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R generic interface to Hi-C contact matrices in `.(m)cool`, `.hic` or HiC-Pro derived formats, as well as other Hi-C processed file formats. Contact matrices can be partially parsed using a random access method, allowing a memory-efficient representation of Hi-C data in R. The `HiCExperiment` class stores the Hi-C contacts parsed from local contact matrix files. `HiCExperiment` instances can be further investigated in R using the `HiContacts` analysis package.

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Build prospect lists where the prospect is already one hop from the client, and write the line that says so. Seven members, each with its own source. Current-customer alumni is the priority member - everyone who ever worked at one of the client's customers or case-study companies and has since moved on. Triggers on "warm intro", "who do we know at that account", "they used to work at our customer", "alumni of our case study company", "shared investor angle", "who is in the same city as our rep", "did they visit our site". Outputs warm_intro_line plus a per-member evidence column.

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Evaluate and plan Amazon marketplace expansion across countries and regions. Use when a seller asks which Amazon marketplace to enter, how to compare international demand and economics, what tax, product-compliance, logistics, localization, account, or launch workstreams to investigate, or how to build a gated global-selling roadmap. Do not use as legal, tax, customs, or certification advice.

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Four-phase debugging framework that ensures root cause investigation before attempting fixes. Never jump to solutions.

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Use multiple Claude agents to investigate and fix independent problems concurrently

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Define a brand's target audience with deep personas, psychographics, and ICP (Ideal Customer Profile). Use when the user says "target audience", "ideal customer", "customer persona", "audience persona", "ICP", "who is our customer", "define our audience", "audience research", "buyer persona", "who should we be targeting", "audience profile", "customer profile", "who buys this", or needs to understand their audience more deeply before investing in brand or marketing work.

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Assess the health and consistency of an existing brand — identity, messaging, voice, positioning, and market perception. Use when the user says "brand audit", "brand review", "assess our brand", "is our brand consistent", "brand health check", "brand analysis", "something's off with our brand", "our brand feels outdated", "brand diagnosis", "review our brand", "brand gap analysis", or wants to understand where their brand is strong and where it needs work before investing in brand development.

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Define KPIs, metrics, and tracking systems to measure brand health, awareness, perception, and equity over time. Use when the user says "brand measurement", "brand metrics", "how do we measure the brand", "brand KPIs", "brand health tracking", "brand awareness metrics", "brand equity measurement", "is our brand working", "brand ROI", "brand performance", "brand tracking", "brand health score", "prove brand value", "brand dashboard", or needs to show stakeholders whether brand investment is delivering results.

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Your business planner. Compiles everything the other founder skills wrote (the board's verdict, the competitors, the buyer panel, pricing, the offer, the CFO's numbers, marketing, brand, operations and the launch plan) into one business plan with a verdict at the top that is computed from the numbers, never written by hand: Profitable, Not yet (with the failing numbers) or Incomplete. Adds an executive summary and a one-page version for a partner, lender or investor. Use when the user says "write my business plan", "put it all together", "is it profitable", "give me the plan", or at the end of the founder pack.

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Use the official Sentry CLI to investigate issues, events, traces, and logs for Vibe Remote without committing Sentry credentials into the repository.

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Use for authorized digital forensics including memory dumps, disk timelines, PCAP investigation, artifact triage, and IR evidence preservation.

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Use when you want phase research without planning: to investigate before deciding a phase is feasible, or to re-research after a plan already exists. Standalone command; most workflows should use /gsd-plan-phase instead.

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Use when a bug, failing test, or unexpected behaviour needs investigation, especially across sessions or context resets. Isolates it in a debugger subagent with persistent .planning/debug state, unlike skills/systematic-debugging.

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Your finance brain trust and decision partner. Named personas across 7 cells: valuation/corporate finance, investing, accounting/FP&A, macro, fintech, behavioral, and capital markets/M&A/private. Markets/quant/derivatives are reserved for…

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Generate clinical trial protocols for medical devices or drugs. This skill should be used when users say "Create a clinical trial protocol", "Generate protocol for [device/drug]", "Help me design a clinical study", "Research similar trials for [intervention]", or when developing FDA submission documentation for investigational products.

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Gathers knowledge from web and files, cross-references across multiple sources, and produces cited research documents. Use when investigating technologies, patterns, or decisions that need evidence backing.

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Evidence collection methods, problem categorization, analysis techniques, and solution design patterns

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Cyber threat intelligence and OSINT analysis toolkit. Runs structured investigations and delivers analyst-grade intelligence products with sourced, trust-scored findings. Use for OSINT and CTI cases, digital-footprint and exposure review, domain/subdomain/DNS/certificate recon, web-infrastructure pivoting (favicon hashes, tracker IDs, TLS certs, phishing-kit fingerprinting, campaign clustering), username/email/phone enumeration, breach and infostealer-log triage, image forensics, geolocation, crypto-wallet and IBAN/bank-account tracing, darknet search, M365/Azure and SaaS tenant recon, China/Sinophone recon (ICP filings, PRC corporate registries, Baidu/FOFA/Quake/ZoomEye), vulnerability and ransomware lookup, threat modeling, PII redaction, and structured reporting. Commands include /case, /sweep, /query, /webpivot, /username, /phone, /email-deep, /breach-deep, /icp, /cn-corp, /iban, /stealer-log, /exposure, /threat-model, /report, /brief, /redact, /apikeys.

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Debug LangChain and LangGraph agents by fetching execution traces from LangSmith Studio. Use when debugging agent behavior, investigating errors, analyzing tool calls, checking memory operations, or examining agent performance. Automatically fetches recent traces and analyzes execution patterns. Requires langsmith-fetch CLI installed.

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Investigate questions using high-trust primary sources and traceable citations. Use when the user asks for research, current documentation or API facts, source verification, or evidence-backed comparison.

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Resolve an in-progress Git merge or rebase conflict while preserving the relevant intent of both sides. Use when conflict markers or an interrupted merge/rebase need investigation and resolution.

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Coordinate nontrivial work in the ctx repository when a task has independent investigation, implementation, or test lanes; compute-heavy checks; or repetitive changes suited to scripts or codemods. Use for decomposition and concurrency decisions, not simple edits or questions.

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Implements structured diagnostics, correlation and justified metrics or traces; not incident investigation or a mandatory telemetry platform.

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Investigate requirements via atomic AC decomposition, actor/permission matrices, and truth-table edge cases; enforce User Story standards (scope fences, platform tags, toggles). Use when writing/reviewing Stories or AC with multi-condition logic, feature toggles, or market variants (VN/MY/SG).

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