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概要と使いどころ
Query the STRING database for protein-protein interactions (PPIs), functional enrichment, and homology. Use when the user asks about interactions between specific proteins, interaction evidence, confidence scores, protein interaction partners, or pathway enrichments.
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Teaches evidence-based analysis of transaction logs and traces. Use when reconstructing transaction behavior from tables, TSV/CSV files, timestamps, counters, object histories, validation records, abort records, retries, partial logs, or when producing classified transaction outputs from trace evidence.
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dontbesilent 执行力诊断。用阿德勒心理学框架诊断你「知道该做什么但就是不做」的真正原因。 触发方式：/dbs-action、/action、「我知道该怎么做但就是不做」「为什么我总是拖延」 Execution block diagnosis using Adlerian psychology framework. Trigger: /dbs-action, "I know what to do but can't do it", "why do I procrastinate"
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Generates several distinct, clickable HTML interaction prototypes for one product surface into a Design Board and collects selection/remix feedback before implementation. Use for multiple UI versions, interaction alternatives, progressive-disclosure options, or when styling is fine but hierarchy/workflow/interaction feels off. Not for static visual-style calibration (use design-style-picker) or a settled CSS tweak.
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Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Nat Commun 12:1302), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.
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Analyze any OFAC or OFSI enforcement action — by URL, pasted text, or uploaded document — and produce a structured root cause analysis as a formatted Excel (.xlsx) spreadsheet. Use this skill whenever a user names, links to, pastes, or uploads an OFAC or OFSI enforcement action and asks for any of the following: root cause analysis, compliance gaps, what went wrong, lessons learned, organizational self-assessment, or remediation planning. Also trigger when a user asks "analyze this enforcement action", "what were the root causes", "turn this into a checklist", or "how do I make sure this doesn't happen to us". Outputs a single-sheet .xlsx table with six columns: Root Cause | What Went Wrong | How It Went Wrong | What Could Have Stopped It | Is my organization immune to this? (Yes/No/Partial) | Notes.
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Analyze the photograph uploaded by the user, deconstruct its visual evidence, abstract and distill the essential relationships, then reconstruct them as a new nonliteral lower-panel composition guided by 19 bundled references. Use for CLEAN upper-photo/lower-abstraction editorial artworks with a number, date, and short phrase in the lower panel. This is abstraction and reconstruction, never style conversion or a miniature redraw. Preserve the exact user-uploaded photograph unchanged above.
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Applies the Bullseye Framework from Traction by Gabriel Weinberg and Justin Mares. Use when choosing growth channels, testing customer acquisition strategies, or deciding where to spend marketing effort. Covers all 19 traction channels with selection methodology, testing protocol, and phase-matched channel advice. Triggers include 'how do we get customers', 'which marketing channel should we use', 'we have a product but no users', 'our growth has stalled', 'should we do content marketing or paid ads', 'how do we test traction channels', 'what channels work at our stage'. NOT for product development (use Lean Startup), not for positioning/messaging (use Obviously Awesome), not for pricing (use Monetizing Innovation), not for enterprise sales methodology (use SPIN Selling).
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Upload video/audio media to BytePlus VOD (Video on Demand) storage, returning the Vid and playback references; supports local file upload (ApplyUploadInfo + TOS + CommitUploadInfo) and URL pull upload (UploadMediaByUrl); also submits frame extraction jobs on ingested media (StartExecution / Operation.Task.Snapshot), including specified time, fixed interval, specified frame, scene-change, sprite image, and output index modes. Trigger keywords: VOD frame extraction, frame extraction, extract frames, video snapshot, thumbnail, screenshot from video, StartExecution Snapshot.
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Use when you need programmatic JDBC in Micronaut — pooled DataSource, parameterized SQL, io.micronaut.transaction.annotation.Transactional, batching, and domain exception translation. This should trigger for requests such as Review JDBC or SQL data access in a Micronaut project; Improve transactions and parameter binding for Micronaut JDBC; Translate SQLException to domain exceptions or stream large result sets; Fix self-invocation bypassing @Transactional in Micronaut; Review Hikari or pooled datasource usage in Micronaut JDBC. Part of Plinth Toolkit
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Read, write, and edit ChemDraw CDX/CDXML files with RDKit's rdkit.Chem.rdChemDraw plus direct XML editing, always paired with a rendered PNG. Parse molecules and reactions from .cdxml/.cdx, write structures with good 2D depiction, and hand-build or modify the parts RDKit cannot write: reaction arrows, plus signs, schemes/steps, and text/labels. Use for reaction schemes, synthesis routes, mechanisms, retrosynthesis, or SI figures. Critical: RDKit writes structures only — round-tripping a reaction through a Mol silently drops arrows and text; this skill shows the XML layer that preserves them. For pure molecular analysis (descriptors, fingerprints, SMARTS) use rdkit-cheminformatics; for multi-format 3D conversion use openbabel.
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NEB-IRC activation energy pipeline for reaction barriers using GFN2-xTB and pysisyphus. Optimize reactant and product geometries, run CI-NEB path search, optimize the transition state with a Hessian, verify with IRC (one imaginary mode, endpoints matching reactant/product, single NEB maximum), and report the electronic and Gibbs barriers. Use when you need a transition state, reaction barrier, activation energy, minimum energy path, or intrinsic reaction coordinate. Covers reactant/product atom-ordering pitfalls, feasibility sizing for single-core runs, and thermochemistry corrections. Renders an IRC energy-profile plot and an animated TS imaginary-mode HTML viewer. For 2D reaction scheme drawing use rdkit-chemdraw-cdxml.
日本語の概要は準備中です。原文の説明を表示しています。
Unified content extraction and action planning. Use when user says "tapestry <URL>", "weave <URL>", "help me plan <URL>", "extract and plan <URL>", "make this actionable <URL>", or similar phrases indicating they want to extract content and create an action plan. Automatically detects content type (YouTube video, article, PDF) and processes accordingly.
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Creates intuitive user experiences through feedback patterns, microinteractions, and accessible interaction design. Use when designing loading states, error handling UX, animation guidelines, or touch interactions.
日本語の概要は準備中です。原文の説明を表示しています。
Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Cell Reports 36:109597), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.
日本語の概要は準備中です。原文の説明を表示しています。
CesiumJS interaction and picking - ScreenSpaceEventHandler, multi-key KeyboardEventModifier input actions, Scene.pick, Scene.drillPick, Scene.pickPosition, Scene.snap edge snapping (1.144), mouse and touch events. Use when handling user clicks on the globe, selecting entities or 3D Tiles features, registering modifier-key shortcuts, implementing hover effects, snapping to model edges for measurement, or building drag-based interactions.
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Expert in designing and implementing visceral, satisfying combat systems. Masters hitbox/hurtbox design, frame data, combo systems, enemy archetypes, damage feedback, and the invisible craft that makes players feel powerful. Draws from fighting games, character action games (DMC, Bayonetta), and Souls-like design to create combat that is readable, responsive, and endlessly replayable. Use when "combat system, combat design, hitbox, hurtbox, frame data, hitstop, screen shake, input buffer, coyote time, i-frames, invincibility frames, combo system, attack cancel, recovery frames, punishment window, souls-like combat, action game combat, fighting game, damage feedback, enemy design, boss design, attack telegraph, parry system, stamina system, poise system, weapon feel, game feel combat, melee combat, combat juice, combat, action-game, fighting-game, hitbox, frame-data, game-feel, souls-like, character-action, melee, enemy-design, boss-design, combo, parry, i-frames" mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive expertise in ERC-4337 account abstraction, smart contract wallets, paymasters, bundlers, and user operation handling. Covers social recovery, session keys, gas sponsorship, and wallet SDKs. Use when "account abstraction, ERC-4337, smart wallet, paymaster, bundler, user operation, gasless transaction, session keys, social recovery, smart account, " mentioned.
日本語の概要は準備中です。原文の説明を表示しています。
Act as a project-management copilot (PM/PMO) for the delivery loop: charters, plans and schedules, estimates, risk registers, status reports, scope changes, stakeholder communication, meeting actions, lessons learned, and portfolio roll-ups, in a per-project `_project/` workspace. Use whenever the user wants to start, plan, track, rescue, or report on a project: "kick off this project", "make a project plan / timeline / WBS", "what date can I commit to", "build a risk register", "run a pre-mortem", "write the weekly status report", "the deadline slipped, what now", "turn this meeting into action items", "review my project portfolio", in any language ("quản lý dự án", "gestion de projet", "プロジェクト管理", "项目管理"), even when they never say "project management". Also use whenever a `_project/` directory exists and the user asks about schedule, deadline, risk, status, scope, budget, or stakeholders. Not for what to build (product-manager) or company-level bets (strategy-board).
Manage pinned tags and commit SHAs for GitHub Actions security, resolving mutable tags to immutable commit references. Use when the task involves `Unpinned tag for a non-immutable Action`, `pin GitHub Action to commit SHA`, `resolve git tag to SHA`, or `GitHub Actions security hardening`.
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Comprehensive guide for building robust, secure, and efficient CI/CD pipelines using GitHub Actions. Use when the task involves `creating or editing GitHub Actions workflows`, `.github/workflows/*.yml`, `CI/CD pipelines`, `GitHub Actions best practices`, or `workflow optimization`.
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Audits GitHub Actions workflows for security vulnerabilities in AI agent integrations including Claude Code Action, Gemini CLI, OpenAI Codex, and GitHub AI Inference. Detects attack vectors where attacker-controlled input reaches AI agents running in CI/CD pipelines, including env var intermediary patterns, direct expression injection, dangerous sandbox configurations, and wildcard user allowlists. Use when reviewing workflow files that invoke AI coding agents, auditing CI/CD pipeline security for prompt injection risks, or evaluating agentic action configurations.
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Enforce mandatory pre-action verification checkpoints to prevent pattern-matching from overriding explicit reasoning. Use this skill when about to execute implementation actions (Bash, Write, Edit) to verify hypothesis-action alignment. Blocks execution when hypothesis unverified or action targets different system than hypothesis identified. Critical for preventing cognitive dissonance where correct diagnosis leads to wrong implementation.
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[AUTO-INVOKE] MUST be invoked when debugging failed on-chain transactions. Covers transaction receipt analysis, gas diagnosis, calldata decoding, revert reason extraction, and state verification. Trigger: any task involving failed tx analysis, revert debugging, or on-chain transaction troubleshooting.
日本語の概要は準備中です。原文の説明を表示しています。