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Run an attorney-facing knockout/availability trademark search across the United States and Canada. Use whenever a user (founder, client, or attorney) asks whether a brand, mark, name, logo, slogan, or product name is "available," "free to use," "clearable," or "already taken" — or asks Claude to "search the trademark register," "check USPTO," "check CIPO," "do a knockout search," "clearance search," "availability search," or "see if [mark] is trademarked." Trigger even when the user phrases it casually ("can I call my company X?", "is this name taken?"). Covers federal USPTO (TESS/TSDR), federal Canada (CIPO), common-law/web/state, and WIPO Madrid international. Output is a knockout availability memo with green/yellow/red verdict for attorney review. Includes professional-responsibility gating (AI-use disclosure, conflict check, scope confirmation) before substantive analysis. Not legal advice — produces work product for attorney sign-off.

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Reviews or drafts the agreement that pays an employee to settle their claims — and flags the statutory conditions that decide whether it actually binds them. Works under s.203 ERA 1996 for England & Wales. Flags apparent s.203 condition gaps for a solicitor to confirm (writing, specific complaints, independent adviser, identification, insurance, statement of conditions), drafts the substantive terms (sum, tax characterisation, confidentiality, references, restrictive covenants, indemnities), and surfaces enforceability risks. Does not rule on validity and is not legal advice. Use when the user says 'review this settlement agreement', 'draft a settlement agreement', 'compromise agreement' (old term), or asks whether an agreement is binding.

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Classify AI systems under the EU AI Act (Regulation (EU) 2024/1689) and determine compliance obligations. Use when asked to assess AI risk level, check if an AI system is prohibited, determine high-risk status, identify GPAI model obligations, map provider/deployer responsibilities, or build an AI Act compliance roadmap. Covers the full classification decision tree (Prohibited → High-Risk → Limited → Minimal → GPAI), obligations by role (provider, deployer, importer, distributor), compliance timelines, and DACH-specific considerations (German works council, BaFin, BSI, BNetzA). Triggers on phrases like "classify this AI system", "is this high-risk under the AI Act", "AI Act risk assessment", "EU AI Act compliance", "prohibited AI practice", "GPAI obligations", "AI Act timeline".

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Use when a user asks what the EU Cyber Resilience Act (CRA) means for their product, whether and when they must report a vulnerability or incident, or what a specific CVE triggers legally. Maps a product with digital elements to CRA scope, product classification, Annex I vulnerability-handling duties, and Article 14 reporting obligations — every legal claim cited from official regulation text fetched live through the Ansvar Gateway MCP connector, joined with live CVE / CISA-KEV / EPSS vulnerability intelligence from the same connector.

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When your bar comes asking "show me how you billed AI-assisted work" — and ABA 512, Florida 24-1, California, New York, and DC all have opinions out — you need an artifact that survives review. billable-time produces it. From your Claude Code session logs, it drafts reviewable time entries plus a printable HTML audit packet with: SHA-256 chain of evidence (source files + matter.yml + active disclosure pack + verifiable artifact self-hash), attorney identity and signature block, a bar-opinion disclosure pack with starter language for five jurisdictions, and content-aware deterministic narratives derived from filename and tool shape — never from prompt text by default. The tool refuses to bill on its own. --strict mode refuses to ship the artifact if any audit invariant fails (broad routes, missing attorney, missing/unverified disclosure). Comes as a Node CLI and a self-contained browser version (no backend; JSONL never leaves the page). 15 invariant tests verify the contract. AGPL-3.0.

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Expert blueprint for mobile platforms (Android/iOS) covering touch controls, virtual joysticks, responsive UI, safe areas (notches), battery optimization, and app store guidelines. Use when targeting mobile releases or implementing touch input. Keywords mobile, Android, iOS, touch, InputEventScreenTouch, virtual joystick, safe area, battery, app store, orientation.

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Expert blueprint for mobile platforms (Android/iOS) covering touch controls, virtual joysticks, responsive UI, safe areas (notches), battery optimization, and app store guidelines. Use when targeting mobile releases or implementing touch input. Keywords mobile, Android, iOS, touch, InputEventScreenTouch, virtual joystick, safe area, battery, app store, orientation.

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Use when building character abilities — Resource-based abilities with cost/cooldown/cast, buffs/debuffs, stat modifiers, gameplay tags, and HUD binding

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The analysis and visualization of alternative splicing (AS) events from RNA sequencing data remains challenging. SpliceWiz is a user-friendly and performance-optimized R package for AS analysis, by processing alignment BAM files to quantify read counts across splice junctions, IRFinder-based intron retention quantitation, and supports novel splicing event identification. We introduce a novel visualization for AS using normalized coverage, thereby allowing visualization of differential AS across

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Tools for LiP peptide and protein significance analysis. Provides functions for summarization, estimation of LiP peptide abundance, and detection of changes across conditions. Utilizes functionality across the MSstats family of packages.

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ProteoDisco is an R package to facilitate proteogenomics studies. It houses functions to create customized (variant) protein databases based on user-submitted genomic variants, splice-junctions, fusion genes and manual transcript sequences. The flexible workflow can be adopted to suit a myriad of research and experimental settings.

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The ORFhunteR package is a R and C++ library for an automatic determination and annotation of open reading frames (ORF) in a large set of RNA molecules. It efficiently implements the machine learning model based on vectorization of nucleotide sequences and the random forest classification algorithm. The ORFhunteR package consists of a set of functions written in the R language in conjunction with C++. The efficiency of the package was confirmed by the examples of the analysis of RNA molecules fr

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The package comprises a set of pretrained machine learning models to predict basic immune cell types. This enables all users to quickly get a first annotation of the cell types present in their dataset without requiring prior knowledge. scAnnotatR also allows users to train their own models to predict new cell types based on specific research needs.

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Provides basic utility functions for performing single-cell analyses, focusing on simple normalization, quality control and data transformations. Also provides some helper functions to assist development of other packages.

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Classes and statistical methods for large SNP association studies. This extends the earlier snpMatrix package, allowing for uncertainty in genotypes.

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Zenith performs gene set analysis on the result of differential expression using linear (mixed) modeling with dream by considering the correlation between gene expression traits. This package implements the camera method from the limma package proposed by Wu and Smyth (2012). Zenith is a simple extension of camera to be compatible with linear mixed models implemented in variancePartition::dream().

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SGC is a semi-supervised pipeline for gene clustering in gene co-expression networks. SGC consists of multiple novel steps that enable the computation of highly enriched modules in an unsupervised manner. But unlike all existing frameworks, it further incorporates a novel step that leverages Gene Ontology information in a semi-supervised clustering method that further improves the quality of the computed modules.

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The sva package contains functions for removing batch effects and other unwanted variation in high-throughput experiment. Specifically, the sva package contains functions for the identifying and building surrogate variables for high-dimensi

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Implements low-level utilities for single-cell trajectory analysis, primarily intended for re-use inside higher-level packages. Include a function to create a cluster-level minimum spanning tree and data structures to hold pseudotime infere

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A robust and outlier-aware method for testing differential tissue composition from single-cell data. This model can infer changes in tissue composition and heterogeneity, and can produce realistic data simulations based on any existing dataset. This model can also transfer knowledge from a large set of integrated datasets to increase accuracy further.

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Method for scalable identification of spatially variable genes (SVGs) in spatially-resolved transcriptomics data. The method is based on nearest-neighbor Gaussian processes and uses the BRISC algorithm for model fitting and parameter estimation. Allows identification and ranking of SVGs with flexible length scales across a tissue slide or within spatial domains defined by covariates. Scales linearly with the number of spatial locations and can be applied to datasets containing thousands or more

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Spatially-aware quality control (QC) software for both spot-level and artifact-level QC in spot-based spatial transcripomics, such as 10x Visium. These methods calculate local (nearest-neighbors) mean and variance of standard QC metrics (library size, unique genes, and mitochondrial percentage) to identify outliers spot and large technical artifacts. Scales linearly with the number of spots and is designed to be used with 'SpatialExperiment' objects.

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omicsViewer visualizes ExpressionSet (or SummarizedExperiment) in an interactive way. The omicsViewer has a separate back- and front-end. In the back-end, users need to prepare an ExpressionSet that contains all the necessary information for the downstream data interpretation. Some extra requirements on the headers of phenotype data or feature data are imposed so that the provided information can be clearly recognized by the front-end, at the same time, keep a minimum modification on the existin

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The scDblFinder package gathers various methods for the detection and handling of doublets/multiplets in single-cell sequencing data (i.e. multiple cells captured within the same droplet or reaction volume). It includes methods formerly fou

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