks overlapping a region (chr:start-end), peaks near a gene, TFs by species, peaks filtered by biotype (promoter, enhancer), and BED files for a TF-cell type pair. Use for TF co-occupancy, regulatory annotation, and TF binding atlases. Use jaspar-database for PWM motifs; encode-database for ENCODE tracks.

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Query COSMIC for cancer somatic mutations, gene census, mutational signatures, drug resistance variants. REST API v3.1 supports gene/sample/variant queries; free registration. For germline use clinvar-database; for drug-target data use opentargets-database or chembl-database-bioactivity.

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Deep generative models for single-cell omics: probabilistic batch correction (scVI), semi-supervised annotation (scANVI), CITE-seq RNA+protein (totalVI), transfer learning (scARCHES), and DE with uncertainty. Unified setup→train→extract API on AnnData. Use harmony-batch-correction for fast linear correction without deep learning; muon for multi-modal MuData workflows.

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Unified CLI/Python interface to 20+ genomic databases. Gene lookups (Ensembl search/info/seq), BLAST/BLAT, AlphaFold, Enrichr enrichment, OpenTargets disease/drug, CELLxGENE single-cell, cBioPortal/COSMIC cancer, ARCHS4 expression. Spans genomics, proteomics, disease. For batch/advanced BLAST use biopython; for multi-DB Python SDK use bioservices.

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Automated scRNA-seq cell type annotation via pre-trained logistic regression. 45+ models: immune, gut, lung, brain, fetal, cancer microenvironments. Input normalized AnnData; outputs per-cell labels, majority-vote cluster labels, confidence scores. Use for fast, reference-backed annotation without manual marker inspection.

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Consensus cell type annotation: runs 10+ algorithms (KNN-Harmony/BBKNN/Scanorama/scVI, CellTypist, ONCLASS, Random Forest, SCANVI, SVM, XGBoost) on a labeled reference and transfers labels via majority voting. Outputs per-method labels, consensus, agreement score. Use when single-method annotation is insufficient or you need ensemble uncertainty for novel states.

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Cancer genomics (TCGA et al.) via cBioPortal REST API. Retrieve somatic mutations, CNAs, expression, clinical data (survival/stage/treatment) across thousands of studies. Use for TMB, oncoprints, survival analysis. For population frequencies use gnomad-database; for drug-gene interactions use opentargets-database.

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Infer and visualize intercellular communication from scRNA-seq with CellChat (R). Build CellChat from Seurat/counts → subset CellChatDB ligand-receptor pairs → over-expressed genes per group → communication probabilities → pathway signaling → network centrality (senders/receivers/influencers) → chord/heatmap/bubble plots → cross-condition compare. Human, mouse. Use liana for pure-Python.

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Query and download NCI Imaging Data Commons (IDC) cancer radiology and pathology datasets via the idc-index Python client. No authentication required: the parquet index ships inside the pip wheel, SQL runs locally via DuckDB, and DICOM downloads stream from public S3/GCS buckets through s5cmd. Use sql_query() for DuckDB cohort selection, get_collections/get_patients/get_dicom_studies/get_dicom_series for hierarchical browsing, download_from_selection() for downloads, and get_viewer_URL() for OHIF/Slim links. Use pydicom-medical-imaging for local DICOM reading; histolab for whole-slide pathology preprocessing.

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MCP server optimization and transport layer enhancement for claude-flow v3. Implements connection pooling, load balancing, tool registry optimization, and performance monitoring for sub-100ms response times.

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Comprehensive GitHub project management with swarm-coordinated issue tracking, project board automation, and sprint planning

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Complete security architecture overhaul for claude-flow v3. Addresses critical CVEs (CVE-1, CVE-2, CVE-3) and implements secure-by-default patterns. Use for security-first v3 implementation.

日本語の概要は準備中です。原文の説明を表示しています。

Comprehensive GitHub release orchestration with AI swarm coordination for automated versioning, testing, deployment, and rollback management

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Implement semantic vector search with AgentDB for intelligent document retrieval, similarity matching, and context-aware querying. Use when building RAG systems, semantic search engines, or intelligent knowledge bases.

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Optimize AgentDB performance with quantization (4-32x memory reduction), HNSW indexing (150x faster search), caching, and batch operations. Use when optimizing memory usage, improving search speed, or scaling to millions of vectors.

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Unify 6+ memory systems into AgentDB with HNSW indexing for 150x-12,500x search improvements. Implements ADR-006 (Unified Memory Service) and ADR-009 (Hybrid Memory Backend).

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Automated coordination, formatting, and learning from Claude Code operations using intelligent hooks with MCP integration. Includes pre/post task hooks, session management, Git integration, memory coordination, and neural pattern training for enhanced development workflows.

日本語の概要は準備中です。原文の説明を表示しています。

Multi-repository coordination, synchronization, and architecture management with AI swarm orchestration

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Implement persistent memory patterns for AI agents using AgentDB. Includes session memory, long-term storage, pattern learning, and context management. Use when building stateful agents, chat systems, or intelligent assistants.

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Drive a PR to an approved code review by looping OCR's multi-agent review and address steps. Runs /ocr:review then /ocr:address repeatedly until the review verdict is APPROVE, then one final /ocr:address for leftover suggestions, posting every review and every address round to the GitHub PR as comments. Use when the user asks to 'review and address in a loop', 'iterate review until approved', 'auto review-and-fix this PR', 'loop /ocr:review and /ocr:address', or to take a changeset all the way to a clean APPROVE with the default reviewer team. Wraps the /ocr:review (.ocr/commands/review.md) and /ocr:address (.ocr/commands/address.md) skills; needs a feature branch with an open GitHub PR and the gh CLI for posting.

日本語の概要は準備中です。原文の説明を表示しています。