「pact」の検索結果

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

Compact the session into gitignored `.codeconductor/sessions/handoff.md` (redact secrets).

日本語の概要は準備中です。原文の説明を表示しています。

First-principles assumption auditor. Classifies each hidden assumption (fact / convention / belief / interest-driven), ranks by fragility × impact, and rebuilds conclusions from verified premises. Bilingual: auto-detects Chinese or English.

日本語の概要は準備中です。原文の説明を表示しています。

Monospace-driven, matrix-inspired design with high-contrast elements, compact density, and a hacker-chic aesthetic.

日本語の概要は準備中です。原文の説明を表示しています。

Classic block-game inspired design with playful colors, bold display fonts, and compact, high-energy layouts.

日本語の概要は準備中です。原文の説明を表示しています。

Build an impact-based regression selection with explicit traceability, inclusions, exclusions, and limitations.

日本語の概要は準備中です。原文の説明を表示しています。

Select traceable regression coverage from change impact, affected risks, criteria, dependencies, and prior defects rather than execution convenience.

日本語の概要は準備中です。原文の説明を表示しています。

Use when the user, inside an Orca terminal, asks Hermes to resolve, dispatch, orchestrate or supervise GitHub issues with Orca workers — 'orquestrar as issues 12, 15 e 18 no Orca', 'despachar as issues com label ready', 'coordenar workers do Orca para estas issues', or to resume such a Run after compaction. Do NOT use for a single unsupervised hand-off to another agent (Orca CLI directly), for working on one issue in this session (pwdev-feat feat-loop), or outside Orca.

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Produces a compact KPI digest showing how key metrics changed over a period and what's driving the movement. Use this skill when someone asks for a performance summary, a weekly recap, a morning briefing, a KPI update, or any variation of "how did we do this week/month." Also trigger for "give me a performance overview," "what moved in the last 7 days," "pull our AA KPI report," or "summarize our metrics."

日本語の概要は準備中です。原文の説明を表示しています。

Produces a compact KPI digest showing how key metrics changed over a period and what's driving the movement. Use this skill when someone asks for a performance summary, a weekly recap, a morning briefing, a KPI update, or any variation of "how did we do this week/month." Also trigger for requests like "give me a performance overview," "what moved in the last 7 days," "pull our KPI report," or "summarize our metrics."

日本語の概要は準備中です。原文の説明を表示しています。

Explain Ponytail's intended tradeoffs and measurement boundary. It does not estimate code, cost, or speed savings for the current repository. One-shot display, not a persistent mode. Trigger: ponytail-gain, "ponytail gain", "what does ponytail save", "show ponytail impact", or "ponytail scoreboard".

日本語の概要は準備中です。原文の説明を表示しています。

Compact the current conversation into a handoff document for another agent to pick up.

日本語の概要は準備中です。原文の説明を表示しています。

ATM 版本升級與開源 release train 工作流。USE FOR: ATM frameworkVersion 升級、release impact 分類、SemVer 決策、CODEOWNERS / changeset / release gate 檢查、ATM upstream release docs 維護。

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Apply one logical code change with mandatory impact mapping, git snapshot, verification, and automatic revert on failure. Load when the user asks for a safe edit, verified change, one change at a time with rollback, or codespine-style edit loop. Also triggers on "safe change", "edit with verification", "don't break the build", "revert if tests fail", or any non-trivial code edit where blast radius matters. Always runs dependency-mapping first. Pairs with incremental-implementation for multi-slice work; this skill is one atomic verify cycle per invocation.

日本語の概要は準備中です。原文の説明を表示しています。

Compress bloated project or global memory while preserving decisions, rationale, revisit triggers, provenance, and active user preferences. Load when memory exceeds budget, global memory is too large, session logs are repetitive, or before appending to an over-budget memory file.

日本語の概要は準備中です。原文の説明を表示しています。

Orchestrate persistent agent memory across coding sessions, repos, and tools. Load when the user asks to remember, recall context, save project memory, create a handoff, manage global memory, update memory, compact memory, audit memory, forget memory, continue from prior sessions, or before commit/push/git operations that checkpoint project state.

日本語の概要は準備中です。原文の説明を表示しています。

Map symbol dependencies, callers, and blast radius before editing code. Load when the user asks what depends on a symbol, what breaks if they change something, blast radius of a change, reverse dependencies, or which tests cover a function. Also triggers on "who calls this", "impact of changing", "dependency map", "what uses this", "find callers", or before any non-trivial edit when safe-change is not yet active. Pairs with codebase-understanding for broad architecture; this skill is symbol-scoped and edit-gated.

日本語の概要は準備中です。原文の説明を表示しています。

You bring the third dimension to the web. You know when 3D enhances and when it's just showing off. You balance visual impact with performance. You make 3D accessible to users who've never touched a 3D app. You create moments of wonder without sacrificing usability.

日本語の概要は準備中です。原文の説明を表示しています。

Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to understand which MVR violations disqualify a driver under federal rules. Covers § 391.15 disqualifications, varying state rules, and CSA impact.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when a driver receives an out-of-service (OOS) violation. Covers the immediate compliance, paperwork retention, and CSA impact.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a carrier asks whether to buy or lease their next tractor (or trailer), comparing full-service lease (Ryder, Penske, NationaLease), capital lease, finance lease, walk-away open-end lease, or cash purchase. Covers tax treatment, residual risk, maintenance bundling, balance-sheet impact, and cash-flow modeling.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about driver fatigue management — circadian rhythm impact on driving, recognizing fatigue, fatigue risk management programs (FRMS), night driving safety, microsleep recognition, drowsiness detection technology, and how HOS rules relate to actual fatigue (and why 11-hour driving is risky even when legal). Reference FMCSA Fatigue Management research.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a carrier asks about autonomous trucks — current state of Level 4 development, major programs (Aurora, Kodiak, Plus, Waymo Via, Embark history), regulatory status, operational implications, hub-to-hub model, driver impact, insurance, and what carriers should be doing now (or not doing) to prepare.

日本語の概要は準備中です。原文の説明を表示しています。