「filter」の検索結果

Chains a somatic (tumor-normal) SNV/indel and structural-variant pipeline end to end with GATK Mutect2 (or Strelka2), wiring the somatic-specific machinery - panel-of-normals and gnomAD germline-resource priors, GetPileupSummaries/CalculateContamination, and LearnReadOrientationModel FFPE/oxoG orientation-bias filtering fed into FilterMutectCalls. Use when calling somatic mutations from a tumor-normal pair (or tumor-only with PoN caveats), deciding which artifact filter removes which class of false positive, reasoning about VAF/purity/ploidy and clonal-vs-subclonal detection, adding somatic SV/CNV or TMB/MSI/signatures, or routing variants to AMP/ASCO/CAP tier and oncogenicity interpretation (never germline ACMG).

日本語の概要は準備中です。原文の説明を表示しています。

Medicinal chemistry filters. Apply drug-likeness rules (Lipinski, Veber), PAINS filters, structural alerts, complexity metrics, for compound prioritization and library filtering.

日本語の概要は準備中です。原文の説明を表示しています。

Build content filtering for AI outputs. TRIGGERS - Use when user needs help with ai-content-filter related tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Extracts, filters, annotates, and exports differential expression results from DESeq2 or edgeR with proper handling of padj=NA (independent filtering, Cook's outliers, all-zero), multiple-testing correction choice (BH vs Storey q-value vs IHW vs lfsr), TREAT vs post-hoc fold-change filtering, p-value histogram diagnostics, gene annotation via org.db/biomaRt/mygene, GSEA preranked input, ORA background construction, replication reality (Schurch 2016 small-n result), and SABV/sex-stratified reporting. Use when extracting and interpreting DE results, troubleshooting padj=NA, choosing FDR method, preparing ranked lists for pathway analysis, annotating gene IDs, or comparing DESeq2 vs edgeR outputs.

日本語の概要は準備中です。原文の説明を表示しています。

Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.

日本語の概要は準備中です。原文の説明を表示しています。

Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and consort. Use when showing how entities move between categories across timepoints (cell states, drug response classes, patient flow through a trial) or filtering pipelines (variants filtered through QC stages).

日本語の概要は準備中です。原文の説明を表示しています。

Create or edit the Universal Editor component configuration (component-definition.json, component-models.json, component-filters.json) for AEM Edge Delivery Services blocks. Use this skill whenever the user mentions component models, component definitions, component filters, block configuration for the Universal Editor, UE block setup, adding a new block to UE, configuring block properties, block authoring fields, or any task involving the three JSON config files that control how blocks appear in the Universal Editor. Also trigger when the user wants to create a new EDS/Franklin block with UE support, modify block fields, add a block to the section filter, or asks about how blocks connect to the Universal Editor.

日本語の概要は準備中です。原文の説明を表示しています。

Extracts, filters, annotates, and exports differential expression results from DESeq2 or edgeR with proper handling of padj=NA (independent filtering, Cook's outliers, all-zero), multiple-testing correction choice (BH vs Storey q-value vs IHW vs lfsr), TREAT vs post-hoc fold-change filtering, p-value histogram diagnostics, gene annotation via org.db/biomaRt/mygene, GSEA preranked input, ORA background construction, replication reality (Schurch 2016 small-n result), and SABV/sex-stratified reporting. Use when extracting and interpreting DE results, troubleshooting padj=NA, choosing FDR method, preparing ranked lists for pathway analysis, annotating gene IDs, or comparing DESeq2 vs edgeR outputs.

日本語の概要は準備中です。原文の説明を表示しています。

Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.

日本語の概要は準備中です。原文の説明を表示しています。

Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and consort. Use when showing how entities move between categories across timepoints (cell states, drug response classes, patient flow through a trial) or filtering pipelines (variants filtered through QC stages).

日本語の概要は準備中です。原文の説明を表示しています。

Process multimedia files with FFmpeg (video/audio encoding, conversion, streaming, filtering, hardware acceleration), ImageMagick (image manipulation, format conversion, batch processing, effects, composition), and RMBG (AI-powered background removal). Use when converting media formats, encoding videos with specific codecs (H.264, H.265, VP9), resizing/cropping images, removing backgrounds from images, extracting audio from video, applying filters and effects, optimizing file sizes, creating streaming manifests (HLS/DASH), generating thumbnails, batch processing images, creating composite images, or implementing media processing pipelines. Supports 100+ formats, hardware acceleration (NVENC, QSV), and complex filtergraphs.

日本語の概要は準備中です。原文の説明を表示しています。

Create or edit the Universal Editor component configuration (component-definition.json, component-models.json, component-filters.json) for AEM Edge Delivery Services blocks. Use this skill whenever the user mentions component models, component definitions, component filters, block configuration for the Universal Editor, UE block setup, adding a new block to UE, configuring block properties, block authoring fields, or any task involving the three JSON config files that control how blocks appear in the Universal Editor. Also trigger when the user wants to create a new EDS/Franklin block with UE support, modify block fields, add a block to the section filter, or asks about how blocks connect to the Universal Editor.

日本語の概要は準備中です。原文の説明を表示しています。

Implements content safety filters with PII redaction, policy constraints, prompt injection detection, and safe refusal templates. Use when adding "content moderation", "safety filters", "PII protection", or "guardrails".

日本語の概要は準備中です。原文の説明を表示しています。

NotionのページをMarkdownで取得・作成・更新し、データの絞り込みや検索を行います。ファイル、コメント、Workersの操作も扱うスキルです。

• Markdownからページを作成・更新したいとき
• データベースの記録を絞り込みたいとき
• ページ検索やコメント確認をしたいとき

PubMedで医学・生命科学の文献を探し、統制語や条件を使った検索式の作成、抄録・書誌情報の取得、再現可能な検索記録の整理を支援するスキル。

• 研究テーマの医学論文を探したいとき
• 主題語と期間で検索式を作りたいとき
• PMIDから抄録・書誌情報を取得

Cisco IOS／IOS-XEの設定をレビューし、通信の許可・拒否ルールやインターフェースの確認、障害調査用コマンドの選定、変更前後の検証を支援します。

• 変更前のルーター・スイッチ設定レビュー
• 読み取り専用コマンドで障害を調べたいとき
• ACLのマスクと適用方向の確認

文章などを数値化して似た内容を探す検索をQdrantで実装。属性による絞り込みやAI回答用の資料検索から、大規模運用の設定・調整まで支援します。

• AI回答用の参考資料を検索したいとき
• カテゴリや日時で絞る類似検索
• リアルタイム推薦の実装

Automate Dnsfilter tasks via Rube MCP (Composio). Always search tools first for current schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Use when auditing URL structure or configuring search engine handling of filtered, sorted, or tracked URLs. Applies to e-commerce sites, filtered content directories, and any site appending tracking or session parameters.

日本語の概要は準備中です。原文の説明を表示しています。

Create and edit Obsidian Bases (.base files) with views, filters, formulas, and summaries. Use when working with .base files, creating database-like views of notes, or when the user mentions Bases, table views, card views, filters, or formulas in Obsidian.

日本語の概要は準備中です。原文の説明を表示しています。

Applies medicinal chemistry filters for compound triage, using drug-likeness rules (Lipinski, Veber, CNS), structural alert catalogs (PAINS, NIBR, ChEMBL), complexity metrics, and the medchem query language for library filtering.

日本語の概要は準備中です。原文の説明を表示しています。

Credit risk data cleaning and variable screening pipeline for pre-loan modeling. Use when working with raw credit data that needs quality assessment, missing value analysis, or variable selection before modeling. it covers data loading and formatting, abnormal period filtering, missing rate calculation, high-missing variable removal,low-IV variable filtering, high-PSI variable removal, Null Importance denoising, high-correlation variable removal, and cleaning report generation. Applicable scenarios arecredit risk data cleaning, variable screening, pre-loan modeling preprocessing.

日本語の概要は準備中です。原文の説明を表示しています。

Fundamental factor screening — filter stocks by PE/PB/ROE, financial statement fields, and other metrics for value or growth selection. Supports A-shares (via tushare extra_fields or fundamental_fields) and HK/US stocks (via yfinance Ticker info).

日本語の概要は準備中です。原文の説明を表示しています。

Detect WMI event subscription persistence (MITRE T1546.003) by analyzing Sysmon Event IDs 19, 20, and 21 for malicious EventFilter, EventConsumer, and FilterToConsumerBinding creation, cross-referenced against root\subscription namespace contents and Sysinternals Autoruns. Use when hunting WMI-based persistence, triaging a Sysmon alert on these event IDs, or during incident response and purple-team validation of WMI defenses.

日本語の概要は準備中です。原文の説明を表示しています。