「ida」の検索結果

Design evidence-discovery and validation workflows for drug repurposing studies by integrating disease mechanisms, drug-target logic, expression reversal, real-world evidence, and validation routes into a closed-loop study blueprint.

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Generates complete single-compound network-toxicology research designs from one exposure, one disease or toxic phenotype, and a validation direction. Use when a study centers on one compound–one disease link and needs target collection, overlap construction, enrichment, PPI hub prioritization, docking, optional transcriptomic cross-check, and conservative mechanistic synthesis. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

日本語の概要は準備中です。原文の説明を表示しています。

Designs complete research plans that integrate clinical variables with multi-omics data from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a study that combines clinical variables with transcriptomics, proteomics, metabolomics, epigenomics, or related omics layers for mechanism interpretation, biomarker development, risk stratification, treatment-response analysis, or translational use. It should define the clinical use case, alignment across data layers, feature-reduction and fusion logic, modeling route, mechanism-interpretation layer, validation ladder, and four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, platform coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

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Detects overlooked, underrepresented, weakly resolved, or poorly validated populations and subgroups within a biomedical research area so users can identify more precise and meaningful study populations. Always use this skill when the real question is not just what is under-studied, but which populations, strata, or subgroups are missing, thinly represented, superficially analyzed, pooled without resolution, or insufficiently validated in the current evidence base. Focus on meaningful subgroup gaps rather than generic calls for diversity.

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Detects methodological gaps across study design, analysis, validation, bias control, reproducibility, and implementation readiness within a biomedical research area. Use this skill when a user wants to identify what current studies are still methodologically missing, which weaknesses are most consequential, and what upgrade path would produce a stronger next-step study. Always separate design gaps, analysis gaps, validation gaps, and reproducibility gaps. Never treat technical complexity as methodological rigor.

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Reverse-engineers the methods section of a biomedical paper into a structured, reproducible workflow. Use this skill when a user wants to understand how a study was actually executed, extract data sources, inclusion/exclusion logic, preprocessing, analytical sequence, software/tools, validation path, and critical parameters, or build a replication checklist from a paper, abstract, DOI, PMID, title, screenshot, or partial methods text. Do not treat this as generic summarization. Focus on reconstructing the operational method pipeline, surfacing missing reproducibility details, and distinguishing explicitly reported steps from inferred or unresolved ones. Never fabricate references, methods details, identifiers, software versions, parameters, datasets, or validation steps.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies translationally meaningful paths for bioinformatics findings by mapping omics or computational discoveries to diagnosis, stratification, prognosis, treatment-response, monitoring, or target-nomination use cases, while auditing bridge evidence, assayability, and validation burden. Use this skill when a user wants to know whether a bioinformatics finding can be framed as a stronger translational topic without overclaiming clinical relevance. Always separate statistical signal from translational value, and never imply clinical utility, targetability, or validation depth without explicit evidence support.

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Scans the biomarker landscape of a disease area by biomarker type, clinical/research use case, evidence layer, validation status, and maturity level. Use this skill when a user wants a field-level biomarker evidence map rather than a generic literature summary. Always separate exploratory biomarkers from externally validated or clinically embedded biomarkers, and never imply clinical maturity without explicit evidence support.

日本語の概要は準備中です。原文の説明を表示しています。

Use when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk distribution plots, heatmap, and time-dependent ROC curves. NOT for: model training, feature selection, nomogram construction, calibration analysis, or single-cell data.

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Validate and repair proposed resource allocations by replaying them against temporary capacity. Use when actions consume several resource dimensions such as CPU, memory, GPUs, or accelerators.

日本語の概要は準備中です。原文の説明を表示しています。

Generate Zod/JSON Schema configuration validators with defaults and error messages.

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Guardrails AI validation framework setup for LLM applications. Implement input/output validation, safety checks, and structured output enforcement.

日本語の概要は準備中です。原文の説明を表示しています。

Validates Conductor project artifacts for completeness, consistency, and correctness. Use after setup, when diagnosing issues, or before implementation to verify project context.

日本語の概要は準備中です。原文の説明を表示しています。

Implement data quality validation with Great Expectations, dbt tests, and data contracts. Use when building data quality pipelines, implementing validation rules, or establishing data contracts.

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Für Liquidated Damages: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt.

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Japanese (and other non-Hollywood) screenwriting methods (日本编剧方法/原创剧本实战) — distilled from ten Japanese directors and writers in ゼロからの脚本術; Kosawa Ryota (three acts as 起承转合, speed by jumping), Uchida Kenji (beautiful structure, time-axis tricks), Miki Satoshi (small-material notebook, theme emerges later), Sono Sion, Omiya Ellie (dialogue from inner monologue), Kakei Masaya ("if + moreover"), Fukuda Yuichi (character = actor + flaw, audience as tsukkomi), Yokohama Satoko, Takahashi Izumi ("pain"), Yukisada Isao (situation-born originals); plus Arai Haruhiko (IP adaptation, "write what you're ashamed of"). Neighbours; sw-korean-french-screenwriting, ozu-screenplay-style. Use when writing an original Japanese-style script or TV drama, working from small material and fragments, choosing between structure-first and character-first methods, building a Japanese 企画書, designing comedy tsukkomi systems, or when Hollywood models feel wrong for a quiet, daily-life, non-goal-driven story.

Validate bibliography entries against citations in all lecture files. Structural checks (missing/unused entries, malformed fields) by default; `--semantic` adds citation-drift detection, DOI verification, and style-consistency checks.

日本語の概要は準備中です。原文の説明を表示しています。

AI DevKit · Testing phase guidance for adding and validating feature test coverage. Use when the user wants to write tests, update testing docs, run coverage, close coverage gaps, or run dev-lifecycle phase 8.

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AI DevKit · Design phase guidance for reviewing feature design against requirements. Use when the user wants to validate architecture, review design docs, resolve design trade-offs, or run dev-lifecycle phase 3.

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Guidance for instrumenting webapps with Azure Application Insights. Provides telemetry patterns, SDK setup, and configuration references. WHEN: how to instrument app, App Insights SDK, telemetry patterns, what is App Insights, Application Insights guidance, instrumentation examples, APM best practices.

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Check/manage Azure quotas and usage across providers. For deployment planning, capacity validation, region selection. WHEN: "check quotas", "service limits", "current usage", "request quota increase", "quota exceeded", "validate capacity", "regional availability", "provisioning limits", "vCPU limit", "how many vCPUs available in my subscription".

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Execute Azure deployments for ALREADY-PREPARED applications that have existing .azure/deployment-plan.md and infrastructure files. DO NOT use this skill when the user asks to CREATE a new application — use azure-prepare instead. This skill runs azd up, azd deploy, terraform apply, and az deployment commands with built-in error recovery. Requires .azure/deployment-plan.md from azure-prepare and validated status from azure-validate. WHEN: "run azd up", "run azd deploy", "execute deployment", "push to production", "push to cloud", "go live", "ship it", "bicep deploy", "terraform apply", "publish to Azure", "launch on Azure". DO NOT USE WHEN: "create and deploy", "build and deploy", "create a new app", "set up infrastructure", "create and deploy to Azure using Terraform" — use azure-prepare for these.

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Maintenance orchestrator for the brooks-lint plugin itself. Runs a sequential subagent pipeline — author → eval → QA → trigger-audit → release — to add or edit a skill, refresh the eval suite, keep the four manifests + all README translations + CHANGELOG + AGENTS/GEMINI in sync, audit trigger boundaries, and cut releases. Drives the five agents in .codex/agents/ (skill-author, eval-curator, consistency-qa, trigger-boundary-auditor, release-manager). Triggers when the maintainer asks to work ON brooks-lint itself: "add a new skill", "edit the brooks-debt guide", "update the eval suite", "fix the trigger descriptions", "make this change and validate it", "release brooks-lint", "bump and publish", and follow-ups: "re-run", "re-validate", "update that skill", "redo the audit", "do the X part again". Do NOT trigger for: USING the brooks-lint analysis skills on some target codebase (that's brooks-review / brooks-audit / brooks-debt / brooks-test / brooks-health / brooks-sweep); generic questions about brooks-lint that don't ask to change it; or maintenance of a different plugin.

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Create and validate HVE Core agents, prompts, instructions, and skills with current frontmatter, package membership, delegation, tracking, documentation, and validation conventions. Use when authoring a GitHub Copilot customization artifact in this repository.

日本語の概要は準備中です。原文の説明を表示しています。