「definitions」の検索結果

Tracks ctDNA across serial liquid-biopsy timepoints for molecular residual disease (MRD) and treatment-response monitoring, treating MRD as a binary integrated detection call across the patient's full variant set (with a defined LoD95 and per-sample specificity) rather than a per-timepoint VAF threshold, and handling undetectable samples as left-censored at the per-sample limit of detection rather than true zeros. Covers tumor-informed bespoke vs tumor-naive design, landmark vs surveillance sampling, molecular-response definitions and their non-standardization, censoring-aware clearance kinetics, and the multiple-testing structure of repeated surveillance. Use when monitoring ctDNA during therapy, calling molecular relapse before imaging, or estimating clearance half-life from serial samples.

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Infers person-to-person transmission from pathogen genomes using outbreaker2, TransPhylo, phybreak, BadTrIP, SCOTTI, BEASTLIER, and SNP-distance / cluster-picker approaches (HIV-TRACE for HIV; transcluster). Defines outbreak clusters using pathogen-specific SNP thresholds (NOT a universal cutoff -- TB <=12 SNPs; MRSA <=15; C. difficile <=2; Klebsiella <=21), models within-host diversity and transmission bottlenecks, integrates contact-tracing data, distinguishes generation from serial interval, and attributes source via Bayesian source attribution (islandR). Use when investigating outbreaks for who-infected-whom, defining SNP-cluster outbreak definitions, accounting for unsampled intermediates, choosing between outbreaker2 (rich epi data) and TransPhylo (genomic-only after a dated phylogeny), running source attribution between host populations, calling HIV-TRACE thresholds appropriate to the local subtype, or distinguishing recent transmission from reactivation in TB or chronic HIV.

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AWS ECS container orchestration for running Docker containers. Use when deploying containerized applications, configuring task definitions, setting up services, managing clusters, or troubleshooting container issues.

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Convert Lanelet2 maps (.osm) to RoadRunner HD Map (.rrhd) format using MATLAB. Use when converting Lanelet2 maps into RoadRunner Scene Builder, building driving scenes from open-source map data, or transforming road network definitions for simulation.

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Deploy containers on ECS and Fargate. Configure task definitions, services, and load balancing. Use when running containerized workloads on AWS.

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Define and generate the manual-first evidence pack for high-risk work. Covers 6 high-risk class definitions and the 5-artifact schema required before finalizing, pushing, or handing off.

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Scan Express.js source files to discover all API route definitions.

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Review the configured cost alert rules and the alerts currently fired on the Agent Monitor dashboard, then explain exactly what tripped and why. Uses /api/alerts (fired feed) and /api/alerts/rules (definitions). Use when checking spend alerts or asking why a cost alarm went off.

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TOM and ADOMD.NET guidance via PowerShell for connecting to Power BI Desktop's local Analysis Services instance. Covers model enumeration, DAX queries, metadata modification, annotations, calendar definitions, field parameters, query tracing, DAX library package management (daxlib.org), and the Desktop Bridge for reloading and screenshotting the report canvas. Automatically invoke when the user mentions "Power BI Desktop", "Analysis Services port", "TOM", "ADOMD", "daxlib", "DAX library", "DAX UDF package", or asks to "connect to PBI Desktop", "query PBI Desktop with DAX", "modify PBI Desktop model", "add a measure to PBI", "capture visual queries", "create a field parameter", "validate DAX", "intercept DAX queries", "install daxlib", "add DAX SVG", "add IBCS", "reload the report canvas", "screenshot a report page", "Desktop Bridge", or to work with the model and report in Power BI Desktop together.

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Build responsive, mobile-first layouts using fluid containers, flexible units, media queries, and touch-friendly design that works across all screen sizes. Use this skill when creating or modifying UI layouts, responsive grids, breakpoint styles, mobile navigation, or any interface that needs to adapt to different screen sizes. Apply when working with responsive CSS, media queries, viewport settings, flexbox/grid layouts, mobile-first styling, breakpoint definitions (mobile, tablet, desktop), touch target sizing, relative units (rem, em, %), image optimization for different screens, or testing layouts across multiple devices. Use for any task involving multi-device support, responsive design patterns, or adaptive layouts.

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Use when comparing process cohorts, departments, periods or before-and-after results under matched definitions.

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Configures environment variables for Power Pages site settings to support ALM across environments. Creates environment variable definitions in Dataverse, guides the user through linking site settings to those variables via the Power Pages Management app, adds the variables to the solution, and generates a deployment-settings.json file with per-stage override values. Use when asked to: "configure environment variables", "add env vars", "set up deployment variables", "make site settings environment-specific", "configure ALM variables", "set up env-specific settings", "add deployment settings", "configure per-environment settings".

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Use when structuring Unity 6.3 C# code: ScriptableObject data vs runtime state, events and services, inventory, health, save and load, Input System actions and key rebinding, async with Awaitable, assembly definitions, Enter Play Mode and domain reload, .meta files, Git, Smart Merge and LFS. Also when 'my save works in the Editor but not in the build', statics keep values on the second Play, events fire twice or never, an await runs after its object died, rebinds are lost on relaunch, a renamed class loses its data, a scene merge breaks.

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Expert guidance on setting up and using Retrofit for type-safe HTTP networking in Android. Covers service definitions, coroutines, OkHttp configuration, and Hilt integration.

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Generate a phased delivery orchestration plan for creative-direction-driven work: which skills run when, what locks at which gate, how handoffs occur, and how the cadence implements in the team's tools (Jira, Linear, Notion, Figma, GitHub) with AI agents via MCP and CLI. A temporal map of phases, lock points, handoff specs, gate definitions, and QA verification gates. Distinct from `creative-brief` (static project brief) and `creative-direction` (aesthetic direction). Triggers on integration orchestrator, delivery cadence, project orchestration, when does the brief lock, how to phase creative direction, design-development handoff, QA gate, agent-driven QA, and when a creative-direction project is starting, mid-flight with broken cadence, or integrating AI agents into PM workflow. Does NOT fire for project scoping (use `creative-brief`), aesthetic direction (use `creative-direction`), or general project management without a creative-direction throughline.

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Running experiments out of the data warehouse instead of via dedicated experiment platforms. SQL-based assignment, exposure logging discipline, metric definitions in dbt models, statistical analysis in SQL or Python, variance reduction with CUPED, sequential testing, and the operational tradeoffs vs platforms like Statsig and Optimizely. Triggers on warehouse-native experimentation, run experiments in BigQuery, run experiments in Snowflake, dbt experiments, SQL t-test, CUPED variance reduction, exposure log, sample ratio mismatch, sequential testing, mSPRT, doubly robust estimation, build vs buy experimentation. Also triggers when the team is choosing between platform and warehouse, building warehouse-native experiment infrastructure, auditing one, or running an experiment with a custom metric the platform cannot handle.

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Build MCP (Model Context Protocol) servers with tool definitions, resource providers, prompt templates, and transports. Use when exposing APIs to AI agents, building tool servers, converting OpenAPI to MCP, or creating MCP integrations.

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Generate API test suites from route definitions across frameworks: auth, input validation, contract, k6 load testing, mocking, and OpenAPI-driven generation. Use when adding new APIs, auditing test coverage, or building regression suites.

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Universal MCP client for connecting to any MCP server with progressive disclosure. Wraps MCP servers as skills to avoid context window bloat from tool definitions. Use when interacting with external MCP servers (Zapier, Sequential Thinking, GitHub, filesystem, etc.), listing available tools, or executing MCP tool calls. Triggers on requests like "connect to Zapier", "use MCP server", "list MCP tools", "call Zapier action", "use sequential thinking", or any MCP server interaction.

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Initialize a Harness Engineering framework in the current project. Use when user says 'harness', 'init harness', 'initialize framework', 'setup harness engineering', '/harness', or wants to set up a Plan-Build-Verify development workflow with specialized agents (planner, generator, evaluator). Creates CLAUDE.md, agent definitions, command templates, hooks, and documentation structure for autonomous AI-driven development.

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Guide for implementing TypeScript in projects, including naming conventions, type definitions, and code style. Triggered when writing or refactoring TypeScript code.

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Best practices for polars data processing with dataframely. Covers definitions of Schema and Collection, usage of .validate() and .filter(), type hints, and testing. Use when writing or modifying code involving dataframely or polars data frames.

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Monitoring, observability, operational procedures, CI/CD lessons learned, and quality gate definitions. Load when assessing production readiness or validating operational excellence.

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Step-by-step workflow for converting bloated command files to lean declarative definitions

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