「soft」の検索結果

Build weighted gene co-expression networks to identify modules of co-regulated genes, relate them to phenotypes, and find hub genes using WGCNA, hdWGCNA, MEGENA, CEMiTool, and Gaussian graphical models. Covers signed-network choice, soft-threshold selection, module preservation, and the marginal-vs-partial-correlation distinction. Use when finding co-expression modules, identifying hub genes, relating gene networks to clinical or experimental traits, or building single-cell co-expression networks. For directed TF-target inference see scenic-regulons and grn-inference; for condition rewiring see differential-networks.

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Build local BLAST databases and run searches using NCBI BLAST+ command-line tools. Use when running >50 queries, building custom databases with -parse_seqids and -taxid, downloading prebuilt NCBI databases via update_blastdb.pl, choosing -task variants (megablast/dc-megablast/blastn/blastn-short), tuning soft/hard masking, scaling threads, or extracting hits with blastdbcmd. Encodes BLAST v5 vs v4 database format, taxonomy filtering, makeblastdb pitfalls.

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Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda scheduling, soft-core potentials, MBAR/BAR analysis, cycle-closure validation, and protocol-appropriate enhanced sampling. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.

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Maintain and extend existing SceneKit 3D scenes and visualizations. Use when working with SCNView, SCNScene, SCNNode scene graphs, SceneKit geometry/materials/lights/cameras, SCNAction animation, SCNPhysicsBody physics, SCNParticleSystem effects, .scn/.dae/.abc SceneKit assets, shader modifiers, or SwiftUI SceneView. SceneKit is soft-deprecated and in maintenance mode; route new apps, significant updates, USD/USDZ pipelines, and migration planning toward RealityKit.

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This skill should be used when writing, reviewing, or refactoring Python code. Covers code integration, idiomatic patterns, docstring formatting, anti-abstraction rules, and software engineering basics.

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Find and query PI assets using MATLAB's Industrial Communication Toolbox. Two paths: (1) direct PI tag lookup via piclient + tags when user provides a tag name or description (R2022a+), (2) Asset Framework navigation via afclient when user needs element/attribute hierarchy (R2026a+). Use when working with PI AF servers, PI Data Archive tags, asset hierarchies, element templates, attribute lookup, or historical data from OSIsoft PI systems.

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Build industrial-grade SCADA/HMI dashboards in MATLAB following industrial-HMI conventions (ISA-101-aligned): gray-field philosophy, alarms at source, write safeguards, fixed-range trends, drill-down layout. Produces a real App Designer app (.mlapp, or plain-text .m+.xml on R2026b+) by handing serialization to the matlab-build-app skill when available, and falls back to a programmatic .m app otherwise. Use when wrapping OPC UA / Modbus / MQTT / OSI PI / PI AF monitoring scripts into a live operator app, building plant overviews, designing operator dashboards, or any time a user asks for a "SCADA dashboard", "HMI", "plant dashboard", "operator screen", or "industrial monitoring app" in MATLAB. Trigger on: SCADA, HMI, industrial dashboard, plant overview, operator screen, uigauge, uilamp, alarm banner, gray-field, ISA-101, OPC UA dashboard, setpoint, write safeguards, alarm visualization, OSIsoft PI, AVEVA PI, PI Server, PI Data Archive, PI AF, PI Asset Framework, piclient, afclient.

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Generate, sign, and verify SBOMs and provenance attestations to secure the software supply chain. Use when implementing SLSA controls, artifact trust policies, or compliance evidence for releases.

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Detect, respond to, and prevent software supply chain attacks on package registries, container images, and CI/CD pipelines with lockfile auditing, provenance verification, and emergency response playbooks.

日本語の概要は準備中です。原文の説明を表示しています。

Manage and secure company devices with MDM solutions — enroll macOS, Windows, iOS, and Android devices, enforce security policies, and automate software deployment. Use when setting up device management for a growing team.

日本語の概要は準備中です。原文の説明を表示しています。

Build, test, and deploy applications using GitHub Actions workflows. Create CI/CD pipelines, configure runners, manage secrets, and automate software delivery. Use when working with GitHub repositories, automating builds, running tests, or deploying applications.

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Maintain IT asset inventory and configuration management database. Track hardware, software, and cloud resources. Use when managing IT assets.

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Plan, build and quality-check a premium short commercial for a real business (roofing, property, ecommerce, B2B software) using AI-generated footage, code-built motion (HTML/GSAP), selective Three.js and an independent-critic "Gauntlet" loop. Use when asked to make a launch-style / SaaS-style video, business ad, explainer, sample reel or pitch video, or to review and improve one. Encodes motion principles distilled from 28 professional launch films, a quality bar, audio rules and a business-offer playbook.

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Automatically invoke this skill whenever the user asks why a Fabric capacity is busy, throttled, at 90 or 100 percent, or what is consuming CUs; asks for current capacity utilization, carry forward or per-item CU usage; wants to query or repair the Microsoft Fabric Capacity Metrics app or its semantic model; or wants to start, pause or monitor a capacity from a script or status bar.

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When the user wants to add or optimize structured data (Schema.org, JSON-LD). Also use when the user mentions "schema," "structured data," "JSON-LD," "rich results," "rich snippets," "Google rich snippets," "featured snippet schema," "add schema to page," "missing structured data," "schema validation error," "Schema Markup Validator," "Google Rich Results Test," "FAQ schema," "Article schema," "Organization schema," "JobPosting," "HowTo," "Event," "SoftwareApplication," "BreadcrumbList," "WebSite," "Recipe," "Product," or "Dataset." For SERP feature types and zero-click patterns, use serp-features. For AI search visibility strategy (not markup), use generative-engine-optimization. For HowTo step sections (placement, copy, vs FAQ), use howto-section-generator.

日本語の概要は準備中です。原文の説明を表示しています。

Rebuild or restyle editable Microsoft Visio diagrams from reference images and existing .vsdx files, then export deliverables as .vsdx, PNG, SVG, PDF, or PPTX. Use when the user asks Codex to open Visio, recreate a diagram from a PNG/JPG/screenshot/reference image, match a scientific model figure, update colors/typography/layout in a .vsdx, calibrate panel coordinates to avoid shifted or overlapping submodules, or make publication/presentation outputs while preserving Visio native editable shapes rather than embedding the reference image as a flat picture.

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Use this skill when the user wants to enable, disable, turn on or off, opt out of, opt in to, or check the status of pcf telemetry or its usage data. Triggers: "disable telemetry", "turn off telemetry", "opt out of telemetry", "stop collecting usage data", "enable telemetry", "telemetry status".

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Use this skill when the user wants to "report a bug", "file an issue", "report an issue", "submit a bug report", or report any problem with the pcf plugin to the GitHub repository.

日本語の概要は準備中です。原文の説明を表示しています。

Adds or extends multilingual localization in a Power Pages code-site SPA. Use whenever the user asks to translate, localize, internationalize, support multiple languages, add a language selector, add locale routes, repair an i18n setup, or add languages to an existing React, Vue, Angular, or Astro Power Pages site.

日本語の概要は準備中です。原文の説明を表示しています。

Use when investigating slow activities, waiting, handoff duration, bottlenecks or cumulative activity workload.

日本語の概要は準備中です。原文の説明を表示しています。

Use when comparing process cohorts, departments, periods or before-and-after results under matched definitions.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a Process Mining overview, initial process selection, or an analytical follow-up needs routing.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a requested measure is missing, a saved custom metric needs reuse, or an ephemeral formula or derived scalar is needed.

日本語の概要は準備中です。原文の説明を表示しています。

Use when seeking explanatory attributes or hypotheses for differences in process duration, waiting, utilization or rework.

日本語の概要は準備中です。原文の説明を表示しています。