「sso」の検索結果

Maps GWAS-implicated loci to candidate effector (causal) genes by integrating variant-to-gene (V2G) features via Open Targets L2G (Mountjoy 2021), MAGMA gene-based association (de Leeuw 2015), FUMA SNP2GENE, cS2G combined SNP-to-gene scores (Gazal 2022), Polygenic Priority Scores (PoPS, Weeks 2023), FLAMES, INQUISIT, DEPICT, and enhancer-gene predictors (ABC, ENCODE-rE2G). Use when narrowing a GWAS lead locus to a candidate causal gene, picking between proximity, eQTL-based, and similarity-based prioritizers, integrating multi-evidence streams (fine-mapping, colocalization, ABC enhancer-gene, distance, chromatin), reconciling discordant L2G vs PoPS calls, prioritizing tissue-specific eQTL evidence, or triangulating across at least three independent lines of evidence for a publication-grade effector-gene nomination.

日本語の概要は準備中です。原文の説明を表示しています。

Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

日本語の概要は準備中です。原文の説明を表示しています。

Identifies super-enhancers from H3K27ac, MED1, or BRD4 ChIP-seq using ROSE, ROSE2, LILY, HOMER -style super, and ENCODE dELS cross-referencing. Handles peak stitching parameters, ranking choices, hockey-stick inflection, marker choice (H3K27ac vs MED1/BRD4), and cross-condition comparison with spike-in normalization. Constructs core regulatory circuitry (Saint-Andre 2016) from SE-encoded TFs. Use when identifying cell-identity / cancer-associated regulatory domains, comparing super-enhancers between conditions, identifying master transcription factor networks, or predicting BET-inhibitor responsiveness.

日本語の概要は準備中です。原文の説明を表示しています。

Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance, g-computation/standardisation for marginal effects, modified Poisson for RR, Brant test for proportional odds, Firth penalty for separation, and Hauck-Donner detection. Use when modeling binary or ordinal endpoints in confirmatory or exploratory clinical trials.

日本語の概要は準備中です。原文の説明を表示しています。

Detect and adjust for horizontal pleiotropy in two-sample Mendelian randomization by distinguishing uncorrelated (UHP) from correlated (CHP) pleiotropy and choosing among Egger, MR-PRESSO, MR-RAPS, CAUSE, LHC-MR, LCV, MR-Clust, MR-Mix, and contamination-mixture methods. Use when validating an MR causal claim, running the STROBE-MR sensitivity battery, suspecting a shared heritable confounder, working under weak-instrument or polygenic-exposure regimes, or reconciling discordant estimates across robust methods.

日本語の概要は準備中です。原文の説明を表示しています。

Resolves GWAS associations to candidate causal variants and credible sets via SuSiE, susie_rss, FINEMAP, CAVIAR, DAP-G, PAINTOR, PolyFun, SuSiEx, MultiSuSiE, and FOCUS. Use when narrowing a GWAS lead SNP to a 95 percent credible set, choosing between in-sample and reference LD, calibrating non-sparse loci with SuSiE-inf or FINEMAP-inf, integrating functional priors via PolyFun, fine-mapping across ancestries with SuSiEx, diagnosing LD mismatch via estimate_s_rss and kriging_rss, handling HLA or long-range LD, or feeding credible sets into coloc.susie for colocalization.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when buying another carrier and inheriting their drivers' DQF library. Covers the legal transfer of DQ records, what new owner must verify, and gaps that commonly require remediation.

日本語の概要は準備中です。原文の説明を表示しています。

Working playbook preloaded into the reviewer helper; the coach updates its Lessons after each round. Use only when acting as reviewer or coaching it. NOT for writing a verifier brief (use subagent-dispatch).

日本語の概要は準備中です。原文の説明を表示しています。

Working playbook preloaded into the researcher helper; the coach updates its Lessons after each round. Use only when acting as researcher or coaching it. NOT for general research tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Bringing an existing table onto the platform base standard. Use when asked to canonicalize, retrofit, or 'Wave 3' a table, run apply_rls or an org backfill, retire a bespoke *_versions table, or move it onto platform comments/associations/permissions. NOT for a schema move (use db-move-table-schema).

日本語の概要は準備中です。原文の説明を表示しています。

Working playbook preloaded into the browser-tester helper; the coach updates its Lessons after each round. Use only when acting as browser-tester or coaching it. NOT for general UI work (use matrx-frontend's browser-testing doc).

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_LogPrint (auto-generated, category: vfunc). Locate CEngineServer::LogPrint in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_LogPrint, CEngineServer::LogPrint

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_ClientPrintf (auto-generated, category: vfunc). Locate CEngineServer::ClientPrintf in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_ClientPrintf, CEngineServer::ClientPrintf

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServiceMgr_GetActiveLoopClientServerMode (auto-generated, category: func). Locate CEngineServiceMgr_GetActiveLoopClientServerMode in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServiceMgr_GetActiveLoopClientServerMode, CEngineServiceMgr_GetActiveLoopClientServerMode

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_ClientPrintf-decompiles (auto-generated, category: vfunc). Locate CEngineServer::ClientPrintf in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_ClientPrintf-decompiles, CEngineServer::ClientPrintf

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineClient_GetStatsAppID (auto-generated, category: vfunc). Locate CEngineClient::GetStatsAppID in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineClient_GetStatsAppID, CEngineClient::GetStatsAppID

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_ClientCommandKeyValues (auto-generated, category: vfunc). Locate CEngineServer::ClientCommandKeyValues in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_ClientCommandKeyValues, CEngineServer::ClientCommandKeyValues

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_SetFakeClientConVarValue (auto-generated, category: vfunc). Locate CEngineServer::SetFakeClientConVarValue in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_SetFakeClientConVarValue, CEngineServer::SetFakeClientConVarValue

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_GetAchievementMgr (auto-generated, category: func). Locate CEngineServer_GetAchievementMgr in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_GetAchievementMgr, CEngineServer_GetAchievementMgr

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_ClientCommand (auto-generated, category: vfunc). Locate CEngineServer::ClientCommand in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_ClientCommand, CEngineServer::ClientCommand

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_GetClientSteamID (auto-generated, category: func). Locate CEngineServer_GetClientSteamID in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_GetClientSteamID, CEngineServer_GetClientSteamID

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_ChangeLevel-noinline (auto-generated, category: vfunc). Locate CEngineServer::ChangeLevel in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_ChangeLevel-noinline, CEngineServer::ChangeLevel

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_ChangeLevel-inlined (auto-generated, category: vfunc). Locate CEngineServer::ChangeLevel in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_ChangeLevel-inlined, CEngineServer::ChangeLevel

日本語の概要は準備中です。原文の説明を表示しています。

Agent fallback for CEngineServer_SetFrameTimeAmnesty (auto-generated, category: vfunc). Locate CEngineServer::SetFrameTimeAmnesty in the CS2 engine module via IDA Pro MCP and emit a fresh, minimal-unique artifact. The deterministic preprocessor could not resolve this symbol on the current gamever - your job is the re-sign. Trigger: CEngineServer_SetFrameTimeAmnesty, CEngineServer::SetFrameTimeAmnesty

日本語の概要は準備中です。原文の説明を表示しています。