Explore possible next roles from a user's actual tasks, interests, and constraints, including adjacent roles and changes within their current workplace. Build evidence-linked career hypotheses, identify unknown duties and requirements, and propose small ways to test them. Use when someone does not know what work to pursue or asks what they could do beyond their current job; do not diagnose aptitude, rank careers, or predict salary or hiring success.
日本語の概要は準備中です。原文の説明を表示しています。
ficilcom/otame4-work-skills☆ 42026年9月23日 更新
Keep GPT-5.6 and other coding-agent work proportional to the request by locking scope, choosing the smallest sufficient implementation, matching verification to risk, and stopping when success is proven. Use for implementations, bug fixes, refactors, reviews, or maintenance where scope creep, speculative abstractions, unrelated cleanup, repeated test runs, unnecessary dependencies, or polishing beyond the request are risks.
日本語の概要は準備中です。原文の説明を表示しています。
Swallow100/gpt-5.6-stop-overengineering☆ 42026年8月5日 更新
Shakes your mental models with critical rigor, challenges assumptions, exposes blind spots, and provides multi-perspective insights as a strict thinking mentor. Deliberately breaks format conventions to stimulate genuine cognitive discomfort. Use when you want to stress-test an idea, shake your mental model, ask to challenge my assumptions, find blind spots, deepen my thinking, or request critical review with phrases like yusaburi or what do you think of this plan.
日本語の概要は準備中です。原文の説明を表示しています。
iepyon/pocket-modeling☆ 42026年9月6日 更新
社員が申請したソフトウェア・SaaS・クラウドサービスの社内利用可否を、企業のIT/セキュリティ統制の観点から調査・評価するスキル。「〇〇のセキュリティ評価をして」「〇〇は社内で使っても大丈夫?」「このSaaSのセキュリティチェックをして」「新しいツールの導入審査をして」「〇〇と△△どちらが安全?」のような依頼で必ず使うこと。「セキュリティ」という言葉がなくても、特定のツール・サービスの社内導入可否・利用申請・リスク判断が話題になったら使う。Web検索で一次情報(プライバシーポリシー、利用規約、セキュリティホワイトペーパー、第三者認証)を収集し、6分野18項目のチェックリストに基づく3段階リスク評価付きの日本語レポート(Markdownファイル)と、ワークフロー(稟議)システムの承認コメント欄に貼れる短文サマリーを生成する。
asaponi-corpeng/it-security-review☆ 42026年8月21日 更新
review-all を実行し、指摘内容をコードに反映、bun run c / bun run lint / bun test で自己検証し、CONVERGED/NOT_CONVERGED の収束判定付き完了レポートを /tmp/arima-review-fix-result.md に出力する。レビュー→修正→検証→レポートを一気通貫で行うスキル。スコープ引数は /review-all と同じ(wt / PR #N / vs:<branch> / range / ファイル列挙)。review-fix-loop からの自動呼び出し(mode=non-interactive)にも対応。Use when user says 'レビューして直して', 'review and fix', '自動修正', 'レビュー反映', or when invoked by review-fix-loop.
sogengineer/arima-analy☆ 42026年9月21日 更新
全 8 レビュースキル(arch/code/scoring/security/test/naming/recovery/comments)を並列実行し、統合レポートを出力するオーケストレーションスキル。レビュー範囲は引数で指定可能(wt=作業ツリー / PR #N / pr:N / vs:<branch> / git range / ファイル列挙、デフォルトは比較ブランチとの差分)。Use when user says '全レビュー実行', 'review all', '一括レビュー', '総合チェック', 'PR レビュー', or '<branch> との差分レビュー'.
sogengineer/arima-analy☆ 42026年9月21日 更新
外部データ取得と取り込み経路のセキュリティレビュー。JRA 以外のホストへ取りに行かせない URL 検証(SSRF)、スクレイピングの作法(User-Agent・リクエスト間隔・タイムアウト)、外部由来 HTML/JSON を無検証で DB に入れない、クエリを Kysely で組み立て生の SQL 文字列を増やさないこと、CLI 由来のファイルパスの扱い、生成物(*.db / data/extracted-*.json / data/jra-page.html)と .env をコミットさせないことを検証。Use when user says 'セキュリティレビュー', 'review security', 'セキュリティチェック', 'SSRF確認', or 'SQLインジェクション確認'.
sogengineer/arima-analy☆ 42026年9月21日 更新
Audit a browser fingerprint for internal contradictions with the liarjs CLI - canvas, WebGL, WebGL2, WebGPU, audio, 220 fonts, WebRTC and timezone probes, scored against the TLS/HTTP/ASN view of the same request. Use when asked to run a browser fingerprint test, see what a fingerprint looks like, check canvas or WebGL fingerprint stability, compare a spoofed profile against a real browser, or find out whether a browser profile is self-consistent.
日本語の概要は準備中です。原文の説明を表示しています。
liarjsdev/liarjs-skills☆ 42026年8月6日 更新
Check whether a Playwright, Puppeteer, Selenium or CDP-driven browser presents a coherent fingerprint, using liarjs as a library against a Page you already have - navigator.webdriver, HeadlessChrome tokens, worker versus main-thread identity, patched-API integrity, WebGL versus WebGPU GPU identity. Use when asked whether an automated browser looks like a normal one, when a headless setup or a stealth plugin's effect needs measuring rather than assuming, or when an assertion on fingerprint quality belongs in a test suite.
日本語の概要は準備中です。原文の説明を表示しています。
liarjsdev/liarjs-skills☆ 42026年8月6日 更新
Add or modify a Flask endpoint in the Lyrion Dashboard. Use this whenever a task adds a new URL/route, a JSON API endpoint, or a page — anything that registers a handler in `routes/`. Covers the repo's route → service → test layering, input validation, caching headers, security headers, i18n wiring, and the exact test pattern, so a new endpoint matches how `routes/` already works instead of reinventing the structure.
日本語の概要は準備中です。原文の説明を表示しています。
werdeil/lyrion-dashboard☆ 32026年10月15日 更新
Write or fix a test in the Lyrion Dashboard's suite. Use this whenever a task adds a test, changes one, or asks why the suite fails — anything touching `tests/`. Covers the standalone-per-file scaffolding, the env-before-import rule, where to patch (the route/service the code under test imports), the cache-and-clock testing pattern, and how to run one test vs the whole suite. Reach for it any time you touch `tests/` so new tests match the existing shape instead of re-inventing setup.
日本語の概要は準備中です。原文の説明を表示しています。
werdeil/lyrion-dashboard☆ 32026年10月15日 更新
Analyze spatial cell-cell interactions, neighborhoods, and niches in IMC/MIBI data with squidpy and imcRtools, covering neighborhood-enrichment permutation nulls, the abundance-vs-density confound, inhomogeneous Ripley's K, cellular-neighborhood discovery, graph-construction (contact vs proximity), and edge effects. Use when testing whether cell types co-locate, choosing a spatial null, building a neighbor graph, discovering tissue niches, or deciding whether a spatial pattern is real or a density/segmentation artifact.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Tests whether two genomic interval sets overlap (colocalize) more than expected by chance using a permutation test against a structured-genome null model. Covers bedtools fisher (analytic 2x2 screen), bedtools shuffle + jaccard permutation, GAT (isochore/GC-conditioned simulation with FDR), regioneR (flexible permutation, randomizeRegions vs circularRandomizeRegions, localZScore), LOLA (universe-relative Fisher against a region database), and GREAT/rGREAT (regulatory-domain binomial + hypergeometric for ontology-from-regions). Stresses the universe/background choice, matched background, blacklist exclusion, and multiple-testing control. Use when asking whether peaks/regions are enriched at enhancers/TFBS/features, scoring region-set colocalization or region-set enrichment, comparing CNV/SV concordance, or turning an overlap count into a defensible p-value.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Compare cell-type composition and spatial features across conditions in IMC/MIBI cohorts with the patient as the experimental unit, covering pseudoreplication, per-patient aggregation, mixed models, compositional (Dirichlet/scCODA) differential abundance, diffcyt, per-image-to-patient spatial differential testing (SpaceANOVA), batch covariates, and FDR. Use when testing whether a cell type or spatial niche differs between groups, avoiding cell-level pseudoreplication, choosing a differential-abundance method, or correctly powering an IMC cohort comparison.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Compares Hi-C contact maps between conditions across the right scale -- differential bin-pair contacts (multiHiCcompare, diffHic), differential A/B compartments (dcHiC), differential TAD boundaries (delta insulation), and differential loops (diffloop, DiffHiChIP) -- with distance-stratified between-sample normalization, replicate-aware NB-GLM FDR, HiCRep SCC reproducibility gating, and CNV correction for cancer/aneuploid samples. Use when comparing Hi-C between treatment and control, finding differential contacts/compartments/boundaries/loops, normalizing two maps of unequal depth, choosing a replicate-aware test, gating replicates with SCC, or correcting copy-number artifacts before a tumor-vs-normal comparison.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Performs set operations on genomic intervals - intersect (-wa/-wb/-wo/-wao/-loj/-c/-v/-u), subtract (-A), merge (-d, -c/-o), complement, cluster, multiinter, unionbedg, map, and groupby - with bedtools (CLI) and pybedtools/pyranges/bioframe (Python). Covers the sorted-input contract and the -sorted chromosome-order footgun, reciprocal/fractional overlap (-f/-F/-r/-e) and the A-vs-B asymmetry, -split for spliced/BED12/BAM features, and jaccard/fisher as mechanics only. Use when finding overlapping or unique regions between BED/peak/feature files, building consensus peaksets, removing blacklisted regions, transferring annotation values onto intervals, or computing interval-set similarity; route overlap-significance testing to overlap-significance.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Extracts, filters, annotates, and exports differential expression results from DESeq2 or edgeR with proper handling of padj=NA (independent filtering, Cook's outliers, all-zero), multiple-testing correction choice (BH vs Storey q-value vs IHW vs lfsr), TREAT vs post-hoc fold-change filtering, p-value histogram diagnostics, gene annotation via org.db/biomaRt/mygene, GSEA preranked input, ORA background construction, replication reality (Schurch 2016 small-n result), and SABV/sex-stratified reporting. Use when extracting and interpreting DE results, troubleshooting padj=NA, choosing FDR method, preparing ranked lists for pathway analysis, annotating gene IDs, or comparing DESeq2 vs edgeR outputs.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Differential abundance (DA) and differential state (DS) analysis for flow and mass cytometry - tests which cell populations change in frequency or marker expression between conditions using diffcyt (edgeR/voom/GLMM for DA, limma/LMM for DS), with cydar, CITRUS, and compositional methods (sccomp, scCODA, DCATS) as alternatives. Covers the sample-is-the-experimental-unit principle, design/contrast and mixed-model formulas, compositionality of cluster proportions, and FDR across clusters. Use when comparing populations between groups, choosing a DA method, handling paired/batch designs, or deciding whether compositional correction is needed.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Delimits putative species boundaries from molecular data within the de Queiroz 2007 unified-lineage framework using ASAP (Puillandre 2021 successor to ABGD), mPTP C++ (Kapli 2017 successor to bPTP; bPTP is Python NOT R), GMYC single/multi-threshold (Pons 2006; Fujisawa 2013), multilocus BPP v4 with prior calibration from data (NOT defaults; Yang 2015), SNAPP + BFD* for SNP delimitation, DELINEATE (Sukumaran 2021) speciation-process modeling to address Sukumaran & Knowles 2017 PNAS critique that MSC delimits structure not species, integrative-taxonomy congruence (Padial 2010; Carstens 2013), Dsuite for introgression testing before sister claims (Malinsky 2021), and Meyer & Paulay 2005 barcoding-gap-absence caveat. Use when delineating species from DNA barcoding data, resolving cryptic complexes, choosing among ASAP/mPTP/BPP/DELINEATE, calibrating BPP priors, distinguishing introgression from ILS, or applying the Sukumaran-Knowles oversplitting correction.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Identifies differential m6A methylation between conditions from MeRIP-seq paired IP/input data using exomePeak2 with `bam_ip` + `bam_input` (control arm) and `bam_treated_ip` + `bam_treated_input` (treatment arm) for integrated GC-bias-aware differential calling (Liu 2022 *NAR Genom Bioinform* 4:lqac046), QNB beta-binomial test (Liu 2017 *BMC Bioinformatics* 18:387), MeTDiff HMM-based differential bundled with MeTPeak, RADAR (Zhang 2019 *Genome Biol* 20:294) with its `filterBins -> diffIP -> reportResult` workflow, and the defensible paired-symmetric case of edgeR / DESeq2 on featureCounts-on-peaks matrices when batch / lot covariates need explicit fixed-effect handling (exomePeak2's top-level API does NOT accept arbitrary covariates). Covers paired vs unpaired vs interaction designs, batch confounding (antibody lot, RNA prep, sequencing run) and the per-lot meta-analysis strategy when exomePeak2 is the primary caller, the stoichiometry-vs-expression-vs-IP-efficiency confound that all MeRIP differential methods inherit, normalisation choice (size factor on IP, on input, on per-sample IP/input ratio), the McIntyre 2020 reproducibility caveat, effect-size filtering as a guardrail against under-powered N=2 designs, and orthogonal-validation routes for absolute stoichiometry (GLORI / SAC-seq / m6Anet `mod_ratio`). Use when comparing m6A levels across two or more conditions, choosing between exomePeak2 / QNB / RADAR / MeTDiff for a given design, handling batch confounding when exomePeak2's API is too rigid, normalising against input properly, distinguishing real hyper- / hypo-methylation from expression-level shifts, applying effect-size thresholds, interpreting volcano plots of differential peaks, or planning a follow-up orthogonal stoichiometry validation.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Analyzes species-environment relationships with constrained ordination (CCA, RDA, db-RDA), variance partitioning, indicator species (indicspecies IndVal.g group-equalized), PERMANOVA paired MANDATORILY with PERMDISP (Anderson & Walsh 2013; dispersion confounds centroid tests), Joint Species Distribution Models (HMSC, sjSDM, gjam) with explicit rejection of "residual covariance equals biotic interaction", phylogenetic community ecology (SES_MPD/MNTD), trait-environment via RLQ + fourth-corner with corrected modeltype=6 (Dray 2014), bipartite network metrics (NODF, modularity) with curveball null (Strona 2014), and Mantel-test replacements (dbRDA, GDM) for spatial data. Use when testing how environmental gradients structure communities, identifying habitat indicator taxa, partitioning variance among predictors, deciding whether PERMANOVA significance is location vs dispersion, picking among HMSC/sjSDM/gjam, or replacing Mantel tests for landscape data.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新
Performs differential expression on bulk RNA-seq count data with DESeq2's negative-binomial GLM, Wald and LRT testing, apeglm/ashr/normal LFC shrinkage, independent filtering, Cook's outlier handling, VST/rlog transforms, and design formulas including paired, batch, and interaction terms. Use when running bulk DE, choosing DESeq2 over edgeR or limma-voom, building a paired or interaction design, applying LFC shrinkage for ranking or GSEA, choosing Wald vs LRT, troubleshooting padj=NA, picking VST vs rlog, importing salmon/kallisto via tximport, or analyzing prokaryotic RNA-seq.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月13日 更新