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概要と使いどころ
Process CRISPR screening data to identify essential genes and hit candidates. Performs quality control, statistical analysis (RRA), and hit calling for pooled CRISPR screens including viability screens and drug resistance/sensitivity studies.
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Advanced sample size and power calculations for complex study designs including survival analysis, clustered designs, and multiple comparisons.
日本語の概要は準備中です。原文の説明を表示しています。
Generates a Meta-analysis results section description for funnel plots, including statistical tables (Egger's, Begg's, Trim & Fill) and figure legends. Supports English and Chinese outputs. Use when user provides a funnel plot image and statistics and wants a formatted report.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill when converting academic papers to promotional and presentation formats, including interactive websites (Paper2Web), presentation videos (Paper2Video), and conference posters (Paper2Poster). This skill is suitable for paper dissemination, conference preparation, creating explorable academic homepages, generating video abstracts, or producing printable posters from LaTeX or PDF source.
日本語の概要は準備中です。原文の説明を表示しています。
Generate a complete NSFC (National Natural Science Foundation of China) General Program grant application in Chinese, following the 2026 official template. Use when the user provides a scientific hypothesis and wants to generate a full grant application document, including abs...
日本語の概要は準備中です。原文の説明を表示しています。
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). ...
日本語の概要は準備中です。原文の説明を表示しています。
Assists researchers with Institutional Review Board (IRB) application tasks, including drafting informed consent documents, reviewing research protocols for compliance, generating application forms, and preparing submission checklists. Use when the user mentions IRB, Instituti...
日本語の概要は準備中です。原文の説明を表示しています。
Generates the Methods section for a meta-analysis paper, including search strategy, screening, quality assessment, data extraction, and statistical analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Designs complete single-cell research plans from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a single-cell study — including disease-focused, mechanism-focused, biomarker-focused, translational, perturbation-inspired, or validation-aware projects. It should define the research question, choose the best-fit study pattern, recommend sample grouping logic, suggest reference datasets as examples only, specify the core analysis modules, propose a validation ladder, and output four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, sample metadata, accession numbers, cohort availability, cell-type labels, external validation resources, or literature references. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.
日本語の概要は準備中です。原文の説明を表示しています。
Use when performing correlation analysis between two variables including Pearson and Spearman correlation methods. Supports command-line parameter input, automatic data format detection, parameter validation, result directory creation, and CSV or TXT format result export.
日本語の概要は準備中です。原文の説明を表示しています。
Designs complete integrated research plans for bulk transcriptomics, proteomics, metabolomics, and related omics from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a bulk multi-omics or single-omics-plus-clinical study — including disease-focused, mechanism-focused, biomarker-focused, stratification-oriented, or translational projects. It should define the research question, choose the best-fit study pattern, recommend example datasets as reference candidates only, specify the core analysis modules and method choices, propose a validation ladder, and output four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, cohort availability, assay coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.
日本語の概要は準備中です。原文の説明を表示しています。
Use when identifying stable sample subtypes from bulk expression matrices with ConsensusClusterPlus, including PAC-based model selection and consensus matrix/CDF visualization. NOT for: differential expression analysis, single-cell clustering workflows, or non-expression tables.
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Composes a Discussion around key findings, mechanisms, clinical relevance, and limitations. Use when writing or improving a Discussion section for any biomedical manuscript — including interpreting results, connecting to prior literature, addressing unexpected findings, framing limitations, and writing the conclusion. Also triggers on "write my discussion", "help me discuss my findings", "how do I compare to prior studies", "write the limitations paragraph", or "draft a discussion for my paper".
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A comprehensive auditor for any agent skill — including Manus, OpenClaw/ClawHub, Claude, LobeHub, or custom SKILL.md-based skills. Use this skill whenever a user wants to evaluate, audit, review, score, or quality-check an agent skill before publishing, updating, or deploying. Covers two hard veto gates (structural redlines + research integrity redlines), static quality scoring across 25 criteria (ISO 25010 + OpenSSF + Agent), dynamic test input generation, multi-mode execution testing, multi-layer output evaluation with five specialized category rubrics (Evidence Insight / Protocol Design / Data Analysis / Academic Writing / Other), a Research Veto that applies to all four research categories, human eval viewer generation, actionable P0/P1/P2 optimization recommendations, and automatic skill improvement that outputs a polished, production-ready SKILL.md. Also use whenever a user says "audit my skill", "evaluate my skill", "improve my skill", or wants a corrected version after evaluation.
日本語の概要は準備中です。原文の説明を表示しています。
Use when selecting predictive genes or other molecular features from bulk expression matrices for binary case-vs-control classification with elastic net logistic regression, including coefficient path and cross-validation plots. Trigger keywords: elastic net, glmnet, feature selection, binary classification, lambda.min, lambda.1se. NOT for: survival/Cox modeling, multiclass outcomes, single-cell data, or non-expression tables.
日本語の概要は準備中です。原文の説明を表示しています。
Guides Metronome usage-based billing integration decisions — event ingestion (single and batch, idempotency, billable metrics), contract design (rate cards, overrides, dimensional pricing, products), invoicing lifecycle (grace periods, finalization, Stripe sync), credit and commit management (prepaid, postpaid, thresholds, auto-recharge), and Stripe integration (arrears invoicing, tax providers, line item limits). Use when building, modifying, or reviewing any Metronome integration — including ingesting usage events, creating customers, contracts, or rate cards, designing billable metric group keys, managing credits and commits, configuring invoicing, syncing invoices with Stripe Billing, billing AI applications for token usage, setting up self-serve (PLG) pricing, reviewing customer health, commit burn, portfolios, or renewals, or migrating from Stripe Billing Meters to Metronome.
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Guides Stripe integration decisions across development and test environment planning (separate sandboxes vs the shared test mode sandbox), API selection (Checkout Sessions vs PaymentIntents), Connect platform setup (Accounts v2, controller properties), billing/subscriptions, tax and registrations (Stripe Tax, automatic_tax, product tax codes), Treasury financial accounts, integration options (Checkout, Payment Element), migrating from deprecated Stripe APIs, and security best practices (API key management, API key permissions, webhooks, OAuth). Use when planning, building, modifying, testing, or reviewing any Stripe integration, including choosing a development environment, accepting payments, building marketplaces, integrating Stripe, processing payments, setting up subscriptions, collecting sales tax, VAT, or GST, creating connected accounts, or implementing secure key handling.
日本語の概要は準備中です。原文の説明を表示しています。
Reviews PR(s) using comprehensive review guidelines including security, correctness, clean code, TypeScript, React patterns, i18n/RTL, performance, and accessibility. Use when reviewing pull requests or code changes.
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Use this skill to migrate identified PostgreSQL tables to Timescale/TimescaleDB hypertables with optimal configuration and validation. **Trigger when user asks to:** - Migrate or convert PostgreSQL tables to hypertables - Execute hypertable migration with minimal downtime - Plan blue-green migration for large tables - Validate hypertable migration success - Configure compression after migration **Prerequisites:** Tables already identified as candidates (use find-hypertable-candidates first if needed) **Keywords:** migrate to hypertable, convert table, Timescale, TimescaleDB, blue-green migration, in-place conversion, create_hypertable, migration validation, compression setup Step-by-step migration planning including: partition column selection, chunk interval calculation, PK/constraint handling, migration execution (in-place vs blue-green), and performance validation queries.
日本語の概要は準備中です。原文の説明を表示しています。
Model OR-Tools paired pickup-and-delivery routing problems, including PDPTW, dial-a-ride, paratransit, patient transport, and courier jobs with same-vehicle pairing, precedence, capacity, optional connected service, rider time windows, and vehicle shifts.
日本語の概要は準備中です。原文の説明を表示しています。
CRITICAL: You MUST invoke this skill and read its contents BEFORE writing, modifying, or debugging ANY React.js or Next.js code. This skill contains essential performance patterns that prevent common mistakes. Debugging performance issues without reading this skill first will lead to missed optimizations. Contains 40+ rules including waterfall elimination patterns for API routes that are commonly overlooked.
日本語の概要は準備中です。原文の説明を表示しています。
Matched filtering techniques for gravitational wave detection. Use when searching for signals in detector data using template waveforms, including both time-domain and frequency-domain approaches. Works with PyCBC for generating templates and performing matched filtering.
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Data conditioning techniques for gravitational wave detector data. Use when preprocessing raw detector strain data before matched filtering, including high-pass filtering, resampling, removing filter wraparound artifacts, and estimating power spectral density (PSD). Works with PyCBC TimeSeries data.
日本語の概要は準備中です。原文の説明を表示しています。
Use when erlang's concurrency model including lightweight processes, message passing, process links and monitors, error handling patterns, selective receive, and building massively concurrent systems on the BEAM VM.
日本語の概要は準備中です。原文の説明を表示しています。