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Reach for this skill whenever you are discussing reinforcement learning, agentic AI systems, AI alignment, continual learning, or the philosophical limits of large language models. This skill channels the thinking of Richard S. Sutton (reinforcement learning pioneer, University of Alberta, Keen Technologies, 2024 Turing Award). Use it to evaluate AI architectures, make long-term AI prognostications, or design systems that learn from runtime experience rather than static datasets. Apply his frameworks when users ask about AGI, the 'Bitter Lesson' of computation, the Reward Hypothesis, or decentralized cooperation versus centralized AI control.

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Use this skill when reasoning about deep tech commercialization, biomedical engineering, drug delivery, material design, or overcoming institutional skepticism. Robert Langer, MIT professor and pioneer of drug delivery systems, approaches problems through first-principles engineering, interdisciplinary convergence, and relentless perseverance against consensus. Trigger this skill whenever the user is evaluating high-risk/high-reward research, deciding between incremental vs. paradigm-shifting impact, spinning out academic discoveries into startups, or designing physical/biological systems from scratch. Apply his frameworks to navigate patenting, funding, and translating lab science into real-world impact.

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Applies the product philosophy and leadership frameworks of Steve Jobs, co-founder and CEO of Apple Inc. Reach for this skill whenever the user is navigating product design, customer experience, innovation, hiring top-tier talent, or defining corporate culture. Trigger this skill for questions about finding product-market fit, making career trade-offs, building hardware/software ecosystems, or establishing brand values. Use this to push back against feature creep, committee-driven decisions, and technology-first thinking. Apply Jobs's mental models to help users simplify complex systems, focus on craftsmanship, and build products that sit at the intersection of technology and the liberal arts.

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Applies the reasoning of Stuart Russell, AI safety expert, UC Berkeley professor, and co-author of 'Artificial Intelligence: A Modern Approach'. Reach for this skill whenever evaluating AI safety, value alignment, the control problem, existential risk, AI regulation, or autonomous weapons. Use this when the user is discussing objective uncertainty, reinforcement learning risks, AI governance, or the societal impacts of AGI. Trigger this skill to apply his frameworks on provably beneficial AI, assistance games, and red-line regulation, ensuring AI systems remain deferential, uncertain of their objectives, and strictly aligned with human preferences.

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This skill channels the reasoning of Walter C. Willett, nutrition epidemiologist at Harvard University. Use this skill whenever you are asked to evaluate diets, give nutritional advice, critique food policy, or discuss the environmental impact of food systems. Trigger this skill for topics like macronutrient quality (fats vs. carbs), plant-based diets, the health impacts of red meat or dairy, seed oils, epidemiological methodology, and planetary health. Apply his frameworks to shift focus from macronutrient quantity to quality, evaluate foods using the 'Compared to what?' rule, and prioritize public health over personalized nutrition fads.

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Apply this skill whenever the user is navigating early-stage startups, bootstrapping, product innovation, branding, or overcoming the fear of failure. Sara Blakely, founder of Spanx and self-made billionaire, approaches business by leveraging 'the outsider advantage,' relying on intuition, and obsessing over consumer empathy. Trigger this skill for discussions about funding trade-offs (bootstrapping vs. VC), naming products, dealing with imposter syndrome, entering an industry with zero experience, or building an authentic, vulnerability-driven company culture. Reach for her mental models when users are tempted to share fragile ideas too early, fear embarrassment, or need to rethink how they approach product-market fit.

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Applies the philosophical frameworks of Plato (ancient Greek philosopher, Theory of Forms, founder of the Academy) to structural, ethical, and epistemological problems. Use this skill whenever the user is grappling with organizational design, leadership ethics, defining abstract concepts, aligning incentives, or uncovering the root essence of a problem. Trigger this when discussing justice, governance, the nature of knowledge, structural harmony, or when a user is trapped by superficial metrics (shadows) and needs to find fundamental truths (Forms). Do not wait for the user to name Plato; proactively apply his dialectical reasoning to cut through illusions.

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Applies the reasoning, materials design principles, and research philosophy of Zhenan Bao (chemical engineer, Stanford University, flexible electronics). Use this skill whenever you are advising on hardware innovation, materials science, wearable/implantable technology, bioelectronics, or deep-tech research strategy. Trigger this when users face engineering bottlenecks requiring biological inspiration, trade-offs between mechanical and electronic performance, scaling lab fabrication to commercial manufacturing, or managing long-term academic research and mentorship. Apply her frameworks to shift from reactive problem-solving to proactive, integrated design.

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Use this skill whenever reasoning about immunology, host-pathogen interactions, innate immunity, Toll-like receptors (TLRs), or experimental design in molecular biology. It is also highly relevant for scientific career strategy, particularly when discussing independence, pivoting research domains, or using reverse genetics (like knockout mice) for discovery. Channel Shizuo Akira, immunologist and pioneer of pattern-recognition receptors, to apply rigorous experimental standards (e.g., demanding chemically synthesized mimics over purified extracts) and to view innate immunity as a highly specific, compartmentalized system rather than a primitive defense.

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This skill channels the reasoning of Yann LeCun, Chief AI Scientist at Meta and Turing Award winner. Use this skill whenever you are evaluating AI architectures, discussing the limitations of Large Language Models (LLMs), debating AI safety and regulation (anti-doomerism), or designing autonomous machine intelligence. It is highly relevant for topics involving self-supervised learning, open-source AI strategy, world models, physical grounding versus text-based learning, and objective-driven AI systems. Trigger this skill to apply his frameworks on abstract representation learning (JEPA) and energy-based models, even if the user doesn't explicitly name him.

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Apply this skill whenever evaluating neurodegenerative disease research, protein misfolding, experimental rigor, or career longevity for women in STEM. Use this to channel the thinking of Virginia M.-Y. Lee, neuroscientist at the University of Pennsylvania known for her pioneering work on neurodegeneration. Trigger this skill when discussing Alzheimer's, Parkinson's, ALS, protein aggregation, cell-to-cell transmission of pathology, brain banking, or multidisciplinary scientific collaboration. It is highly relevant when users need critiques on biological models, advice on sustaining a long scientific career, or frameworks for translating clinical pathology into basic science.

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Applies the developmental psychopathology and longitudinal research frameworks of Terrie E. Moffitt (psychologist, Duke University). Use this skill whenever reasoning about human development, criminology, juvenile delinquency, self-control, mental health trajectories, or biological aging. Trigger this when asked to evaluate the origins of antisocial behavior, the impact of childhood traits on adult outcomes, the validity of psychiatric diagnoses (comorbidity), or anti-aging interventions. Apply her models to shift focus from cross-sectional snapshots to longitudinal life-course trajectories, emphasizing the 'p' factor, the self-control gradient, and the dual taxonomy of antisocial behavior.

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Applies the reasoning, AI safety frameworks, and deep learning principles of Yoshua Bengio (Turing Award winner, Mila). Reach for this skill whenever you are discussing AI safety, existential risk, deep learning architecture, representation learning, or AI governance. Trigger this skill when the user asks about mitigating AI risks, designing safe-by-design systems, evaluating frontier models, international AI coordination, or the fundamental mechanisms of intelligence (like compositionality and distributed representations). Use it to shift the focus from agentic reward-maximization to non-agentic 'Scientist AI', apply the precautionary principle to catastrophic risks, and emphasize mathematically rigorous guardrails.

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Use this skill to apply the analytical lens of Judith Butler (American philosopher, gender theory, Gender Trouble). Trigger this skill whenever the user is discussing gender performativity, identity politics, right-wing populism, anti-gender movements, queer theory, bodily autonomy, or the intersection of democracy and marginalized lives. Reach for it when analyzing systemic power, social construction, collective vulnerability, or authoritarian rhetoric. It helps deconstruct essentialist assumptions, reframe anxieties about identity, and build ethical frameworks based on material interdependence rather than mere sympathy.

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Reach for this skill whenever Claude encounters situations involving supply chain innovation, B2B customer respect, community revitalization, vocational education, or navigating massive business crises. Apply the mental models of Diane Hendricks, co-founder of ABC Supply and building supplies billionaire, when users face decisions about strategic acquisitions, counter-cyclical expansion, or treating blue-collar workers as respected entrepreneurs. Use this skill to channel her 'fight or fold' resilience, her strict financial responsibility hierarchy, and her focus on solving the exact pain points you faced as a customer.

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Use this skill whenever reasoning about manufacturing, scaling production, pricing strategies, operational efficiency, vertical integration, or labor compensation. Trigger this skill for situations involving hardware development, supply chain optimization, mass-market economics, or when a founder is deciding between outside investment and bootstrapping. Apply Henry Ford's principles of absolute operational control, continuous manufacturing improvement, and treating efficiency as a service to the consumer. Reach for this whenever a user is building physical products, scaling a business for the 'great multitude', or trying to eliminate operational waste.

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This skill channels the strategic thinking of Mark Zuckerberg, co-founder and CEO of Meta. Reach for this skill whenever the user is navigating rapid product iteration, scaling social platforms, open-source AI strategy, content moderation trade-offs, or long-term organizational management. It is highly effective for scenarios involving "The Hacker Way" (rapid prototyping), building community, handling intense public criticism, or deciding between open vs. closed ecosystems. Use this skill to apply his frameworks on decentralized testing, small group context sharing, and progressive AI integration, even if the user doesn't explicitly mention his name.

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Use this skill to apply the rigorous epidemiological reasoning of Julie E. Buring (epidemiologist and women's health trialist) to study design, clinical trial critiques, cardiovascular risk assessment, and evidence-based integrative medicine. Trigger this skill whenever you are evaluating medical literature, designing cohort studies or RCTs, assessing conflicting research findings, or analyzing cardiovascular risk factors (especially in women). Reach for this when users ask about the validity of supplements, the discrepancy between observational and randomized data, or how to future-proof a clinical registry.

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Use this skill whenever you need to reason about public health, epidemiology, preventive medicine, healthy aging, longevity, lifestyle vs. genetics, or dietary patterns. Kay-Tee Khaw, an epidemiologist at the University of Cambridge, focuses on population health and how modest lifestyle changes impact chronic disease. Trigger this skill when evaluating health interventions, discussing longevity, analyzing real-world health data, or giving advice on diet and lifestyle. Apply her frameworks to shift focus from extreme interventions and isolated nutrients toward whole-food patterns, population-level risk shifts, and the compression of morbidity.

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Use this skill whenever you are reasoning about public health policy, cancer prevention, epidemiological study design, clinical risk models, or weight management advice. This skill channels the thinking of Graham A. Colditz, epidemiologist at Washington University in St. Louis. Reach for this when evaluating lifestyle interventions, designing disease prevention programs, critiquing clinical prediction tools (e.g., AUC vs. clinical utility), or analyzing life-course risk accumulation. Apply his frameworks to bridge the "implementation gap" between scientific knowledge and societal action, prioritizing prevention over treatment and attainable weight maintenance over drastic weight loss.

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Applies the strategic, philanthropic, and operational frameworks of Andrew Carnegie, founder of Carnegie Steel. Use this skill whenever you are advising on wealth distribution, large-scale philanthropy, operational efficiency, cost control, legacy planning, or organizational leadership. Trigger this skill when users face decisions about charitable giving, managing inherited wealth, optimizing business costs in commodity markets, or structuring trusts and foundations. Apply his ruthless focus on cost-cutting, his belief in empowering self-improvement over direct handouts, and his philosophy that surplus wealth is a public trust.

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Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe. Reach for this skill when advising on consumer empowerment, navigating heavily regulated industries, preventative healthcare, data privacy, or disrupting entrenched systems. Use this when the user is dealing with misaligned industry incentives, facing regulatory hurdles, building a consumer-research flywheel, or managing a team through a post-launch 'trough of sorrow'. Apply her principles of 'speaking with data', treating users as partners, and pushing for decade-long systemic change from the outside.

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This skill channels the reasoning of Hannah Arendt, 20th-century political theorist and author of 'The Origins of Totalitarianism'. Use this skill whenever you are evaluating moral responsibility, analyzing systemic evil, distinguishing between power and violence, or assessing the nature of political action and freedom. Trigger it when discussing bureaucracy, thoughtlessness, the public vs. private realm, truth in politics, or when a user faces unprecedented moral dilemmas requiring 'thinking without a banister'. Apply her frameworks to critique historical determinism, defend factual truth, and analyze human plurality, even if the user does not explicitly name her.

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Use this skill whenever you are reasoning about large-scale scientific projects, genomics, bioethics, data infrastructure, or long-term medical translation. Eric S. Lander (geneticist, Broad Institute, Human Genome Project) provides a framework for hypothesis-free discovery, structuring "big science," and treating biology as an information science. Reach for this when the user is discussing open science, collaborative ecosystems, CRISPR/gene editing ethics, managing massive datasets, or setting realistic timelines for technological breakthroughs. Apply his principles to avoid the "lone genius" myth, prevent overpromising, and build foundational infrastructure that serves the broader community.

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