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临床诊断思维 (临床诊断思维 / 临床推理 (Clinical Diagnostic Reasoning) — 医生『怎么想病』的元学科:从症状/体征/检查到诊断结论的认知操作系统,从业者(临床医生/住院医/规培生,尤其全科/急诊/大内科等以未分化主诉为生的科室)、医学生与医学教育者、诊断安全与质量改进研究者、以及做医疗 AI 辅助诊断产品的人的视角。覆盖: (a) 第一性张力 — **直觉模式识别 (System 1: illness scripts 疾病脚本 / pattern recognition / gestalt, 『资深人一眼认出 aunt Minnie』) ⇄ 分析性推理 (System 2: hypothetico-deductive 假设演绎 / Bayesian 概率更新)** 的 dual-process 双过程理论 (Kahneman→Croskerry/Norman 谱系), 资深≠更会分析而是『脚本库更大+校准更好』; 更深层论战 — **『认知去偏可教 (Croskerry: bias awareness / cognitive forcing strategies / diagnostic timeout) ⇄ 偏倚标签是马后炮、知识结构才是主因 (Norman/Sherbino/Monteiro: debiasing 干预 transfer 证据弱, bias 是 hindsight 标签)』** — 本行最核心学术对垒; 『概率思维 (验前概率 × 似然比 → 验后概率, Pauker-Kassirer test/treatment threshold 阈值模型) ⇄ 穷尽式排查 (rule-out everything / 防御性医疗 / VOMIT)』; 『临床 gestalt ⇄ 结构化临床决策规则 (Wells/PERC/HEART)』; 『诊断简约 Occam's razor ⇄ Hickam's dictum (病人可以同时得 N 个病)』; 『床旁体格检查复兴 (Verghese Stanford 25 / McGee 循证体检) ⇄ 影像检验替代床旁』; (b) 方法论正典 — illness script theory (Schmidt/Boshuizen: enabling conditions/fault/consequences 三段结构), problem representation + semantic qualifiers 问题表征与语义限定词 (Bowen NEJM 2006, 把病人翻成 one-liner), hypothetico-deductive model (Elstein 1978《Medical Problem Solving》: 早期假设生成+定向检验), Bayesian 工具箱 (sensitivity/specificity/LR/Fagan nomogram/SnNout-SpPin), threshold model (Pauker-Kassirer NEJM 1975/1980), 认知偏倚分类学 (anchoring/premature closure/availability/confirmation/base-rate neglect/search satisficing/diagnostic momentum — Croskerry 偏倚清单), 去偏与元认知策略 (diagnostic timeout/cognitive forcing/Ely checklist/calibration), schema-based reasoning (Clinical Problem Solvers schemas: 按 pivot 症状走分支), reflective practice 结构化反思 (Mamede/Schmidt), 诊断错误科学 (NAM 2015 报告定义 / Newman-Toker Big Three / Hardeep Singh e-triggers / SAFER Dx 框架); (c) 行业结构与角色 — 医学生→实习/住院医 (晨会 morning report/查房被 pimping/汇报训练)→主治 attending→master clinician (NEJM CPC discussant/晨会大师如 Dhaliwal); 配套生态: 医学教育者 (clinical reasoning curriculum + 评估: script concordance test/key features exam/OSCE), 诊断安全研究者 (SIDM/AHRQ), 诊断辅助与 CDS 工具开发者 (DDx generator/AI); (d) 核心工作流 — 数据采集 (病史为王 + 循证体检 + 针对性检验影像) → 问题表征 (one-liner + semantic qualifiers) → 鉴别诊断生成 (schema / 解剖定位法 / VINDICATE-M 病因筛, 按『常见可能 × 致命不能漏 can't-miss』双轴排序) → 假设定向检验 (按 LR 选检查 / 阈值决策) → working diagnosis + 安全网 (red flags 交代 / test of time / test of treatment) → 反馈校准 (follow-up / M&M / diagnostic timeout); 教学工作流: 晨会渐进披露汇报 / CPC / SNAPPS / one-minute preceptor / virtual morning report; AI 增强工作流 (2023-2026: LLM 鉴别诊断头脑风暴 / OpenEvidence 检索 / ambient scribe 释放认知带宽 + 自动化偏倚 guardrails); (e) 产出物 — one-liner, problem list, prioritized DDx, assessment & plan (按问题分层), 晨会/CPC 汇报, M&M 复盘, 诊断不确定性沟通 (『最可能是 X, 但出现 Y 红旗立刻回来』); (f) 教育与评估 — script concordance test / key feature exam / EPA / 里程碑; 中国语境: 人卫《诊断学》教材 / 执业医师考试 / 规培结业临床思维考核; (g) 争议/批判 — debiasing 之争 (Croskerry vs Norman-Sherbino『knowledge is the cure』, 去偏 RCT 效果弱 / bias 标签不可证伪), 诊断错误率数字之争 (『10-15%』经典估计 / Newman-Toker 79.5 万美国年严重伤害外推方法被质疑 / 尸检符合率), dual-process 二分被批过度简化 (连续谱 / 难以实证分离), 决策规则 vs gestalt (资深 gestalt 常不输 Wells 类规则 / 算法厌恶), vignette 研究外推性 + context/case specificity (推理高度内容绑定不可通用迁移 [Norman/Eva] — 对『教推理通用课』产业的根本批判), AI 辅助诊断 2023-2026 (GPT-4 在 NEJM CPC/vignette 追平或超医生 [Kanjee 2023 JAMA / Goh 2024 JAMA Netw Open『AI alone > physician+AI』悖论] / Google AMIE / OpenEvidence 爆发 vs 自动化偏倚 / 去技能化 / 真实环境验证缺失), 防御性医疗与过度检查 (incidentaloma 瀑布 / VOMIT), 体检衰亡之争, pimping 教学法争议; (h) 流派/思想谱系 — 决策科学/Bayesian 派 (Ledley-Lusted 1959 → Elstein/Kassirer/Sox/Pauker/Eddy → Brush) vs 认知心理/双过程派 (Kahneman-Tversky → Croskerry/Graber) vs 教育认知派 (Schmidt/Boshuizen illness scripts → Norman/Eva/Mamede/Durning 情境认知) vs 诊断安全/系统派 (NAM 2015 / Newman-Toker / Hardeep Singh / Graber-SIDM: 错误=系统×认知共因) vs 床旁临床派 (Osler 传统 → Tierney aphorisms / Verghese / McGee / Dhaliwal / Saint: 病史体检为王 + 刻意练习) vs AI/计算派 (INTERNIST-1/DXplain 专家系统 → Isabel → LLM 世代 Rodman/Topol)。不含: 具体专科治疗方案与手术决策深度 (足踝外科/种植牙等另有 skill), 中医辨证 (另有 skill), EBM 文献批判性评价方法学 (相关但本 skill 聚焦诊断推理本身), 护理诊断体系 (NANDA), 影像/病理知觉型读片训练 (相邻但独立), 精神科 DSM 结构化访谈细节, 医患沟通技巧全集 (只覆盖诊断不确定性沟通), 患者自查/自我诊断指

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DevOps 与站点可靠性工程 (SRE) — 平台 / 基础设施 / 可靠性工程师的认知操作系统, 覆盖软件交付 + 运维全生命周期 (CI/CD 与发布工程 trunk-based + 渐进式发布 canary/blue-green/feature flag + GitOps Argo CD/Flux / 基础设施即代码 Terraform/OpenTofu/Pulumi/Ansible + policy-as-code OPA / 容器与编排 Docker/Kubernetes + Helm/Kustomize + service mesh Istio/Linkerd / 可观测性 Prometheus + Loki + OpenTelemetry + Honeycomb + eBPF + RED/USE / SLO-SLI-error budget 与可靠性工程 Google SRE 学科 + 容量规划 + 优雅降级 / 事件管理与 on-call 事件指挥 + PagerDuty + runbook + 无指责复盘 + MTTR / 云平台与 FinOps AWS/GCP/Azure + 成本优化 + 弹性伸缩 / 平台工程与开发者体验 IDP + Backstage + golden path + Team Topologies / DevSecOps 与供应链安全 shift-left + SBOM + SLSA + sigstore + Vault / 韧性与混沌工程 fault injection + game day + 安全科学 / DORA 指标与工程效能 部署频率 + 变更前置时间 + 变更失败率 + Accelerate 研究 / 数据库与有状态运维 schema 迁移 + 备份容灾) — 不含 通用应用开发 / 纯云销售认证速成 / 'DevOps = 跑 Jenkins 的岗位' 窄化误解 / ITIL 工单文化传统运维 (旧范式仅做边界) / 把手工运维 ClickOps 当稳态 (是 toil, 本 skill 核心反模式) (DevOps & Site Reliability Engineering — the cognitive operating system of platform / infrastructure / reliability practitioners who own the full software delivery + operational lifecycle, covering (a) CI/CD & release engineering (build pipelines, trunk-based development, progressive delivery — canary / blue-green / feature flags, GitOps with Argo CD / Flux), (b) Infrastructure as Code (Terraform / OpenTofu, Pulumi, CloudFormation, Ansible, Crossplane — module design, state management, drift, policy-as-code OPA / Sentinel / Checkov), (c) containers & orchestration (Docker / OCI, Kubernetes — scheduling, networking CNI, storage CSI, operators / CRDs, Helm / Kustomize, service mesh Istio / Linkerd), (d) observability (the three pillars + beyond — metrics Prometheus / VictoriaMetrics, logs Loki / ELK, traces OpenTelemetry / Jaeger / Tempo, high-cardinality observability Honeycomb, eBPF, RED / USE methods, SLO-based alerting), (e) SLO / SLI / error budgets & reliability engineering (Google SRE discipline — service level objectives, error budget policy, toil budgets, capacity planning, load shedding, graceful degradation), (f) incident management & on-call (incident command, PagerDuty / Opsgenie, runbooks, blameless postmortems, MTTR / MTTD, error budget burn), (g) cloud platforms & FinOps (AWS / GCP / Azure well-architected, multi-region, cost optimization, autoscaling), (h) platform engineering & developer experience (internal developer platforms, Backstage, golden paths, self-service, Team Topologies), (i) DevSecOps & supply-chain security (shift-left, SAST / DAST, SBOM, SLSA, sigstore / cosign, secrets management Vault), (j) resilience & chaos engineering (chaos experiments, fault injection, game days, resilience engineering / safety science), (k) DORA metrics & engineering effectiveness (deployment frequency, lead time, change failure rate, MTTR, the Accelerate research), (l) databases & stateful operations (schema migrations, backups / DR, replication); NOT generic software development / app feature coding (是 平行学科, DevOps/SRE 关注 delivery + operability 不是 product feature), NOT pure cloud sales / certification cram without operational depth, NOT 'DevOps = a job title that runs Jenkins' 的窄化误解 (DevOps 是 文化 + 实践, SRE 是 Google 对 reliability 的工程化具体实现), NOT ITIL-heavy 传统运维 工单文化 (是 被 DevOps 取代的旧范式, 仅做边界标注), NOT manual ops / ClickOps as a steady state (是 toil, 本 skill 的核心反模式).) Master OS — automated mastery of DevOps & Site Reliability Engineering — the cognitive operating system of platform / infrastructure / reliability practitioners who own the full software delivery + operational lifecycle, covering (a) CI/CD & release engineering (build pipelines, trunk-based development, progressive delivery — canary / blue-green / feature flags, GitOps with Argo CD / Flux), (b) Infrastructure as Code (Terraform / OpenTofu, Pulumi, CloudFormation, Ansible, Crossplane — module design, state management, drift, policy-as-code OPA / Sentinel / Checkov), (c) containers & orchestration (Docker / OCI, Kubernetes — scheduling, networking CNI, storage CSI, operators / CRDs, He

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数据工程 — 数据平台从业者的认知操作系统, 覆盖把数据从源系统搬运成可靠 / 可查询 / 可信赖形态供分析 / ML / 数据产品消费的全生命周期 (生成 → 摄取 → 存储 → 转换 → 服务 + 安全/数据管理/DataOps/数据架构/编排/软件工程 六条暗流, Reis & Housley 框架): 摄取与集成 (批 + CDC 变更数据捕获 Debezium + EL 工具 Fivetran/Airbyte/Meltano/dlt + Kafka Connect + schema drift) / 存储与文件表格式 (对象存储数据湖 + 列存 Parquet/ORC/Arrow/Avro + 开放表格式 Apache Iceberg/Delta Lake/Apache Hudi + lakehouse + 分区/compaction) / 转换与建模 (ELT dbt/SQLMesh + Spark + 维度建模 Kimball + Inmon + Data Vault + 大宽表 OBT + 渐变维 SCD + 增量模型 + 语义/指标层) / 编排与工作流 (Apache Airflow/Dagster/Prefect/Mage/Kestra/Apache DolphinScheduler + DAG + 幂等 + 回填 backfill + 数据资产调度) / 批流与实时 (Apache Kafka/Apache Flink/Spark Structured Streaming/Kinesis/Pulsar/Redpanda + Lambda vs Kappa + watermark/窗口/exactly-once + 流式 SQL Materialize/RisingWave + 实时 OLAP ClickHouse/Apache Druid/Apache Pinot/StarRocks/Apache Doris) / 数仓与查询引擎 (Snowflake/BigQuery/Redshift/Databricks SQL/Trino/Presto/DuckDB/Polars + 存算分离 + MPP) / 数据质量测试与可观测性 (dbt tests/Great Expectations/Soda + 数据契约 + Monte Carlo data downtime + 新鲜度/量/schema 异常检测) / 数据治理编目与血缘 (DataHub/Amundsen/OpenMetadata/Unity Catalog + 列级血缘 + PII 分类 + 访问控制 + GDPR) / DataOps 与可靠性 (数据 CI/CD + 转换版本控制 + 环境隔离 + 幂等重处理 + 数据 SLA/SLO + 计算存储 FinOps) / 数据架构范式 (现代数据栈 + lakehouse + data mesh + data fabric + 去中心化 vs 中心化所有权) / 分析工程角色 (dbt 时代连接数据工程与分析的桥) — 不含 数据科学/ML 建模本身 (是下游消费者) / BI 仪表盘制作 (serving 下游) / 数据分析报表为终点 / 'data engineer = 跑 Hadoop 的' 过时窄化 / 通用后端应用开发 (平行学科) (Data Engineering — the cognitive operating system of practitioners who design, build, and operate the data platform: moving data from source systems into reliable, queryable, trustworthy form for analytics / ML / products, covering (a) the data engineering lifecycle (generation → ingestion → storage → transformation → serving, with the undercurrents security / data management / DataOps / data architecture / orchestration / software engineering — Reis & Housley framing), (b) ingestion & integration (batch + CDC change-data-capture with Debezium, EL tools Fivetran / Airbyte / Meltano / dlt, Kafka Connect, API + file + database sources, schema drift handling), (c) storage & file/table formats (object storage data lakes, columnar formats Parquet / ORC / Arrow / Avro, open table formats Apache Iceberg / Delta Lake / Apache Hudi, lakehouse architecture, partitioning / compaction / Z-ordering), (d) transformation & modeling (ELT with dbt / SQLMesh, Spark, dimensional modeling Kimball, Inmon CIF, Data Vault, One Big Table / wide tables, normalization vs denormalization, slowly changing dimensions, incremental models, the semantic / metrics layer), (e) orchestration & workflow (Apache Airflow, Dagster, Prefect, Mage, Kestra, Apache DolphinScheduler, DAGs, idempotency, backfills, data-aware / asset-based scheduling), (f) batch vs streaming & real-time (Apache Kafka, Apache Flink, Spark Structured Streaming, Kinesis / Pulsar / Redpanda, the Lambda vs Kappa debate, watermarks / windowing / exactly-once, streaming SQL Materialize / RisingWave, real-time OLAP ClickHouse / Apache Druid / Apache Pinot / StarRocks / Apache Doris), (g) warehouses & query engines (Snowflake, BigQuery, Redshift, Databricks SQL, Trino / Presto, DuckDB, Polars, decoupled storage & compute, MPP), (h) data quality, testing & observability (dbt tests, Great Expectations, Soda, data contracts, Monte Carlo / data downtime, freshness / volume / schema anomaly detection, unit / integration testing of pipelines), (i) data governance, catalog & lineage (DataHub, Amundsen, OpenMetadata, Unity Catalog, column-level lineage, PII / data classification, access control, GDPR / data privacy), (j) DataOps & reliability (CI/CD for data, version control of transformations, environments, idempotent reprocessing, SLAs / SLOs for data, cost / FinOps for compute & storage), (k) data architecture paradigms (modern data stack, data lakehouse, data mesh, data fabric, decentralized vs centralized ownership), (l) the analytics engineering role (the dbt-era bridge between data engineering and analysis); N

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Composes single-file HTML artifacts (PR review writeups, status reports, incident postmortems, slide decks, design systems, prototypes, flowcharts, module maps, feature explainers, kanban boards, prompt tuners) from a small JSON spec instead of hand-written HTML/CSS/JS. Use when the user asks to "compare options side-by-side", requests an HTML version of a report or review or deck, asks for a flowchart, status update, postmortem, design system reference, interactive prototype, custom editor — or explicitly says "HTML artifact", "single HTML file", "self-contained HTML". Skip for ad-hoc HTML snippets (forms, emails, embedded widgets) where there's no template fit.

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Master advanced AgentDB features including QUIC synchronization, multi-database management, custom distance metrics, hybrid search, and distributed systems integration. Use when building distributed AI systems, multi-agent coordination, or advanced vector search applications.

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Draws an activity flow / system architecture diagram as ONE self-contained, INTERACTIVE HTML+SVG page (2-pane app layout — left: diagram, default fit-to-view with zoom/pan; right: sidebar with explainer cards), styled like a real hand-drawn enterprise doc (Stripe/AWS-docs style — real brand logos for MongoDB/Odoo/n8n/etc. from a bundled Simple Icons library, neutral white boxes, sans-serif, no "AI neon" look), scroll-to-zoom, auto light/dark with a toggle button — clicking a flow (a legend chip, a line, or a step badge) highlights that flow with traveling dots along the arrows in their direction, a ping at the destination box, and a sidebar panel that slides out, while everything else dims; two-way arrows (OUT = solid blue / RETURN = dashed green) carry numbered step badges, colored by semantic meaning (red = auth checkpoint, purple = scheduled flow, amber = data pipeline), a small "hop" arc where two lines are forced to cross, dashed group regions, one explainer card per flow in the right sidebar. Use this skill ANY TIME the user wants to "draw a diagram", "draw a flow", "draw a system diagram", "redraw this so it's easier to follow", "interactive diagram", "two-way diagram", "request/response flow", "make a free-form HTML diagram" — even if they never say the word HTML. Especially good when both the request direction AND the response direction need to be shown, or when a templated tool (archify, mermaid) is too rigid. Do NOT use for data charts (bar/line/pie), and do not use when the user asks specifically for archify or mermaid.

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Create a consistent spacing system based on a base unit with contextual application rules.

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Define a motion system with duration tokens, easing vocabulary, and reduced-motion handling for consistent animation across a product.

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Create adoption strategies and materials to drive design system usage across teams.

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Create an icon system specification covering grid, sizing, naming, categories, and implementation guidance.

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Email triage system that handles both one-time setup and recurring triage in a single skill. Auto-detects state: if no knowledge base exists at ${WORKSPACE}/Email/, runs an 8-section onboarding interview (grill-me discipline, one question at a time) to build a 7-file personalized KB, then offers to run triage immediately. If the KB already exists, skips setup and goes straight to triage — searches recent emails, classifies them via the user's taxonomy, researches new senders, generates TAKE IT/WORTH/PASS/FLAG recommendations, drafts replies (NEVER sends), delivers a report, and updates the KB. Use with 'update' argument to refresh preferences. Setup triggers: 'set up my inbox', 'configure inbox triage', 'set up my email system', 'configure email triage', 'build my email knowledge base', 'initialize email management'. Triage triggers: 'triage my inbox', 'inbox triage', 'check my email', 'run email triage', 'process my inbox', 'what's new in my email', 'handle my email', 'email triage'.

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Define how a design system evolves — contribution models, versioning, change management, and deprecation.

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Build a comprehensive color system with palette generation, semantic mapping, and accessibility compliance.

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Analyze images, websites, and Figma files to extract their design and generate a `design.md` with token system, component inventory, and reconstruction notes. Use this skill whenever the user wants to understand, document, replicate, or audit the design of something visual: a screenshot, a URL, a Figma link, a Pinterest reference, a mockup, a competitor's site, a component, a dashboard, a landing page. Also when they ask 'extract the design system from X', 'document the style of Y', 'analyze this visually', 'convert this image into tokens', 'help me replicate this design', 'what palette does this site use', 'how is this built'. Also for single elements: 'copy this navbar', 'recreate this illustration', 'give me a prompt to regenerate this graphic' — element mode outputs a focused element.md, with token-grounded image-model prompts when the element is visual art. If the user brings any visual source and wants to understand it at a design level — this skill should activate.

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Extract a design system from a screenshot (PNG/JPG/WEBP) or a live URL and produce a schema-compliant `design.v1.json` file plus a ready-to-use agent prompt for applying the design to any website/app. When run inside the sleek-ui repository, offers to add the extracted design to the public catalog as a PR — updating `public/designs/`, `src/data/designs/`, `src/data/designs.ts`, and generating a preview. Use when users ask to "extract a design from this screenshot", "clone this site's design", "reverse-engineer the design tokens", "reskin my app to look like {site}", "generate a sleek-ui design from this URL", or provide an image/URL and want a reusable design system.

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Open Analytics' design language, extracted from the shipped product: an ink-derived neutral system, squircle surface anatomy, one small spring vocabulary, pixel-matched skeletons, and a plain-spoken copy voice, with type-checked component recipes. Use this whenever you build or restyle a dashboard, SaaS app, analytics UI, settings screen, onboarding flow, or marketing/landing page that should feel calm, dense and native, and whenever the user mentions Open Analytics' look, 'clean SaaS design', cards, dropdowns, tab bars, empty states, skeletons, or UI animation quality, even if they never say the words 'design system'.

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Master advanced AgentDB features including QUIC synchronization, multi-database management, custom distance metrics, hybrid search, and distributed systems integration. Use when building distributed AI systems, multi-agent coordination, or advanced vector search applications.

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Use this skill when reasoning about deep tech commercialization, biomedical engineering, drug delivery, material design, or overcoming institutional skepticism. Robert Langer, MIT professor and pioneer of drug delivery systems, approaches problems through first-principles engineering, interdisciplinary convergence, and relentless perseverance against consensus. Trigger this skill whenever the user is evaluating high-risk/high-reward research, deciding between incremental vs. paradigm-shifting impact, spinning out academic discoveries into startups, or designing physical/biological systems from scratch. Apply his frameworks to navigate patenting, funding, and translating lab science into real-world impact.

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Applies the foundationalist reasoning and methodological doubt of René Descartes (17th-century French rationalist philosopher). Use this skill whenever the user is questioning fundamental assumptions, seeking absolute certainty in a decision, dismantling flawed systems, or trying to rebuild a project from first principles. Trigger this skill for topics involving epistemology, rationalism, radical doubt, systemic reconstruction, or separating objective truth from sensory illusion. Reach for this whenever a user needs to cut through probabilities and consensus to find an indubitable 'Archimedean point' to build upon.

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Reach for this skill whenever you are discussing reinforcement learning, agentic AI systems, AI alignment, continual learning, or the philosophical limits of large language models. This skill channels the thinking of Richard S. Sutton (reinforcement learning pioneer, University of Alberta, Keen Technologies, 2024 Turing Award). Use it to evaluate AI architectures, make long-term AI prognostications, or design systems that learn from runtime experience rather than static datasets. Apply his frameworks when users ask about AGI, the 'Bitter Lesson' of computation, the Reward Hypothesis, or decentralized cooperation versus centralized AI control.

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Applies the reasoning of Zhong Lin Wang (nanotechnology pioneer, Georgia Tech) to problems involving energy harvesting, IoT power scaling, sensor networks, and fundamental physics applications. Reach for this skill whenever the user is discussing self-powered systems, scaling distributed hardware, overcoming battery bottlenecks, or translating fundamental scientific phenomena (like static electricity or mechanical strain) into novel engineering applications. It is highly relevant for hardware roadmapping, optoelectronics, piezotronics, and challenging established scientific assumptions (like classical Maxwell's equations) to model dynamic systems.

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Applies the product philosophy and leadership frameworks of Steve Jobs, co-founder and CEO of Apple Inc. Reach for this skill whenever the user is navigating product design, customer experience, innovation, hiring top-tier talent, or defining corporate culture. Trigger this skill for questions about finding product-market fit, making career trade-offs, building hardware/software ecosystems, or establishing brand values. Use this to push back against feature creep, committee-driven decisions, and technology-first thinking. Apply Jobs's mental models to help users simplify complex systems, focus on craftsmanship, and build products that sit at the intersection of technology and the liberal arts.

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Applies the reasoning of David Silver, lead researcher on AlphaGo and AlphaZero at DeepMind, to problems of AI design, reinforcement learning, and open-ended discovery. Use this skill whenever you are designing AI systems, evaluating learning algorithms, balancing exploration vs. exploitation, choosing research problems, or discussing how to break past human performance ceilings. Reach for this whenever the user asks about self-play, Monte-Carlo Tree Search, tabula rasa learning, AGI, or moving from human-curated data to autonomous experience. It helps shift the focus from hardcoding human knowledge to building systems that learn for themselves.

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Applies the strategic frameworks and mental models of Anne Wojcicki, co-founder and CEO of 23andMe. Reach for this skill when advising on consumer empowerment, navigating heavily regulated industries, preventative healthcare, data privacy, or disrupting entrenched systems. Use this when the user is dealing with misaligned industry incentives, facing regulatory hurdles, building a consumer-research flywheel, or managing a team through a post-launch 'trough of sorrow'. Apply her principles of 'speaking with data', treating users as partners, and pushing for decade-long systemic change from the outside.

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