「cro」の検索結果

Detect syntenic blocks and structural rearrangements between genomes using MCScanX (Wang 2012), JCVI/MCScan (Tang 2008 Python), GENESPACE (Lovell 2022) for orthology-anchored riparian visualization, SyRI for structural variation, AnchorWave for sequence-level synteny, i-ADHoRe 3.0 for highly diverged species, SynNet for synteny networks, and ntSynt for multi-genome macrosynteny. Use when identifying collinear gene blocks across species, distinguishing macrosynteny from microsynteny, detecting inversions/translocations/duplications, anchoring orthology in WGD lineages, producing publication riparian plots, computing synteny block age via Ks (cross-references whole-genome-duplication), or running synteny-aware ortholog inference in polyploids.

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When you want to set up an agent loop, cron-scheduled task, or recurring workflow that runs autonomously. Judgment layer on top of Claude Code's ScheduleWakeup, CronCreate, and /loop — or, on other hosts, cron/GitHub Actions plus a headless agent CLI. Picks dynamic pacing, fixed cron, or a one-shot loop; designs idempotent loop bodies; sets bail-out conditions so loops don't run forever. Examples — weekly review pulse, daily brief, hourly metric monitor, periodic vault compile, upstream-check for an adapted skill. Triggers on "/loopify," "set up a loop," "schedule this task," "run this daily," "run this weekly," "cron this," "make this recurring," "automate this on a schedule," "keep this running until X." Part of the -ify trifecta (skillify / toolify / loopify). NOT for authoring a new skill — that's skillify. NOT for adding a tool/integration — that's toolify.

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Guidance for implementing CollectionView in .NET MAUI apps — data display, layouts (list & grid), selection, grouping, scrolling, empty views, templates, incremental loading, swipe actions, and pull-to-refresh. USE FOR: "CollectionView", "list view", "grid layout", "data template", "item template", "grouping", "pull to refresh", "incremental loading", "swipe actions", "empty view", "selection mode", "scroll to item", displaying scrollable data, replacing ListView. DO NOT USE FOR: simple static layouts without scrollable data (use Grid or StackLayout), map pin lists (use Microsoft.Maui.Controls.Maps), table-based data entry forms, non-MAUI list controls, CarouselView or BindableLayout questions, platform-specific handler or renderer customization, diagnosing CollectionView bugs in the MAUI framework itself, or general MVVM/binding questions that merely happen to mention a list (use maui-data-binding).

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Use when you need to implement or improve Java metrics observability with Micrometer — including meter design, naming/tag conventions, cardinality control, timers/counters/gauges/distribution summaries, percentiles/histograms, Actuator/Prometheus integration, and metrics validation through tests. This should trigger for requests such as Improve metrics; Apply Micrometer; Add metrics observability; Refactor Micrometer instrumentation; Add Micrometer timers counters or gauges to Java services. Part of Plinth Toolkit

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Use when managing multiple initiatives across time horizons (now/next/later, H1/H2/H3), balancing risk vs return across portfolio, sizing and sequencing bets with dependencies, setting exit/scale criteria for experiments, allocating resources across innovation types (core/adjacent/transformational), or when user mentions portfolio planning, roadmap horizons, betting framework, initiative prioritization, innovation portfolio, or resource allocation across horizons.

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Harmonises data classification across jurisdictions mapping GDPR special categories vs CCPA sensitive PI (1798.140(ae)) vs HIPAA PHI (160.103) vs LGPD sensitive data (Art. 5-II). Provides cross-regulation mapping matrix for multinational compliance. Keywords: cross-jurisdiction, GDPR, CCPA, HIPAA, LGPD, sensitive data, multinational, classification mapping.

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Fix Flutter PageView "snap back" or scroll position reset issues on provider/state rebuilds. Use when: (1) PageView scrolls then snaps back to previous page after state update, (2) Scroll position resets when Riverpod/Provider rebuilds, (3) Feed scrolls back to top on data refresh, (4) PageView loses position after orientation change or widget rebuild.

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Macro regime analysis, bull bear market detection, business cycle analysis, macro environment assessment, interest rate cycle, yield curve analysis, monetary policy, fiscal policy, global macro, central bank posture, credit cycle, recession probability, expansion regime, macro regime shift, stagflation detection

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Comprehensive expertise in cross-chain infrastructure, including LayerZero, Wormhole, Axelar, and custom bridge implementations. Covers omnichain token standards, message passing, bridge security, and cross-chain application architecture. Use when "cross-chain, bridge, LayerZero, Wormhole, Axelar, omnichain, multi-chain, chain abstraction, cross-chain messaging, token bridge, " mentioned.

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Detects attacks from server logs and blocks malicious IPs with CrowdSec, an open-source, crowd-sourced alternative to fail2ban. Use when a user asks to block brute force attempts, protect SSH or a web server, set up a community blocklist firewall, add a WAF, or install CrowdSec with Docker.

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Microsoft Advertising (Bing Ads) platform expertise. Audit campaigns, keywords, audiences, and UET tracking. Use when the user asks about Microsoft Ads, Bing Ads, search advertising on Microsoft, LinkedIn audience targeting, or Performance Max campaigns on Microsoft.

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临床诊断思维 (临床诊断思维 / 临床推理 (Clinical Diagnostic Reasoning) — 医生『怎么想病』的元学科:从症状/体征/检查到诊断结论的认知操作系统,从业者(临床医生/住院医/规培生,尤其全科/急诊/大内科等以未分化主诉为生的科室)、医学生与医学教育者、诊断安全与质量改进研究者、以及做医疗 AI 辅助诊断产品的人的视角。覆盖: (a) 第一性张力 — **直觉模式识别 (System 1: illness scripts 疾病脚本 / pattern recognition / gestalt, 『资深人一眼认出 aunt Minnie』) ⇄ 分析性推理 (System 2: hypothetico-deductive 假设演绎 / Bayesian 概率更新)** 的 dual-process 双过程理论 (Kahneman→Croskerry/Norman 谱系), 资深≠更会分析而是『脚本库更大+校准更好』; 更深层论战 — **『认知去偏可教 (Croskerry: bias awareness / cognitive forcing strategies / diagnostic timeout) ⇄ 偏倚标签是马后炮、知识结构才是主因 (Norman/Sherbino/Monteiro: debiasing 干预 transfer 证据弱, bias 是 hindsight 标签)』** — 本行最核心学术对垒; 『概率思维 (验前概率 × 似然比 → 验后概率, Pauker-Kassirer test/treatment threshold 阈值模型) ⇄ 穷尽式排查 (rule-out everything / 防御性医疗 / VOMIT)』; 『临床 gestalt ⇄ 结构化临床决策规则 (Wells/PERC/HEART)』; 『诊断简约 Occam's razor ⇄ Hickam's dictum (病人可以同时得 N 个病)』; 『床旁体格检查复兴 (Verghese Stanford 25 / McGee 循证体检) ⇄ 影像检验替代床旁』; (b) 方法论正典 — illness script theory (Schmidt/Boshuizen: enabling conditions/fault/consequences 三段结构), problem representation + semantic qualifiers 问题表征与语义限定词 (Bowen NEJM 2006, 把病人翻成 one-liner), hypothetico-deductive model (Elstein 1978《Medical Problem Solving》: 早期假设生成+定向检验), Bayesian 工具箱 (sensitivity/specificity/LR/Fagan nomogram/SnNout-SpPin), threshold model (Pauker-Kassirer NEJM 1975/1980), 认知偏倚分类学 (anchoring/premature closure/availability/confirmation/base-rate neglect/search satisficing/diagnostic momentum — Croskerry 偏倚清单), 去偏与元认知策略 (diagnostic timeout/cognitive forcing/Ely checklist/calibration), schema-based reasoning (Clinical Problem Solvers schemas: 按 pivot 症状走分支), reflective practice 结构化反思 (Mamede/Schmidt), 诊断错误科学 (NAM 2015 报告定义 / Newman-Toker Big Three / Hardeep Singh e-triggers / SAFER Dx 框架); (c) 行业结构与角色 — 医学生→实习/住院医 (晨会 morning report/查房被 pimping/汇报训练)→主治 attending→master clinician (NEJM CPC discussant/晨会大师如 Dhaliwal); 配套生态: 医学教育者 (clinical reasoning curriculum + 评估: script concordance test/key features exam/OSCE), 诊断安全研究者 (SIDM/AHRQ), 诊断辅助与 CDS 工具开发者 (DDx generator/AI); (d) 核心工作流 — 数据采集 (病史为王 + 循证体检 + 针对性检验影像) → 问题表征 (one-liner + semantic qualifiers) → 鉴别诊断生成 (schema / 解剖定位法 / VINDICATE-M 病因筛, 按『常见可能 × 致命不能漏 can't-miss』双轴排序) → 假设定向检验 (按 LR 选检查 / 阈值决策) → working diagnosis + 安全网 (red flags 交代 / test of time / test of treatment) → 反馈校准 (follow-up / M&M / diagnostic timeout); 教学工作流: 晨会渐进披露汇报 / CPC / SNAPPS / one-minute preceptor / virtual morning report; AI 增强工作流 (2023-2026: LLM 鉴别诊断头脑风暴 / OpenEvidence 检索 / ambient scribe 释放认知带宽 + 自动化偏倚 guardrails); (e) 产出物 — one-liner, problem list, prioritized DDx, assessment & plan (按问题分层), 晨会/CPC 汇报, M&M 复盘, 诊断不确定性沟通 (『最可能是 X, 但出现 Y 红旗立刻回来』); (f) 教育与评估 — script concordance test / key feature exam / EPA / 里程碑; 中国语境: 人卫《诊断学》教材 / 执业医师考试 / 规培结业临床思维考核; (g) 争议/批判 — debiasing 之争 (Croskerry vs Norman-Sherbino『knowledge is the cure』, 去偏 RCT 效果弱 / bias 标签不可证伪), 诊断错误率数字之争 (『10-15%』经典估计 / Newman-Toker 79.5 万美国年严重伤害外推方法被质疑 / 尸检符合率), dual-process 二分被批过度简化 (连续谱 / 难以实证分离), 决策规则 vs gestalt (资深 gestalt 常不输 Wells 类规则 / 算法厌恶), vignette 研究外推性 + context/case specificity (推理高度内容绑定不可通用迁移 [Norman/Eva] — 对『教推理通用课』产业的根本批判), AI 辅助诊断 2023-2026 (GPT-4 在 NEJM CPC/vignette 追平或超医生 [Kanjee 2023 JAMA / Goh 2024 JAMA Netw Open『AI alone > physician+AI』悖论] / Google AMIE / OpenEvidence 爆发 vs 自动化偏倚 / 去技能化 / 真实环境验证缺失), 防御性医疗与过度检查 (incidentaloma 瀑布 / VOMIT), 体检衰亡之争, pimping 教学法争议; (h) 流派/思想谱系 — 决策科学/Bayesian 派 (Ledley-Lusted 1959 → Elstein/Kassirer/Sox/Pauker/Eddy → Brush) vs 认知心理/双过程派 (Kahneman-Tversky → Croskerry/Graber) vs 教育认知派 (Schmidt/Boshuizen illness scripts → Norman/Eva/Mamede/Durning 情境认知) vs 诊断安全/系统派 (NAM 2015 / Newman-Toker / Hardeep Singh / Graber-SIDM: 错误=系统×认知共因) vs 床旁临床派 (Osler 传统 → Tierney aphorisms / Verghese / McGee / Dhaliwal / Saint: 病史体检为王 + 刻意练习) vs AI/计算派 (INTERNIST-1/DXplain 专家系统 → Isabel → LLM 世代 Rodman/Topol)。不含: 具体专科治疗方案与手术决策深度 (足踝外科/种植牙等另有 skill), 中医辨证 (另有 skill), EBM 文献批判性评价方法学 (相关但本 skill 聚焦诊断推理本身), 护理诊断体系 (NANDA), 影像/病理知觉型读片训练 (相邻但独立), 精神科 DSM 结构化访谈细节, 医患沟通技巧全集 (只覆盖诊断不确定性沟通), 患者自查/自我诊断指

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🇺🇸 Hardware + SaaS GTM Playbook — End-to-end go-to-market for consumer hardware products with software subscription models. Covers crowdfunding engineering (Kickstarter/Indiegogo/Makuake), KOL matrix for physical products, hardware PMF validation metrics, device-as-funnel subscription design, localization entry timing, and community flywheel mechanics. Built from verified Plaud, Insta360, and DJI case data. 🇨🇳 硬件+软件订阅 GTM 实操手册 — 面向消费硬件产品的完整出海及增长打法。覆盖众筹超额工程（KS/IGG/Makuake）、硬件 KOL 矩阵策略、硬件 PMF 验证、设备即漏斗订阅设计、本地化进入时机判断、社区飞轮构建。基于 Plaud/Insta360/大疆真实案例数据撰写。 🇯🇵 ハードウェア＋SaaS GTMプレイブック — クラウドファンディング（Kickstarter/IGG/Makuake）を起点とした消費者向けハードウェア製品のGTM戦略。KOLマトリクス、PMF検証、デバイスをファネルとするサブスクリプション設計、ローカライゼーション進入タイミング、コミュニティフライホイールまで網羅。Plaud・Insta360・DJIの実例データに基づく。 🇰🇷 하드웨어+SaaS GTM 플레이북 — 크라우드펀딩(Kickstarter/IGG/Makuake) 기반 소비자 하드웨어 제품의 엔드투엔드 GTM 전략. KOL 매트릭스, PMF 검증, 디바이스-as-퍼널 구독 설계, 현지화 진입 타이밍, 커뮤니티 플라이휠 포함. Plaud·Insta360·DJI 실제 사례 데이터 기반. Triggers: "hardware GTM" | "crowdfunding strategy" | "hardware+SaaS" | "Kickstarter launch" | "hardware KOL" | "hardware PMF" | "device subscription" | "hardware product launch" | "consumer hardware growth" | "Makuake" | "众筹策略" | "硬件出海" | "硬件+订阅" | "硬件GTM" | "KS众筹" | "硬件PMF" | "设备订阅" | "硬件冷启动" | "ハードウェアGTM" | "クラファン" | "하드웨어 GTM" | "크라우드펀딩"

Use smartcrop when an agent needs to choose a sensible crop automatically instead of center-cropping every image. The workflow scores visual saliency, returns crop coordinates for a target aspect ratio, and hands those coordinates to an image pipeline that renders the final thumbnail or social card.

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Schedule recurring tasks and heartbeat monitoring using Claude Code's cron system (CronCreate/CronList/CronDelete). Implements the Agentic Heartbeat Pattern for ecosystem health monitoring.

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Debug or validate Pulp animations / transitions / scroll behavior using in-process motion fixtures and offline visual analysis. TRIGGER on phrases like "animation is wrong", "transition timing off", "fade too late", "card slides too far", "scroll jumps on restore", "scroll offset wrong on restore", "frame jump in the timeline", "easing looks wonky", "imported Figma motion doesn't match source", "settle time / overshoot / drift / monotonic", "what value does the knob reach at frame N", "record this animation so I can replay it", "this animation is expensive — which one and why", "reduced-motion broken", "scrub a captured fixture". Captures fixtures (.motion.jsonl), and ships assertion helpers (is_monotonic / settling_time_seconds / overshoot / start_delay_seconds / final_value / local_step_outlier_ratio) and the `scroll_geometry` trace for `ScrollView` content-offset / visible-rect / content-size observability. Off by default in prod.

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Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq data across donors, labs, and platforms. Follows the Mawla et al. 2019 framework for assessing cross-study reproducibility, TIN-based quality filtering, and detection-limit-aware interpretation. Handles batch correction (Harmony/Seurat), dropout awareness, cross-contamination artifacts, and platform-specific biases. Use this skill for ANY scRNA-seq integration task, cross-dataset comparison, cell atlas construction, or reproducibility assessment involving ENCODE single-cell data.

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Audit Microsoft Advertising measurement, UET, search and audience campaigns, Google imports, syndication, keywords, creative, bidding, budgets, Copilot inventory, and policy. Use for Microsoft Ads, Bing Ads, UET, Microsoft Audience Network, Google Ads import, or Microsoft campaign optimization.

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Verify, customize, or opt out of moflo's AUTOMATIC durable-learning sharing across git worktrees / Conductor workspaces on one machine. As of the worktree-auto-sharing change this is on by default — learnings converge across a repo's worktrees with no setup. Use when the user asks "is memory shared across my worktrees?", "where are my worktree learnings stored?", "turn off worktree memory sharing", "share learnings across my separate clones", or "point my worktrees at a custom store". For a team or cross-machine (git-tracked) sharing, use /memory-team instead.

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Detect syntenic blocks and structural rearrangements between genomes using MCScanX (Wang 2012), JCVI/MCScan (Tang 2008 Python), GENESPACE (Lovell 2022) for orthology-anchored riparian visualization, SyRI for structural variation, AnchorWave for sequence-level synteny, i-ADHoRe 3.0 for highly diverged species, SynNet for synteny networks, and ntSynt for multi-genome macrosynteny. Use when identifying collinear gene blocks across species, distinguishing macrosynteny from microsynteny, detecting inversions/translocations/duplications, anchoring orthology in WGD lineages, producing publication riparian plots, computing synteny block age via Ks (cross-references whole-genome-duplication), or running synteny-aware ortholog inference in polyploids.

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Use when reviewing a .NET pull request for breaking changes that may affect other microservice repositories. Detects cross-repo API, DTO, endpoint, EF entity, and NuGet-package breaks, and checks whether a compatible downstream PR already exists. Keywords: cross-repo impact, breaking change, microservice compatibility, downstream break, compatible PR, blast radius review, api compatibility, contract break, dto shape change, endpoint break.

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Especialista em construir experiências imersivas baseadas em scroll - storytelling por paralaxe, animações de scroll, narrativas interativas e experiências web cinematográficas. Como as interativas do NY Times, páginas de produtos da Apple e experiências web premiadas. Torna websites em experiências, não apenas páginas. Use quando: animação de scroll, paralaxe, storytelling de scroll, história interativa, website cinematográfico.

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The migration step and the package-owned-table exception — NOT the normal collection flow. For app collections use the crouton CLI/skill (schema JSON → `crouton config`); reach here when you then need to generate/apply the Drizzle migration and hit the schema.mjs-only-after-build gotcha ("No schema files found"), or when adding a package-owned infra table (the crouton-flow pattern) that does NOT go through `crouton config`.

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System reference for the crouton layout engine (@fyit/crouton-layout) — the LayoutTree/layout_configs data model, the croutonLayoutBlocks registry and sizing contract, the viability metric, the deterministic placer (#709), and how layouts persist and seed. Use when reasoning about WHY a layout renders/composes/persists the way it does, when a question is shaped like "what is a LayoutTree / where do layouts live / why did the placer pick this arrangement / why won't this pane shrink / where does minWidth get read", or when a generated POC boots with the wrong (or no) default layout. Trigger phrases: "layout tree", "layout_configs", "viability check", "composeDefaultLayout", "block sizing contract", "why is my layout not viable". For authoring a block component, use the block-authoring skill instead.

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