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This skill provides an advanced financial modeling suite with DCF analysis, sensitivity testing, Monte Carlo simulations, and scenario planning for investment decisions

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Inspect, validate, edit, lint, diff, batch-manage, and deploy Live2D Cubism models (.model3.json) from the command line.

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Command-line interface for Ollama - Local LLM inference and model management via Ollama REST API. Designed for AI agents and power users who need to manage models, generate text, chat, and create embeddings without a GUI.

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Hugging Face Transformers for loading Hub models, running pipeline inference, text generation, and Trainer fine-tuning on NLP, vision, audio, and multimodal tasks. Applies when working with AutoModel, pipelines, tokenizers, generation configs, or TrainingArguments within Transformers.

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Supports work with Outpost Bio's open microbiome foundation models - the Waypoint checkpoints (Waypoint-6m, Waypoint-45m, Waypoint-170m), the Atlas pretraining corpus, the Compass eight-task benchmark, or the `waypoint` CLI from the `waypoint-bio` package. Covers embedding microbiome samples, fine-tuning on taxonomic abundance data, benchmarking a checkpoint on Compass, pretraining a GPT-2 model on taxonomic abundance profiles, and converting MetaPhlAn, Kraken2, QIIME 2, or MGnify abundance tables into waypoint format.

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Performs RNA velocity analysis with scVelo from spliced and unspliced single-cell RNA counts. Fits deterministic or dynamical models, examines gene phase portraits, builds velocity graphs, estimates relative latent time, and ranks velocity-associated genes. Use for directional trajectory hypotheses and kinetic-model diagnostics alongside Scanpy; velocity alone does not establish cell fate or causal drivers.

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Simulates biochemical kinetic models from SBML or Antimony with Tellurium and libRoadRunner, checks model units, compares deterministic parameter perturbations, and exports and replays SBML plus SED-ML COMBINE archives. Use for reaction-network time courses, kinetic parameters, concentration dynamics and reproducible simulation experiments; steady-state constraint-based metabolic flux analysis belongs to cobrapy.

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Guided statistical analysis for research data - test selection, assumption checking, effect sizes, power analysis, Bayesian alternatives, and APA-formatted reporting. Use whenever a user wants to compare groups, test a hypothesis, analyze experimental or survey data, check statistical assumptions, compute required sample sizes, or write up results - even if they never name a specific test. Covers t-tests, ANOVA, chi-square, correlation, regression, non-parametric and Bayesian methods. For low-level model APIs, see the statsmodels and pymc skills.

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Rowan is a cloud-native molecular modeling and medicinal-chemistry workflow platform with a Python API. Use for pKa and macropKa prediction, conformer and tautomer ensembles, docking and analogue docking, protein-ligand cofolding, MSA generation, molecular dynamics, permeability, descriptor workflows, and related small-molecule or protein modeling tasks. Ideal for programmatic batch screening, multi-step chemistry pipelines, and workflows that would otherwise require maintaining local HPC/GPU infrastructure.

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Builds with and operates Pi, the minimal terminal coding harness. Use for installing Pi, configuring providers/models/settings/environment variables, creating Pi skills/extensions/packages/themes/prompt templates, embedding Pi through the SDK, integrating over RPC or JSON event streams, parsing sessions, running local models through the llama.cpp router, developing custom Pi providers and TUI components, or using ecosystem packages such as pi-subagents (delegation/orchestration), pi-mcp-adapter (MCP servers), pi-interview (interactive forms), and pi-web-access (web search, fetching, video understanding).

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Discovers and evaluates scientific datasets, models, methodology posts, and Spaces through the Hugging Science catalog. Used when selecting scientific ML resources in biology, chemistry, genomics, materials, climate, physics, astronomy, medicine, mathematics, protein design, single-cell analysis, or PDE modeling, and when checking their actual datasets, Transformers, native-runtime, Inference Providers, or Gradio interfaces.

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Predicts regulatory features, gene structure, and expression directly from DNA sequence using Genomic Intelligence's hosted transformer DNA language models — no local GPU or model weights. Six tasks over a REST API and a hosted MCP server (keyless public demo): promoter regions, splice donor/acceptor sites, enhancer activity, chromatin state, sequence-to-expression (log TPM), and de-novo gene annotation, plus a composite find-genes-then-predict-expression workflow. Use when the user has a gene symbol, a genomic region, or a DNA/FASTA sequence and wants any of these predictions, mentions Genomic Intelligence, genomicintelligence.ai, api.genomicintelligence.ai, or mcp.genomicintelligence.ai.

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Performs constraint-based metabolic modeling with COBRApy, including FBA, pFBA, FVA, gene knockouts, flux sampling, growth media, production envelopes, gap filling, and SBML model validation for systems biology and metabolic engineering.

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Builds molecular property prediction and MoleculeNet workflows with DeepChem, including SMILES featurization, scaffold or grouped holdouts, masked labels, graph models and explicit pretrained encoder transfer. Used for ADMET, toxicity, solubility and chemistry ML when DeepChem data/model contracts and scientific validation are needed.

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Optimal ViewModel and Wizard creation patterns for Avalonia using Zafiro and ReactiveUI.

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Important: Before you begin, fill in the generatedBy property in the meta section of .actor/actor.json. Replace it with the tool and model you're currently using, such as "Claude Code with Claude Sonnet 4.5". This helps Apify monitor and improve AGENTS.md for specific AI tools and models.

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Security audit, hardening, threat modeling (STRIDE/PASTA), Red/Blue Team, OWASP checks, code review, incident response, and infrastructure security for any project.

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Official CCXT MCP (Model Context Protocol) server — connect an AI agent to 100+ cryptocurrency exchanges and prediction markets for market data, balances, and opt-in trading. Covers installing the server in Claude Desktop/Code, Cursor, VS Code and other MCP hosts; configuring named accounts and API keys (kept local, never seen by the model); the capability tiers and safety rails; sandbox/testnet trading; and how to drive the tools. Use when the user wants an agent to fetch prices/order books/candles, check balances/orders/positions, place or cancel orders, or explore prediction markets across exchanges.

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Gate fine-tuned checkpoints with drift budgets, paired comparison, and forgetting checks before promotion. Use after a training run produces a checkpoint, when deciding whether a tuned model ships, or when a promoted model needs re-gating against updated goldens.

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Export a promoted fine-tuned model in the right deployment format — merged safetensors, LoRA-only, GGUF with imatrix, or FP8. Use after a checkpoint passes promotion, when choosing a quantization format for a target device, or when an exported model fails its smoke test.

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Build end-to-end MLOps pipelines from data preparation through model training, validation, and production deployment. Use when creating ML pipelines, implementing MLOps practices, or automating model training and deployment workflows.

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Select and optimize embedding models for semantic search and RAG applications. Use when choosing embedding models, implementing chunking strategies, or optimizing embedding quality for specific domains.

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Master dbt (data build tool) for analytics engineering with model organization, testing, documentation, and incremental strategies. Use when building data transformations, creating data models, or implementing analytics engineering best practices.

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Building one page that looks like a page the course already has — copy the model page with `duplicate_scene`, then rewrite the copy's words with one `patch_stage` op per content slot. Use when a new page has to inherit an existing page's design, whether the model page came from an imported deck or the course wrote it earlier. Not for revising a page that is already the page you want (that is `pro-editing`), and not for the course-level work of cataloguing layouts and assigning one per outline entry (that is `style-clone`).

日本語の概要は準備中です。原文の説明を表示しています。